Abstract: Systems and methods for screening applicants are disclosed herein. A method of screening applicants is performed by a screening server. The server begins by receiving a selection of screening services and an applicant profile that identifies an applicant. The screening continues by generating screening results specified by the selection of screening services based on the applicant profile. A property manager is then notified that the screening results are available for the applicant based upon the applicant profile. The screening results are then provided to the property manager based upon the applicant profile. Based on these screening results, the screener or property manager can make a decision about the applicant and communicate a decision action to the applicant.

Abstract: Ophthalmic lenses incorporate multifocal properties for the purpose of slowing, retarding, controlling or preventing myopia development or progression, correcting presbyopic vision or allowing extended depth of focus. The lens has electronically controlled adjustable focus where the change in focus oscillates so rapidly that it is imperceptible to human vision.

Abstract: A power system includes a first power input, a second power input, a power output, a first ideal diode coupled to the a power input and a power output and a second ideal diode coupled to a second power input and the power output. The power system also includes a first switching circuit coupled to the first power input and the first ideal diode and a second switching circuit coupled to the second power input and the second ideal diode, the switching circuits operating as an open or a short circuit based on an input. The power system also includes a test controller coupled to the first switching circuit, the second switching circuit and the power output and configured to determine an operating status of the power system based on an input to the first switch, inputs to the second switch and the power output.

Abstract: An IOL includes a fluid optic body having a cavity defined by a sidewall, a deformable optical membrane intersecting the sidewall around an anterior circumference of the sidewall, and a posterior optic intersecting the sidewall around a posterior circumference of the sidewall. The posterior optic includes a central protrusion extending anteriorly into the cavity and the deformable optical membrane includes a ring-shaped protrusion extending posteriorly into a space between the sidewall and the central protrusion. A second optic body is spaced apart from the fluid optic body and coupled thereto via a plurality of struts. Axial compression causes the plurality of struts to deform the sidewall in a manner that increases the diameter of the cavity, modifying a curvature of the deformable optical membrane is modified. Contact between the ring-shaped protrusion and the central protrusion defines a maximum modification to the curvature of the deformable optical membrane.

Abstract: Described herein are novel biological converter switches that utilize modular components, such as genetic toggle switches and single invertase memory modules (SIMMs), for converting analog inputs to digital outputs, and digital inputs to analog outputs, in cells and cellular systems. Flexibility in these biological converter switches is provided by combining individual modular components, i.e., SIMMs and genetic toggle switches, together. These biological converter switches can be combined in a variety of network topologies to create circuits that act, for example, as switchboards, and regulate the production of an output product(s) based on the combination and nature of input signals received.

Abstract: The present invention provides methods and systems for real-time measurements of PCR with multiplexing capability. Certain embodiments relate to methods and systems that use fluorescently encoded superparamagnetic microspheres for the immobilization of amplification products during the PCR process, and an imaging chamber of a measurement device that is also capable of controllable thermal cycling for assisting the PCR process.

Abstract: Disclosed herein is a cooling pad for use in bringing down the increased temperature of a hyper-thermic patient. The cooling pad could be adapted in the form of a mattress or could be used to cover the body of hyperthermic patient. The cooling pad comprises a flexible and rollable sealed elongated envelope made of multiple layers. The inner layer of envelope is fluid impervious, followed by a protective outer layer. The envelope encloses a fluid having high latent heat of fusion and may further include additives such as viscosity modifying agent.

Abstract: A permanent magnet alternator (PMA) includes a rotatable shaft, windings, a shunt regulator circuit, and a speed detection circuit. The rotatable shaft is connected electromagnetically to the windings. The shunt regulator circuit is electrically connected to the windings. A current sense transformer with a primary coil is electrically connected to the shunt regulator circuit. A secondary coil is electrically connected to a comparator circuit with reference voltage and generates voltage pulse indicating PMA speed. The voltage pulses form an output corresponding to and indicative of rotation speed of the shaft suitable for processing by a processor to present a PMA speed indication for use in the overall system architecture as a measurement parameter.

Abstract: The methods and compositions described herein relate, in part, to the generation of a synthetic degradation system in E. coli that provides tunable control of the protein level of targeted genes by using components of the Mesoplasma florum tmRNA system. Provided herein are degradation tag variants that permit independent control of both the initial level and inducible degradation rate of attached proteins.

Abstract: The invention provides novel and versatile classes of riboregulators, including inter alia activating and repressing riboregulators, switches, and trigger and sink RNA, and methods of their use for detecting RNAs in a sample such as a well and in modulating protein synthesis and expression.

