Abstract: A vehicle system including a pre-trip inspection algorithm includes a service brake controller for controlling service brakes at a plurality of wheel ends of a vehicle and for monitoring a change of state of the vehicle, a parking brake controller for controlling parking brakes at a plurality of wheel ends and in communication with the service brake controller; and a driver interface unit in communication with the service brake controller for receiving a driver request for an automated pre-trip inspection of a vehicle. In response to the driver request for an automated pre-trip inspection, the service brake controller automatically applies the service brakes and in response to a change of state of the vehicle, the parking brake controller applies the parking brakes automatically.

Abstract: An apparatus includes a thermal actuator switch configured to control a transfer of thermal energy through the thermal actuator switch. The thermal actuator switch includes first and second plates and a piston movable laterally between the first and second plates. The thermal actuator switch also includes a phase change material configured to (i) expand to move a surface of the piston into a first position and (ii) contract to allow the surface of the piston to move into a second position. The surface of the piston thermally contacts the first plate and increases thermal energy transfer between the first and second plates when in one of the first and second positions. The surface of the piston is spaced apart from the first plate and decreases thermal energy transfer between the first and second plates when in another of the first and second positions.

Abstract: A lubricant supply system is for a compressor that compresses a first working fluid in a heat transfer circuit. The lubricant supply system includes a lubricant tank, a lubricant pathway for supplying lubricant from the lubricant tank to one or more bearings of the compressor, and a lubricant refrigeration system with a lubricant heater and a lubricant cooler. The lubricant heater configured to heat the lubricant discharged from the one or more bearings and the lubricant cooler configured to cool the lubricant flowing through the lubricant pathway. A method of lubricating a compressor includes heating the lubricant, directing the lubricant from a lubricant tank through a lubricant pathway to one or more bearings of the compressor, and cooling the lubricant passing through the lubricant pathway.

Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human CD200R1 receptor protein (hu-CD200R1) and are capable of decreasing, inhibiting, and/or fully-blocking immune regulatory effects mediated by hu-CD200R1. The present disclosure also provides methods of using the antibodies (and compositions thereof) to treat diseases and conditions responsive to decreasing, inhibiting and/or blocking immune regulatory function or activity mediated by CD200 binding to CD200R1.

Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human CD200R1 receptor protein (hu-CD200R1) and are capable of decreasing, inhibiting, and/or fully-blocking immune regulatory effects mediated by hu-CD200R1. The present disclosure also provides methods of using the antibodies (and compositions thereof) to treat diseases and conditions responsive to decreasing, inhibiting and/or blocking immune regulatory function or activity mediated by CD200 binding to CD200R1.

Abstract: A heat spreading element is provided. The heat spreading element includes compressible pyrolytic graphite sheets and rigid pyrolytic graphite sheets interleaved with the compressible pyrolytic graphite sheets.

Abstract: A lubricant supply system is for a compressor that compresses a first working fluid in a heat transfer circuit. The lubricant supply system includes a lubricant tank, a lubricant pathway for supplying lubricant from the lubricant tank to one or more bearings of the compressor, and a lubricant refrigeration system with a lubricant heater and a lubricant cooler. The lubricant heater configured to heat the lubricant discharged from the one or more bearings and the lubricant cooler configured to cool the lubricant flowing through the lubricant pathway. A method of lubricating a compressor includes heating the lubricant, directing the lubricant from a lubricant tank through a lubricant pathway to one or more bearings of the compressor, and cooling the lubricant passing through the lubricant pathway.

Abstract: An electronic actuator assembly operates an in-line valve. A valve seat of the in-line valve is surrounded by a plate. The plate can include one or more openings configured to allow fluid to pass through the plate. A perimeter of the plate outside of the openings can be configured to have ends of pipes joined on either side of the plate. The in-line valve can be operated by an electronic actuator. The electronic actuator can be powered by a supply line that enters the assembly through the plate. The electronic actuator assembly can be incorporated in to a fluid circuit to serve as an expander. The electronic actuator can be located in a housing to direct flow around the electronic actuator. The electronic actuator can be installed in place of an orifice plate of an existing fluid circuit of a heating, ventilation, air conditioning, or refrigeration (HVACR) system.

