Patents by Inventor Ilya Fine

Ilya Fine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11134901
    Abstract: Methods and systems of optically measuring systolic and/or diastolic blood pressure of a mammal having biological tissue are disclosed herein. In some embodiments, the system comprises an optical blood motion sensor, a gas-sealable inflatable cushion having a flexible and transparent (FOT) barrier section, and an optical blood motion sensor comprising a laser. When pressure (e.g. at least systolic pressure) illuminates the tissue, laser light may pass en route to the tissue through the FOT sealing barrier section of the gas-sealable inflatable cushion as well as cushion interior. In some embodiments, a rigid restrictor comprising an optically transparent section is provided, and laser light also passes through the optically transparent section of the rigid restrictor en route to the biological tissue.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: October 5, 2021
    Assignee: ELFI-TECH LTD.
    Inventors: Ilya Fine, Alexander Kaminsky
  • Publication number: 20210235994
    Abstract: Methods and apparatus for optically detecting biologically-sourced acoustic signal(s) are disclosed herein. In some embodiments, K-sounds are detected and/or blood pressure is measured. Alternatively or additionally, an optical stethoscope (e.g. diffused-light interferometer optical stethoscope) is employed.
    Type: Application
    Filed: February 11, 2021
    Publication date: August 5, 2021
    Inventors: Evgeny Seider, Yossi Kleinman, Naum Chernoguz, Alexander Finarov, Ilya FINE
  • Publication number: 20210093204
    Abstract: A method and apparatus for hemodynamically characterizing a neurological or fitness state by dynamic scattering light (DLS) is disclosed herein. In particular, a non-pulsatile blood-shear-rate-descriptive (BSRD) signal(s) is optically generated and analyzed. In some embodiments, the BSRD signal is generated dynamically so as to adaptively maximize (i.e. according to a bandpass or frequency-selection profile) a prominence of a predetermined non-pulsatile physiological signal within the BSRD. In some embodiments, the BSRD is subjected to a stochastic or stationary-status analysis. Alternatively or additionally, the neurological or fitness state may be computed from multiple BSRDs, including two or more of: (i) a [sub-200 Hz, ˜300 Hz] BSRD signal; (ii) a [˜300 Hz, ˜1000 Hz] signal; (iii) a [˜1000 Hz, ˜4000 Hz] signal and (iv) a [4000 Hz, z Hz] (z>=7,000) signal.
    Type: Application
    Filed: August 13, 2020
    Publication date: April 1, 2021
    Inventors: Ilya FINE, Alexander Kaminsky
  • Patent number: 10952622
    Abstract: A method and apparatus for hemodynamically characterizing a neurological or fitness state by dynamic scattering light (DLS) is disclosed herein. In particular, a non-pulsatile blood-shear-rate-descriptive (BSRD) signal(s) is optically generated and analyzed. In some embodiments, the BSRD signal is generated dynamically so as to adaptively maximize (i.e. according to a bandpass or frequency-selection profile) a prominence of a predetermined non-pulsatile physiological signal within the BSRD. In some embodiments, the BSRD is subjected to a stochastic or stationary-status analysis. Alternatively or additionally, the neurological or fitness state may be computed from multiple BSRDs, including two or more of: (i) a [sub-200 Hz, ˜300 Hz] BSRD signal; (ii) a [˜300 Hz, ˜1000 Hz] signal; (iii) a [˜1000 Hz, ˜4000 Hz] signal and (iv) a [˜4000 Hz, z Hz] (z>=7,000) signal.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: March 23, 2021
    Assignee: ELFI-TECH LTD.
    Inventors: Ilya Fine, Alexander Kaminsky
  • Patent number: 10720755
    Abstract: Embodiments of the invention relate to a method and apparatus for measuring at least one parameter that is (i) descriptive of stochastic motion of suspended particles within a fluid; and/or (ii) is a rheological property of the fluid or of the suspension; (iii) describes a concentration of suspended particles within the fluid; and/or (iv) is a diffusion coefficient of the suspended particles and/or (iv) is a viscosity of the fluid or of the suspension; and/or (v) is a food aging or spoilage parameter and/or (vii) is an in-vivo or in-vitro blood coagulation parameter.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: July 21, 2020
    Assignee: ELFI-TECH LTD.
