Patents by Inventor Ian Davis

Ian Davis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2?-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
    Patent number: 9156872
    Abstract: The present invention relates to 2?-Azido Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2 and R3 are as defined herein. The present invention also relates to compositions comprising at least one 2?-Azido Substituted Nucleoside Derivative, and methods of using the 2?-Azido Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: October 13, 2015
    Assignee: MERCK SHARP & DOHME CORP.
    Inventors: Vinay Girijavallabhan, F. George Njoroge, Stephane Bogen, Frank Bennett, Vishal Verma, Ashok Arasappan, Kevin Chen, Ying Huang, Angela Kerekes, Latha Nair, Dmitri Pissarnitski, Qun Dang, Ian Davies, David B. Olsen, Andrew Stamford, Joseph P. Vacca
  • 2?-cyano substituted nucleoside derivatives and methods of use thereof useful for the treatment of viral diseases
    Patent number: 9150603
    Abstract: The present invention relates to 2?-Cyano Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2 and R3 are as defined herein. The present invention also relates to compositions comprising at least one 2?-Cyano Substituted Nucleoside Derivative, and methods of using the 2?-Cyano Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: October 6, 2015
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Vinay Girijavallabhan, F. George Njoroge, Stephane Bogen, Angela Kerekes, Frank Bennett, Ying Huang, Latha Nair, Dmitri Pissarnitski, Vishal Verma, Qun Dang, Ian Davies, David B. Olsen, Andrew Stamford, Joseph P. Vacca
  • 2'-CYANO SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
    Publication number: 20150274739
    Abstract: Compounds of Formula (I) are disclosed, wherein R1, R2, R3, R4, R5, and R18 are defined herein. The compounds encompassed by Formula (I) include compounds which are HCV NS5B inhibitors and other compounds which can be metabolized in vivo to HCV NS5B inhibitors. The compounds and their pharmaceutically acceptable salts are useful for the prophylaxis or treatment of infection by HCV and the prophylaxis, treatment, or delay in the onset of disease caused by HCV. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
    Type: Application
    Filed: October 11, 2013
    Publication date: October 1, 2015
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Vinay Girijavallabhan, Stephane Bogen, Weidong Pan, Qun Dang, Ian Davies
  • Systems and methods for processing documents of unknown or unspecified format
    Patent number: 9122898
    Abstract: A computer implemented method for extracting meaningful text from a document of unknown or unspecified format. In a particular embodiment, the method includes reading the document, thereby to extract raw encoded text, analysing the raw encoded text, thereby to identify one or more text chunks, and for a given chunk, performing compression identification analysis to determine whether compression is likely. The method can further include performing a decompression process, performing an encoding identification process thereby to identify a likely character encoding protocol, and converting the chunk using the identified likely character encoding protocol, thereby to output the chunk as readable text.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: September 1, 2015
    Assignee: Lexmark International Technology SA
    Inventors: Scott Coles, Derek Murphy, Ben Truscott, Ian Davies
  • METHOD AND APPARATUS FOR MONITORING A CONDITION OF A METER
    Publication number: 20150233731
    Abstract: A method and apparatus for monitoring the condition of a utility meter by obtaining a temperature value associated with the meter, determining whether the temperature value crosses a threshold, triggering an action if the threshold value is crossed. In another form the temperature can be used as a fault parameter to determine the condition of a utility meter.
    Type: Application
    Filed: July 6, 2012
    Publication date: August 20, 2015
    Inventors: Keith Torpy, Marc Circosta, Marcelo DeMarco, Ian Davis, Paul Collins
  • 2?-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
    Patent number: 9061041
    Abstract: The present invention relates to 2?-Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, R1, R2 and R3 are as defined herein. The present invention also relates to compositions comprising at least one 2?-Substituted Nucleoside Derivative, and methods of using the 2?-Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: June 23, 2015
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Vinay Girijavallabhan, F. George Njoroge, Stephane Bogen, Vishal Verma, Frank Bennett, Angela Kerekes, Ashok Arasappan, Dmitri Pissarnitski, Qun Dang, Ian Davies, David B. Olsen, Andrew Stamford, Joseph P. Vacca
  • REGULATORY POLYNUCLEOTIDES AND USES THEREOF
    Publication number: 20150033407
    Abstract: The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided.
