Patents by Inventor J. Clarke

J. Clarke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SPARK GAP STRUCTURES FOR DETECTION AND PROTECTION AGAINST ELECTRICAL OVERSTRESS EVENTS
    Publication number: 20190293692
    Abstract: The disclosed technology generally relates to electrical overstress protection devices, and more particularly to electrical overstress monitoring devices for detecting electrical overstress events in semiconductor devices. In one aspect, an electrical overstress monitor and/or protection device includes a two different conductive structures configured to electrically arc in response to an EOS event and a sensing circuit configured to detect a change in a physical property of the two conductive structures caused by the EOS event.
    Type: Application
    Filed: March 21, 2019
    Publication date: September 26, 2019
    Inventors: David J. Clarke, Stephen Denis Heffernan, Nijun Wei, Alan J. O'Donnell, Patrick Martin McGuinness, Shaun Bradley, Edward John Coyne, David Aherne, David M. Boland
  • FLUID FLOW CONTROL BY A NON-PINCHING VALVE
    Publication number: 20190282798
    Abstract: A pumping system comprising a pump comprising a door for access within a housing of the pump, a pump segment configured for conveying a fluid based on compression of the pump segment, a pump segment frame for preventing said pump segment from stretching, a visual placement indicator configured for facilitating in a proper placement of the pump segment frame in the housing, and a non-pinching valve configured to be disposed in the housing and to control a flow of the fluid without requiring pinching of a tube.
    Type: Application
    Filed: May 31, 2019
    Publication date: September 19, 2019
    Inventors: George MANSOUR, Chris ZOLLINGER, Jonathan YEH, Christopher J. CLARKE
  • METHODS FOR DETECTING DNA MUTATIONS USING MITRA TIP EXTRACTION
    Publication number: 20190284639
    Abstract: The present disclosure provides rapid and non-invasive methods for determining whether a patient exhibiting cancer symptoms, or at risk for hereditary cancers such as breast cancer, ovarian cancer, colon cancer, or skin cancer, will benefit from treatment with one or more therapeutic agents. These methods are based on detecting hereditary cancer-related mutations in small-volume dried biological fluid samples that are collected using a volumetric absorptive microsampling device (e.g., MITRA Tip). Kits for use in practicing the methods are also provided.
    Type: Application
    Filed: November 13, 2017
    Publication date: September 19, 2019
    Applicant: Quest Diagnostics Investments LLC
    Inventors: Heather Sanders, Nigel J. Clarke
  • METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS
    Publication number: 20190276904
    Abstract: The present disclosure provides rapid and non-invasive methods for determining whether a patient will benefit from treatment with therapeutic agents that inhibit Hepatitis C virus (HCV). These methods are based on detecting HCV RNA and/or anti-HCV antibodies in small-volume dried biological fluid samples that are collected using a microsampling device. Kits for use in practicing the methods are also provided.
    Type: Application
    Filed: November 13, 2017
    Publication date: September 12, 2019
    Applicant: Quest Diagnostics Investments LLC
    Inventors: Amy Rogers, John Leake, Nigel J. Clarke, Russell E. Baumann
  • METHODS FOR DETECTING VITAMIN D METABOLITES BY MASS SPECTROMETRY
    Publication number: 20190250175
    Abstract: Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally directed to ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay.
