Abstract: A ball bat includes a barrel in which one or more stiffening elements are located. The stiffening element may be positioned at a variety of locations, and may have a variety of configurations, for selectively limiting the barrel's performance without appreciably increasing the bat's moment of inertia. In one configuration, the stiffening element includes two radially outer flanges, a radially inner flange, and two web members connecting the outer flanges to the inner flange. The radially outer surfaces of the radially outer flanges contact, and may be affixed to, the inner surface of the barrel wall.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract: The present invention provides pharmaceutically active pyrrolo[2,3-d]pyrimidinyl and pyrrolo[2,3-d]pyridinyl acrylamides and analogues thereof. Such compounds are useful for inhibiting Janus Kinase (JAK). This invention also is directed to compositions comprising methods for making such compounds, and methods for treating and preventing conditions mediated by JAK.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract: A ball bat includes a barrel in which one or more stiffening elements or damping elements, or both, are located. The stiffening or damping elements may be positioned at a variety of locations, and may have a variety of configurations, for selectively reducing the barrel's performance without appreciably increasing the bat's moment of inertia.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract: A sporting-good implement, such as a ball bat or a lacrosse stick, includes a first handle section rotatably connected to a second handle section. The second handle section may be attached to or integral with a tapered region or barrel region of a ball bat, or with a shaft section or head of a lacrosse stick, or with another sporting-good feature. This rotatable engagement allows the relative position of the user's hands to change during the course of a swing, shot, or pass, ideally placing the user's hands in a position to generate improved power or control.

Abstract: A sporting-good implement, such as a ball bat or a lacrosse stick, includes a first handle section rotatably connected to a second handle section. The second handle section may be attached to or integral with a tapered region or barrel region of a ball bat, or with a shaft section or head of a lacrosse stick, or with another sporting-good feature. This rotatable engagement allows the relative position of the user's hands to change during the course of a swing, shot, or pass, ideally placing the user's hands in a position to generate improved power or control.

Abstract: A multi-piece shaft for a lacrosse stick includes a first section connected to a second section at a joint. The joint may be located at various shaft regions to provide a desired kick point within the shaft. In one embodiment, an outer surface of the first shaft section is separated from an inner surface of the second shaft section via an elastomeric isolator. The elastomeric isolator may be an adhesive material that bonds or secures the outer surface of the first shaft section to the inner surface of the second shaft section. Two or more of these joints optionally may be included in the lacrosse shaft.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: A ball bat includes a barrel in which one or more stiffening elements or damping elements, or both, are located. The stiffening or damping elements may be positioned at a variety of locations, and may have a variety of configurations, for selectively reducing the barrel's performance without appreciably increasing the bat's moment of inertia.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives of formula I, wherein the variables G, T, D, L, R1, R2, R3 are as described herein, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections in a patient in need thereof.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: A ball bat includes a barrel in which one or more stiffening elements or damping elements, or both, are located. The stiffening or damping elements may be positioned at a variety of locations, and may have a variety of configurations, for selectively reducing the barrel's performance without appreciably increasing the bat's moment of inertia.