Abstract: The present invention relates to a medium composition for enhancing the self-renewal ability of stem cells, which contains apelin, and a method of culturing stem cells using the medium composition. According to the present invention, stem cells can be effectively cultured to proliferate without changing the characteristics of the cells, and the telomerase activity of stem cells can be increased. Thus, the efficacy of cell therapy based on stem cells can be significantly improved.

Abstract: A semiconductor system includes a semiconductor device suitable for not performing an internal refresh operation when entering a self-refresh mode in response to a self-refresh command, and cutting off input of an auto-refresh command when exiting the self-refresh mode.

Abstract: The present disclosure relates to a medium composition for culturing stem cells, and more specifically, to a medium composition for culturing mesenchymal stem cells, in which the medium composition includes a basic medium in which various quasi-completed mediums (DMEM, ?-MEM, IMDM, F12, and DMEM/F12) are mixed, L-ascorbic acid 2-phosphate, fetal bovine serum, basic fibroblast growth factors (b-FGF), insulin, N-acetyl-L-cysteine, calcium chloride, and hydrocortisone. According to the present disclosure, it is capable of improving proliferation ability and differentiation ability of the mesenchymal stem cells, and is capable of producing cell therapy products more economically using the mesenchymal stem cells by enabling the mesenchymal stem cells to be cultured at a low price compared to the existing culturing methods.

Abstract: A semiconductor system includes a semiconductor device suitable for not performing an internal refresh operation when entering a self-refresh mode in response to a self-refresh command, and cutting off input of an auto-refresh command when exiting the self-refresh mode.

Abstract: Provided is a method for making an herbal soap for alleviating atopic skin disease, the method comprising combining five main medicinal herbs consisting of Kalopanacis cortex, Amaranthus mangostanus, Gardenia jasminoides, Lonicerae flos and Rumex japonicus Houtt with four supplementary medicinal herbs consisting of Glycyrrhiza uralensis Fischer, Mori cortex, Phaseoli radiati semen and red ginseng, which serve to increase the efficacies of the five main medicinal herbs, and refined horse fat containing unsaturated fatty acids and vitamin E, according to an herb combination method that is used in Chinese medicine. According to the method, active ingredients effective for atopic dermatitis patients can be extracted from the medicinal herbs. The herbal extract obtained according to the method exhibits excellent effects on the fundamental treatment of diseases having a high correlation with atopic dermatitis patients and on the alleviation of atopic dermatitis.

Abstract: A driving signal control circuit includes a discharge circuit, a counter circuit, and a control circuit. The discharge circuit is configured to compare a monitored voltage and a reference voltage, and generate a discharge signal. The monitored voltage is proportional to a core voltage. The counter circuit is configured to perform an up/down count operation according to the discharge signal, and generate a count signal. The control circuit is configured to generate a driving signal which has an enable period proportional to the count signal.

Abstract: The present invention relates to a medium composition for transforming stem cells from an aged person into young stem cells, and more particularly to a medium composition for culturing stem cells, which is used to rejuvenate stem cells from an aged person so as to have characteristics similar to those of the stem cells of young people, and to a method for rejuvenating stem cells, which comprises culturing stem cells from an aged person in the medium composition. According to the present invention, even mesenchymal stem cells collected from over 60 years old patients can be transformed into young mesenchymal stem cells having high differentiation ability, high telomerase activity, and high ability to express stem cell markers. Thus, the present invention can significantly increase the efficacy of cell therapy employing mesenchymal stem cells.

Abstract: A semiconductor device includes a decoded signal generation circuit suitable for executing a counting operation to generate a decoded signal in response to an oscillation signal during a refresh section, a refresh pulse generation circuit suitable for generating a refresh pulse for executing a refresh operation in response to the decoded signal and a temperature code, and a reset pulse generation circuit suitable for generating a reset pulse initializing the decoded signal in response to the refresh pulse.

Abstract: A semiconductor device includes a decoded signal generation circuit suitable for executing a counting operation to generate a decoded signal in response to an oscillation signal during a refresh section, a refresh pulse generation circuit suitable for generating a refresh pulse for executing a refresh operation in response to the decoded signal and a temperature code, and a reset pulse generation circuit suitable for generating a reset pulse initializing the decoded signal in response to the refresh pulse.

Abstract: A driving signal control circuit includes a discharge circuit, a counter circuit, and a control circuit. The discharge circuit is configured to compare a monitored voltage and a reference voltage, and generate a discharge signal. The monitored voltage is proportional to a core voltage. The counter circuit is configured to perform an up/down count operation according to the discharge signal, and generate a count signal. The control circuit is configured to generate a driving signal which has an enable period proportional to the count signal.

