Abstract: A spatial pressure distribution sensor comprises a sensor array and a processor. The sensor array comprises an array of pressure sensors. Each of the pressure sensors is operable to generate a respective pressure signal in response to pressure applied to it. The pressure signal quantifies the pressure with greater than single-bit resolution. The processor is operable in response to the pressure signals to generate an information signal representing the spatial distribution of pressure applied to the sensor array.

Abstract: Embodiments of the acoustic galvanic isolator comprise a carrier signal source, a modulator connected to receive an information signal and the carrier signal, a demodulator, and an electrically-isolating acoustic coupler connected between the modulator and the demodulator. The electrically-isolating acoustic coupler comprises series-connected decoupled stacked bulk acoustic resonators (DSBARs).

Abstract: Embodiments of the acoustic galvanic isolator comprise a carrier signal source, a modulator connected to receive an information signal and the carrier signal, a demodulator, and an electrically-isolating acoustic coupler connected between the modulator and the demodulator. In an exemplary embodiment, the electrically-isolating acoustic coupler comprises film bulk acoustic resonators (FBARs). An electrically-isolating acoustic coupler is physically small and is inexpensive to fabricate yet is capable of passing information signals having data rates in excess of 100 Mbit/s and has a substantial breakdown voltage between its inputs and its outputs.

Abstract: Embodiments of the acoustic galvanic isolator comprise a carrier signal source, a modulator connected to receive an information signal and the carrier signal, a demodulator, and, connected between the modulator and the demodulator, an electrically-isolating acoustic coupler comprising an electrically-isolating film acoustically-coupled transformer (FACT).

Abstract: Compounds of formula I: wherein A, B and D are respectively selected from the group consisting of: (i) CH, NH, C; (ii) CH, N, N;and (iii) CH, O, C; the dotted lines represent two double bonds in the appropriate locations; and where Z is selected from S, O, C(?O), CH2 and NH are disclosed for use in inhibiting DNA-PK.

Abstract: Compounds of formula l: wherein A, B and D are respectively selected from the group consisting of: (i) CH, NH, C; (ii) CH, N, N;and (iii) CH, O, C; are disclosed for use in inhibiting DNA-PK.

Abstract: The network comprises topographic network devices and communication links interconnecting the topographic network devices. The topographic network devices each have a physical location represented by a topographic coordinate set, and a network address that includes the topographic coordinate set. A message configured for transmission through the network includes a destination coordinate set, which is the topographic coordinate set of a destination network device that is one of the topographic network devices. A topographic network device comprises channels, a coordinate store and a topographic processor. The channels are each configured for connection via a communication link to another of the topographic network devices. The channels include a first channel via which the message is received. The coordinate store stores connected device coordinate sets, which are the topographic coordinate sets of the topographic network devices to which the channels are directly connected.

Abstract: The pen input device has both a movement detection system and a position detection system that collectively track the position of the pen input device during a writing operation on a writing surface. The pen input device has a writing tip capable of performing a writing operation in contact with the writing surface. A controller is operable to activate the movement detection system continuously during the writing operation and to activate the position detection system intermittently during the writing operation. The movement detection system is operable to determine movement data that represent changes between successive positions of the writing tip. The position detection system is operable to determine position data that represents a position of the writing tip on the writing surface.

Abstract: The optical fiber-based communication system comprises a distribution optical fiber that extends proximately to a plurality of end users, and tap-off modules coupled to the distribution optical fiber at intervals along its length. Each of the tap-off modules includes a port in optical communication with the distribution optical fiber. The optical fiber-based communication system additionally comprises a branch optical fiber connected to the port of each of at least some of the tap-off modules and that extends to a corresponding one of the end users.

Abstract: Methods, machines, and machine-readable media storing machine-readable instructions for automatically scheduling meetings are described. In one aspect, a meeting request is received. The meeting request specifies a meeting duration, a set of non-fungible resources, and a number of required fungible resources of a specified type. A potential-meeting-time set of timeslots is determined. The potential-meeting-time set corresponding to a union of a first set of timeslots during each of which at least some of the non-fungible resources are available and a second set of timeslots corresponding to an intersection of each timeslot during which at least the specified number of fungible resources of the specified type are available. At least one timeslot having a duration at least as long as the specified meeting duration is identified in the potential-meeting-time set.

Abstract: A method of reading an assay includes illuminating a substrate. The substrate includes a sensitive region. The method also includes detecting whether the substrate was exposed to an analyte of interest. The detecting includes using low resolution detection and a priori data about the sensitive region to determine whether a characteristic of a first portion of the illumination returned from the sensitive region differs from a characteristic of a second portion of the illumination returned from the substrate outside the sensitive region.

