Patents by Inventor J. Metcalf

J. Metcalf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7101963
    Abstract: The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia pneumoniae, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication process or in virulence, polypeptides encoded by such sequences, as well as vectors including the said sequences and cells or animals transformed with these vectors. The invention also relates to transcriptional gene products of the Chlamydia pneumoniae genome, such as, for example, antisense and ribozyme molecules, which can be used to control growth of the microorganism. The invention also relates to methods of detecting these nucleic acids or polypeptides and kits for diagnosing Chlamydia pneumoniae infection. The invention also relates to a method of selecting compounds capable of modulating bacterial infection and a method for the biosynthesis or biodegradation of molecules of interest using the said nucleotide sequences or the said polypeptides.
    Type: Grant
    Filed: November 7, 2002
    Date of Patent: September 5, 2006
    Assignee: Serono Genetica Institute S.A.
    Inventors: Rémy Griffais, Susan K. Hoiseth, Robert J. Zagursky, Benjamin J. Metcalf, Joel A. Peek, Banumathi Sankaran, Leah D. Fletcher
  • Patent number: 7102111
    Abstract: A folds-as-you-eat multi-purpose food-serving apparatus (‘MPFSA’) that is supportable from one end by one hand during eating, and has optional exhibiting means for providing multi-minute close-proximity exposures promoting observer-discernible content and/or user-discernible content, and optionally providing recreational, or display, functionality. The MPFSA is comprised of one or more materials having a pliability which accommodates the bending and unbending of the apparatus a plurality of times in a manner that will not significantly alter the presentation of served food. The MPFSA is also comprised of material(s) having sufficient rigidity to support one or more items of food, having a food-supporting surface which is stiffened by at least one adjacent food-retaining portion which extends upward from an edge thereof, or can be so positioned by a user, to increase the rigidity of, and facilitate the retention of served food on, the apparatus.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: September 5, 2006
    Inventors: Darrell J. Metcalf, Michael Goodrow
  • Patent number: 7041490
    Abstract: The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia trachomatis, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication process or in virulence, polypeptides encoded by such sequences, as well as vectors including the said sequences and cells or animals transformed with these vectors. The invention also relates to transcriptional gene products of the Chlamydia trachomatis genome, such as, for example, antisense and ribozyme molecules, which can be used to control growth of the microorganism. The invention also relates to methods of detecting these nucleic acids or polypeptides and kits for diagnosing Chlamydia trachomatis infection. The invention also relates to a method of selecting compounds capable of modulating bacterial infection and a method for the biosynthesis or biodegradation of molecules of interest using the said nucleotide sequences or the said polypeptides.
    Type: Grant
    Filed: November 30, 1998
    Date of Patent: May 9, 2006
    Assignee: Serono Genetics Institute, S.A.
    Inventors: Remy Griffais, Susan K. Hoiseth, Robert John Zagursky, Benjamin J. Metcalf, Joel A. Peek, Banumathi Sankaran, Leah Diane Fletcher
  • Patent number: 7030855
    Abstract: A wearable pixelated apparel video-displaying system is disclosed comprising at least one flexible lightweight pixelated material having a contiguous imaging surface comprised of a multitude of pixels capable of displaying typical video rate, video image content which is contiguous in appearance and which covers up to all of the surface. The apparatus is equipped to playback, control and display imagery according to the size and the shape of one or more pixelated material segments making up the video-displaying apparel. The apparatus has an input/output interface a digital media content playback device, a user interface means for a user to communicate with the apparatus and to control the playback of at least one source of video content. In one embodiment the pixelated-image displaying apparel is contiguously formed into a single garment. In a second embodiment a plurality of apparel segments are adjoined to one another by attachment, and are electronically coupled together.
