Abstract: A slot milling sequence includes a plurality of material removal processes or operations. Each of the material removal operations includes utilization of an end mill tool. Some of the material removal operations utilize trochoidal tool paths, whereas other material removal processes utilize one or more profile cuts. Some material removal operations that utilize profile cuts remove material from both sides of the cut in a single pass, whereas other material removal operations remove material from one side of the cut via a first pass of the end mill tool and remove material from the opposing side of the cut via a second pass of the end mill tool.

Abstract: Spray-dried metal-organic frameworks (MOFs) comprising therapeutic and/or diagnostic metal ions and therapeutic and/or diagnostic organic ligands are described. Both the metal ion and organic ligand can have activity related to the treatment and/or diagnosis of a pulmonary disease or disorder, such as tuberculosis, or another disease related to a pulmonary infection. The MOFs can be adminstered to subjects via inhalation (e.g., as aerosols). Methods of treating and diagnosing pulmonary diseases or disorders are also described.

Abstract: An example method of entity lifecycle management in a service monitoring system includes: receiving, by a software application of a service monitoring system, a policy definition specifying an entity lifecycle management policy, wherein the entity lifecycle management policy defines management rules for a plurality of entities in the network environment, wherein each entity of the plurality of entities is represented by one of: a device, an application, a service, or a user account; identifying, by applying the entity lifecycle management policy to a plurality of active entities, one or more candidate entities for retirement; retiring at least a subset of the one or more candidate entities; and excluding the retired entities from the plurality of active entities, thus preventing the retired entities from interacting with other components of the service monitoring system.

Abstract: A composite charge is formed between two compression dies into a composite laminate stiffener. The stiffener is contoured along its length by contouring the dies. Wrinkle diffusers attached to, or embedded or incorporated into the tool surfaces of the dies, diffuse wrinkles formed on the inside radius of the stiffener during the contouring.

Abstract: The present invention relates to the real-time simulation of sound in three-dimensional virtual environments. In particular, a geometric method based on the principles of acoustic radiosity determines the room impulse responses of a virtual environment with arbitrary polygonal surfaces. The complexity of the method is of the order of the square of the number of patches that define the virtual environment. The room impulse responses are convolved with an audio signal and output through a speaker to simulate reverberation within the virtual environment, which corresponds to a physical environment.

Abstract: Described embodiments generally relate to a hydrocyclone for isolating particles within a fluid. The hydrocyclone comprises an upper conical section defining at least one inlet to receive the fluid, a vortex finder extending into the upper conical section, and an overflow port fluidly connected to the vortex finder and configured to expel a portion of the fluid out of the upper conical section; and a lower conical section defining an underflow port to expel the remaining fluid out of the lower conical section, the lower conical section being fluidly connected to the upper conical section to define a single hollow volume. The shape of the hydrocyclone causes particles smaller than a predetermined size to be isolated by expelling the particles from the overflow port.

Abstract: Devices, systems, and methods herein relate to cooling a head of a patient. These systems and methods may comprise a cooling cap assembly comprising a heat exchanger configured to be wrapped around a head of a patient and a compression assembly releasably coupled to the heat exchanger. The compression assembly may comprise an enclosure and an inflatable member coupled to an internal surface of the enclosure. When coupled, the inflatable member may be positioned between the enclosure and the heat exchanger. The heat exchanger may be separate from and moveable relative to the inflatable member.

Abstract: An MRI scanner and a method for operation of the MRI scanner are provided. The MRI scanner has a first receiving antenna for receiving a magnetic resonance signal from a patient in a patient tunnel, a second receiving antenna for receiving a signal having the Larmor frequency of the magnetic resonance signal, and a receiver. The second receiving antenna is located outside of the patient tunnel or near an opening thereof. The receiver has a signal connection to the first receiving antenna and the second receiving antenna and is configured to suppress an interference signal by the second receiving antenna in the magnetic resonance signal received by the first receiving antenna.

Abstract: Systems and methods are described for performing adaptive thresholding on key performance indicator (KPI) values using an online machine learning algorithm as the KPI values or the data from which the KPI values are derived is being ingested. For example, the system can identify outliers in a moving window of KPI values. To implement the adaptive thresholding, the system may identify seasonality and/or trend components in historical KPI values. When a new KPI value is obtained, the system may remove the identified seasonality and/or trend components from the KPI value, and determine whether the modified KPI value is an outlier using sketches or quantiles. The system can then repeat this process for each subsequently received KPI value.

Abstract: A composite charge is formed between two compression dies into a composite laminate stiffener. The stiffener is contoured along its length by contouring the dies. Wrinkle diffusers attached to, or embedded or incorporated into the tool surfaces of the dies, diffuse wrinkles formed on the inside radius of the stiffener during the contouring.

