Patents by Inventor J. Pitts

J. Pitts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazo-fused oxazolo [4,5-]pyridine and imidazo-fused thiazolo[4,5-]pyridine based tricyclic compounds and pharmaceutical compositions comprising same
    Patent number: 7456194
    Abstract: The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I), wherein R1, R2, R3, and R6 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: November 25, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Alaric Dyckman, William J. Pitts, Makonen Belema, Patrice Gill, James Kempson, Yuping Qiu, Claude Quesnelle, Steven H. Spergel, F. Christopher Zusi
  • Gas trap distributor for an evaporator
    Patent number: 7421855
    Abstract: A shell-and-tube evaporator of a refrigerant system includes a refrigerant inlet distributor that traps a pocket of gaseous refrigerant to displace liquid refrigerant underneath the evaporator's tube bundle, thereby reducing the total charge of refrigerant in the evaporator. In some embodiments, the distributor comprises four sections interconnected by a central refrigerant feed line, which properly apportions the refrigerant to the four sections.
    Type: Grant
    Filed: January 4, 2007
    Date of Patent: September 9, 2008
    Assignee: Trane International Inc.
    Inventors: H. Kenneth Ring, Kenneth J. Schultz, Steven J. Pitts, Ronald M. Cosby, II, Brian T. Sullivan
  • Gas trap distributor for an evaporator
    Publication number: 20080163637
    Abstract: A shell-and-tube evaporator of a refrigerant system includes a refrigerant inlet distributor that traps a pocket of gaseous refrigerant to displace liquid refrigerant underneath the evaporator's tube bundle, thereby reducing the total charge of refrigerant in the evaporator. In some embodiments, the distributor comprises four sections interconnected by a central refrigerant feed line, which properly apportions the refrigerant to the four sections.
    Type: Application
    Filed: January 4, 2007
    Publication date: July 10, 2008
    Inventors: H. Kenneth Ring, Kenneth J. Schultz, Steven J. Pitts, Ronald M. Cosby, Brian T. Sullivan
  • Fused heterocyclic compounds and use thereof
    Patent number: 7384937
    Abstract: Fused heterocylic compounds of the following Formula wherein R1, R2, R5, Z, J1 and J2 are described herein, and analogs thereof are provided which are useful in treating leukocyte activation-associated disorders.
    Type: Grant
    Filed: November 6, 2003
    Date of Patent: June 10, 2008
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Joseph Barbosa, William J. Pitts, Junqing Guo
  • Pyrazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same
    Patent number: 7329668
    Abstract: The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I), wherein R1, R2, R3, R4, R5 and R6 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.
    Type: Grant
    Filed: February 24, 2004
    Date of Patent: February 12, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yuping Qiu, Makonen Belema, Xuejie Yang, Fred Christopher Zusi, William J. Pitts
  • Barbituric acid derivatives as inhibitors of TNF-? converting enzyme (TACE) and/or matrix metalloproteinases
    Patent number: 7294624
    Abstract: The present application describes novel barbituric acid derivatives of formula I: or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, B, L, R1, R2, R3, R4, R5, n, W, U, X, Y, Z, Ua, Xa, Ya, and Za are defined in the present specification, which are useful as TNF-? converting enzyme (TACE) and matrix metalloproteinases (MMP) inhibitors.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: November 13, 2007
    Assignee: Bristol Myers Squibb Company
    Inventors: Jingwu Duan, Bin Jiang, Lihua Chen, Zhonghui Lu, Joseph Barbosa, William J. Pitts
  • Method for Catalytic Surface Protection
    Publication number: 20070231466
    Abstract: A method for protecting catalytic metal-based sensor for sensing the presence of hydrogen in an environment comprising, depositing a protective layer on said sensor, said protective layer being permeable to hydrogen.
    Type: Application
    Filed: May 23, 2007
    Publication date: October 4, 2007
    Applicant: MIDWEST RESEARCH INSTITUTE
    Inventors: Ping Liu, J. Pitts, Se-Hee Lee, C. Tracy
  • Photo-oxidation catalysts
    Publication number: 20070042906
    Abstract: Photo-oxidation catalysts and methods for cleaning a metal-based catalyst are disclosed. An exemplary catalyst system implementing a photo-oxidation catalyst may comprise a metal-based catalyst, and a photo-oxidation catalyst for cleaning the metal-based catalyst in the presence of light. The exposure to light enables the photo-oxidation catalyst to substantially oxidize absorbed contaminants and reduce accumulation of the contaminants on the metal-based catalyst. Applications are also disclosed.
    Type: Application
    Filed: August 19, 2005
    Publication date: February 22, 2007
    Inventors: J. Pitts, Ping Liu, R. Smith
  • HYDROGEN PERMEABLE PROTECTIVE COATING FOR A CATALYTIC SURFACE
    Publication number: 20070039372
    Abstract: A protective coating for a surface comprising a layer permeable to hydrogen, said coating being deposited on a catalyst layer; wherein the catalytic activity of the catalyst layer is preserved.
