Patents by Inventor Ingemar Starke

Ingemar Starke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diphenylazetidinone Derivatives Possessing Cholesterol Absorption Inhibitory Activity
    Publication number: 20100099657
    Abstract: Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: November 16, 2006
    Publication date: April 22, 2010
    Applicant: AstraZeneca AB
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ann-Margret Lindqvist, Tore Skjaret, Ingemar Starke
  • New 2-Azetidinone Derivatives Useful In The Treatment Of Hyperlipidaemic Conditions
    Publication number: 20100048529
    Abstract: The invention relates to compounds of formula (I) and pharmaceutically acceptable salts, solvates, and prodrugs thereof, and to their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia. The invention also relates to processes for their manufacture and pharmaceutical compositions containing them.
    Type: Application
    Filed: June 21, 2006
    Publication date: February 25, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Mikael Dahlstrom, Staffan Karlsson, Malin Lemurell, Peter Nordberg, Ingemar Starke
  • New 2-Azetidinone Derivatives As Cholesterol Absorption Inhibitors For The Treatment Of Hyperlipidaemic Conditions
    Publication number: 20100048530
    Abstract: The invention relates to 2-azetidinone derivatives of formula (I), including pharmaceutically acceptable salts, solvates and prodrugs thereof. The compounds inhibit cholesterol absorption and are useful in the treatment of hyperlipidaemic conditions. The invention also relates to processes for their manufacture and to pharmaceutical compositions containing them.
    Type: Application
    Filed: June 21, 2006
    Publication date: February 25, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Mikael Dahlstrom, Staffan Karlsson, Peter Nordberg, Tore Skjaret, Ingemar Starke
  • 5,7-Disubstituted[1,3]Thiazolo[4,5-D]Pyrimidin-2(3H)-One Derivatives 258
    Publication number: 20090247555
    Abstract: There are disclosed novel 5,7-disubstituted [1,3]thiazolo[4,5-d]pyrimidin-2(3H)-one derivatives of formula (I) wherein R1, R2, R3, R4, R5, R6, and R7 are as defined in the specification, and pharmaceutically acceptable salts thereof, together with processes for their preparation, pharmaceutical compositions comprising them and their use in therapy. The compounds of formula (I) are CX3CR1 receptor antagonists and are thereby particularly useful in the treatment or prophylaxis of neurodegenerative disorders, demyelinating disease, cardio- and cerebrovascular atherosclerotic disorders, peripheral artery disease, rheumatoid arthritis, is pulmonary diseases such as COPD, asthma or pain.
    Type: Application
    Filed: March 26, 2009
    Publication date: October 1, 2009
    Applicant: AstraZeneca AB
    Inventors: Mikael Dahlstrom, Gunnar Nordvall, Tobias Rein, Ingemar Starke
  • Diphenylazetidinone Derivatives Possessing Cholesterol Absorption Inhibitor Activity
    Publication number: 20090069285
    Abstract: 2-azetidinone derivatives and pharmaceutical compositions containing them. The compounds are useful in the treatment of hyperlipidemic conditions, atherosclerosis, Alzheimers' disease and cholesterol associated tumours.