    Inventors: Ilya Fine, Alexander Kaminsky
  • Publication number: 20190312411
    Abstract: Embodiments of the invention relate to a method and apparatus for measuring at least one parameter that is (i) descriptive of stochastic motion of suspended particles within a fluid; and/or (ii) is a rheological property of the fluid or of the suspension; (iii) describes a concentration of suspended particles within the fluid; and/or (iv) is a diffusion coefficient of the suspended particles and/or (iv) is a viscosity of the fluid or of the suspension; and/or (v) is a food aging or spoilage parameter and/or (vii) is an in-vivo or in-vitro blood coagulation parameter.
    Type: Application
    Filed: February 7, 2018
    Publication date: October 10, 2019
    Inventor: Ilya FINE
  • Publication number: 20190298186
    Abstract: Methods and systems of optically measuring systolic and/or diastolic blood pressure of a mammal having biological tissue are disclosed herein. In some embodiments, the system comprises an optical blood motion sensor, a gas-sealable inflatable cushion having a flexible and transparent (FOT) barrier section, and an optical blood motion sensor comprising a laser. When pressure (e.g. at least systolic pressure) illuminates the tissue, laser light may pass en route to the tissue through the FOT sealing barrier section of the gas-sealable inflatable cushion as well as cushion interior. In some embodiments, a rigid restrictor comprising an optically transparent section is provided, and laser light also passes through the optically transparent section of the rigid restrictor en route to the biological tissue.
    Type: Application
    Filed: April 12, 2019
    Publication date: October 3, 2019
    Inventors: Ilya Fine, Alexander Kaminsky
  • Publication number: 20190008397
    Abstract: A method and apparatus for hemodynamically characterizing a neurological or fitness state by dynamic scattering light (DLS) is disclosed herein. In particular, a non-pulsatile blood-shear-rate-descriptive (BSRD) signal(s) is optically generated and analyzed. In some embodiments, the BSRD signal is generated dynamically so as to adaptively maximize (i.e. according to a bandpass or frequency-selection profile) a prominence of a predetermined non-pulsatile physiological signal within the BSRD. In some embodiments, the BSRD is subjected to a stochastic or stationary-status analysis. Alternatively or additionally, the neurological or fitness state may be computed from multiple BSRDs, including two or more of: (i) a [sub-200 Hz, ˜300 Hz] BSRD signal; (ii) a [˜300 Hz, ˜1000 Hz] signal; (iii) a [˜1000 Hz, ˜4000 Hz] signal and (iv) a [˜4000 Hz, z Hz] (z>=7,000) signal.
    Type: Application
    Filed: August 15, 2016
    Publication date: January 10, 2019
    Inventors: Ilya FINE, Alexander KAMINSKY
  • Publication number: 20180310891
    Abstract: Methods and systems of optically measuring systolic and/or diastolic blood pressure of a mammal having biological tissue are disclosed herein. In some embodiments, the system comprises an optical blood motion sensor, a gas-sealable inflatable cushion having a flexible and transparent (FOT) barrier section, and an optical blood motion sensor comprising a laser. When pressure (e.g. at least systolic pressure) illuminates the tissue, laser light may pass en route to the tissue through the FOT sealing barrier section of the gas-sealable inflatable cushion as well as cushion interior. In some embodiments, a rigid restrictor comprising an optically transparent section is provided, and laser light also passes through the optically transparent section of the rigid restrictor en route to the biological tissue.