    Type: Application
    Filed: August 19, 2005
    Publication date: February 22, 2007
    Applicant: MIDWEST RESEARCH INSTITUTE
    Inventors: Ping Liu, C. Tracy, J. Pitts, Se-Hee Lee
  • Imidazo-fused oxazolo[4,5-?]pyridine and imidazo-fused thiazolo[4,5-?]pyridine based tricyclic compounds and pharmaceutical compositions comprising same
    Patent number: 7176214
    Abstract: The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I), wherein R1, R2, R3, R4, R5 and R6 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: February 13, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: William J. Pitts, Makonen Belema, Patrice Gill, James Kempson, Yuping Qiu, Claude A. Quesnelle, Steven H. Spergel, Fred Christopher Zusi
  • Acyl guanidine compounds and use thereof
    Patent number: 7109224
    Abstract: Acyl guanidine compounds of the following Formula wherein R1, R2, R3, R4 and L are described herein, and pharmaceutical compositions thereof, are useful in treating leukocyte activation-associated disorders.
    Type: Grant
    Filed: November 6, 2003
    Date of Patent: September 19, 2006
    Assignee: Bristol-Myers Squibb Co.
    Inventors: James Kempson, William J. Pitts
  • Fused heterocyclic compounds and use thereof
    Patent number: 7105667
    Abstract: Fused heterocylic compounds of the following Formula wherein R1, R2, R5, Z, J1 and J2 are described herein which are useful in treating leukocyte activation-associated disorders.
    Type: Grant
    Filed: November 6, 2002
    Date of Patent: September 12, 2006
    Assignee: Bristol-Myers Squibb Co.
    Inventors: William J. Pitts, Joseph Barbosa, Junqing Guo
  • Quinazoline and pyrido[2,3-d]pyrimidine inhibitors of phosphodiesterase (PDE) 7
    Patent number: 7022849
    Abstract: Quinazoline and pyrido[2,3-d]pyrimidine phosphodiesterase 7 (PDE 7) inhibitors of the following formula wherein R1, R2, L, Y1, Y2, Y3 and Z are as described herein, are provided which are useful in treating T-cell mediated diseases.
    Type: Grant
    Filed: June 17, 2002
    Date of Patent: April 4, 2006
    Assignee: Bristol-Myers Squibb Co.
    Inventors: William J. Pitts, Joseph Barbosa
  • Heterocycles that are inhibitors of IMPDH enzyme
    Patent number: 6919335
    Abstract: Compounds of the formula wherein X1 is C(O), —S(O)—, or —S(O)2—; X2 is CR3 or N; X3 is —NH—, —O—, or —S—; X4 is CR4 or N; X5 is CR5 or N; and X6 is CR6 or N are useful as inhibitors of IMPDH enzyme. Thus, these compounds can be used as therapeutic agents for IMPDH-associated disorders.
    Type: Grant
    Filed: April 23, 2001
    Date of Patent: July 19, 2005
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Edwin J. Iwanowicz, Scott H. Watterson, T. G. Murali Dhar, William J. Pitts, Henry H. Gu
  • Apparatus and method for measuring the mass of vegetation or fruit supported on a trellis
    Patent number: 6854337
    Abstract: The present disclosure concerns apparatus and methods useful in estimating crop yields of plants that are supported on a trellis. According to one aspect, a method for measuring the mass of trellised plant structures includes measuring the tension of a support wire of the trellis structure on which the plant structures are supported, such as with a load cell placed in-line with the support wire. The tension of the support wire is converted into the mass of new plant growth supported on the support wire, using, for example, an empirically derived algorithm specific to the trellis structure.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: February 15, 2005
    Assignees: The United States of America as represented by the Secretary of the Agriculture, Washington State University Research Foundation
    Inventors: Julie M. Tarara, John C. Ferguson, Francis J. Pierce, Marvin J. Pitts, Gary M. Hyde, Robert L. Wample, Andre L. Baritelle
  • Purine inhibitors of phosphodiesterase (PDE) 7
    Patent number: 6838559
    Abstract: Purine phosphodiesterase 7 (PDE 7) inhibitors of the following formulas wherein R1, Z, Y and J are described herein, and analogs thereof are provided which are useful in treated T-cell mediated diseases. R2 is defined by the following (a) heteroaryl, or heterocyclo, either of which may be optionally substituted with one to three groups T1, T2, T3; (b) aryl substituted with one to three groups T1, T2, T3 provided that at least one of T1, T2, T3 is other than H; or (c) aryl fused to a heteroaryl or heterocyclo ring wherein the combined ring system may be optionally substituted with one to three groups T1, T2, T3.
    Type: Grant
    Filed: June 17, 2002
    Date of Patent: January 4, 2005
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Wayne Vaccaro, Jacques Y. Roberge, Katerina Leftheris, William J. Pitts, Joseph Barbosa
  • Pyrazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same
    Publication number: 20040204432
    Abstract: The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I), 1
    Type: Application
    Filed: February 24, 2004
    Publication date: October 14, 2004
    Inventors: Yuping Qiu, Makonen Belema, Xuejie Yang, Fred Christopher Zusi, William J. Pitts
  • Fused heterocyclic compounds and use thereof
    Publication number: 20040142945
    Abstract: Fused heterocylic compounds of the following Formula 1
    Type: Application
    Filed: November 6, 2003
    Publication date: July 22, 2004
    Inventors: Joseph Barbosa, William J. Pitts, Junqing Guo
  • Acyl guanidine compounds and use thereof
    Publication number: 20040132750
    Abstract: Acyl guanidine compounds of the following Formula 1
    Type: Application
    Filed: November 6, 2003
    Publication date: July 8, 2004
    Inventors: James Kempson, William J. Pitts
  • Transmission shifter
    Patent number: D517462
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: March 21, 2006
    Assignee: DaimlerChrysler Corporation
    Inventors: Micheal R Castiglione, Robert J. Pitt, Kevin R Verduyn, Freeman J Thomas, Trevor M Creed, Thomas G Tremont