Abstract: Systems and methods for filtration of expiratory gases are disclosed. In an example, the technology relates to a method for replacing expiratory filters of a ventilation system without breaking a breathing circuit. The method may include opening a first channel and closing a second channel such that expiratory gases flow through a first filter coupled to the first channel; closing the first channel and opening the second channel such that the expiratory gases flow through a second filter coupled to the second channel; and while the expiratory gases are flowing through the second channel, replacing filter media of the first filter while maintaining pressure in the breathing circuit.

Abstract: A drill system including a drill and a secondary computing device. The drill includes a housing, a controller, a wireless transceiver, a motor, and a chuck. The motor, the controller and the wireless transceiver are housed in the housing. The chuck is selectively driven by the motor. The secondary computing device includes a wireless transceiver which allows wireless communication between the drill and the secondary computing device. The secondary computing device further includes a user interface configured to allow an operator to change operating parameters of the drill. The operating parameters are configured to be automatically reset.

Abstract: Disclosed are systems and methods for mitigation of fraudulent transactions. In some embodiments, a server is communicatively coupled to a user device, and is configured to receive a proposed transaction from a merchant device communicatively coupled to the server, apply a dynamic classification algorithm to the proposed transaction to determine if the proposed transactions appears to be fraudulent, generate a user verification request when the proposed transaction appears to be fraudulent, transmit the user verification request to a user computing device communicatively coupled to the server, receive an approval or a refusal of the proposed transaction based on the user verification request, and process the proposed transaction based on the received approval or refusal of the proposed transaction.

Abstract: A dispersion contains: (a) a polyorganosiloxane with at least 90 mole % dimethyl D units and viscosity of one kPa*s or more dispersed as 0.5-20 micrometer particles; (b) a condensation product of: (i) a polysiloxane resin (Mw of 4,000-50,000) with composition: (R3SiO1/2)a(SiO4/2)b(ZO1/2)c where a is 0.30-0.60, b is 0.40-0.70, c is 0.05-0.20, a+b is one, R is selected from hydrogen, C1?30 alkyl groups and aryl groups, and Z is selected from H, and C18 alkyls; and (ii) a polyoxyalkylene polymer (Mn of 4,500-50,000) with composition: A—O—(C2H4O)e(C3H6O)p—A? where e/p is 1-9, A and A? are selected from hydrogen, alkyl, substituted alkyl, aryl, and substituted aryl groups and at least one of A and A? is H; (c) non-aqueous fluid carrier miscible with (a); and (d) monoterpene; the weight-ratio of (c) to (b) is 0.5-1; weight-ratio of (b) and (c) to (a) is 0.01-0.50; and the composition contains below one ppm aromatic solvent.

Abstract: The invention provides cereblon binders of Formulas: or pharmaceutically acceptable salts thereof, for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway along with their use in therapeutic applications to treat medical disorders including, but not limited to cancer.

Abstract: This invention provides Degronimers that have E3 Ubiquitin Ligase targeting moieties (Degrons) that can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation. The invention also provides Degrons that can be used to treat disorders mediated by cereblon or an Ikaros family protein, and methods of use and compositions thereof as well as methods for their preparation.

Abstract: Embodiments of the invention are directed to compositions containing cannabinoid, cannabidiol, cannabidiol isomer, or cannabidiol analog and combinations thereof for treating dermatological disease, and methods for treating dermatological diseases by administering compositions containing cannabinoid, cannabidiol, or cannabidiol analog to the skin of a patient in need of treatment.

Abstract: Embodiments of the invention are directed to compositions containing cannabinoid, cannabidiol, cannabidiol isomer, or cannabidiol analog and combinations thereof for treating dermatological disease, and methods for treating dermatological diseases by administering compositions containing cannabinoid, cannabidiol, or cannabidiol analog to the skin of a patient in need of treatment.

Abstract: A wall panel system including a first wall panel, the first panel including at least a first panel hook portion. The system also including a second wall panel having a different configuration than the first wall panel. The second panel includes at least a second panel hook portion and a third panel hook portion opposing the second panel hook portion. The first wall panel is configured to engage with the second wall panel to create a wall panel assembly.

Abstract: Methods for forming single crystal silicon ingots with improved resistivity control are disclosed. The methods involve growth of a sample rod. The sample rod may have a diameter less than the diameter of the product ingot. The sample rod is cropped to form a center slab. The resistivity of the center slab may be measured directly such as by a four-point probe. The sample rod or optionally the center slab may be annealed in a thermal donor kill cycle prior to measuring the resistivity, and the annealed rod or slab is irradiated with light in order to enhance the relaxation rate and enable more rapid resistivity measurement.

