Abstract: A connector for forming a fluid flow pathway by connection with a reciprocal connector. Both the connector and reciprocal connector include a fluid flow blockage part sheathed within an axially compressible sheath part. A first bearing surface receives an urging force to retract the blockage part axially along the sheath part. A terminal end of the sheath part defines a second bearing surface containing a fluid flow opening with the fluid flow blockage part retractably therein. A first chassis part includes a first catch part. A second chassis part includes a second catch part and a third bearing surface spaced from the second catch part along the second chassis part. Retraction of the blockage part forms a fluid flow pathway not sooner than immediately when the openings meet to allow fluid transfer the openings avoiding fluid leakage between connected connectors.

Abstract: An example autonomous or remotely piloted aircraft includes a virtual aperture radar system including a plurality of antennas relationally positioned on one or more surfaces of the aircraft such that individual beams from each of the plurality of antennas scan respective volumes around the aircraft and the respective volumes together substantially form an ellipsoidal field of regard around the aircraft, and a computing device having one or more processors configured to execute instructions stored in memory for performing functions of: combining the respective volumes together to form an image representative of the ellipsoidal field of regard around the aircraft, and identifying one or more objects within the image.

Abstract: A vehicle that can be modified for use in a variety of use environments and/or applications is provided. The vehicle includes a roof system includes a body and a roof system coupled to the body. The roof system includes a roof panel including a plurality of mounting points for the mounting of components and/or accessories. An interior cabin of the vehicle includes a front seating area, a rear seating area, and a cargo area. Divider panels may be secured in the vehicle to separate the front seating area, the rear seating area and the cargo area.

Abstract: A roof system for a vehicle is provided. The roof system includes a roof panel including a plurality of mounting points. A plurality of components and/or accessories may be mounted to the roof system at the plurality of mounting points. A liner panel may be coupled to the roof panel, defining an interior facing side of the roof system. The liner panel may be coupled to the roof panel by a plurality of fasteners extending through the liner panel and into the roof panel from and interior facing side of the roof system. The liner panel may include a plurality of mounting points providing for the coupling or mounting of a plurality of accessories and/or components to the interior facing side of the roof system.

Abstract: A system of divider panels for a vehicle is provided. The system includes a first divider panel that separates a front seating area from a rear seating area of the vehicle. A second divider panel separates the rear seating area from a cargo area of the vehicle. A third divider panel separates the rear seating area into two separate areas. The first, second and third dividers may be removably coupled in the interior cabin of the vehicle by mounting points defined in the roof of the vehicle, the floor of the vehicle, and seating support structure of the vehicle.

Abstract: Disclosed are small molecule inhibitors of influenza HA, and methods of using them to treat or prevent HA-mediated diseases and conditions.

Abstract: The present invention provides novel engineered HCV E2 polypeptide immunogens and related vaccine compositions that display the engineered E2 polypeptides. The invention also provides methods of using such immunogens and vaccine compositions in various therapeutic applications, e.g., for preventing or treating HCV infections.

Abstract: The present invention provides novel engineered Ebolavirus GP proteins and polypeptides, scaffolded vaccine compositions that display the engineered proteins, and polynucleotides encoding the engineered proteins and scaffolded vaccine compositions. The invention also provides methods of using such engineered Ebolavirus GP proteins and vaccine compositions in various therapeutic applications, e.g., for preventing or treating Ebolavirus infections.

Abstract: An indication of training artifacts for a machine learning model to be trained with an input data set having an access restriction is obtained. A representation of a software execution environment containing the artifacts is deployed to a computing platform within an isolated resource group which satisfies the access restriction. A trained version of the machine learning model is generated at the computing platform, and transferred outside the isolated resource group.

Abstract: A proppant container facilitates the transportation of wet sand for use in a hydraulic fracturing operation. A metering conveyor is positioned between a blender tub and a proppant motive mechanism, such as a conveyor or wash system that receives discharge direct from proppant containers of the type normally used to transport sand in support of a hydraulic fracturing operation. The metering conveyor is fitted with equipment including a knife-edge gate that may be used to facilitate flow control operations.

Abstract: A proppant container facilitates the transportation of wet sand for use in a hydraulic fracturing operation. A metering conveyor is positioned between a blender tub and a proppant motive mechanism, such as a conveyor or wash system that receives discharge direct from proppant containers of the type normally used to transport sand in support of a hydraulic fracturing operation. The metering conveyor is fitted with equipment including an intermediate surge hopper with a vibration system and a knife-edge gate that may be used to facilitate the operational movement of sand.

Abstract: The present invention relates to antibodies against influenza neuraminidase, compositions containing the antibodies and methods of using the antibodies.

Abstract: A proppant container facilitates the transportation of wet sand for use in a hydraulic fracturing operation. The proppant container is provided with a system for dislodging the wet sand for subsequent use. This may be done by use of a vibrator or an umbrella valve. In another aspect, the proppant container may be used in combination with a rack having a wash system that slurries the proppant for delivery to a blender tub without necessarily resorting to use of a conveyor belt.

Abstract: The present invention provides novel engineered Ebolavirus GP proteins and polypeptides, as well as scaffolded vaccine compositions that display the engineered proteins. The invention also provides methods of using such engineered Ebolavirus GP proteins and vaccine compositions in various therapeutic applications, e.g., for preventing or treating Ebolavirus infections.

Abstract: The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.

Abstract: A proppant container facilitates the transportation of wet sand for use in a hydraulic fracturing operation. The proppant container is provided with a system for dislodging the wet sand for subsequent use. This may be done by use of a vibrator or an umbrella valve. In another aspect, the proppant container may be used in combination with a rack having a wash system that slurries the proppant for delivery to a blender tub without necessarily resorting to use of a conveyor belt.

Abstract: The present invention provides novel engineered Ebolavirus GP proteins and polypeptides, as well as scaffolded vaccine compositions that display the engineered proteins. The invention also provides methods of using such engineered Ebolavirus GP proteins and vaccine compositions in various therapeutic applications, e.g., for preventing or treating Ebolavirus infections.

Abstract: The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to improve aircraft traffic control. An example apparatus includes a network interface to obtain air route traffic (ART) data associated with aircraft flying in airspace sectors during a first time period, a database controller to generate a first database entry by mapping extracted portions of the ART data to a first database entry field of the first database entry, and ART sector services to execute machine learning (ML) models using database entries to generate first aircraft traffic counts of the airspace sectors during the first time period, in response to selecting a first ML model of the ML models based on the first aircraft traffic counts, execute the first ML model to generate second aircraft traffic counts during a second time period, and transmit the second aircraft traffic counts to a computing device to cause an aircraft flight plan adjustment.

Abstract: The present invention provides novel engineered HCV E2 polypeptide immunogens and related vaccine compositions that display the engineered E2 polypeptides. The invention also provides methods of using such immunogens and vaccine compositions in various therapeutic applications, e.g., for preventing or treating HCV infections.