Abstract: A light bulb includes a base; a light guide having opposed major surfaces between which light propagates by total internal reflection, a light input edge, and two light output regions of different optical characteristics at least one of which is associated with a corresponding one of the major surfaces; and a light source electrically coupled to the base and located adjacent the light input edge. The light source and the light guide are variably positionable relative to one another to vary a location on the light input edge at which light is input to the light guide such that light is emitted from the light guide selectively apportioned between the light output regions so that a characteristic of the light output from the light bulb is modified based on the optical characteristics associated with the light output regions and the relative positioning of the light source and the light guide.

Abstract: A light bulb includes a base, light guide, and light source. The base is configured to mechanically mount the light bulb and receive electrical power. The light guide includes light input regions, at least one of the light input regions associated with an optical modifying characteristic, the light guide configured to propagate light by total internal reflection. The light source is located adjacent the light input regions. The light source and light input regions are variably positionable relative to one another to vary location at which light is incident on the light input regions such that light emitted from the light source is selectively apportioned between the light input regions. A characteristic of the light output from the light bulb is modified based on the optical modifying characteristic of the at least one of the light input regions and the relative positioning of the light source and light input regions.

Abstract: A lighting assembly includes a light guide to propagate light by total internal reflection and having a light output region on a major surface thereof. The lighting assembly also includes an optical adjuster having a major surface juxtaposed with and conforming to the light guide's major surface. The optical adjuster has a first region and a second region, the first region having a light modifying characteristic. The optical adjuster and light output region are variably positionable relative to one another to selectively apportion light emitted from the light output region between the first region and the second region. In this way, light apportioned to the first region is modified by the light modifying characteristic so that light output from the lighting assembly is modified based on relative positioning of the optical adjuster and the light guide.

Abstract: A light source includes a light emitting device that emits light, and a spectrum adjuster that is positionable relative a light path of the light emitted by the light emitting device. The spectrum adjuster includes a region of continuously-variable spectrum adjusting material, usable for adjusting the spectrum of light passing through the spectrum adjuster. The variable spectrum adjusting material may be color-attenuating material, such as a filtering material, or may be wavelength-shifting material, such as a phosphor. The light source has adjustable spectrum of its output light depending upon the relative positioning of the light emitting device and the spectrum adjuster.

Abstract: A method and a system for displaying images are provided. In the method, a pixel is provided that includes a layer of ferroelectric material and a layer of liquid crystal material. A first electric field is momentarily applied to the pixel to electrically polarize the ferroelectric layer to a first polarization. The first polarization is then used to maintain the liquid crystal material in a first orientation corresponding to a first apparent brightness of the pixel.

Abstract: A method and a system for displaying images are provided. In the method, a pixel is provided that includes a layer of ferroelectric material and a layer of liquid crystal material. A first electric field is momentarily applied to the pixel to electrically polarize the ferroelectric layer to a first polarization. The first polarization is then used to maintain the liquid crystal material in a first orientation corresponding to a first apparent brightness of the pixel.

Abstract: The pen input device has both a movement detection system and a position detection system that collectively track the position of the pen input device during a writing operation on a writing surface. The pen input device has a writing tip capable of performing a writing operation in contact with the writing surface. A controller is operable to activate the movement detection system continuously during the writing operation and to activate the position detection system intermittently during the writing operation. The movement detection system is operable to determine movement data that represent changes between successive positions of the writing tip. The position detection system is operable to determine position data that represents a position of the writing tip on the writing surface.

Abstract: Embodiments of the acoustic galvanic isolator comprise a carrier signal source, a modulator connected to receive an information signal and the carrier signal, a demodulator, and an electrically-isolating acoustic coupler connected between the modulator and the demodulator. The electrically-isolating acoustic coupler comprises series-connected decoupled stacked bulk acoustic resonators (DSBARs).

Abstract: Embodiments of the acoustic galvanic isolator comprise a carrier signal source, a modulator connected to receive an information signal and the carrier signal, a demodulator, and, connected between the modulator and the demodulator, an electrically-isolating acoustic coupler comprising an electrically-isolating film acoustically-coupled transformer (FACT).

Abstract: A multiple analyte detection system includes a carrier having reagents disposed thereat, with each of the reagents capable of optically changing in response to exposure to a respective analyte. The system further includes a photodetector positioned to collectively detect light interacted with each of the reagents, a processor to determine a presence or an absence of each of the analytes in response to the light collectively-detected, and an indicator to provide an indication of the presence or the absence of each of the analytes. A method of detecting multiple analytes includes exposing reagents capable of optically changing in response to exposure to a respective analyte to a sample. The method further includes collectively detecting light interacted with each of the reagents, determining a presence or an absence of each of the analytes in response to the light collectively detected, and indicating the presence or the absence of each of the analytes determined.