Abstract: Systems and methods for screening applicants are disclosed herein. A method of screening applicants is performed by a screening server. The server begins by receiving a selection of screening services and an applicant profile that identifies an applicant. The screening continues by generating screening results specified by the selection of screening services based on the applicant profile. A property manager is then notified that the screening results are available for the applicant based upon the applicant profile. The screening results are then provided to the property manager based upon the applicant profile. Based on these screening results, the screener or property manager can make a decision about the applicant and communicate a decision action to the applicant.

Abstract: Contact lenses incorporate high plus or add power profiles that at least one of slow, retard or preventing myopia progression and minimize halo effect. The lens includes a center zone with a negative power for myopic vision correction; and at least one treatment zone surrounding the center zone, the at least one treatment zone having a power profile that increases from an outer margin of the center zone to a positive power within the at least one treatment zone of greater than +5.00 D.

Abstract: Described herein are novel biological converter switches that utilize modular components, such as genetic toggle switches and single invertase memory modules (SIMMs), for converting analog inputs to digital outputs, and digital inputs to analog outputs, in cells and cellular systems. Flexibility in these biological converter switches is provided by combining individual modular components, i.e., SIMMs and genetic toggle switches, together. These biological converter switches can be combined in a variety of network topologies to create circuits that act, for example, as switchboards, and regulate the production of an output product(s) based on the combination and nature of input signals received.

Abstract: The invention provides novel and versatile classes of riboregulators, including inter alia activating and repressing riboregulators, switches, and trigger and sink RNA, and methods of their use for detecting RNAs in a sample such as a well and in modulating protein synthesis and expression.

Abstract: The present invention provides methods and systems for real-time measurements of PCR with multiplexing capability. Certain embodiments relate to methods and systems that use fluorescently encoded superparamagnetic microspheres for the immobilization of amplification products during the PCR process, and an imaging chamber of a measurement device that is also capable of controllable thermal cycling for assisting the PCR process.

Abstract: Lenses are designed using the corneal topography or wavefront measurements of the eye derived by subtracting the optical power of the eye after orthokeratology treatment from the optical power before orthokeratology treatment.

Abstract: A permanent magnet alternator (PMA) includes a rotatable shaft, windings, a shunt regulator circuit, and a speed detection circuit. The rotatable shaft is connected electromagnetically to the windings. The shunt regulator circuit is electrically connected to the windings. A current sense transformer with a primary coil is electrically connected to the shunt regulator circuit. A secondary coil is electrically connected to a comparator circuit with reference voltage and generates voltage pulse indicating PMA speed. The voltage pulses form an output corresponding to and indicative of rotation speed of the shaft suitable for processing by a processor to present a PMA speed indication for use in the overall system architecture as a measurement parameter.

Abstract: Methods and apparatus to automatically fabricate fillers are disclosed. An example method includes aligning rigid surface data with flexible surface data, the rigid surface data and the flexible surface data being permitted to overlap when aligned; when aligned, defining the rigid surface data and the flexible surface data based on a same parameter space; calculating a displacement function based on differences between corresponding ones of first points in the flexible surface data and second points in the rigid surface data; determining a modified position of a first one of the first points by modifying the first one of the first points based on a value of the displacement function; calculating a gap between the modified position of the first one of the first points and a second one of the second points; and creating a physical filler to fill a physical gap corresponding to the calculated gap.

Abstract: Disclosed aircraft wing-to-body join methods include (a) applying targets to a wing and a body assembly at the respective wing root and wing stub, (b) determining the 3D locations of the targets by photogrammetry, (c) generating 3D surface profiles for the interface surfaces of the wing root and wing stub by combining scans of the interface surfaces, (d) calculating a virtual fit between the wing and the body assembly that defines one or more gaps between the generated 3D surface profiles of the wing root and wing stub, (e) positioning at least three position sensors within the wing root and/or the wing stub, and (f) aligning the wing to the body assembly to achieve a real fit consistent with the calculated virtual fit using feedback from the position sensors. Methods of determining the target locations and/or the 3D surface profiles may utilize a mobile scanning platform.

Abstract: Provided herein are compositions and methods to improve treatment of chronic infections, and reduce, delay, or inhibit formation of biofilms, using specific combinations of aminoglycoside antibiotics and high, localized concentrations of one or more PMF stimulating compounds. These novel methods are easily adapted to clinical settings as toxicity and efficacy of the antibiotics and metabolites used have already been studied in vivo, and as dosing for both the antibiotics and metabolites are known. These approaches and therapeutic methods are also useful with non-metabolic chemicals that induce proton-motive force in bacteria.