Abstract: Provided herein, in certain aspects, is a binding molecule comprising an antigen binding domain and an Fc region; wherein the antigen binding domain is biparatopic or bispecific and the Fc region comprises K248E and T437R mutations (RE mutations), wherein amino acid residue numbering is according to the EU numbering system; wherein the binding molecule has increased capability of hexamerization on a cell surface, and/or increased capability of engaging C1q.

Abstract: Provided herein, in certain aspects, is a binding molecule comprising an antigen binding domain and an Fc region; wherein the antigen binding domain is monovalent and the Fc region comprises K248E and T437R mutations (RE mutations), wherein amino acid residue numbering is according to the EU numbering system; wherein the binding molecule has increased capability of hexamerization on a cell surface, and/or increased capability of engaging C1q.

Abstract: Dynamic presentation generation is disclosed, including: receiving a selection of a presentation template, wherein the presentation template references a set of assets stored at a content storage; selecting a subset of the set of assets based at least in part on a set of user inputs; and dynamically generating a presentation using at least the presentation template, the subset of the set of assets, and the set of user inputs.

Abstract: A method and test system for detecting the presence of an analyte in a sample comprising a binding region and a detecting region, where the binding region contains a plurality of magnetic beads attached to a plurality of first capture molecules that bind to an analyte of interest in the sample, and a plurality of second capture molecules having a detectable label attached thereto, where the second capture molecules bind to the analyte of interest to form a complex, where the complexes are moved through at least one liquefied aliphatic partition via a magnetic field into the detecting region that having a detection composition allows for detection and, optionally, for signal quantification.

Abstract: An RFID system comprises an array of antennas each configured to emit a plurality of beams in different directions. The beams of each pair of adjacent antennas are directed towards one another and overlap. A pair of adjacent antennas transmits simultaneously and the overlapping beams interfere to create an interference pattern. An RFID reader controls the relative phase and/or frequency of the beams to move the interference pattern to read an RFID tag within the moving pattern. As the chance of a RFID tag responding to an emitted beam generally increases with signal strength of the reader beam an area of constructive interference means that RFID tags in that region are more likely to respond to the signal. The system can cover a large proportion of the area below ceiling-mounted antennas, where cover generally means that RFID tags in that area will be successfully read.

Abstract: Provided herein are multispecific molecules comprising a first binding domain that specifically binds to polymeric immunoglobulin receptor (pIgR) and a second binding domain that specifically binds to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related methods for the treatment of patients infected with SARS-CoV-2.

Abstract: An RFID system comprises an array of antennas each configured to emit a plurality of beams in different directions. The beams of each pair of adjacent antennas are directed towards one another and overlap. A pair of adjacent antennas transmits simultaneously and the overlapping beams interfere to create an interference pattern. An RFID reader controls the relative phase and/or frequency of the beams to move the interference pattern to read an RFID tag within the moving pattern. As the chance of a RFID tag responding to an emitted beam generally increases with signal strength of the reader beam an area of constructive interference means that RFID tags in that region are more likely to respond to the signal. The system can cover a large proportion of the area below ceiling-mounted antennas, where cover generally means that RFID tags in that area will be successfully read.

Abstract: A molecule comprising a first means for engaging or activating a Natural Killer (NK) cell, and a second means for binding a tumor cell, wherein the molecule is capable of inducing NK cell dependent cytotoxicity against the tumor cell.

Abstract: An RFID system comprises an array of antennas each configured to emit a plurality of beams in different directions. The beams of each pair of adjacent antennas are directed towards one another and overlap. A pair of adjacent antennas transmits simultaneously and the overlapping beams interfere to create an interference pattern. An RFID reader controls the relative phase and/or frequency of the beams to move the interference pattern to read an RFID tag within the moving pattern. As the chance of a RFID tag responding to an emitted beam generally increases with signal strength of the reader beam an area of constructive interference means that RFID tags in that region are more likely to respond to the signal. The system can cover a large proportion of the area below ceiling-mounted antennas, where cover generally means that RFID tags in that area will be successfully read.

Abstract: A portable, personal apparatus for transporting liquid having a bottle configured to contain liquid. The bottle has a longitudinal axis. A first opening open in a direction generally parallel with the longitudinal axis in a pour position. A first cover coupled to the bottle and configured to close the first opening in a closed position. A second opening open in a direction generally orthogonal with the longitudinal axis in a fill position. A second cover coupled to the bottle and configured to close the second opening in a storage position. The second cover remaining coupled to the bottle when the second cover is in the fill position.