Abstract: An optoelectronic system for measuring fluorescence or luminescence emission decay, including (a) a light source being a light emitting diode, a semiconductor laser or a flash tube; (b) a first integrated circuit comprising at least one circuit causing the light source to emit light pulses towards a sample which causes a fluorescence or luminescence emission from the sample; (c) a photodiode detecting the emission; (d) a second integrated circuit comprising a detection analysis system determining information about the sample by analyzing decay of the detected emission; and (e) an enclosure enclosing the light source, the first integrated circuit, the second integrated circuit and the photodiode.

Abstract: A compound of formula I: and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, wherein: R1 and R2 are independently selected from hydrogen, an optionally substituted C1-7 alkyl group, C3-20 heterocyclyl group, or C5-20 aryl group, or may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; Q is —NH—C(?O)— or —O—; Y is an optionally substituted C1-5 alkylene group; X is selected from SR3 or NR4R5, wherein, R3, or R4 and R5 are independently selected from hydrogen, optionally substituted C1-7 alkyl, C5-20 aryl, or C3-20 heterocyclyl groups, or R4 and R5 may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; if Q is —O—, X is additionally selected from —C(?O)—NR6R7, wherein R6 and R7 are independently selected from hydrogen, optionally substituted C1-7 alkyl, C5-20 aryl, or C3-20 heterocyclyl g

Abstract: A network for communicating a message is established by providing a network that includes topographic network devices and communication links interconnecting the topographic network devices. The topographic network devices each have a physical location represented by a topographic coordinate set. A network address is assigned to each of the topographic network devices. The network address includes the topographic coordinate set of the topographic network device. The topographic coordinate set of the topographic network device is transmitted to those of the topographic network devices directly connected to the topographic network device. The topographic coordinate set of the topographic network device is received and stored at at least one of the topographic network devices directly connected to the topographic network device.

Abstract: The tunable optical filter includes an elastic substrate, a diffractive element in the elastic substrate, an actuator for stretching the elastic substrate to control the pitch of the diffractive element, a first optical path and a second optical path. The diffractive element optically couples the second optical path to the first optical path at an optical frequency determined by the pitch of the diffractive element.

Abstract: The optical receiver comprises an optical input path, a light detector array, an optical converging element and an information signal generator. The light detector array includes light detectors and a light-sensitive surface. Each light detector generates an electrical signal in response to light. The optical converging element is located to focus an optical input signal received via the optical input path to form a spot on the light-sensitive surface of the light detector array. The spot has an area less than the area of the light-sensitive surface but greater than the area of one of the light detectors. The information signal generator generates an electrical information signal from at least one of the electrical signals. In an embodiment, the information signal generator includes a summer that sums the electrical signals generated by the light detectors to generate the electrical information signal.

Abstract: The network monitoring system comprises a network router with built-in monitoring data gathering. The network router includes channels through which data pass in packets. Each of the packets includes a packet header. The network router additionally includes a header copier and a packet generator. The header copier generates a header copy from the packet header of at least some of the packets. The packet generator receives the header copies and forms monitoring data packets from them. Each monitoring data packet additionally represents temporal data relating to the header copies included in it. A method of obtaining performance data relating to a data transmission network that includes a node passes data through the node in packets. Each of the packets includes a packet header. At least some of the packet headers are copied to obtain respective header copies as monitoring data from which monitoring data packets are formed.

Abstract: The optically-switched optical network comprises information signal channels allocated for optically transmitting one or more information signals; routing signal channels allocated for optically transmitting routing signals in parallel with the information signals; and switching nodes each operable in responsive to at least one of the routing signals to switch a multi-wavelength optical signal comprising the one or more information signals and the routing signals to another of the switching nodes.

Abstract: The external cavity laser includes a resonant cavity defined at one end by a Bragg reflector and a gain medium located in the optical cavity. Coupled to the Bragg reflector is an actuator that changes the pitch of the Bragg reflector and, hence, the wavelength at which the optical cavity is resonant. The wavelength of the light generated by the external cavity laser can therefore be tuned by a single control signal applied to the actuator.

Abstract: The present invention provides compounds of formula (I) and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, wherein R1 and R2 are independently hydrogen, an option ally substituted C1-7 alkyl group, C3-20 heterocyclyl group, or C5-20 aryl group, or may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; and R3 is an optionally substituted C3-20 heterocyclyl or C5-20 aryl group, and their use as pharmaceuticals, particularly in treating diseases which are retroviral mediated or ameliorated by the inhibition of DNA-PK,