Abstract: A dispersion contains: (a) a polyorganosiloxane with at least 90 mole % dimethyl D units and viscosity of one kPa*s or more dispersed as 0.5-20 micrometer particles; (b) a condensation product of: (i) a polysiloxane resin (Mw of 4,000-50,000) with composition: (R3SiO1/2)a(SiO4/2)b(ZO1/2)c where a is 0.30-0.60, b is 0.40-0.70, c is 0.05-0.20, a+b is one, R is selected from hydrogen, C1-30 alkyl groups and aryl groups, and Z is selected from H, and C1-8 alkyls; and (ii) a polyoxyalkylene polymer (Mn of 4,500-50,000) with composition: A-O—(C2H4O)e(C3H6O)p-A? where e/p is 1-9, A and A? are selected from hydrogen, alkyl, substituted alkyl, aryl, and substituted aryl groups and at least one of A and A? is H; (c) non-aqueous fluid carrier miscible with (a); and (d) monoterpene; the weight-ratio of (c) to (b) is 0.5-10; weight-ratio of (b) and (c) to (a) is 0.01-0.50; and the composition contains below one ppm aromatic solvent.

Abstract: A drill system including a drill and a secondary computing device. The drill includes a housing, a controller, a wireless transceiver, a motor, and a chuck. The motor, the controller and the wireless transceiver are housed in the housing. The chuck is selectively driven by the motor. The secondary computing device includes a wireless transceiver which allows wireless communication between the drill and the secondary computing device. The secondary computing device further includes a user interface configured to allow an operator to change operating parameters of the drill. The operating parameters are configured to be automatically reset.

Abstract: A battery pack power transfer adaptor and a battery pack system that includes a battery pack adaptor. The adaptor enables a battery pack to provide high level power transfers to a variety of devices and to receive high level power transfers from a variety of power sources. The adaptor includes a battery pack interface to enable the adaptor to mechanically and electrically connect to the battery pack. The adaptor is able to transfer power at a variety of levels dependent upon the device to which it is attached.

Abstract: Disclosed herein are system, method, and computer program product embodiments for authenticating a mobile user via an authentication method determined based on a token level associated with the action being completed. An authentication token is created corresponding to the token level and the authentication token is sent to the mobile device. This authentication token may be used to authenticate subsequent actions and engage various services to complete the actions using application programming interfaces. The authentication token stored on the mobile device obviates the need for a user to authenticate multiple times to complete actions requiring a similar token level. The system may authenticate the identity of the mobile user using various authentication methods.

Abstract: A method for drilling a subterranean wellbore includes rotating a drill string in the subterranean wellbore. The drill string includes a drill collar, a drill bit, and survey sensors (e.g., a triaxial accelerometer set and a triaxial magnetometer set) deployed therein. The triaxial accelerometer set and the triaxial magnetometer set make corresponding accelerometer and magnetometer measurements while drilling (rotating). These measurements are synchronized to obtain synchronized accelerometer and magnetometer measurements and then further processed to compute at least an inclination and an azimuth of the subterranean wellbore while drilling. The method may further optionally include changing a direction of drilling the subterranean wellbore in response to the computed inclination and azimuth.

Abstract: Systems and methods for fluid delivery into a ventilation system are disclosed. In an example, the technology relates to a fluid delivery system for delivery of aerosolized liquid. The fluid delivery system includes an injection tip having a set of orifices configured to aerosolize a liquid having certain properties. The injection tip may be couplable with components of a breathing circuit. For example, the injection tip may be couplable with components at or below a wye component (e.g., at a wye component or between the wye component and a patient), such as at the wye component or at an endotracheal tube multi-port connector. Alternatively, the injection tip may be integrated into a breathing circuit, such as at an endotracheal tube connector or at an endotracheal tube.

Abstract: A humidification system including a conduit for carrying breathing gases, a pump to pressurize a liquid for injection into breathing gases, a liquid-injection nozzle protruding at least partially into the conduit and configured to inject liquid, pressurized by the pump, into the conduit; and a heated surface protruding into the conduit and positioned to vaporize the liquid injected by the nozzle, wherein the heated surface crosses a flow path of the breathing gases flowing through the conduit.

Abstract: New treatments for Ikaros and/or Aiolos mediated disorders are provided that comprise administering an effective amount of a cereblon binder that degrades Ikaros or Aiolos by the ubiquitin proteasome pathway.

Abstract: Systems and methods for collecting breathing gas properties via a medical ventilatory filter and wirelessly transmitting the data to another device. For example, the filter includes a first housing enclosing filtration media for filtering breathing gases flowing through the filter, the first housing defining a first port and a second port exposed to the breathing gases; and a sensor assembly. The sensor assembly includes a first sensor coupled to the first port, the first sensor configured to capture measurement data for a first gas property of breathing gases flowing through the filter; a second sensor coupled to the second port, the second sensor configured to capture measurement data for a first gas property of the breathing gases flowing through the filter; and a second housing. The second housing includes a processor and communication circuitry operative to wirelessly communicate the sensor data to a computing device located remotely from the filter.

Abstract: Disclosed herein are system, method, and computer program product embodiments for creating a personalized barcode for an account holder at an Automated Teller Machine (ATM). An embodiment operates by storing account holder unique data and a first rule for generating a personalized barcode unique to the account holder based on the account holder unique data. After receiving a request for completion of a transaction from the first account holder, placing the account holder unique data and the first rule in a pairing service. Thereafter, the ATM is configured to retrieve the account holder unique data and the first rule from the pairing service, generate the first personalized barcode based on the first rule and the account holder unique data, and present the first personalized barcode to the first account holder.