Abstract: This invention relates to compositions, and methods of use thereof, for (i) enhancing executive cognitive function(s) (for example, decision making, planning, working memory, multitasking, judgment, numerical problem-solving, reading comprehension), and/or (ii) increasing blood flow in brain vasculature, comprising administering to a subject in need thereof, certain polyphenols such as flavanols, procyanidins, or pharmaceutically acceptable salts or derivatives thereof.

Abstract: A hydrogen fueling system and method comprises a container, a first tank, second tank, and third tank disposed within the container, and a nozzle coupled to the second tank and the third tank. One or more computer-readable storage media storing instructions executable by one or more processors may control flow of liquid hydrogen and hydrogen gas in the system, adjust temperature of the tanks, control pressure in the tanks, and transfer hydrogen gas from the second tank, the third tank, or a combination thereof to one or more target vessels. The system may also comprise flow control assemblies and flow control valves to manage the transfer of liquid hydrogen and hydrogen gas in the system.

Abstract: A method of producing an ethylenically unsaturated carboxylic acid or ester, preferably an ?, ? ethylenically unsaturated carboxylic acid or ester. The method includes contacting formaldehyde or a suitable source thereof with a carboxylic acid or ester in the presence of a catalyst and optionally in the presence of an alcohol. The catalyst includes a nitrided metal oxide having at least two types of metal cations, M1 and M2, wherein M1 is selected from the metals of group 2, 3, 4, 13 (called also IIIA) or 14 (called also IVA) of the periodic table and M2 is selected from the metals of groups 5 or 15 (called also VA) of the periodic table.

Abstract: In a reclosable folding box (41, 42, 43) having a safety and tamper-evident closure (84), the side wall surfaces (2 to 6, 64, 65) of which are formed by a one-piece blank (1, 1a, 1b) and glued together in such a way that the folding box (41, 42, 43) cannot be opened without destroying a glued joint and/or at least one disconnectable tear line area (16, 17, 16a, 16b, 17a, 17b), a solution for a reclosable medical packaging having a safety and tamper-evident closure is to be created, which provides an improved graspability and visual recognizability of a pull tab forming at least the substantial part of the safety and tamper-evident closure.

Abstract: A machine learning model for predicting a size fit satisfaction for a variable size component is trained using at least sizing profiles of a plurality of items and feedbacks of subjects regarding sizing of the plurality of items. The machine learning model is used to determine a value for the variable size component that corresponds to an optimal predicted size fit satisfaction. The determined value of the variable size component is provided for use in creating a new item with a sizing variation based on the determined value.

Abstract: A turbomachine fan blade preform (10) comprising a pair of mutually opposing panels (12), and a membrane (20) sandwiched between the pair of panels (12). The membrane (20) is of a non-uniform thickness. The thickness of at least a portion of the membrane tapers along its length and/or width, between a relative thicker first region and relatively thinner second region.

Abstract: A process for regenerating a silica-supported depleted alkali metal catalyst is described. The level of alkali metal on the depleted catalyst is at least 0.5 mol % and the silica support is a zero-gel. The process comprises the steps of contacting the silica supported depleted alkali metal catalyst with a solution of a salt of the alkali metal in a solvent system that has a polar organic solvent as the majority component. A re-impregnated catalyst prepared by the process of the invention any comprising a silica zero-gel support and a catalytic metal selected from an alkali metal in the range 0.5-5 mol % on the catalyst, wherein the surface area of the silica support is <180 m2/g is also described. The invention is applicable to a process for preparing an ethylenically unsaturated acid or ester comprising contacting an alkanoic acid or ester of the formula R1—CH2—COOR3, with formaldehyde or a suitable source of formaldehyde.

Abstract: This invention relates to compositions, and methods of use thereof, for (i) enhancing executive cognitive function(s) (for example, decision making, planning, working memory, multitasking, judgment, numerical problem-solving, reading comprehension), and/or (ii) increasing blood flow in brain vasculature, comprising administering to a subject in need thereof, certain polyphenols such as flavanols, procyanidins, or pharmaceutically acceptable salts or derivatives thereof.

Abstract: A test cell (10) for containing equipment (12) subject to pressure testing comprises a plurality of metal plate wall panels (14) and a mesh roof panel (16) formed from mesh strands (26) of a high strength material. Each wall panel has a lapped connection (18) with an adjacent wall panel. The mesh panel (16) may be formed from a ballistic fabric, and the mesh strands (26) may be wire, rope and braid of steel, metal, plastic, natural or composite fiber, or a combination thereof. In the event of a pressure failure of the equipment (12) under test, the roof panel (16) captures fragments of the equipment while allowing the dissipation of pressure shock waves through the apertures (28) in the mesh. The lapped connections (18) between wall panels (14) result in increased friction between adjacent wall panels (14) and thus an increase in the strength of the connection when subject to pressure shock waves.