    Type: Grant
    Filed: August 13, 2001
    Date of Patent: April 18, 2006
    Inventor: Darrell J. Metcalf
  • Patent number: 7004377
    Abstract: A food serving apparatus having a flat food-supporting member consisting of a material sized to prevent served food from contacting unsanitary surfaces, and having sufficient rigidity, to support one or more food items. The food-supporting member has at least one food-retaining portion integrally formed adjacent thereto which extends upward, or can be positioned upward by a user, relative to the food-supporting member, in a manner which increases rigidity of the member. The food-supporting member has at least one bendable cross-section tangent to at least one user-breakable joint of a food-retaining portion to allow separation of the separable joint(s). Breaking of the joint(s) allows a user to bend the food-supporting member downward and away from food supported to facilitate the eating experience. The apparatus accommodates a variety of shapes and optionally includes a fold-over tab to assist a user in securing food beneath the tab and above the food-supporting member.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: February 28, 2006
    Inventor: Darrell J. Metcalf
  • Publication number: 20050183207
    Abstract: This invention relates to new compositions and methods for cleaning textile substrates, especially carpet and upholstery fabrics. More particularly, this invention relates to liquid compositions that contain absorbent particles in a flowable fluid dispersion, which dries to a soil ladened powder, that can be removed by vacuuming, brushing, and/or laundering methods. The composition includes dispersion stabilizing additives such that the composition is presented as a stable dispersion or as a composition that may be easily redispersed prior to application.
    Type: Application
    Filed: February 20, 2004
    Publication date: August 25, 2005
    Inventors: Marie Chan, Steven Brown, Patrick Moore, J. Metcalf, Michael Valenti, Michael McDonald
  • Publication number: 20050183206
    Abstract: This invention relates to new compositions and methods for cleaning textile substrates, especially carpet and upholstery fabrics. More particularly, this invention relates to liquid compositions that contain absorbent particles in a flowable fluid dispersion, which dries to a soil ladened powder, that can be removed by vacuuming, brushing, and/or laundering methods. The composition includes dispersion stabilizing additives such that the composition is presented as a stable dispersion or as a composition that may be easily redispersed prior to application.
    Type: Application
    Filed: February 20, 2004
    Publication date: August 25, 2005
    Inventors: Steven Brown, Marie Chan, Michael Valenti, Michael McDonald, Shannon Stancil, J. Metcalf, Patrick Moore
  • Publication number: 20040192591
    Abstract: The invention relates to therapeutic modalities and pharmaceutical compositions for the treatment of Chlamydia-infection using cyclophilin polypeptides and its corresponding human cellular binding partner or partners as a target for intervention. The present invention relates to the use of exogenous or engrafted sources of cyclophilins, anti-cyclophilin antibodies, cyclophilin decoys, soluble forms of cyclophilin-binding partners and small molecules which are supplied extracellularly, and act presumably by interrupting the binding of cyclophilin A with its cellular binding partner(s) or receptor(s), as a treatment for Chlamydia-infection. The present invention further relates to screening assays for the identification of compounds that inhibit the interaction of cyclophilin and its Chlamydia binding partners.
    Type: Application
    Filed: November 24, 2003
    Publication date: September 30, 2004
    Inventors: Joseph L. Wooters, Benjamin J. Metcalf, Banumathi Sankaran
  • Publication number: 20040167068
    Abstract: The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.
    Type: Application
    Filed: September 2, 2003
    Publication date: August 26, 2004
    Inventors: Gary W. Zlotnick, Leah Diane Fletcher, John Erwin Farley, Liesel A. Bernfield, Robert J. Zagursky, Benjamin J. Metcalf
  • Publication number: 20040056770
    Abstract: A system for preventing the hijacking, or suicide-bombing, of aircraft, ocean-going vessels, or trains, having at least one onboard vehicle computer capable of operating the vehicle in an automated transportational mode along at least one path when any attempt to overtake or divert the vehicle is made or suspected, or threat of harm to any vehicle-personnel is made or suspected. The system has at least one signal receiver interfaced with, and having a communication link with, the computer(s), and the computer(s) is configured to be responsive to at least one secure signal when initiated by at least one user aboard the vehicle and sent from at least one signal transmitter to the signal receiver(s). The transmitter(s) has an easy-to-use user-interface which is operated by an engagement of at least one finger of user's hand to cause the signal to be sent to the receiver(s).
