Abstract: Estrogenic compounds and compositions, and a method, are presented. The novel estrogenic compounds comprise novel chalcone derivatives and analogs that have little or no measurable estrogen (estradiol, E2) activity but potentiate E2 activity without binding an estrogen receptor (ER). The novel compositions comprise one or more of the novel estrogenic compounds and may optionally comprise one or more excipients. The one or more excipients may be pharmaceutically acceptable. The one or more excipients may comprise at least one compound that does not occur in nature with estrogenic compounds. The method comprises administering a pharmaceutical composition comprising an estrogenic compound described herein to a patient in need of treatment with an estrogenic compound or pharmaceutical composition.

Abstract: Estrogenic compounds, combinations, pharmaceutical compositions and methods are presented. The estrogenic compounds comprise ER?-selective estrogenic compounds and combinations thereof. The novel compositions comprise one or more of the ER?-selective estrogenic compounds, and may optionally comprise one or more excipients. The one or more excipients may be pharmaceutically acceptable. The one or more excipients may comprise at least one compound that does not occur in nature with estrogenic compounds. The method comprises administering a pharmaceutical composition comprising an estrogenic compound described herein to a patient in need of treatment with an estrogenic compound or combination, or a pharmaceutical composition comprising the estrogenic compound or combination.

Abstract: A bridgeless power factor correction (PFC) control circuit includes a non-linear current sensor. The non-linear current sensor includes a non-linear shunt, a comparator, and a reference voltage circuit. The non-linear shunt includes a capacitor connection terminal and a ground terminal. The comparator includes a first input, a reference voltage input, and a zero-crossing detector output. The first is input coupled to the capacitor connection terminal. The reference voltage circuit is coupled to the reference voltage input.

Abstract: A programmable switch converter controller for a power stage with a switch, an inductor, and a diode, includes a pulse-width modulator. The pulse-width modulator is configured to: generate an on-time interval (Ton) that is fixed or proportional to a demand signal proportional to a load adapted to be coupled to an output of the power stage; generate an off-time interval (Toff) that is inversely proportional to the product of a voltage across the inductor while the switch is off and a demand signal proportional to the load; initiate Ton when Toff elapses; and initiate Ton responsive to an external trigger signal.

Abstract: A voltage converter, including an input adapted to couple to a voltage source and a transformer including a primary coil and a secondary coil. Primary side circuitry, including a first switching circuit, is coupled to the primary coil. A second switching circuit is coupled between a first terminal and a second terminal of the secondary coil, and configured to selectively close to short circuit the first terminal to the second terminal.

Abstract: In an example, a current estimating circuit includes a current estimating resistor coupled in series with a current estimating capacitor. The current estimating resistor and the current estimating capacitor are configured to provide a voltage across the current estimating capacitor during a first portion of a switching cycle, in which the voltage across the current estimating capacitor is proportional to an inductor current that flows through an inductor. The current estimating circuit includes a sense resistor configured to provide a sensed voltage across the sense resistor during a second portion of the switching cycle. The current estimating circuit includes a switch configured to apply the sensed voltage to the current estimating capacitor to provide the voltage across the current estimating capacitor during the second portion of the switching cycle.

Abstract: A programmable switch converter controller for a power stage with a switch, an inductor, and a diode, includes a pulse-width modulator. The pulse-width modulator is configured to: generate an on-time interval (Ton) that is fixed or proportional to a demand signal proportional to a load adapted to be coupled to an output of the power stage; generate an off-time interval (Toff) that is inversely proportional to the product of a voltage across the inductor while the switch is off and a demand signal proportional to the load; initiate Ton when Toff elapses; and initiate Ton responsive to an external trigger signal.

Abstract: The technology disclosed relates to creating user-defined interaction spaces and modalities in a three dimensional (3D) sensor space in response to control gestures. It also relates to controlling virtual cameras in the 3D sensor space using control gestures and manipulating controls of the virtual cameras through the control gestures. In particular, it relates to defining one or more spatial attributes of the interaction spaces and modalities in response to one or more gesture parameters of the control gesture. It also particularly relates to defining one or more visual parameters of a virtual camera in response to one or more gesture parameters of the control gesture.

Abstract: The technology disclosed relates to automatically interpreting motion of a control object in a three dimensional (3D) sensor space by sensing a movement of the control object in the (3D) sensor space, interpreting movement of the control object, and presenting the interpreted movement as a path on a display. The path may be displayed once the speed of the movement exceeds a pre-determined threshold measured in cm per second. Once the path is displayed, the technology duplicates a display object that intersects the path on the display. In some implementations, the control object may be a device, a hand, or a portion of a hand (such as a finger).

Abstract: The technology disclosed relates to creating user-defined interaction spaces and modalities in a three dimensional (3D) sensor space in response to control gestures. It also relates to controlling virtual cameras in the 3D sensor space using control gestures and manipulating controls of the virtual cameras through the control gestures. In particular, it relates to defining one or more spatial attributes of the interaction spaces and modalities in response to one or more gesture parameters of the control gesture. It also particularly relates to defining one or more visual parameters of a virtual camera in response to one or more gesture parameters of the control gesture.

