Abstract: The present disclosure is the first to identify a host cell protein and its function with which MPT63 and MPT64, secreted antigens of Mycobacterium tuberculosis, interact, and to construct a recombinant MPT protein including each domain of MPT63 and MPT64 interacting with the host cell protein, and the recombinant MPT protein may be applied to a use for the prevention and treatment of tuberculosis by confirming that the recombinant MPT protein targets the Mycobacterium tuberculosis-infected macrophages and increases the ROS level and inflammatory cytokine expression in macrophages, thereby inducing the death of Mycobacterium tuberculosis. And MPT protein of the present disclosure can improve the vaccine effect by the BCG vaccine so that it can be used as a tuberculosis vaccine and/or vaccine adjuvant either alone or together with known tuberculosis vaccines.

Abstract: The present invention relates to a novel Toxoplasma gondii GRA8-derived recombinant peptide, and a pharmaceutical composition and functional food for preventing or treating cancer, which includes the same as an active ingredient. The Toxoplasma gondii GRA8-derived recombinant peptide according to the present invention is a novel recombinant peptide in which a specific mitochondrial targeting sequence and an ATP5A1/SIRT3 sequence of GRA8 are conjugated to an acidity-triggered rational membrane (ATRAM), and has considerably improved efficacy in which an inhibitory concentration 50 (IC50) is improved up to 200-fold (in vitro) or 500-fold (in vivo), compared with a conventional GRA8-derived peptide (rGRA8). In addition, since the peptide treatment shows a notably distinct therapeutic effect in mouse models with cancer, the peptide may be effectively used in a pharmaceutical composition or functional food for preventing or treating cancer.

Abstract: The application relates to the technical field of semiconductor manufacturing, and in particular relates to a front opening unified pod, a wafer transfer system and a wafer transfer method. The front opening unified pod includes a body, a wafer scanning device and a cover. The body is provided with an opening communicating with an interior of the body. The wafer scanning device includes a first wafer scanning device, is arranged on an inner wall of the body, and is configured to scan a storage condition of wafers in the body. The cover is fastened at the opening. The wafer scanning device is arranged on the inner wall of the body of the front opening unified pod, and the wafer scanning device scans and confirms the storage condition of the wafers in the front opening unified pod in real time.

Abstract: The knee joint prosthesis includes a tibial component and a femoral component. The tibial component has a top surface, a bottom surface opposite to the top surface and a first slot passing through the top surface and the bottom surface for accommodating a cruciate ligament. The tibial component has at least one first protrusion disposed on the bottom surface. The femoral component is carried by the tibial component and has a second slot for accommodating the cruciate ligament. The femoral component has at least one second protrusion disposed on a surface thereof opposite to the tibial component. The at least one first protrusion includes a receded incision positioned on a rear edge of the at least one first protrusion and the receded incision is receded in a direction from posterior to anterior.

Abstract: Provided is a financial service providing method of an electronic apparatus comprising checking whether a financial service is available for a user based on the user's first sales information, checking a condition of use of the financial service for the user based on the user's second sales information, providing information on whether the financial service is available and the condition of use to an external apparatus, providing unsettled sales information of the user based on an information request from the external apparatus, and changing payment account information of a sales price to be paid to the user based on receiving information related to approval of providing the financial service from the external apparatus. Other example embodiments are also possible.

Abstract: A method for preparing a SiC ingot includes: disposing a raw material and a SiC seed crystal facing each other in a reactor having an internal space; subliming the raw material by controlling a temperature, a pressure, and an atmosphere of the internal space; growing the SiC ingot on the seed crystal; and collecting the SiC ingot after cooling the reactor. The wafer prepared from the ingot, which is prepared from the method, generates cracks when an impact is applied to a surface of the wafer, the impact is applied by an external impact source having mechanical energy, and a minimum value of the mechanical energy is 0.194 J to 0.475 J per unit area (cm2).

Abstract: The present invention relates to a pharmaceutical composition and a health functional food composition for preventing, alleviating or treating inflammatory diseases, including Toxoplasma gondii GRA9 protein or a gene encoding the protein as an active ingredient. The present inventors have identified the C-terminal region essential for the NLRP3-mediated mechanism of action and function of Toxoplasma gondii GRA9 in macrophages, which are host immune cells and confirmed the substantial anti-inflammatory and antibacterial effects and the antiseptic effect in vivo. Accordingly, Toxoplasma gondii GRA9 protein or a gene encoding the protein is expected to be usefully utilized in the field of prevention or treatment of inflammatory diseases caused by an abnormal NLRP3-mediated inflammatory response, including sepsis.

Abstract: An adhesive layer of seed crystal includes a graphitized adhesive layer, wherein the graphitized adhesive layer is prepared by heat-treating a pre-carbonized adhesive layer, and wherein the adhesive layer has Vr value of 28%/mm3 or more, and the Vr value is represented by Equation 1 below: Vr ? = { Sq ( V ? 1 - V ? 2 ) } × 1 ? 0 3 [ Equation ? ? 1 ] where Sg (%) is represented by Equation 2 below, V1 is a volume (mm3) of the pre-carbonized adhesive layer, and V2 is a volume (mm3) of the graphitized adhesive layer, Sg ? = { 1 - ( A ? 2 A ? 1 ) } × 1 ? 0 ? 0 ? % [ Equation ? ? 2 ] where A1 is an area (mm2) of the pre-carbonized adhesive layer, and A2 is an area (mm2) of the graphitized adhesive layer.