    Type: Application
    Filed: September 19, 2002
    Publication date: March 25, 2004
    Inventor: Darrell J. Metcalf
  • Publication number: 20040035863
    Abstract: A folds-as-you-eat multi-purpose food-serving apparatus (‘MPFSA’) that is supportable from one end by one hand during eating, and has optional exhibiting means for providing multi-minute close-proximity exposures promoting observer-discernible content and/or user-discernible content, and optionally providing recreational, or display, functionality. The MPFSA is comprised of one or more materials having a pliability which accommodates the bending and unbending of the apparatus a plurality of times in a manner that will not significantly alter the presentation of served food. The MPFSA is also comprised of material(s) having sufficient rigidity to support one or more items of food, having a food-supporting surface which is stiffened by at least one adjacent food-retaining portion which extends upward from an edge thereof, or can be so positioned by a user, to increase the rigidity of, and facilitate the retention of served food on, the apparatus.
    Type: Application
    Filed: August 20, 2002
    Publication date: February 26, 2004
    Inventors: Darrell J. Metcalf, Michael Goodrow
  • Publication number: 20040006218
    Abstract: The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia pneumoniae, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication process or in virulence, polypeptides encoded by such sequences, as well as vectors including the said sequences and cells or animals transformed with these vectors. The invention also relates to transcriptional gene products of the Chlamydia pneumoniae genome, such as, for example, antisense and ribozyme molecules, which can be used to control growth of the microorganism. The invention also relates to methods of detecting these nucleic acids or polypeptides and kits for diagnosing Chlamydia pneumoniae infection. The invention also relates to a method of selecting compounds capable of modulating bacterial infection and a method for the biosynthesis or biodegradation of molecules of interest using the said nucleotide sequences or the said polypeptides.
    Type: Application
    Filed: November 7, 2002
    Publication date: January 8, 2004
    Applicant: Genset S.A.
    Inventors: Remy Griffais, Susan K. Hoiseth, Robert John Zagursky, Benjamin J. Metcalf, Joel A. Peek, Banumathi Sankaran, Leah Diane Fletcher
  • Patent number: 6669346
    Abstract: A panoramic imaging and display system for the imaging and displaying of visual-media content, comprising a screen configured for the display of panoramic imagery, having an interior surface-perimeter and an exterior surface-perimeter, wherein each of said surface-perimeters are substantially contiguous in appearance and are sized and shaped to have a display area on which, substantially contiguous panoramic visual-media content and segmented visual-media content can be imaged. The system provides support and positioning of the display to at least one height relative to a viewing audience to provide circumnavigable viewing, and a multitude of vantage points from which to view at least one of the surface-perimeters of the panoramic display. Embodiments of the system can have an array of speakers positioned around a perimeter of the system's screen as a sound-system providing a panning of audible sound which can be synchronized with the movement of objects seen moving on the screen.
    Type: Grant
    Filed: May 12, 2001
    Date of Patent: December 30, 2003
    Inventor: Darrell J. Metcalf
  • Patent number: 6559294
    Abstract: The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia pneumoniae, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication process or in virulence, polypeptides encoded by such sequences, as well as vectors including the said sequences and cells or animals transformed with these vectors. The invention also relates to transcriptional gene products of the Chlamydia pneumoniae genome, such as, for example, antisense and ribozyme molecules, which can be used to control growth of the microorganism. The invention also relates to methods of detecting these nucleic acids or polypeptides and kits for diagnosing Chlamydia pneumoniae infection. The invention also relates to a method of selecting compounds capable of modulating bacterial infection and a method for the biosynthesis or biodegradation of molecules of interest using the said nucleotide sequences or the said polypeptides.
    Type: Grant
    Filed: November 23, 1998
    Date of Patent: May 6, 2003
    Assignee: Genset, S.A.