Abstract: An optoelectronic system for measuring fluorescence or luminescence emission decay, including (a) a light source being a light emitting diode, a semiconductor laser or a flash tube; (b) a first integrated circuit comprising at least one circuit causing the light source to emit light pulses towards a sample which causes a fluorescence or luminescence emission from the sample; (c) a photodiode detecting the emission; (d) a second integrated circuit comprising a detection analysis system determining information about the sample by analyzing decay of the detected emission; and (e) an enclosure enclosing the light source, the first integrated circuit, the second integrated circuit and the photodiode.

Abstract: The optically-switched optical network comprises information signal channels allocated for optically transmitting one or more information signals; routing signal channels allocated for optically transmitting routing signals in parallel with the information signals; and switching nodes each operable in responsive to at least one of the routing signals to switch a multi-wavelength optical signal comprising the one or more information signals and the routing signals to another of the switching nodes.

Abstract: A diagnostic assay reader includes a detector configured to read a diagnostic assay result and develop a result signal that is indicative of the result, a processor configured to process the result signal, and an external power interface connected to the detector and to the processor, the external power interface configured to receive external power for the diagnostic assay reader.

Abstract: A method and a system for displaying images are provided. In the method, a pixel is provided that includes a layer of ferroelectric material and a layer of liquid crystal material. A first electric field is momentarily applied to the pixel to electrically polarize the ferroelectric layer to a first polarization. The first polarization is then used to maintain the liquid crystal material in a first orientation corresponding to a first apparent brightness of the pixel.

Abstract: A spatial pressure distribution sensor comprises a sensor array and a processor. The sensor array comprises an array of pressure sensors. Each of the pressure sensors is operable to generate a respective pressure signal in response to pressure applied to it. The pressure signal quantifies the pressure with greater than single-bit resolution. The processor is operable in response to the pressure signals to generate an information signal representing the spatial distribution of pressure applied to the sensor array.

Abstract: An apparatus for generating navigation information indicative of translational movement of a stylus including a ball rotatably mounted at an end of the stylus, a sensor system and a processor. The ball has an orientation-indicating property and the sensor system is arranged to sense the orientation-indicating property of the ball. The processor is coupled to the sensor system. In response to successive sensings of the orientation-indicating property, the processor is operable to determine changes in the orientation of the ball and to derive the navigation information from the orientation changes.

Abstract: The multi-channel optical transmitter is composed of a tunable optical signal source, an optical multiplexer and an intensity reducer. The tunable optical signal source includes a tunable laser, and additionally includes an optical signal output through which it outputs an optical signal to one of the inputs of the optical multiplexer. The intensity reducer is for reducing the intensity of the optical signal output by the optical signal source during tuning of the tunable laser. The intensity reducer prevents the tunable optical signal source from injecting high levels of noise into the channels during tuning of the tunable optical signal source.

Abstract: A method and a system for displaying images are provided. In the method, a pixel is provided that includes a layer of ferroelectric material and a layer of liquid crystal material. A first electric field is momentarily applied to the pixel to electrically polarize the ferroelectric layer to a first polarization. The first polarization is then used to maintain the liquid crystal material in a first orientation corresponding to a first apparent brightness of the pixel.

Abstract: The invention relates to the use of compounds of formula (I) and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, in the preparation of a medicament for inhibiting the activity of DNA-PK, wherein R1 and R2 are independently hydrogen, an optionally substituted C1-7 alkyl group, C3-20 heterocyclyl group, or C5-20 aryl group, or may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; X and Y are selected from CR4 and O, O and CR?4 and NR?4 and N, where the unsaturation is in the appropriate place in the ring, and where one of R3 and R4 or R?4 is an optionally substituted C3-20 heteroaryl or C5-20 aryl group, and the other of R3 and R4 or R?4 is H, or R3 and R4 or R?4 together are -A-B—, which collectively represent a fused optionally substituted aromatic ring. The compounds also selectively inhibit the activity of DNA-PK compared to PI 3-kinase and/or ATM.

Abstract: A compound of formula I: and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, wherein: R1 and R2 are independently selected from hydrogen, an optionally substituted C1-7 alkyl group, C3-20heterocyclyl group, or C5-20 aryl group, or may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; Q is —NH—C(?O)— or —O—; Y is an optionally substituted C1-5 alkylene group; X is selected from SR3 or NR4R5, wherein, R3 or R4 and R5 are independently selected from hydrogen, optionally substituted C1-7 alkyl, C5-20 aryl, or C3-20 heterocyclyl groups, or R4 and R5 may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; if Q is —O—, X is additionally selected from —C(?O)—NR6R7, wherein R6 and R7 are independently selected from hydrogen, optionally substituted C1-7 alkyl, C5-20 aryl, or C3-20 heterocyclyl groups, o