Abstract: A circuit includes a switching stage including a primary switch and an input controller. The input controller activates the primary switch to conduct a primary current in a primary winding of a transformer in response to a zero amplitude of a switch voltage at a switching terminal, and can deactivate the primary switch to provide a secondary current in a secondary winding of the transformer based on the primary current. The circuit also includes an output stage that provides an output voltage in response to the secondary current. The output stage includes a secondary switch and an output controller. The output controller activates the secondary switch to conduct a request current in the secondary winding in response to ringing of a primary voltage across the primary winding and the output voltage, and deactivates the secondary switch to provide the reflected current in the primary winding based on the request current.

Abstract: An example apparatus includes: a first diode having a first diode terminal; a transformer having a transformer terminal; a second diode having a second diode terminal and a third diode terminal, the second diode terminal coupled to the transformer terminal; a first switch having a first current terminal and a second current terminal, the first current terminal coupled to the first diode terminal, the second current terminal coupled to the third diode terminal; a second switch having a third current terminal, the third current terminal coupled to the second diode terminal and the transformer terminal; a capacitor having a first capacitor terminal and a second capacitor terminal, the first capacitor terminal coupled to the second current terminal; and a third diode having a fourth diode terminal and a fifth diode terminal, the fourth diode terminal coupled to the first capacitor terminal, the fifth diode terminal coupled to the capacitor.

Abstract: In an example, a current estimating circuit includes a current estimating resistor coupled in series with a current estimating capacitor. The current estimating resistor and the current estimating capacitor are configured to provide a voltage across the current estimating capacitor during a first portion of a switching cycle, in which the voltage across the current estimating capacitor is proportional to an inductor current that flows through an inductor. The current estimating circuit includes a sense resistor configured to provide a sensed voltage across the sense resistor during a second portion of the switching cycle. The current estimating circuit includes a switch configured to apply the sensed voltage to the current estimating capacitor to provide the voltage across the current estimating capacitor during the second portion of the switching cycle.

Abstract: An example circuit includes a first transistor and a second transistor coupled in series with the first transistor. A regulator circuit is configured to regulate a voltage across the second transistor based on a first reference voltage and a voltage at a node between the first and second transistors. A rectification drive circuit is configured to operate the first and second transistors in a rectification mode based on a voltage at the node and at least one second reference voltage.

Abstract: In a described example, a switching controller can be configured to activate a first rectifier switch of an output stage of a power supply system in a first state to provide a secondary current from a secondary winding of a first transformer to generate an output voltage at the output stage in response to detecting a first direction of a secondary current through a secondary winding of a second transformer. Additionally, the switching controller can be configured to activate a second rectifier switch of the output stage of the power supply system in a second state to provide the secondary current from the secondary winding of the first transformer to generate the output voltage at the output stage in response to detecting a second direction of the secondary current through the secondary winding of the second transformer.

Abstract: The techniques and circuits, described herein, include solutions for multimode current control for pulse width modulation (PWM) converters. In some aspects, a slope control circuit is used to simulate a current through an inductor during a discharging phase as a voltage across a switching capacitor. A slope-control voltage is used to modify the slope of the simulated current waveform relative to an actual inductor current waveform. Based on if a magnitude of the modified slope is greater than, less than, or equal to the actual slope, the converter may be selectively operated in continuous conduction mode (CCM), discontinuous conduction mode (DCM), or transition mode (TM) respectively.

Abstract: In described examples, a circuit includes a voltage sensor that has an output, first and second transconductance amplifiers, first and second switches, a capacitive element, a comparator, and a sampling circuit. Each of the first and second transconductance amplifiers has a respective input, a respective output, and a respective transconductance. The first switch is coupled between the voltage sensor output and the first transconductance amplifier input. The second switch is coupled between the voltage sensor output and the second transconductance amplifier input. The capacitive element has a first terminal coupled to the respective outputs of the first and second transconductance amplifiers. The comparator has a respective input and a respective output. The comparator input is coupled to the respective outputs of the first and second transconductance amplifiers and to the first terminal of the capacitive element. The sampling circuit is coupled to the output of the comparator.

Abstract: The technology disclosed relates to automatically interpreting motion of a control object in a three dimensional (3D) sensor space by sensing a movement of the control object in the (3D) sensor space, interpreting movement of the control object, and presenting the interpreted movement as a path on a display. The path may be displayed once the speed of the movement exceeds a pre-determined threshold measured in cm per second. Once the path is displayed, the technology duplicates a display object that intersects the path on the display. In some implementations, the control object may be a device, a hand, or a portion of a hand (such as a finger).

Abstract: The technology disclosed relates to creating user-defined interaction spaces and modalities in a three dimensional (3D) sensor space in response to control gestures. It also relates to controlling virtual cameras in the 3D sensor space using control gestures and manipulating controls of the virtual cameras through the control gestures. In particular, it relates to defining one or more spatial attributes of the interaction spaces and modalities in response to one or more gesture parameters of the control gesture. It also particularly relates to defining one or more visual parameters of a virtual camera in response to one or more gesture parameters of the control gesture.