Abstract: Composite assemblies are described that include composite spars that are co-cured with one or more sacrificial members on their flanges, forming an integrated sacrificial surface for the composite spars. In one embodiment, the composite assembly includes a composite spar having a web and flanges that project from sides of the web. The composite assembly further includes a sacrificial member of composite materials co-cured with the composite spar on an outer surface of at least one of the flanges. In addition, the sacrificial member has an outer surface that has been machined into conformance with an inner surface of at least one skin panel for an aircraft structure to form a contact surface with the at least one skin panel.

Abstract: An example method of entity lifecycle management in a service monitoring system includes: receiving, by a software application of a service monitoring system, a policy definition specifying an entity lifecycle management policy, wherein the entity lifecycle management policy defines management rules for a plurality of entities in the network environment, wherein each entity of the plurality of entities is represented by one of: a device, an application, a service, or a user account; identifying, by applying the entity lifecycle management policy to a plurality of active entities, one or more candidate entities for retirement; identifying, as retired entities, at least a subset of the one or more candidate entities; and excluding the retired entities from the plurality of active entities, thus preventing the retired entities from interacting with other components of the service monitoring system.

Abstract: Devices, systems, and methods herein relate to cooling a head of a patient. These systems and methods may comprise a cooling cap assembly comprising a heat exchanger configured to be wrapped around a head of a patient and a compression assembly releasably coupled to the heat exchanger. The compression assembly may comprise an enclosure and an inflatable member coupled to an internal surface of the enclosure. When coupled, the inflatable member may be positioned between the enclosure and the heat exchanger. The heat exchanger may be separate from and moveable relative to the inflatable member.

Abstract: Laser light is coupled to optical fibers arranged in a sheet, which may be in the form of netting, mesh or fabric. Scattering centers or bends in the optical fibers allow the coupled light to escape from the sides of the fibers. Depending on the selection of wavelengths for the lasers, the resulting luminous sheet may be used for illumination of crops grown in vertical farms. The laser wavelengths excite plant photopigments for predetermined physiological responses, and the light source intensities may be temporally modulated to maximize photosynthesis and control photomorphogenesis responses. Each laser may be independently controlled, and at least one laser may emit ultraviolet-C radiation. The luminous sheet may be used for purification of air flowing through an air duct.

Abstract: The present disclosure relates to delivery and release compositions, systems, and methods of use thereof. In particular, the present disclosure relates to degradable polymeric systems including a first epoxy-containing monomer and a second, different epoxy-containing monomer, wherein the degradable polymeric system is crosslinked, and wherein one of the first epoxy-containing monomer and the second, different epoxy-containing monomer includes one or more ester groups; delivery systems incorporating degradable polymeric systems; and methods for providing cargo to a petroleum reservoir.

Abstract: Given the complexity of architectural spaces and the need to calculate spherical irradiances, it is difficult to determine how much ultraviolet radiation is necessary to adequately kill airborne pathogens. An interior environment with luminaires is modeled. Spherical irradiance meters are positioned in the model and the direct and indirect spherical irradiance is calculated for each sensor. From this, an irradiance field is interpolated for a volume of interest, and using known fluence response values for killing pathogens, a reduction in the pathogens is predicted. Based on the predicted reduction, spaces are built accordingly, and ultraviolet luminaires are installed and controlled.

Abstract: A seal arrangement is provided for sealing an exposed edge of a composite laminate part having a fay surface configured to be joined to a structure. The seal arrangement includes a precured edge seal covering the exposed edge and a cover covering the edge seal. A seal bead located within a recess in the fay surface of the part forms a seal between the part and the structure.

Abstract: The present disclosure relates generally to methods and adeno-associated virus (AAV) vectors for in vivo transduction. The disclosure is directed to methods for producing modified AAV capsid polypeptides and AAV vectors that are suitable for transduction of cells in vivo, and methods for screening AAV vectors. The disclosure also relates to adeno-associated virus (AAV) capsid polypeptides and encoding nucleic acid molecules, AAV vectors comprising the capsid polypeptides, and nucleic acid vectors comprising the encoding nucleic acids molecules, as well as to host cells comprising the vectors. The disclosure also relates to methods and uses of the polypeptides, encoding nucleic acids molecules, vectors and host cells.

Abstract: A slot milling sequence includes a plurality of material removal processes or operations. Each of the material removal operations includes utilization of an end mill tool. Some of the material removal operations utilize trochoidal tool paths, whereas other material removal processes utilize one or more profile cuts. Some material removal operations that utilize profile cuts remove material from both sides of the cut in a single pass, whereas other material removal operations remove material from one side of the cut via a first pass of the end mill tool and remove material from the opposing side of the cut via a second pass of the end mill tool.

Abstract: A biological lighting system to provide temporally- and spatially-modulated photon flux output and spectral power distributions to plants on a circadian and circannual basis, or circadian and life cycle basis, to maximize effective and efficient growth in a horticultural setting. The photon flux or irradiance output and the spectral power distribution are modulated to match circadian and circannual rhythms, with individual or multiple luminaires controlled through one or more controllers. Different lighting spectra can be employed depending on the direction of illumination. The photon flux or irradiance output and the spectral power distribution may be set as best suited for any particular plant species, and the system is also useful for raising animals.