Abstract: The invention relates to a power supply unit (A) and a method for operating lighting means (6).

Abstract: The invention proposes a lighting device, in particular an emergency lighting device. The lighting device includes a first housing (2), a lighting means (12), for example an LED arranged at the first housing (2) and an electronic circuitry accommodated in the first housing (2) for operating the lighting means (12). A second housing (3) of the lighting device accommodates an energy storage means (13) such as a rechargeable battery, wherein the first housing (2) and the second housing (3) are arranged spaced apart. An interconnecting means (4) mechanically connects the first housing (2) and the second housing (3) in an elastic manner and also connects electrically the electronic circuitry and the energy storage means (13). The interconnecting means (4) of the lighting device of a preferred embodiment comprises a cable which is overmoulded to provide compressive strength in an axial direction of the cable.

Abstract: The present invention is in the field of Power over Ethernet (PoE) systems comprising a power supply module and an operation module with an emergency operation mode for operating lighting means, wherein the power supply module supplies a supply voltage via a data cable to the operation module. Especially, the present invention relates to power supply modules, preferably Power Sourcing Equipments (PSE) according to the PoE standard; operation modules with an emergency operation mode, preferably Powered devices (PD) according to the PoE standard; PoE systems, comprising such power supply modules and operation modules; and a detection method for detecting whether an operation module is arranged for operating lighting means in an emergency operation mode as well as an emergency operation mode triggering method for triggering an operation module to operate lighting means in an emergency operation mode.

Abstract: The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.

Abstract: Broadly neutralizing antibodies against HIV-1 which specifically bind to gp120 of HIV-1, a method of preparing such antibodies and the use thereof are provided.

Abstract: A method for configuring an electronic element (e.g., a ballast) in a lighting system prior to powering up the lighting system uses a wireless communication interface in the electronic element based on near field communication or radio frequency identification communication. An external configuring device, such as a programmed smartphone or tablet, is equipped with a wireless communication module and transmits configuration data to the wireless communication interface which in turn writes the data to memory in the electronic element without power being supplied to the electronic element. The control for the electronic element reads the configuration when it is powered up.

Abstract: The invention relates to a modular LED lighting unit, comprising a first module (1) to which an AC supply voltage (9) can be supplied and which comprises: a second sub-module (B), at the output of which a DC supply voltage (5) is provided which is galvanically isolated from the AC supply voltage (9), and a control unit (G), further comprising a second module (2) which comprises a further sub-module (C) supplied with the DC supply voltage (5) of the first module (1), in particular a pulsed constant current source, which is controlled by a control unit (E) of the second module (2), an LED module (F) which has at least one LED range (8) and is supplied by the further sub-module (C), inn particular a constant current source, and an emergency light operating circuit which is connected to a rechargeable energy store (ES); and takes over powering the modular LED lighting unit in the event of failure of the AC supply voltage (9).

Abstract: The invention relates to an operating device (10) for at least one light-emitting diode (9) having an input (11) for coupling to a DC bus (6) in order to receive a DC supply voltage. The operating device (10) has a configurable emergency light function. The operating device (10) is designed to produce, in the emergency light case, the LED currently for the at least one light-emitting diode (9) in dependence on how the emergency light function is configured.

Abstract: A power supply system for illuminating an LED lamp unit, having a normal mode of operation in which a mains input of a driver of the LED lamp unit is supplied by mains power, and an emergency mode of operation, in which the LED lamp unit is supplied by a charge storage device, is disclosed. The system includes an emergency mode converter operable to step-up the voltage from the charge storage device and to supply the mains driver input for illuminating the LED lamp unit.

Abstract: The present invention is in the field of Power over Ethernet (PoE) systems comprising a power supply module and an operation module with an emergency operation mode for operating lighting means, wherein the power supply module supplies a supply voltage via a data cable to the operation module. Especially, the present invention relates to power supply modules, preferably Power Sourcing Equipments (PSE) according to the PoE standard; operation modules with an emergency operation mode, preferably Powered devices (PD) according to the PoE standard; PoE systems, comprising such power supply modules and operation modules; and a detection method for detecting whether an operation module is arranged for operating lighting means in an emergency operation mode as well as an emergency operation mode triggering method for triggering an operation module to operate lighting means in an emergency operation mode.

