Abstract: A series of substituted benzimidazole, imidazo[1,2-a]pyridine and pyrazolo[1,5-a]pyridine derivatives, and analogues thereof, being potent modulators of human TNF? activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.

Abstract: Many indoor location services do not require precise knowledge of the position of a mobile device, but simply whether a mobile device is within a particular zone of an indoor area. Existing signals in an indoor space may provide enough information to distinguish between different zones of an indoor area, allowing a server to provide indoor location services without requiring the installation of new signal sources in the indoor area.

Abstract: A user interface method is disclosed. For a particular interface, such as a touch input device, the method involves defining an enablement protocol for a function and recording and retaining the enablement protocol of said function, such that a user enables the function by substantially reproducing the enablement protocol in the absence of spatial or temporal indication of at least a portion of the enablement protocol.

Abstract: This invention relates to compositions, and methods of use thereof, for (i) enhancing executive cognitive function(s) (for example, decision making, planning, working memory, multitasking, judgment, numerical problem-solving, reading comprehension), and/or (ii) increasing blood flow in brain vasculature, comprising administering to a subject in need thereof, certain polyphenols such as flavanols, procyanidins, or pharmaceutically acceptable salts or derivatives thereof.

Abstract: A method of producing an ethylenically unsaturated carboxylic acid or ester such as (meth) acrylic acid or alkyl esters thereof, for example, methyl methacrylate is described. The process comprises the steps of contacting formaldehyde or a suitable source thereof with a carboxylic acid or ester, for example, propionic acid or alkyl esters thereof in the presence of a catalyst and optionally an alcohol. The catalyst comprises group II metal phosphate crystals having rod or needle like morphology or a suitable source thereof. The phosphate may be a hydroxyapatite, pyrophosphate, hydroxyphosphate, PO42? phosphate or mixtures thereof. The group II metal may be selected from Ca, Sr, Ba or mixtures thereof, for example, strontium hydroxyapatite and calcium hydroxyapatite. A catalyst system comprising a crystalline metal phosphate catalyst and a catalyst support is also described. The metal phosphate has rod/needle like morphology.

Abstract: The invention relates to a method of producing an ethylenically unsaturated carboxylic acid or ester, preferably an ?, ? ethylenically unsaturated carboxylic acid or ester. The method includes contacting formaldehyde or a suitable source thereof with a carboxylic acid or ester in the presence of a catalyst and optionally in the presence of an alcohol. The catalyst comprises a nitrided metal oxide having at least two types of metal cations, M1 and M2, wherein M1 is selected from the metals of group 2, 3, 4, 13 (called also IIIA) or 14 (called also IVA) of the periodic table and M2 is selected from the metals of groups 5 or 15 (called also VA) of the periodic table. The invention extends to a catalyst system.

Abstract: A turbomachine fan blade preform (10) comprising a pair of mutually opposing panels (12), and a membrane (20) sandwiched between the pair of panels (12). The membrane (20) is of a non-uniform thickness. The thickness of at least a portion of the membrane tapers along its length and/or width, between a relative thicker first region and relatively thinner second region.

Abstract: A method for obtaining accurate call path information in a mixed-mode environment where interpreted methods and non-interpreted methods can call one another is disclosed. In one embodiment, such a method includes generating an event and recording it in a buffer when an interpreted method calls an interpreted method. The method also generates an event and records it in the buffer when an interpreted method calls a non-interpreted method. The method further generates an event and records it in the buffer when a non-interpreted method calls an interpreted method. The method refrains from generating an event when a non-interpreted method calls a non-interpreted method. A corresponding apparatus and computer program product are also disclosed.

Abstract: Disclosed are apparatus and methods for calling software methods. A computing device can receive a request to call a software method of a class instance which can include an interface method table and a virtual method table (vtable). The interface method table can include interface method table entries, which can include a particular interface method table entry for a particular interface method of a software interface associated with the class instance. The particular interface method table entry can refer to the particular interface method. The vtable can include vtable entries, which can include a particular vtable entry for a particular virtual method associated with the class instance. The particular vtable entry can refer to the particular virtual method. The computing device can determine an entry point for the called software method based on the interface method table and/or the vtable. The computing device can call the called software method by executing instructions at the entry point.

Abstract: A battery pack includes a plurality of prismatic format batteries in a stacked configuration. Flexible graphite sheet heat spreaders are interposed between adjacent prismatic batteries in the stack. A heat sink extends the length of the stack of prismatic format batteries. But heat spreader major surfaces contact the heat sink and extend into the heat sink by at least 30 percent of the thru-thickness of the heat sink.