Abstract: The present invention relates to methods for processing jobs within a cluster architecture. One method comprises the pausing of a job when waiting upon external dependencies. Another method comprises the transmission of messages relating to the ongoing processing of jobs back to a client via a persistent messaging channel. Yet another method comprises determining capacity at a node before allocating a job for processing by the node or adding the job to a cluster queue. A system for processing jobs within a cluster architecture is also disclosed.

Abstract: Controlled access to a physical area or secured service is managed using sonic tones. A secret key is stored in a user device and in a security system, and then when access is desired, the secret key or a derivative thereof is encoded into a sonic tone which is transmitted. The sonic tone is received and decoded to obtain the encoded binary message, which is then compared to an expected binary message, and if there is a match, access is granted by the security system. In illustrated particular embodiments the secret key is used to generate a one-time password based upon the secret key and a randomizing factor, such as the current time.

Abstract: Systems, devices, and methods for eyebox expansion in wearable heads-up displays (WHUD) are described. A WHUD includes a support structure, a scanning laser projector (SLP), a split mirror, an optical splitter, and a holographic combiner. When the WHUD is worn on the head of a user the holographic combiner is positioned in a field of view of the user. The SLP scans light signals onto the split mirror which reflects the light signals onto the optical splitter. The optical splitter redirects the light signals towards the holographic combiner such that subsets of the light signals originate from spatially-separated virtual positions. The holographic combiner redirects the light to the eye resulting in spatially-separated exit pupils. The spatial separation of the exit pupils results in an expanded eyebox. The indirect path of light from SLP to optical splitter enables a smaller and therefore more aesthetically desirable design for the WHUD.

Abstract: Systems, devices, and methods for eyebox expansion in wearable heads-up displays (WHUD) are described. A WHUD includes a support structure, a scanning laser projector (SLP), a split mirror, an optical splitter, and a holographic combiner. When the WHUD is worn on the head of a user the holographic combiner is positioned in a field of view of the user. The SLP scans light signals onto the split mirror which reflects the light signals onto the optical splitter. The optical splitter redirects the light signals towards the holographic combiner such that subsets of the light signals originate from spatially-separated virtual positions. The holographic combiner redirects the light to the eye resulting in spatially-separated exit pupils. The spatial separation of the exit pupils results in an expanded eyebox. The indirect path of light from SLP to optical splitter enables a smaller and therefore more aesthetically desirable design for the WHUD.

Abstract: An interconnect for an integrated circuit communicating transactions between initiator Intellectual Property (IP) cores and multiple target IP cores coupled to the interconnect is generally described. The interconnect routes the transactions between the target IP cores and initiator IP cores in the integrated circuit. A first aggregate target of the target IP cores includes two or more memory channels that are interleaved in an address space for the first aggregate target in the address map. Each memory channel is divided up in defined memory interleave segments and then interleaved with memory interleave segments from other memory channels. An address map is divided up into two or more regions. Each interleaved memory interleave segment is assigned to at least one of those regions and populates the address space for that region, and parameters associated with the regions and memory interleave segments are configurable.

Abstract: A system and method are provided for connecting a device to an automotive diagnostic port of a vehicle. The method includes the steps of sampling a signal on each pin of a plurality of pins of the automotive diagnostic port to generate a signal map corresponding with the automotive diagnostic port, selecting a configuration from a list of configurations for the automotive diagnostic port based on the signal map, establishing communication with the vehicle via the automotive diagnostic port based on the selected configuration. The method may be performed by a system that includes at least one of a device connected to the automotive diagnostic port of a vehicle, a mobile device, and/or a server.

Abstract: The present invention relates to methods for treating or preventing cancer and metastasis. More particularly, the present invention relates to methods for treating or preventing cancer by decreasing the expression and/or activity of Flightless I. Also provided are methods for inhibiting the growth of a cancerous cell and methods for inhibiting formation and/or growth of a tumour which also rely on decreasing the expression and/or activity of Flightless I. The present invention also extends to methods for diagnosing cancer, methods for determining if a subject is susceptible to developing cancer, and methods for assessing progression of cancer based on the finding that increased expression and/or activity of Flightless I is associated with cancer development, growth and metastasis. The present invention also provides methods for screening for a candidate therapeutic agent useful for treating or preventing cancer, and related pharmaceutical compositions and kits.

Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death Ligand 1 receptor (PD-L1) and another therapeutic agent, and the use of the combination therapies for the treatment of cancer.

Abstract: Some examples include determining the condition of photovoltaic modules at one or more points in time, in particular using line-scanning luminescence imaging techniques. One or more photoluminescence and/or electroluminescence images of a module may be acquired and processed using one or more algorithms to provide module data, including the detection of defects that may cause or may have caused module failure. Additionally, some examples include determining the condition of photovoltaic modules, such as throughout the production, transport, installation and service life of the photovoltaic modules.