    Type: Application
    Filed: March 28, 2018
    Publication date: November 1, 2018
    Inventors: Ilya FINE, Alexander Kaminsky
  • Publication number: 20180160913
    Abstract: A system, method and medical tool are presented for use in non-invasive in vivo determination of at least one desired parameter or condition of a subject having a scattering medium in a target region. The measurement system comprises an illuminating system, a detection system, and a control system. The illumination system comprises at least one light source configured for generating partially or entirely coherent light to be applied to the target region to cause a light response signal from the illuminated region. The detection system comprises at least one light detection unit configured for detecting time-dependent fluctuations of the intensity of the light response and generating data indicative of a dynamic light scattering (DLS) measurement. The control system is configured and operable to receive and analyze the data indicative of the DLS measurement to determine the at least one desired parameter or condition, and generate output data indicative thereof.
    Type: Application
    Filed: September 12, 2017
    Publication date: June 14, 2018
    Inventor: Ilya FINE
  • Publication number: 20180153420
    Abstract: Apparatus and methods for optical and non-invasive measurement of cardiovascular fitness and/or stress and/or physiological parameters are disclosed herein.
    Type: Application
    Filed: November 14, 2017
    Publication date: June 7, 2018
    Inventors: Ilya FINE, Alexander Kaminsky
  • Patent number: 9730622
    Abstract: A wearable pulse oximetry device and associated methods are provided. In some embodiments, the device includes at least two light sources having different wavelengths and at least one detector responsive to the different wavelengths. The device also includes a structure adapted to fixate at a distal end of the wearer's ulna bone at a fixated area. The light sources having different wavelengths and the at least one detector are fixed within, or adjacent to, the structure such that when the structure fixates at the fixated area the light sources and the at least one detector are positioned adjacent to the distal end of the ulna, and the at least one detector is positioned to detect light emitted from the at least two light sources.
    Type: Grant
    Filed: April 12, 2016
    Date of Patent: August 15, 2017
    Assignee: Oxitone Medical Ltd.
    Inventors: Leon Eisen, Ilya Fine, Leonid Goldinov
  • Publication number: 20160278676
    Abstract: A wearable pulse oximetry device and associated methods are provided. In some embodiments, the device includes at least two light sources having different wavelengths and at least one detector responsive to the different wavelengths. The device also includes a structure adapted to fixate at a distal end of the wearer's ulna bone at a fixated area. The light sources having different wavelengths and the at least one detector are fixed within, or adjacent to, the structure such that when the structure fixates at the fixated area the light sources and the at least one detector are positioned adjacent to the distal end of the ulna, and the at least one detector is positioned to detect light emitted from the at least two light sources.
    Type: Application
    Filed: April 12, 2016
    Publication date: September 29, 2016
    Applicant: Oxitone Medical Ltd.
    Inventors: Leon Eisen, Ilya Fine, Leonid Goldinov
  • Patent number: 9314197
    Abstract: A pulse oximetry device that is mounted on a wrist strap and fixates an area above a distal end of the ulna with a dome shaped structure. This area is used as measuring area. The measurement is carried out by a detector positioned above the fixated area, that detects light emitted by light sources having different wave lengths that are located at a periphery of the fixated area. Hence, the reflections are measured at neither a reflection mode nor a transmission mode, but are at an angle between 20° and 160° from the emitted light. This mode, termed trans-illumination, allows achieving an excellent signal to noise ratio that for the first time enables continuous and reliable measurement of oximetry data on the wrist.
    Type: Grant
    Filed: August 26, 2012
    Date of Patent: April 19, 2016
    Assignee: OXITONE MEDICAL LTD.
    Inventors: Leon Eisen, Ilya Fine, Leonid Goldinov
  • Patent number: 9149216
    Abstract: A system and method for measuring one or more light-absorption related blood analyte concentration parameters of a mammalian subject, is disclosed. In some embodiments, the system comprises: a) a photoplethysmography (PPG) device configured to effect a PPG measurement by illuminating skin of the subject with at least two distinct wavelengths of light and determining relative absorbance at each of the wavelengths; b) a dynamic light scattering measurement (DLS) device configured to effect a DLS measurement of the subject to rheologically measure a pulse parameter of the subject; and c) electronic circuitry configured to: i) temporally correlating the results of the PPG and DLS measurements; and ii) accordance with the temporal correlation between the PPG and DLS measurements, assessing value(s) of the one or more light-absorption related blood analyte concentration parameter(s).
