Patents by Inventor Ian Davis

Ian Davis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10208064
    Abstract: The present invention provides compounds of Formula (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: February 19, 2019
    Inventors: Alexander Pasternak, Ian Davies, Fa-Xiang Ding, Jinlong Jiang, Shuzhi Dong, Xin Gu, Takao Suzuki, Joseph P. Vacca, Zhifa Pu, Shouning Xu
  • Publication number: 20190050163
    Abstract: A storage system migrates pages of data based on a determination that the page includes snapshot data. Parameters associated with a page (e.g., a page rank) may be updated based on a determination that the page includes snapshot data. A tiering process may subsequently analyze the parameters to determine whether to migrate the page to a different storage tier. A share-write to a page that is referenced by the snapshot volume and a base volume is utilized to migrate pages that include snapshot data.
    Type: Application
    Filed: August 14, 2017
    Publication date: February 14, 2019
    Inventors: Douglas William Dewey, Ian Davies
  • Publication number: 20190018727
    Abstract: A storage system periodically replicates data to another storage system for data backup and protection. The storage system is configured to detect an irregularity potentially causing a fault in the storage system. Such a detected irregularity may a component failure in a storage device, a temperature change in a storage device, etc. In response to the detected irregularity, the storage system increases a replication rate of data to the backup storage system.
    Type: Application
    Filed: July 17, 2017
    Publication date: January 17, 2019
    Inventors: Stephen S. Huh, Ian Davies, Douglas William Dewey
  • Publication number: 20190014017
    Abstract: Disclosed herein are a system, non-transitory computer readable medium, and method for monitoring and replaying packets. A network tap forwards packets from a first network to a second network. At least one node in the first network has the same IP address as a node in the second network. The packets are replayed in the second network.
    Type: Application
    Filed: July 6, 2018
    Publication date: January 10, 2019
    Inventors: Bijoy Paul, Ian Davies
  • Patent number: 10131674
    Abstract: The present invention is directed to a process for preparing Substituted Indole Compounds of Formula (I): wherein R1, R2, R3 and R4 are as defined herein. These indole compounds are useful as synthetic intermediates for making inhibitors of HCV NS5A.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: November 20, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Daniel A. DiRocco, Ian Davies, Feng Peng, Mark McLaughlin, Louis-Charles Campeau, Yingju Xu
  • Patent number: 10110994
    Abstract: A method, apparatus and computer program product enhance audio quality during a voice communication session, such as by enhancing audio quality for a remote participant in a meeting. In a method and for each of two or more microphones of a first device at a first location, a target audio signal is generated that has been steered in a direction of a target audio source in order to provide at least partial isolation from a second audio source in the same environment. The method also produces a filtered audio signal based on the target audio source at least from a respective one of the two or more microphones. The method also includes mixing the filtered audio signal from at least the first device to create an audio output signal associated with an audio playback format and causing the audio output signal to be output by a second device.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: October 23, 2018
    Assignee: NOKIA TECHNOLOGIES OY
    Inventor: Ian Davis
  • Publication number: 20180286371
    Abstract: An article comprises an elastic membrane having a mass element provided thereon the mass element having an asymmetric shape and a resonator structure having a resonance frequency. The elastic membrane is configured to oscillate in response to a sound wave incident thereon, and the asymmetry of the mass element is configured to induce a flapping motion which in combination with the oscillation of the membrane trap vibrational mechanical energy from the sound wave and the resonator structure is configured to absorb at least a part of the incident sound wave. A composite material comprising the article is also disclosed.
    Type: Application
    Filed: March 31, 2017
    Publication date: October 4, 2018
    Applicants: Alcatel-Lucent USA Inc., Alcatel Lucent
    Inventors: Ian Davis, Todd Salamon
  • Publication number: 20180187825
    Abstract: A counterbalance mechanism which applies a balancing force to lift a load. The counterbalance mechanism includes an adjustment arm pivotally attached at first end to a frame and to a spring at a second end. The counterbalance mechanism further includes a travelling arm pivotally attached at a first end to the frame and connected to the spring at a second end. The counterbalance mechanism further includes one or more cables attached at one end to a container securing a load or arms securing the container. A second end of the one or more cables are attached to the travelling member or pass over a pulley attached to the travelling arm. The one or more cables transmit an assisting force to the container for lowering and raising the container. A relative position of the spring, adjustment arm, and travelling arm are adjusted in response to the load acting on the one or more cables to generally offset the load in the container.
    Type: Application
    Filed: February 27, 2018
    Publication date: July 5, 2018
    Inventors: Jonathan Roberts, Clark Davis, Ian Davis, Jonathan George
  • Patent number: 9980564
    Abstract: A storage system and associated method of assembling the storage system. The storage system includes one or more rails for attaching the storage system to a structure. The storage system further includes one or more arms attached to the one or more rails. The storage system further includes a counterbalance mechanism attached to the one or more arms configured to provide a force to assist lifting or lowering a load applied to the one or more lift arms. The storage system further includes a release for engaging the counterbalance mechanism to assist a user in raising or lowering the one or more lift arms.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 29, 2018
    Inventors: Jonathan Roberts, Clark Davis, Ian Davis, Brian D. Owens
  • Patent number: 9926317
    Abstract: The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: March 27, 2018
    Assignee: Merck Sharp Dohme Corp.