Abstract: The knee joint prosthesis includes a tibial component and a femoral component. The tibial component has a top surface, a bottom surface opposite to the top surface and a first slot passing through the top surface and the bottom surface for accommodating a cruciate ligament. The tibial component has at least one first protrusion disposed on the bottom surface, and the first protrusion has a plurality of first through holes. The femoral component is carried by the tibial component and has a second slot for accommodating the cruciate ligament. The femoral component has at least one second protrusion disposed on a surface thereof opposite to the tibial component, and the second protrusion has a plurality of second through holes. The first protrusion has a first rear and front portions, and a width of the first protrusion gradually becomes thicker from the first rear portion toward the first front portion.

Abstract: The present invention relates to a use of a peptide containing an amino acid sequence represented by SEQ ID NO: 1 derived from the Rv2626c protein of Mycobacterium tuberculosis for treating sepsis. The peptide is excellent in inhibiting the inflammatory response induced by macrophages and is excellent in inhibiting the increase in the number of bacterial colonies, and thus can be usefully used for the treatment of sepsis.

Abstract: The invention provides a method of cleaning a vehicle comprising: providing a powder composition; providing water; mixing the powder composition and the water to form a liquid cleaning formulation; and applying the liquid cleaning formulation to a surface of a vehicle, wherein the powder composition comprising: surfactant; silicate selected from magnesium lithium silicates and mixtures thereof; hygroscopic agent; at least 20 wt % carbonate salt; and at least 20 wt % acid.

Abstract: A method for preparing a SiC ingot includes preparing a crucible assembly comprising a crucible body having an internal space, loading a raw material into the internal space of the crucible body and placing a plurality of SiC seed in the internal space of the crucible body at regular intervals spaced apart from the raw material, and growing the SiC ingot from the plurality of SiC seed by adjusting the internal space of the crucible body to a crystal growth atmosphere such that the raw material is vapor-transported and deposited to the plurality of SiC seed. A density of the crucible body may be 1.70 to 1.92 g/cm3.

Abstract: A silicon carbide ingot manufacturing method and a silicon carbide ingot manufacturing system are provided. The silicon carbide ingot manufacturing method and the silicon carbide ingot manufacturing system may change a temperature gradient depending on the growth of an ingot by implementing a guide which has a tilted angle to an external direction from the interior of a reactor, in an operation to grow an ingot during a silicon carbide ingot manufacturing process.

Abstract: The present invention relates to a composition for use in preventing, alleviating, or treating inflammatory disease, or an anti-inflammatory composition, which comprises: ?-1,3-glucan; and the peptide composed of the amino acid sequence of SEQ ID NO: 4. The present invention also relates to an antibacterial composition against bacteria causative of sepsis, which comprises: ?-1,3-glucan; the peptide composed of the amino acid sequence of SEQ ID NO: 4; and an antibiotic. The present invention also relates to a method for preventing or treating an inflammatory disease, the method comprising a step of administering ?-1,3-glucan; and the peptide composed of the amino acid sequence of SEQ ID NO: 4 to a patient.

Abstract: A method of cleaning a wafer comprises: a scrubbing operation comprising treating a target wafer to be cleaned with a brush at a rotation rate of 200 rpm or less to prepare a brush cleaned wafer; and a cleaning operation comprising cleaning the brush cleaned wafer with a cleaning solution to prepare a cleaned bare wafer, wherein the cleaning operation comprises a first cleaning operation and a second cleaning operation sequentially.

Abstract: A stereotactic device for primate brains indicates a brain coordinate reference point of a primate using a simulator for indicating a brain coordinate reference point, thereby providing an initial setting to a zero point corresponding to the brain coordinate reference point. The brain coordinate reference point is conveniently and accurately indicated without relatively expensive equipment, such as a magnetic resonance imaging (MRI) scanner, to determine brain coordinates of the primate, so that a targeting procedure can be conducted on the brain.

Abstract: A silicon carbide ingot manufacturing method and a silicon carbide ingot manufacturing system are provided. The silicon carbide ingot manufacturing method and the silicon carbide ingot manufacturing system may change a temperature gradient depending on the growth of an ingot by implementing a guide which has a tilted angle to an external direction from the interior of a reactor, in an operation to grow an ingot during a silicon carbide ingot manufacturing process.

Abstract: A high voltage battery unit for a vehicle and an underbody of the vehicle are provided. The high voltage battery unit mounted to the vehicle is installed under a center floor of the vehicle at the outdoor side. A drive shaft forming a drive device of the vehicle is installed to penetrate between battery built-in parts positioned at both sides with respect to a center tunnel to deliver the power of a powertrain mounted at the front of the vehicle to a rear wheel through the drive shaft.

Abstract: A body of a vehicle equipped with a high-voltage battery is disclosed. The vehicle body includes a rear cross member mounted below the rear side of the front seat so as to be oriented in the lateral direction of the vehicle body, a front cross member mounted in front of the rear cross member so as to be oriented in the lateral direction of the vehicle body, a high-voltage battery mounted between the front cross member and the rear cross member, and a plurality of longitudinal support members mounted to support the bottom of the high-voltage battery and to connect the front cross member and the rear cross member to each other in the longitudinal direction of the vehicle body.

Abstract: A wafer having relaxation moduli different by 450 GPa or less, as determined by dynamic mechanical analysis, when loaded to 1 N and 18 N with a loading rate of 0.1 N/min at a temperature of 25° C.