Abstract: An embryonic stem cell line derived from a nucleus-transferred oocyte prepared by transferring a nucleus of a human somatic cell into an enucleated human oocyte may differentiate into various desired cell types.

Abstract: There is provided a method for preventing disruption and aggregation of stem cells. In addition, there is provided a stem cell composition for intravascular administration, in which stem cells are suspended in a solution containing aspirin. Further, there is provided a composition for preventing disruption or aggregation of stem cells, in which stem cells are suspended in a solution containing aspirin. According to the present invention, disruption and aggregation of cells may be prevented during transport or storage, such that the administered stem cells may stably reach the target tissue and exhibit the activity thereof in a more efficient manner, thereby remarkably increasing the effect of cell therapy using stem cells.

Abstract: A semiconductor device may include a refresh controller and a bank active signal generator. The refresh controller may be suitable for generating a level signal, setting a level of the level signal in response to a refresh pulse signal while operating in a test mode, and suitable for receiving a refresh flag signal and generating a first period signal and a second period signal in response to the level signal. The bank active signal generator may be suitable for generating bank active signals for a first bank group in response to the first period signal, and generating bank active signals for a second bank group in response to the second period signal.

Abstract: Disclosed therein is an air conditioner for a vehicle. The air conditioner includes console air volume distribution means formed on a mode cam to control the degree of opening of a console door in order to vary distribution of air volume of a console vent by air discharge modes, thereby preventing an excessive discharge of air to a console vent (rear seat) by regulating the console vent to be opened less in a floor mode and a mixing mode, which are air discharge modes of a heating mode, than when the console vent is opened the greatest, preventing displeasure of a passenger who is seating on a rear seat, enhancing heating performance, and preventing the lack of air volume in a front seat.

Abstract: The present invention relates to a medium composition for enhancing the self-renewal ability of stem cells, which contains apelin, and a method of culturing stem cells using the medium composition. According to the present invention, stem cells can be effectively cultured to proliferate without changing the characteristics of the cells, and the telomerase activity of stem cells can be increased. Thus, the efficacy of cell therapy based on stem cells can be significantly improved.

Abstract: The present invention relates to a stem cell composition for intravenous administration, which contains stem cells at a concentration of 1×107 to 5×108 cells/ml, in which the stem cells have a diameter of 10-20 ?m and are present as single cells. The stem cell composition according to the present invention is suitable for intravenous administration, and enables the stem cells to securely reach a target tissue after intravascular administration so as to exhibit their activity in the target tissue. Thus, it can significantly increase the therapeutic effects of the stem cells.

Abstract: A heating system for a hybrid vehicle may include a first heating line connecting an engine, having a temperature which is controlled through water-cooling, to a heater core that is heated using a heat generated from the engine, a second heating line allowing for heat exchange between various electronic devices and an auxiliary radiator controlling the temperatures of the various electronic devices, a branch line connected to the first heating line and the second heating line and exchanging heat therebetween, a plurality of valves provided on each of the first heating line, the second heating line, and the branch line, and a controller controlling each valve.

Abstract: The present invention relates to a method for preparing stem cells in high concentration. The present invention makes it possible to grow stem cells in an amount sufficient to be clinically usable in a short time, and makes it possible to relatively efficiently enhance the ability of administered stem cells to efficaciously reach target tissue and exhibit an action in a stable fashion and can therefore dramatically increase the efficacy of cell therapy using stem cells.

Abstract: There is provided a method for preventing disruption and aggregation of stem cells. In addition, there is provided a stem cell composition for intravascular administration, in which stem cells are suspended in a solution containing aspirin. Further, there is provided a composition for preventing disruption or aggregation of stem cells, in which stem cells are suspended in a solution containing aspirin. According to the present invention, disruption and aggregation of cells may be prevented during transport or storage, such that the administered stem cells may stably reach the target tissue and exhibit the activity thereof in a more efficient manner, thereby remarkably increasing the effect of cell therapy using stem cells.

Abstract: The present invention relates to a method for preparing stem cells having a size suitable for intravascular administration, and preferably to a method for preparing stem cells with a diameter ranging from 11-16 ?m. Additionally, the present invention relates to media composition for preparing stem cells having a size suitable for intravascular administration. According to the present invention, stem cells having a size suitable for intravascular administration can be prepared such that stem cells administered into a vein can stably reach a target tissue, and thus can more efficiently increase efficacy displaying activity, thereby innovatively enhancing the efficacy of cell therapy using stem cells.