    Type: Application
    Filed: April 22, 2019
    Publication date: August 15, 2019
    Inventors: Nigel J. Clarke, Brett Holmquist, Gloria Kwang-Ja Lee, Richard E. Reitz
  • Enhanced policy editor with completion support and on demand validation
    Patent number: 10372583
    Abstract: In an approach to providing completion support and on demand validation in a web tool that operates on live resources, one or more computer processors create one or more lists of content, where the one or more lists of content include one or more references to one or more runtime objects. The one or more computer processors parse the one or more lists of content. The one or more computer processors populate one or more lists of one or more choices with the parsed one or more lists of content. The one or more computer processors create one or more callbacks for one or more runtime objects referenced by the one or more lists of one or more choices.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: August 6, 2019
    Assignee: International Business Machines Corporation
    Inventors: Matthew J. Clarke, Doina L. Klinger
  • Wear-out monitor device
    Patent number: 10365322
    Abstract: The disclosed technology generally relates to integrated circuit devices with wear out monitoring capability. An integrated circuit device includes a wear-out monitor device configured to record an indication of wear-out of a core circuit separated from the wear-out monitor device, wherein the indication is associated with localized diffusion of a diffusant within the wear-out monitor device in response to a wear-out stress that causes the wear-out of the core circuit.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: July 30, 2019
    Assignee: ANALOG DEVICES GLOBAL
    Inventors: Edward John Coyne, Alan J. O'Donnell, Shaun Bradley, David Aherne, David Boland, Thomas G. O'Dwyer, Colm Patrick Heffernan, Kevin B. Manning, Mark Forde, David J. Clarke, Michael A. Looby
  • Vapor sheath for liquid dispensing nozzle
    Patent number: 10357798
    Abstract: The present disclosure provides a device for preventing the fouling of a liquid dispensing nozzle. The end of the dispensing nozzle is placed in a hollow interior of a band carrying the same solvent that is dispensed by the nozzle. The solvent on the band evaporates into a gap between the band and the dispensing nozzle, thus providing a vapor sheath, or environment in the gap, that helps to prevent the fouling of the dispensing nozzle.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: July 23, 2019
    Assignee: GLAXOSMITHKLINE LLC
    Inventors: Allan J. Clarke, Frederick H. Fiesser, James A. McHugh
  • Fluid flow control by a non-pinching valve
    Patent number: 10350402
    Abstract: A pumping system comprising a pump comprising a door for access within a housing of the pump, a pump segment configured for conveying a fluid based on compression of the pump segment, a pump segment frame for preventing said pump segment from stretching, a visual placement indicator configured for facilitating in a proper placement of the pump segment frame in the housing, and a non-pinching valve configured to be disposed in the housing and to control a flow of the fluid without requiring pinching of a tube.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: July 16, 2019
    Assignee: CAREFUSION 303, INC.
    Inventors: George Mansour, Chris Zollinger, Jonathan Yeh, Christopher J. Clarke
  • Wear-out monitor device
    Patent number: 10338132
    Abstract: The disclosed technology generally relates to integrated circuit devices with wear out monitoring. An integrated circuit device includes a core circuit and a wear-out monitor device. The wear-out monitor device configured to adjust an indication of wear out of the core circuit regardless of whether the core circuit is activated The integrated circuit further includes a sensing circuit coupled to the wear-out monitor device and configured to detect an electrical property of the wear-out monitor device that is indicative of a wear-out level of the core-circuit.
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: July 2, 2019
    Assignee: Analog Devices Global
    Inventors: Edward John Coyne, Alan J. O'Donnell, Colm Patrick Heffernan, Kevin B. Manning, Mark Forde, David J. Clarke, Thomas G. O'Dwyer, David Aherne, Michael A. Looby
  • STEM-CyLE: SCIENCE TECHNOLOGY ENGINEERING AND MATHEMATICS CYBERLEARNING ENVIRONMENT
    Publication number: 20190189021
    Abstract: Systems and method are provided for educational content and learning management systems. A system can include a computer-readable storage medium, a graphical user interface, an application programming interface, a communication link for connecting the computer-readable to at least one computing device. The medium can have instructions stored thereon and including learning objects, course materials, educational tutorials, virtual problem-based environments, and gamification elements.