    Type: Grant
    Filed: October 1, 2014
    Date of Patent: October 6, 2015
    Assignee: Oxitone Medical Ltd.
    Inventors: Leon Eisen, Alexander Kaminsky, Ilya Fine
  • Publication number: 20150141766
    Abstract: The present disclosure relates to apparatus and method for optical measurement of cardiovascular recovery and/or a respiration rate. In some embodiments, an apnea detector generates an alert signal if the computed respiration rate drops below a threshold.
    Type: Application
    Filed: September 30, 2014
    Publication date: May 21, 2015
    Inventor: Ilya Fine
  • Patent number: 8868149
    Abstract: A system and method for measuring one or more light-absorption related blood analyte concentration parameters of a mammalian subject, is disclosed. In some embodiments, the system comprises: a) a photoplethysmography (PPG) device configured to effect a PPG measurement by illuminating skin of the subject with at least two distinct wavelengths of light and determining relative absorbance at each of the wavelengths; b) a dynamic light scattering measurement (DLS) device configured to effect a DLS measurement of the subject to rheologically measure a pulse parameter of the subject; and c) electronic circuitry configured to: i) temporally correlating the results of the PPG and DLS measurements; and ii) accordance with the temporal correlation between the PPG and DLS measurements, assessing value(s) of the one or more light-absorption related blood analyte concentration parameter(s).
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: October 21, 2014
    Assignee: Oxitone Medical Ltd.
    Inventors: Leon Eisen, Alexander Kamisnky, Ilya Fine
  • Publication number: 20140200423
    Abstract: A pulse oximetry device that is mounted on a wrist strap and fixates an area above a distal end of the ulna with a dome shaped structure. This area is used as measuring area. The measurement is carried out by a detector positioned above the fixated area, that detects light emitted by light sources having different wave lengths that are located at a periphery of the fixated area. Hence, the reflections are measured at neither a reflection mode nor a transmission mode, but are at an angle between 20° and 160° from the emitted light. This mode, termed trans-illumination, allows achieving an excellent signal to noise ratio that for the first time enables continuous and reliable measurement of oximetry data on the wrist.
    Type: Application
    Filed: August 26, 2012
    Publication date: July 17, 2014
    Applicant: Oxitone Medical Ltd.
    Inventors: Leon Eisen, Ilya Fine, Leonid Goldinov
  • Patent number: 8708907
    Abstract: Embodiments of the present invention relate to a system and method for in vivo measurement of blood parameters by processing analog electrical signals from a plurality of photodetectors. In some embodiments, it is possible to determine one or more blood parameters according to (i) a first electrical signal from a first detector and (ii) a second electrical signal from a second photodetector. A difference analog electrical signal is generated, indicative of a difference between the light response signal at the first location and light response signal at the second location, is generated. One or more blood parameters may be detected according to the difference analog electrical signal.
    Type: Grant
    Filed: May 5, 2010
    Date of Patent: April 29, 2014
    Assignee: Elfi-Tech
    Inventors: Ilya Fine, Alexander Kaminsky
  • Publication number: 20140094666
    Abstract: A system, method and medical tool are presented for use in non-invasive in vivo determination of at least one desired parameter or condition of a subject having a scattering medium in a target region. The measurement system comprises an illuminating system, a detection system, and a control system. The illumination system comprises at least one light source configured for generating partially or entirely coherent light to be applied to the target region to cause a light response signal from the illuminated region. The detection system comprises at least one light detection unit configured for detecting time-dependent fluctuations of the intensity of the light response and generating data indicative of a dynamic light scattering (DLS) measurement. The control system is configured and operable to receive and analyze the data indicative of the DLS measurement to determine the at least one desired parameter or condition, and generate output data indicative thereof.
    Type: Application
    Filed: September 28, 2012
    Publication date: April 3, 2014
    Applicant: ELFI-TECH LTD.
    Inventor: Ilya FINE