Abstract: A hydrogen fueling system and method comprises a container, a first tank, second tank, and third tank disposed within the container, and a nozzle coupled to the second tank and the third tank. One or more computer-readable storage media storing instructions executable by one or more processors may control flow of liquid hydrogen and hydrogen gas in the system, adjust temperature of the tanks, control pressure in the tanks, and transfer hydrogen gas from the second tank, the third tank, or a combination thereof to one or more target vessels. The system may also comprise flow control assemblies and flow control valves to manage the transfer of liquid hydrogen and hydrogen gas in the system.

Abstract: A method of producing an ethylenically unsaturated carboxylic acid or ester such as (meth) acrylic acid or alkyl esters thereof, for example, methyl methacrylate is described. The process comprises the steps of contacting formaldehyde or a suitable source thereof with a carboxylic acid or ester, for example, propionic acid or alkyl esters thereof in the presence of a catalyst and optionally an alcohol. The catalyst comprises group II metal phosphate crystals having rod or needle like morphology or a suitable source thereof. The phosphate may be a hydroxyapatite, pyrophosphate, hydroxyphosphate, PO42? phosphate or mixtures thereof. The group II metal may be selected from Ca, Sr, Ba or mixtures thereof, for example, strontium hydroxyapatite and calcium hydroxyapatite. A catalyst system comprising a crystalline metal phosphate catalyst and a catalyst support is also described. The metal phosphate has rod/needle like morphology.

Abstract: A method, apparatus, and system are described, which generally relate to an interconnect routing transactions to target IP cores, including two or more channels making up a first aggregate target. The two or more channels populate an address space assigned to the first aggregate target and appear as a single target to the initiator IP cores. The interconnect implements chopping logic to chop an individual transaction from a first initiator IP core whose address sequence crosses a channel address boundary from a first channel to a second channel within the first aggregate target into two or more burst transactions. A first chopped burst transaction is chopped to fit within the address boundaries of the first channel and a second chopped burst transaction is chopped to fit within the address boundaries of the second channel.

Abstract: This invention relates to compositions, and methods of use thereof, for (i) enhancing executive cognitive function(s) (for example, decision making, planning, working memory, multitasking, judgment, numerical problem-solving, reading comprehension), and/or (ii) increasing blood flow in brain vasculature, comprising administering to a subject in need thereof, certain polyphenols such as flavanols, procyanidins, or pharmaceutically acceptable salts or derivatives thereof.

Abstract: A user interface method is disclosed. For a particular interface, such as a touch input device, the method involves defining an enablement protocol for a function and recording and retaining the enablement protocol of said function, such that a user enables the function by substantially reproducing the enablement protocol in the absence of spatial or temporal indication of at least a portion of the enablement protocol.

Abstract: Certain aspects of the present disclosure support a method and apparatus for fast frequency throttling and re-locking in a phase-locked loop (PLL) device. Aspects of the present disclosure present a method and apparatus for operating in an open loop control (OLC) mode of the PLL device for generating a periodic signal. During the OLC mode, clocking of circuitry interfaced with a digitally-controlled oscillator (DCO) of the PLL device can be disabled. A PLL output frequency associated with the periodic signal generated by the DCO can be controlled directly through a digital control word input into the DCO.

Abstract: Many indoor location services do not require precise knowledge of the position of a mobile device, but simply whether a mobile device is within a particular zone of an indoor area. Existing signals in an indoor space may provide enough information to distinguish between different zones of an indoor area, allowing a server to provide indoor location services without requiring the installation of new signal sources in the indoor area.

Abstract: Many indoor location services do not require precise knowledge of the position of a mobile device, but simply whether a mobile device is within a particular zone of an indoor area. Existing signals in an indoor space may provide enough information to distinguish between different zones of an indoor area, allowing a server to provide indoor location services without requiring the installation of new signal sources in the indoor area.

Abstract: A method of producing an ethylenically unsaturated, typically, an ?, ? ethylenically unsaturated carboxylic acid or ester is described. The method comprises the steps of contacting formaldehyde, or a source of formaldehyde, with a carboxylic acid or ester in the presence of a catalyst and optionally in the presence of an alcohol. The catalyst comprises barium phosphate leaf or plate shaped/like crystals, or a source thereof. A catalyst system is also described. The catalyst system comprises a crystalline barium phosphate catalyst and optionally a catalyst support.