    Type: Application
    Filed: April 25, 2007
    Publication date: March 12, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Malin Lemurell, Ingemar Starke
  • Diphenylazetidinone derivatives for treating disorders of the lipid metabolism
    Patent number: 7470678
    Abstract: Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: December 30, 2008
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, Ann-Margret Lindqvist, Mats Peter Nordberg, Tore Skjaret, Malin Anita Lemurell
  • Diphenylazetidinone Derivatives Possessing Cholesterol Absorption Inhibitory Activity
    Publication number: 20080064676
    Abstract: Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: December 21, 2004
    Publication date: March 13, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ann-Margret Lindqvist, Tore Skjaret, Ingemar Starke
  • Benzothiadiazepine derivatives, processes for their preparation and pharmaceutical compositions containing them
    Patent number: 7238684
    Abstract: The present invention relates to compounds of formula (I): wherein Rv, R1, R2, Rx, Ry, R3, R4, R5, R6, Rz and v are as defined within; pharmaceutically acceptable salts, solvates, solvates or such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: April 23, 2003
    Date of Patent: July 3, 2007
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, Mats Peter Nordberg, Suzanne Alenfalk, Andreas Christer Wallberg, Stig Jonas Bostrom
  • Diphenylazetidinone derivatives possessing chloesterol absorption inhibitory activity
    Publication number: 20070142304
    Abstract: Compounds of formula (XV): [Chemical formula should be inserted here. Please see paper copy] (XV) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: December 21, 2004
    Publication date: June 21, 2007
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ann-Margret Lindqvist, Tore Skjaret, Ingemar Starke
  • Benzothiepine ileal bile acid transport inhibitors
    Patent number: 7226943
    Abstract: The present invention relates to compounds of formula (I) wherein variable groups are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: June 5, 2007
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, David Blomberg
  • Benzothiazepine derivatives
    Patent number: 7192946
    Abstract: The present invention relates to compounds of formula (I), wherein variable groups are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: March 20, 2007
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, David Blomberg, Suzanne Alenfalk, Peter Nordberg, Andreas Christer Wallberg, Stig Jonas Bostrom
  • Benzothiazepine derivatives
    Patent number: 7192945
    Abstract: The present invention relates to compounds of the formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: March 20, 2007
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Dahlstrom, David Blomberg
  • Peptides derivatives comprising thiazepine group for the treatment of hyperlipidemic conditions
    Patent number: 7192947
    Abstract: The present invention relates to compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia.
    Type: Grant
    Filed: June 10, 2003
    Date of Patent: March 20, 2007
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, Suzanne Alenfalk, Tore Skjaret, Malin Lemurell
  • Benzothiazepine and benzothiazepine derivatives with ileal bile acid transport (IBAT) inhibotory activity for the treatment hyperlipidaemia
    Patent number: 7132416
    Abstract: The present invention relates to compounds of formula (I) wherein Rv, R1, R2, Rx, Ry, M, Rz, v, R3, R4, R5 and R6 are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: November 7, 2006
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, David Blomberg, Suzanne Alenfalk, Tore Skjaret, Malin Lemurell
  • Benzothiazepine derivatives for the treatment of hyperlipidemia
    Patent number: 7125864
    Abstract: The present invention relates to compounds of formula (I): wherein variable groups are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidemia.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: October 24, 2006
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, David Blomberg
  • Benzothiazepine and benzothiepine derivatives
    Publication number: 20060094884
    Abstract: Compounds of formula: (1) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: February 23, 2004
    Publication date: May 4, 2006
    Inventors: Ingemar Starke, Suzanne Alenfalk, Mats Nordberg, Mikael Dahlstrom, Stig Bostrom, Malin Lemurell, Andreas Wallberg
  • Diphenylazetidinone derivatives for treating disorders of the lipid metabolism
    Publication number: 20050239766
    Abstract: Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: July 1, 2003
    Publication date: October 27, 2005
    Applicant: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Dahlstrom, Ann-Margret Lindqvist, Mats Nordberg, Tore Skjaret, Malin Lemurell
  • Peptides derivatives comprising thiazepine group for the treatment of hyperlipidermic conditions
    Publication number: 20050222120
    Abstract: The present invention relates to compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Process for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: June 10, 2003
    Publication date: October 6, 2005
    Inventors: Ingemar Starke, Mikael Dahlstrom, Suzanne Alenfalk, Tore Skjaret, Malin Lemurell
  • New compounds
    Publication number: 20050154007
    Abstract: The present invention relates to novel compounds, and therapeutically acceptable salts thereof of the formula (I), which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.
    Type: Application
    Filed: June 30, 2004
    Publication date: July 14, 2005
    Inventors: Kosrat Amin, Mikael Dahlstrom, Peter Nordberg, Ingemar Starke
  • Chemical compounds
    Publication number: 20050143368
    Abstract: The present invention relates to compounds of formula (1): wherein Rv, R1, R2, Rx, Ry, R3, R4, R5, R6, Rz and v are as defined within; pharmaceutically acceptable salts, solvates, solvates or such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: April 23, 2003
    Publication date: June 30, 2005
    Inventors: Ingemar Starke, Mikael, Ulf, Johan Dahlstrom, Mats, Peter Nordberg, Suzanne Alenfalk, Andreas, Christer Wallberg, Stig, Jonas Bostrom