    Inventors: Alexander Pasternak, Ian Davies, Fa-Xiang Ding, Jinglong Jiang, Shuzhi Dong, Xin Gu
  • Patent number: 9903526
    Abstract: A force engine operable to counterbalance a load. The force engine includes one or more energy reservoirs operable to store energy. The one or more energy reservoirs are operable to generate a force to balance the load through the displacement in an operating mode. A traveling member is hingedly connected to the one or more energy reservoirs. The force generated by the one or more energy reservoirs is transferred to the load through the traveling member and an associated linkage. A variable member is coupled to the one or more energy reservoirs. In the adjusting mode the variable member is displaced to configure an operating relationship between the one or more energy reservoirs and the traveling member. A release interacts with the variable member to fix a position of the variable member.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: February 27, 2018
    Inventors: Jonathan Roberts, Clark Davis, Ian Davis, Jonathan George
  • Publication number: 20170334926
    Abstract: The present invention is directed to a process for preparing Substituted Indole Compounds of Formula (I): wherein R1, R2, R3 and R4 are as defined herein. These indole compounds are useful as synthetic intermediates for making inhibitors of HCV NS5A.
    Type: Application
    Filed: November 5, 2015
    Publication date: November 23, 2017
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Daniel A . DiRocco, Ian Davies, Feng Peng, Mark McLaughlin, Louis-Charles Campeau, Yingju Xu
  • Publication number: 20170285917
    Abstract: A method includes formatting for display, on a visual screen, an image comprising: (1) a coordinate system, (2) a plurality of distinguishable areas within the coordinate system, each distinguishable area graphically representing a respective formula, and (3) a plurality of data points. The method also includes receiving user input comprising a modification to a particular distinguishable area. In response to receiving the user input, the method includes modifying one or more respective formulas based on the modification to the distinguishable area. For each data point, the method further includes associating the data point with one of the distinguishable areas by determining which of the modified formulas the data point falls within. The method further includes formatting for display a graphical representation of each modified formula. The method additionally includes storing the graphical representation of each modified formula for use as a modified image in future operations.
    Type: Application
    Filed: March 31, 2016
    Publication date: October 5, 2017
    Inventors: Serguei Mankovskii, Ian Davis, Michael Godfrey
  • Patent number: 9765107
    Abstract: The present invention relates to Cyclic Phosphonate Substituted Nucleoside Derivatives of Formula (I): (structure) and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2 and R3 are as defined herein, as well as to compositions and methods of using the Cyclic Phosphonate Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: September 19, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Stephane Bogen, Vinay Girijavallabhan, Quang Truong, Ping Chen, Frank Bennett, Angela Kerekes, Qun Dang, David B. Olsen, Ian Davies
  • Patent number: 9732111
    Abstract: The present invention relates to 2?-Alkynyl Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2, R3 and R4 are as defined herein. The present invention also relates to compositions comprising at least one 2?-Alkynyl Substituted Nucleoside Derivative, and methods of using the 2?-Alkynyl Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
    Type: Grant
    Filed: November 14, 2013
    Date of Patent: August 15, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Frank Bennett, Yuhua Huang, Lingyan Wang, Stephane L. Bogen, Angela D. Kerekes, Vinay M. Girijavallabhan, Gabor Butora, Quang Truong, Ian Davies, Ann E. Weber
  • Publication number: 20170197989
    Abstract: The present invention provides compounds of Formula (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.
    Type: Application
    Filed: July 9, 2015
    Publication date: July 13, 2017
    Inventors: Alexander Pasternak, Ian Davies, Fa-Xiang Ding, Jinlong Jiang, Shuzhi Dong, Xin Gu, Takao Suzuki, Joseph P. Vacca, Zhifa Pu, Shouning Xu
  • Publication number: 20170197964
    Abstract: The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.
    Type: Application
    Filed: July 9, 2015
    Publication date: July 13, 2017
    Inventors: Alexander Pasternak, Ian Davies, Fa-Xiang Ding, Jinglong Jiang, Shuzhi Dong, Xin Gu
  • Patent number: 9457039
    Abstract: 2?-disubstituted substituted nucleoside derivatives of formula (I) and pharmaceutically acceptable salts thereof are disclosed: (1), wherein A is N3 or NH2 and X, Y, R1, R2, R3, R4, R5 and R18 are as defined herein. Compositions comprising at least one 2?-disubstituted nucleoside derivative, and methods of using the 2?-disubstituted nucleoside derivatives for treating or preventing HCV infection in a patient are disclosed.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: October 4, 2016
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Vinay Girijavallabhan, Stephane Bogen, Weidong Pan, Qun Dang, Ian Davies
  • Publication number: 20160122380
    Abstract: The present invention relates to Cyclic Phosphonate Substituted Nucleoside Derivatives of Formula (I): (structure) and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2 and R3 are as defined herein, as well as to compositions and methods of using the Cyclic Phosphonate Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
    Type: Application
    Filed: June 16, 2014
    Publication date: May 5, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Stephane Bogen, Vinay Girijavallabhan, Quang Truong, Ping Chen, Frank Bennett, Angela Kerekes, Qun Dang, David B. Olsen, Ian Davies
  • Publication number: 20160045526
    Abstract: 2?-disubstituted substituted nucleoside derivatives of formula (I) and pharmaceutically acceptable salts thereof are disclosed: (1), wherein A is N3 or NH2 and X, Y, R1, R2, R3, R4, R5 and R18 are as defined herein. Compositions comprising at least one 2?-disubstituted nucleoside derivative, and methods of using the 2?-disubstituted nucleoside derivatives for treating or preventing HCV infection in a patient are disclosed.
    Type: Application
    Filed: October 11, 2013
    Publication date: February 18, 2016
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Vinay Girijavallabhan, Stephane Bogen, Weidong Pan, Qun Dang, Ian Davies