Abstract: The disclosure relates to compounds of formula I which are useful as kinase modulators including RIPK 1 modulation. The disclosure also provides methods of making and using the compounds for example in treatments related to necrosis or inflammation as well as other indications.

Abstract: An apparatus includes multiple thermal actuator switches configured to control a transfer of thermal energy. The thermal actuator switches are arranged in a stacked configuration. Each switch includes first and second plates and a piston movable between the plates. Each switch also includes a phase change material configured to (i) expand to move a surface of the piston into a first position and (ii) contract to allow the surface of the piston to move into a second position. The surface of the piston thermally contacts the first plate and increases thermal energy transfer between the plates when in one of the first and second positions. The surface of the piston is spaced apart from the first plate and decreases thermal energy transfer between the plates when in another of the first and second positions. Different ones of the switches include different phase change materials that expand or contract at different temperatures.

Abstract: Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFN?, by acting on Tyk-2 to cause signal transduction inhibition.

Abstract: Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, (I) are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: Compounds having formula (I)-(IX), and enantiomers, and diastereomers, stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, (I) are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: An insulating tile may be attached to an interior or exterior surface adjacent to a chilled compartment of an aircraft galley structure to increase the overall thermal resistance of the galley structure (as well as the capacity of the galley air/liquid chiller system). The insulating tile includes an outer barrier encapsulating a thermally resistant core material within a vacuum, both the outer barrier and the core material resistant to flame propagation and thus suitable for commercial aircraft use. The insulating tile may further include getters within the core material to maintain the vacuum (and thus the thermal resistance of the tile) by absorbing moisture. Scannable passive pressure and/or moisture sensors may be placed within the core material for reporting at a glance the state of the vacuum, so that a particular tile may be serviced or replaced if necessary.

Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human CD200R1 receptor protein (hu-CD200R1) and are capable of decreasing, inhibiting, and/or fully-blocking immune regulatory effects mediated by hu-CD200R1. The present disclosure also provides methods of using the antibodies (and compositions thereof) to treat diseases and conditions responsive to decreasing, inhibiting and/or blocking immune regulatory function or activity mediated by CD200 binding to CD200R1.

Abstract: Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: A refrigerant circuit is disclosed. The refrigerant circuit includes a compressor, a condenser, a first expansion device, an economizer, a second expansion device, and an evaporator fluidly connected. A working fluid flows through the refrigerant circuit. A bypass segment is fluidly connected to the refrigerant circuit. A portion of the working fluid is provided from the refrigerant circuit to the bypass segment from a location in the refrigerant circuit disposed between the condenser and the evaporator with respect to flow of the working fluid. The portion of the working fluid flows through the bypass segment in a flow enabled state and is provided to a location in the refrigerant circuit disposed between the economizer and the evaporator with respect to flow of the working fluid. A vortical flow is induced at the location in the refrigerant circuit disposed between the economizer and the evaporator.

Abstract: Disclosed herein are various systems, methods, and apparatuses for providing a system independent Configuration Management Database identification system. In an implementation, a dynamic identification system correlates records of an originating system with records of an Authoritative Configuration Management Database (CMDB) including a set of one or more identifying rules that define a minimum amount of information in order to generate an identifying signature that serves as a common reference between a record of the originating system with a matching Configuration Item (CI) record of the ACMDB, receiving, from the originating system, information to generate an identifying signature, determining that the generated first identifying signature matches a stored identifying signature, and correlating the first record of the originating system corresponding with the generated first identifying signature with the one of the CI records of the ACMDB corresponding with the matching one of the identifying signatures.