    Type: Application
    Filed: December 19, 2017
    Publication date: June 20, 2019
    Applicant: The Florida International University Board of Trustees
    Inventors: Peter J. Clarke, Raymond Chang Lau, Steve Foo, Debra Davis
  • Thyroglobulin quantitation by mass spectrometry
    Patent number: 10309971
    Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: June 4, 2019
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Yanni Zhang, Nigel J. Clarke, Richard E. Reitz
  • Car enzymes and improved production of fatty alcohols
    Patent number: 10301603
    Abstract: The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: May 28, 2019
    Assignee: Reg Life Sciences, LLC
    Inventors: Derek L. Greenfield, Elizabeth J. Clarke, Eli S. Groban, Vikranth Arlagadda, Sungwon Lee, Xuezhi Li, Zhihao Hu, Baolong Zhu
  • THYROGLOBULIN QUANTITATION BY MASS SPECTROSCOPY
    Publication number: 20190145984
    Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.
    Type: Application
    Filed: January 28, 2019
    Publication date: May 16, 2019
    Inventors: Yanni Zhang, Nigel J. Clarke, Richard E. Reitz
  • Displaying colours on an electronic visual display
    Patent number: 10290280
    Abstract: The present invention relates to a method of displaying colors on an electronic visual display. The colors correspond to a principal color and one or more auxiliary colors each of which is defined by color co-ordinates within a color space. When one or more of the colors is out of the gamut of the display, adjustments are made to the co-ordinates of each color to allow adjusted colors to be displayed that preserve the color differences between the principal color and each of the one or more auxiliary colors.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: May 14, 2019
    Assignee: TINTOMETER GMBH
    Inventors: Nicholas J. Barnes, Peter J. Clarke
  • ELECTRICAL OVERSTRESS REPORTING
    Publication number: 20190128939
    Abstract: Aspects of this disclosure relate to detecting and recording information associated with electrical overstress (EOS) events, such as electrostatic discharge (ESD) events. For example, in one embodiment, an apparatus includes an electrical overstress protection device, a detection circuit configured to detect an occurrence of the EOS event, and a memory configured to store information indicative of the EOS event.
    Type: Application
    Filed: November 1, 2017
    Publication date: May 2, 2019
    Inventors: Alan J. O'Donnell, David Aherne, Javier Alejandro Salcedo, David J. Clarke, John A. Cleary, Patrick Martin McGuinness, Albert C. O'Grady
  • Methods for detecting vitamin D metabolites by mass spectrometry
    Patent number: 10267810
    Abstract: Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally directed to ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: April 23, 2019
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Nigel J. Clarke, Brett Holmquist, Gloria Kwang-Ja Lee, Richard E. Reitz
  • Automating inventory management of consumer items
    Patent number: 10204313
    Abstract: A method and system for automating the management of an inventory of consumer items at a consumer location uses a programmed device that accepts input data and executes control logic for automating inventory management. At least one shopping list is received, a shopping list trend is established, and a smart list is generated with the control logic, in accordance with the shopping list trend, such that the smart list predictive of a next shopping list.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: February 12, 2019
    Assignee: Comcast Cable Communications, LLC
    Inventors: J. Clarke Stevens, Carol L. Stimmel
  • DISPLAYING COLOURS ON AN ELECTRONIC VISUAL DISPLAY
    Publication number: 20190035359
    Abstract: The present invention relates to a method of displaying colours on an electronic visual display. The colours correspond to a principal colour and one or more auxiliary colours each of which is defined by colour co-ordinates within a colour space. When one or more of the colours is out of the gamut of the display, adjustments are made to the co-ordinates of each colour to allow adjusted colours to be displayed that preserve the colour differences between the principal colour and each of the one or more auxiliary colours.
    Type: Application
    Filed: January 27, 2017
    Publication date: January 31, 2019
    Applicant: Tintometer GmbH
    Inventors: Nicholas J. BARNES, Peter J. CLARKE
  • Thyroglobulin quantitation by mass spectroscopy
    Patent number: 10191064
    Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: January 29, 2019
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Yanni Zhang, Nigel J. Clarke, Richard E. Reitz