    Inventors: Remy Griffais, Susan K. Hoiseth, Robert John Zagursky, Benjamin J. Metcalf, Joel A. Peek, Banumathi Sankaran, Leah Diane Fletcher
  • Publication number: 20020167483
    Abstract: Visually-dynamic pixelated-image displaying apparel is disclosed comprising at least one flexible lightweight pixelated material having a contiguous imaging surface comprised of a multitude of pixels. The flexible pixelated material has electronic coupling means with at least one image-playback/image-control apparatus equipped to playback, control and display imagery according to the size and the shape of one or more pixelated material segment making up the displaying apparel. The image-playback/image-control apparatus is comprised of at least one control circuit, at least one intelligent controller, an electronic power source, at least one input/output interface means to receive and send digital media content, at least one digital media content playback means, a user interface means for a user to communicate with said apparatus and to control the playback of at least one source of digital media content, and intelligent controller software responsive to user input from said user interface means.
    Type: Application
    Filed: August 13, 2001
    Publication date: November 14, 2002
    Inventor: Darrell J. Metcalf
  • Publication number: 20020088168
    Abstract: This invention is a mixture of low-vapor-pressure hydrocarbon fuels and carbon dioxide mixed at normal pressures and temperatures in a ratio that facilitates the production of micro-droplets that enhance combustion in diesel and similar fuel burning engines resulting in a reduction of particulates ejected and a gain in efficiency. The presence of the gas in the fuel also decreases flammability in the atmosphere above the fuel surface.
    Type: Application
    Filed: January 8, 2002
    Publication date: July 11, 2002
    Inventors: Clyde L. Tichenor, Darrell J. Metcalf
  • Publication number: 20020023265
    Abstract: The present invention generally relates to a method and system for communicating signals between handheld wireless communications devices and large-screen projection systems, or large-screen display systems, or both, via one or more publicly-accessible communications link. The invention provides the means for such devices to serve as interactive controllers of screen-content which is projected, or otherwise displayed, on such screen systems.
    Type: Application
    Filed: August 7, 2001
    Publication date: February 21, 2002
    Inventor: Darrell J. Metcalf
  • Publication number: 20020007804
    Abstract: A fuel additive controlling and maintaining apparatus used to eliminate the loss of absorbed CO2 gas mixed into liquid hydrocarbon fuel and particularly diesel fuel. In addition to the gas-enriched fuel, a gastight bag is utilized for holding a stabilizing gas mixture of CO2 and air that is not absorbed in the fuel. This bag, which is located within a protective enclosure and is connected into the ullage of a fuel tank, via a conduit, has approximately the same volume as the fuel tank. A two product refueling means is provided so that gas-enriched fuel is delivered to the fuel tank and the CO2 gas is delivered to the gastight bag. During fuel usage, as the fuel tank ullage increases, the gas mixture from the gastight bag maintains the ullage in a substantially filled condition thus, allowing the fuel to remain gas-enriched.
    Type: Application
    Filed: July 18, 2001
    Publication date: January 24, 2002
    Inventors: Clyde LeRoy Tichenor, Irwin Ginsburgh, Darrell J. Metcalf
  • Publication number: 20010040671
    Abstract: A large-audience, positionable imaging and display system for the imaging and displaying of visual-media content, comprising a screen configured for the display of panoramic imagery having an interior surface-perimeter and an exterior surface-perimeter, wherein each of said surface-perimeters are substantially contiguous in appearance and are sized and shaped to have a display area on which, substantially contiguous panoramic visual-media content and segmented visual-media content can be imaged. The system has at least one support means for supporting the shape of a panoramic screen-display and a screen positioning means for positioning the display to at least one height relative to a viewing audience to provide circumnavigable viewing, and a multitude of vantagepoints from which to view at least one of the surface-perimeters of the panoramic display.
    Type: Application
    Filed: May 12, 2001
    Publication date: November 15, 2001
    Inventor: Darrell J. Metcalf
  • Patent number: 6298897
    Abstract: A system for reversibly rotating a shaft for operation of the control system in a covering for an architectural opening includes two relatively linearly moveable members at least one of which has a low friction component engaging a helical path on the other so that linear movement of the members causes relative rotation to drive the rotatable shaft of the control system.
    Type: Grant
    Filed: May 1, 2000
    Date of Patent: October 9, 2001
    Assignee: Hunter Douglas Inc.
    Inventors: Darrell J. Metcalf, Clyde L. Tichenor, Irwin Ginsburgh