    Type: Application
    Filed: June 27, 2014
    Publication date: January 29, 2015
    Inventors: Tedd D. Elich, Philip N. Benfey, Ai-Jiuan Wu, David A. Orlando, Ian Davis
  • REGULATORY POLYNUCLEOTIDES AND USES THEREOF
    Publication number: 20140331358
    Abstract: The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided.
    Type: Application
    Filed: April 9, 2014
    Publication date: November 6, 2014
    Applicant: Monsanto Technology LLC
    Inventors: Tedd D. Elich, Philip N. Benfey, Ai-Jiuan Wu, David A. Orlando, Ian Davis
  • SYSTEM AND METHOD FOR ASSEMBLING AND USING ASSISTED STORAGE
    Publication number: 20140263122
    Abstract: A storage system and associated method of assembling the storage system. The storage system includes one or more rails for attaching the storage system to a structure. The storage system further includes one or more arms attached to the one or more rails. The storage system further includes a counterbalance mechanism attached to the one or more arms configured to provide a force to assist lifting or lowering a load applied to the one or more lift arms. The storage system further includes a release for engaging the counterbalance mechanism to assist a user in raising or lowering the one or more lift arms.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Inventors: Jonathan Roberts, Clark Davis, Ian Davis, Brian D. Owens
  • COUNTERBALANCE SYSTEM FOR ASSISTING A USER
    Publication number: 20140260735
    Abstract: A counterbalance system and lifting system for assisting a user. The system includes one or more arms, such as lift arms, that by user input from a user may be operated to raise and lower a load carried by a tray. The system further includes a counterbalance mechanism connected to the one or more arms configured to assist raising and lowering the loaded tray. The counterbalance mechanism may be configured to adjust to a force provided by the counterbalance system in response to the load changing. The system further includes a release for engaging the counterbalance mechanism to assist the user in raising or lowering the tray.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Inventors: Jonathan Roberts, Clark Davis, Ian Davis, Brian D. Owens
  • Regulatory polynucleotides and uses thereof
    Patent number: 8816152
    Abstract: The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided.
    Type: Grant
    Filed: June 20, 2012
    Date of Patent: August 26, 2014
    Assignee: Monsanto Technology LLC
    Inventors: Tedd D. Elich, Philip N. Benfey, Ai-Jiuan Wu, David A. Orlando, Ian Davis
  • REGULATORY POLYNUCLEOTIDES AND USES THEREOF
    Publication number: 20140237682
    Abstract: The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided.
    Type: Application
    Filed: July 18, 2012
    Publication date: August 21, 2014
    Inventors: Tedd D. Elich, Philip N. Benfey, Ian Davis
  • REGULATORY POLYNUCLEOTIDES AND USES THEREOF
    Publication number: 20140230093
    Abstract: The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided.