Abstract: The invention relates to an immunogenic HIV-1 gp120 mini V3 loop, which is a truncated version of the full-length gp120 V3 loop useful for crystallization with antibodies that recognize carbohydrate moieties. The invention also relates to the structure of a broadly neutralizing antibody as a complex with a glycosylated gp120 outer domain, as determined by crystallographic techniques, and the confirmation that a glycosylated gp120 outer domain has a functional relevant conformation, as well as the determination of key residues on a glycosylated gp120 outer domain, and uses thereof and compounds and compositions therefrom. Furthermore, the invention also relates to other peptides and mimetic peptides, which bind to broadly neutralizing antibodies.

Abstract: The invention relates to a method for configuring an electronic element in a lighting system wherein the method comprises the steps of retrieving configuration information from a machine-readable medium by means of a configuring device; sending the retrieved configuration information from the configuring device to the electronic element in the lighting system; and storing the configuration information into a information storage means of the electronic element in the lighting system.

Abstract: An emergency lighting device for controlling a lighting means includes an energy store, such as a battery or an accumulator, a charging circuit for the energy store having connections for an AC voltage (alternating voltage), the charging circuit has a potential isolation element, a potentially isolated clocked converter supplied from the energy store and having a switch, preferably a flyback converter. The converter can be supplied only by the energy store, a control circuit for controlling the switch, and a supply path from the secondary side of the converter to connections for the lighting means.

Abstract: The invention relates to a power supply unit (A) and a method for operating lighting means (6).

Abstract: An emergency operating arrangement for at least one building technical device is provided, comprising a power supply unit, and an emergency supply unit, the power supply unit and the emergency supply unit being adapted to be supplied by an electrical supply and being configured to output a DC voltage, wherein the emergency supply unit is configured to detect an emergency situation and being configured to output a DC voltage higher than the DC voltage output by the power supply unit when the emergency situation is detected.

Abstract: The invention provides methods for identifying protein modulators (e.g., antibody agonists) of eukaryotic cells. The methods typically involve expressing a combinatorial agent library (e.g., via lentiviral vectors) inside a eukaryotic cell type (e.g., a mammalian cell) and then directly selecting for agents (e.g., antibodies) that are agonist of a target molecule (e.g., a signaling receptor) that modulates a phenotype of or elicits a cellular response in the cell. Some related methods involve co-culturing a cell expressing a combinatorial agent library and a second cell, and then selecting agents that modulate a phenotype of or elicit a cellular response in the second cell. Preferably, the agents are antibodies and are introduced into and expressed in the starting cells under conditions each individual cell expresses no more than 3 different members of the antibody library.

Abstract: The present invention generally relates to a support structure for Tidal Energy Converters (TECs), the support structure being for completely submerged deployment. A preferred support structure includes a single stanchion 4, extending in a first direction, and a cross arm 5, extending in a second direction perpendicular or substantially perpendicular to the first direction. The cross arm 5 is statically attached to the stanchion 4, and can support a plurality of TECs 3. A support structure also includes a support frame 7, which extends further in a third direction, perpendicular or substantially perpendicular to the first and second directions, than in the second direction. The support frame 7 is operable to anchor the support structure to a seabed.

Abstract: The invention provides methods and compositions related to adding a coating to a metal surface under low temperature conditions, such as a patina, where a binder is added to the surface, followed by a first dye, optionally the integrity of the first dye layer is disrupted to provide a mottled, cracked appearance, then a second dye layer is added, followed by a clear protective coat.

Abstract: The invention relates to a group of isolated polypeptides and derivatives that can bind genetically to immunoglobulins or antibodies. The invention also relates to industrial and other applications of these molecules, e.g., antibody purifications.