Abstract: Systems for, and methods of, detecting an attack on an optical communication channel are presented. The techniques can include sending, from a sender to a receiver, and over the optical communication channel, an optical signal, where the optical signal includes a classical optical signal representing first information and a quantum optical signal representing second information. The techniques can include detecting, by the receiver, third information from at least a portion of the quantum optical signal and sending, by the receiver to the sender, the third information. The techniques can include determining, by the sender, an indication of an attack on the optical communication channel based on at least a portion of the second information and the third information. The techniques can include triggering an alarm based on the determining.

Abstract: A temperature sensing device for sensing aircraft wheel brake temperature, the temperature sensing device including a surface acoustic wave, SAW, sensor element with a resonant frequency within a frequency range between 175 megahertz and 190 megahertz at a predetermined temperature. The temperature sensing system also includes a wireless relay device, a method for sensing temperature of a wheel brake of an aircraft.

Abstract: A brake disc for an aircraft wheel brake including: a temperature sensing device comprising a surface acoustic wave (SAW) sensor element and a sensor antenna, wherein the temperature sensing device is attached to the brake disc by means of a ceramic adhesive and one or more ceramic bolts. A method of attaching a temperature sensing device to a brake disc of an aircraft wheel brake.

Abstract: A cable structure to carry signals to and from a component of a temperature sensing arrangement in an aircraft wheel brake is disclosed including elongate elements including a plurality of cables and/or wires, one or more ceramic spacer layers, a ceramic cover layer and a metallic layer surrounding the one or more ceramic spacer layers and the ceramic cover layer. Also disclosed is an aircraft wheel brake comprising the cable structure and an aircraft comprising the aircraft wheel brake.

Abstract: A temperature sensing device for sensing aircraft wheel brake temperature is disclosed including a sensor antenna electrically coupled to a surface acoustic wave, SAW, sensor element, wherein: the sensor antenna comprises a conductive loop disposed on a surface of a substrate, the conductive loop surrounding an attachment region of the substrate, the attachment region having substantially no conductor material thereon. Also disclosed is a brake disc for an aircraft wheel brake comprising the temperature sensing device, and aircraft comprising the brake disc and a method of manufacturing a temperature sensing device.

Abstract: A temperature sensing device to sense aircraft wheel brake temperature is disclosed including a sensing device substrate; and one or more package layers attached to the sensing device substrate, wherein: the sensing device substrate carries one or more electronic components for sensing temperature. Also disclosed is a wireless relay device to wirelessly transmit an interrogation signal to a temperature sensing device and wirelessly receive an output signal from the temperature sensing device, the temperature sensing device to sense aircraft wheel brake temperature, the wireless relay device comprising: a relay substrate; and one or more package layers attached to the relay substrate, wherein: the relay substrate carries one or more electronic components of the wireless relay device. Also disclosed is a method of manufacturing a temperature sensing device to sense aircraft wheel brake temperature.

Abstract: A temperature sensing device for sensing aircraft wheel brake temperature, the temperature sensing device including: a surface acoustic wave (SAW) sensor element having an interdigital transducer that has electrodes disposed along the surface of a substrate forming a periodic structure. The electrodes having a thickness, in a direction perpendicular to the surface, of between 120 and 190 nanometres.

Abstract: A holder for a wireless relay device is disclosed including a rigid hollow arm member to be received in a groove in a torque tube spline of an aircraft wheel brake; and a support member to support the wireless relay device, the support member mechanically coupled to the rigid hollow arm member towards a first end of the rigid hollow arm member, wherein: the rigid hollow arm member provides a conduit for a communications cable to couple to the wireless relay device. Also disclosed is an aircraft wheel brake comprising the holder and an aircraft comprising the aircraft wheel brake.

Abstract: A portable, personal apparatus for transporting liquid having a bottle configured to contain liquid. The bottle has a longitudinal axis. A first opening open in a direction generally parallel with the longitudinal axis in a pour position. A first cover coupled to the bottle and configured to close the first opening in a closed position. A second opening open in a direction generally orthogonal with the longitudinal axis in a fill position. A second cover coupled to the bottle and configured to close the second opening in a storage position. The second cover remaining coupled to the bottle when the second cover is in the fill position.

Abstract: Methods and systems are provided for the extraction of protein rich flour and fiber rich flour from brewer's spent grains (BSG). The extraction of protein from the BSG may include preparing the BSG by controlling the temperature in a hot grain storage system and in some cases dewatering the BSG to acceptable moisture content levels. In extracting the protein rich and fiber rich flour, the BSG is conveyed to a device that dries, mills, and fractionates the BSG into separated protein and fiber extract.