    Type: Application
    Filed: July 18, 2012
    Publication date: August 14, 2014
    Inventors: Tedd D. Elich, Philip N. Benfey, Ian Davis, David A. Orlando
  • 2'-AZIDO SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
    Publication number: 20140206640
    Abstract: The present invention relates to 2?-Azido Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2 and R3 are as defined herein. The present invention also relates to compositions comprising at least one 2?-Azido Substituted Nucleoside Derivative, and methods of using the 2?-Azido Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
    Type: Application
    Filed: April 11, 2012
    Publication date: July 24, 2014
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Vinay Girijavallabhan, F. George Njoroge, Stephane Bogen, Frank Bennett, Vishal Verma, Ashok Arasappan, Kevin X. Chen, Ying Huang, Angela Kerekes, Latha Nair, Dimitri Pissarnitski, Qun Dang, Ian Davies, David B. Olsen, Andrew Stamford, Joseph P. Vacca
  • 2'-CYANO SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF USEFUL FOR THE TREATMENT OF VIRAL DISEASES
    Publication number: 20140161770
    Abstract: The present invention relates to 2?-Cyano Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2 and R3 are as defined herein. The present invention also relates to compositions comprising at least one 2?-Cyano Substituted Nucleoside Derivative, and methods of using the 2?-Cyano Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
    Type: Application
    Filed: April 11, 2012
    Publication date: June 12, 2014
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Vinay Girijavallabhan, F. George Njoroge, Stephane Bogen, Angela Kerekes, Frank Bennett, Ying Huang, Latha Nair, Dmitri Pissarnitski, Vishal Verma, Qun Dang, Ian Davies, David B. Olsen, Andrew Stamford, Joseph P. Vacca
  • 2'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
    Publication number: 20140154211
    Abstract: The present invention relates to 2?-Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, R1, R2 and R3 are as defined herein. The present invention also relates to compositions comprising at least one 2?-Substituted Nucleoside Derivative, and methods of using the 2?-Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
    Type: Application
    Filed: April 11, 2012
    Publication date: June 5, 2014
    Inventors: Vinay Girijavallabhan, F. George Njoroge, Stephane Bogen, Vishal Verma, Frank Bennett, Angela Kereles, Ashok Arasappan, Dmitri Pissarnitski, Qun Dang, Ian Davies, David B. Olsen, Andrew Stamford, Joseph P. Vacca
  • SYSTEM AND APPARATUS FOR LOCATING FAULTS IN A CABLE NETWORK
    Publication number: 20140146866
    Abstract: A range to fault (RTF) module (100) for use in a system for locating faults in a cable network is discussed. The module includes an input port (101) for coupling the module to a PIM analyser. The module (100) also includes an output port (102) for connection to the device under test (DUT). In addition to the input (101) and output (102) ports the module is provided with a monitor port (103) for receipt of a PIM signal from the PIM analyser. The module in this instance also includes two USB ports (104a), (104b) enabling a serial connection between the PIM analyser and the module (100).
    Type: Application
    Filed: March 21, 2012
    Publication date: May 29, 2014
    Inventors: Frank Strachan, Brendan Horsfield, Greg Delforce, Ian Davies
  • 2'-METHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
    Publication number: 20140128339
    Abstract: The present invention relates to 2?-Methyl Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein R, R1, R2 and R3, are as defined herein. The present invention also relates to compositions comprising at least one 2?-Methyl Substituted Nucleoside Derivative, and methods of using the 2?-Methyl Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
    Type: Application
    Filed: October 15, 2013
    Publication date: May 8, 2014
    Inventors: Vinay Girijavallabhan, Stephane Bogen, Quang T. Truong, Ping Chen, Angela Kerekes, Frank Bennett, Sara Esposite, Qingmei Hong, Ian Davies
  • Expression of FoxP3 by cancer cells
    Patent number: 8420791
    Abstract: The present invention relates to the treatment, diagnosis, and prophylaxis of cancer based on the expression of foxp3.
    Type: Grant
    Filed: November 27, 2007
    Date of Patent: April 16, 2013
    Assignee: Ludwig Institute for Cancer Research Ltd.
    Inventors: Lisa Michelle Ebert, Weisan Chen, Jonathan S. Cebon, Ian Davis
  • SYSTEMS AND METHODS FOR PROCESSING DOCUMENTS OF UNKNOWN OR UNSPECIFIED FORMAT
    Publication number: 20130077855
    Abstract: A computer implemented method for extracting meaningful text from a document of unknown or unspecified format. In a particular embodiment, the method includes reading the document, thereby to extract raw encoded text, analysing the raw encoded text, thereby to identify one or more text chunks, and for a given chunk, performing compression identification analysis to determine whether compression is likely and, in the event that compression. The method can further include performing a decompression process, performing an encoding identification process thereby to identify a likely character encoding protocol, and converting the chunk using the identified likely character encoding protocol, thereby to output the chunk as readable text.
    Type: Application
    Filed: March 22, 2012
    Publication date: March 28, 2013
    Applicant: ISYS Search Software Pty Ltd.
    Inventors: Scott Coles, Derek Murphy, Ben Truscott, Ian Davies