Patents by Inventor Ingemar Starke

Ingemar Starke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IBAT inhibitors for the treatment of liver diseases
    Patent number: 10000528
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: June 19, 2018
    Assignee: Albireo AB
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT INHIBITORS FOR THE TREATMENT OF LIVER DISEASES
    Publication number: 20180162904
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Application
    Filed: February 12, 2018
    Publication date: June 14, 2018
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT INHIBITORS FOR THE TREATMENT OF LIVER DISEASES
    Publication number: 20180030089
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Application
    Filed: October 5, 2017
    Publication date: February 1, 2018
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT INHIBITORS FOR THE TREATMENT OF LIVER DISEASES
    Publication number: 20180030088
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Application
    Filed: October 5, 2017
    Publication date: February 1, 2018
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT INHIBITORS FOR THE TREATMENT OF LIVER DISEASES
    Publication number: 20180022776
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Application
    Filed: October 2, 2017
    Publication date: January 25, 2018
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT inhibitors for the treatment of liver disease
    Patent number: 9694018
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: July 4, 2017
    Assignee: Albireo AB
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT Inhibitors for the Treatment of Liver Disease
    Publication number: 20170182059
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Application
    Filed: September 26, 2016
    Publication date: June 29, 2017
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • PHARMACEUTICAL COMBINATION COMPRISING AN IBAT INHIBITOR AND A BILE ACID BINDER
    Publication number: 20170182115
    Abstract: The present invention relates to a combination comprising a substance with inhibiting effect on the ileal bile acid transport system (I BAT) and at least one other active substance selected from an IBAT inhibitor; an enteroendocrine peptide or enhancer thereof; a dipeptidyl peptidase-IV inhibitor; a biguanidine; an incretin mimetic; a thiazolidinone; a PPAR agonist; a HMG Co-A reductase inhibitor; a bile acid binder; and a TGR5 receptor modulator; wherein the IBAT inhibitor compound and the at least one other active substance are adminstered simultaneously, sequentially or separately.
    Type: Application
    Filed: August 5, 2016
    Publication date: June 29, 2017
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT inhibitors for the treatment of liver diseases
    Patent number: 9688720
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: June 27, 2017
    Assignee: Albireo AB
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT INHIBITORS FOR THE TREATMENT OF LIVER DISEASES
    Publication number: 20160194353
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Application
    Filed: March 14, 2016
    Publication date: July 7, 2016
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT INHIBITORS FOR THE TREATMENT OF LIVER DISEASES
    Publication number: 20160193277
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Application
    Filed: March 14, 2016
    Publication date: July 7, 2016
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT INHIBITORS FOR THE TREATMENT OF LIVER DISEASES
    Publication number: 20150031636
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Application
    Filed: October 3, 2014
    Publication date: January 29, 2015
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • PHARMACEUTICAL COMBINATION COMPRISING AN IBAT INHIBITOR AND A BILE ACID BINDER
    Publication number: 20150031637
    Abstract: The present invention relates to a combination comprising a substance with inhibiting effect on the ileal bile acid transport system (IBAT) and at least one other active substance selected from an IBAT inhibitor; an enteroendocrine peptide or enhancer thereof; a dipeptidyl peptidase-IV inhibitor; a biguanidine; an incretin mimetic; a thiazolidinone; a PPAR agonist; a HMG Co-A reductase inhibitor; a bile acid binder; and a TGR5 receptor modulator; wherein the IBAT inhibitor compound and the at least one other active substance are administered simultaneously, sequentially or separately.
    Type: Application
    Filed: October 3, 2014
    Publication date: January 29, 2015
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • PHARMACEUTICAL COMBINATION COMPRISING AN IBAT INHIBITOR AND A BILE ACID BINDER
    Publication number: 20130236541
    Abstract: The present invention relates to a combination comprising a substance with inhibiting effect on the ileal bile acid transport system (I BAT) and at least one other active substance selected from an IBAT inhibitor; an enteroendocrine peptide or enhancer thereof; a dipeptidyl peptidase-IV inhibitor; a biguanidine; an incretin mimetic; a thiazolidinone; a PPAR agonist; a HMG Co-A reductase inhibitor; a bile acid binder; and a TGR5 receptor modulator; wherein the IBAT inhibitor compound and the at least one other active substance are administered simultaneously, sequentially or separately.
    Type: Application
    Filed: November 8, 2011
    Publication date: September 12, 2013
    Applicant: Albireo AB
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT INHIBITORS FOR THE TREATMENT OF LIVER DISEASES
    Publication number: 20130225511
    Abstract: The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Application
    Filed: November 8, 2011
    Publication date: August 29, 2013
    Inventors: Per-Göran Gillberg, Hans Graffner, Ingemar Starke
  • IBAT INHIBITORS FOR TREATMENT OF METABOLIC DISORDERS AND RELATED CONDITIONS
    Publication number: 20120114588
    Abstract: The present invention regards specific IBAT inhibitors with improved effect in prophylaxis and treatment of metabolic syndrome, obesity, disorders of fatty acid metabolism, glucose utilization disorders, disorders in which insulin resistance is involved, diabetes mellitus, type 1 and type 2 diabetes. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
    Type: Application
    Filed: May 26, 2011
    Publication date: May 10, 2012
    Applicant: ALBIREO AB
    Inventors: Ingemar Starke, Hans Graffner, Per-Göran Gillberg, Ann-Margret Lindqvist, Bo Angelin
  • Benzothiazepine derivatives
    Patent number: 8067584
    Abstract: Compounds of formula: (1) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: February 23, 2004
    Date of Patent: November 29, 2011
    Assignee: Albireo AB
    Inventors: Ingemar Starke, Suzanne Alenfalk, Mats Peter Nordberg, Mikael Ulf Johan Dahlstrom, Stig Jonas Bostrom, Malin Anita Lemurell, Andreas Christer Wallberg
  • 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
    Patent number: 7906502
    Abstract: Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: March 15, 2011
    Assignee: AstraZeneca AB
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Ingemar Starke
  • 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
    Patent number: 7893048
    Abstract: Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: February 22, 2011
    Assignee: AstraZeneca AB
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ingemar Starke
  • Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity
    Patent number: 7871998
    Abstract: Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: January 18, 2011
    Assignee: AstraZeneca AB
    Inventors: Susanne Alenfalk, Mikael Dahlström, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ann-Margret Lindqvist, Tore Skjäret, Ingemar Starke