Patents by Inventor J. Simons
J. Simons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12384852Abstract: This invention is directed to treatment of a subject having or suspected of having a cancer comprising administering to the subject a monoclonal antibody and NK-92 expressing Fc receptor.Type: GrantFiled: November 18, 2021Date of Patent: August 12, 2025Assignees: Institute for Cancer Research, ImmunityBio, Inc.Inventors: Tien Lee, Hans G. Klingemann, Barry J. Simon, Laurent Boissel, Kerry Campbell
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Patent number: 12377260Abstract: Vagal nerve stimulation devices and methods are provided herein. A device comprises one or more electrodes having a contact surface for contacting an outer skin surface of a patient and an energy source coupled to the electrodes. The energy source generates one or more electrical impulses and transmits the electrical impulses to the electrodes and transcutaneously through the outer skin surface of the patient at or near a vagus nerve. The one or more electrical pulses comprise bursts of 2 to 20 pulses within each burst with each burst having a frequency of about 5 Hz to about 100 Hz.Type: GrantFiled: July 22, 2024Date of Patent: August 5, 2025Assignee: Electrocord, Inc.Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
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Patent number: 12364364Abstract: A solid pellet fueled apparatus having a duel auger system and multi/high speed auger motor is disclosed. The duel auger may include first and second auger blades mounted on a single auger shaft having blade pitches configured to convey solid fuel in opposite directions towards a central burn pot. Each auger blade may service a separate solid fuel compartment provided in a single hopper. The auger motor may have a high-speed setting that may be selected for solid fuel clean out.Type: GrantFiled: March 15, 2022Date of Patent: July 22, 2025Assignee: WH PRODUCTS, LLC.Inventors: Paul J. Simon, Michael R. Giebel, Xianjia Fan
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Patent number: 12345703Abstract: The invention relates to methods and reagents for analyzing samples for the presence of JC virus antibodies.Type: GrantFiled: March 25, 2022Date of Patent: July 1, 2025Assignee: Biogen MA Inc.Inventors: Leonid Gorelik, Kenneth J. Simon, Meena Subramanyam, Mia Marie Rushe
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Patent number: 12329964Abstract: Methods are disclosed for electrical stimulation of nerves to treat one or more symptoms in a user. The methods comprise transcutaneously transmitting electrical impulses to the nerve according to a treatment paradigm. The treatment paradigm may include generating and transmitting the electrical impulse as a single dose from about 30 seconds to about 5 minutes. The treatment paradigm may comprise a treatment session of 2 to 4 times within an hour time period and/or as a single dose from 2 to 5 times during a day.Type: GrantFiled: August 1, 2023Date of Patent: June 17, 2025Assignee: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico
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Publication number: 20250170181Abstract: Provided herein are pharmaceutical compositions comprising tumoricidal and/or antimicrobial components isolated from the supernatant of NK-92 cell medium and methods of using the compositions for killing cancer cells.Type: ApplicationFiled: January 17, 2025Publication date: May 29, 2025Applicant: ImmunityBio, Inc.Inventors: Hans G. Klingemann, Barry J. Simon
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Publication number: 20250164115Abstract: A cooking grill includes a multi-compartment solid fuel hopper, a burn pot, and a tapered auger blade disposed between the solid fuel hopper and the burn pot. The grill further includes a transparent window for viewing solid fuel in the auger system, a smoke tap connected to a cooking chamber of the grill, and a steam drawer.Type: ApplicationFiled: November 18, 2024Publication date: May 22, 2025Applicant: WH Products, LLCInventors: Michael R. Giebel, Paul J. Simon, Alexandra Devi Upadhyaya
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Publication number: 20250152939Abstract: Systems, devices and methods are provided for stimulating one or more nerves within a user. A system comprises stimulator having an electrode configured for contacting the outer skin surface at a target location and an energy source coupled to the stimulator, The energy source is configured to generate at least one electrical impulse and to transmit the electrical impulse transcutaneously from the electrode through the outer skin surface of the user to a selected nerve in the user. In certain aspects, the systems and methods are particularly useful for non-medical purposes, such as reducing stress and anxiety, enhancing relaxation, improving sleep, energy, concentration and mood, increasing mental or physical performance, promoting mental health, recovery and wellness, generally improving the health and wellbeing of a user and/or for temporarily or permanently improving intelligence, learning capacity, memory retention, recall, mood, alertness and/or sleep efficiency in human beings.Type: ApplicationFiled: November 2, 2024Publication date: May 15, 2025Inventors: Bruce J. Simon, Joseph P. Errico, Peter Staats, Jonathan Gardiner, Jeckin Shah, Michael Romaniw
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Publication number: 20250151953Abstract: Embodiments of a cooking station having a main body and a griddle with a hood pivotably coupled to the griddle are provided. The hood is pivotably moveable between closed and fully open positions. Further, the hood is removable from the griddle to be positioned, for example, along a rear side of the main body in a low-profile position such that the hood may be suspended from the griddle with a hook structure.Type: ApplicationFiled: November 26, 2024Publication date: May 15, 2025Inventors: Tyler J. Fullmer, Mauricio J. Escobedo, Michael R. Giebel, Paul J. Simon
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Publication number: 20250141611Abstract: Techniques are disclosed relating to generating and receiving radio frames with multiple portions that each include multiple service data streams, where each service data stream may have a different physical layer encoding, and where each service data stream includes multiple orthogonal frequency division multiplexing (OFDM) symbols. Each of the multiple portions also includes control data indicating one or more service data streams that the apparatus is permitted to access. One or more of the service data streams are selected based on the control data, and the selected one or more service data streams are decoded to determine data represented by the OFDM symbols in the selected one or more service data streams.Type: ApplicationFiled: December 9, 2024Publication date: May 1, 2025Applicant: ONE MEDIA, LLCInventors: Michael J. SIMON, Kevin A. SHELBY, Mark EARNSHAW
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Publication number: 20250134444Abstract: Systems and methods for non-invasive nerve stimulation are provided. A method for treating a patient with a medical condition comprises contacting an outer skin surface of a patient with a contact surface of a stimulator, generating an electrical impulse, and transmitting the electrical impulse from the stimulator transcutaneously through the outer skin surface to a nerve within the patient. The method further includes detecting a physiological parameter of the patient during the transmitting and modifying one or more parameters of the electrical impulse applied to the nerve based on the physiological parameter.Type: ApplicationFiled: January 2, 2025Publication date: May 1, 2025Applicant: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico
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Publication number: 20250141580Abstract: A method for operating a transmitting device to communicate with a receiving device is described herein. The method includes the step of the transmitting device selecting a root index value from a set of root index values. The method further includes the step of the transmitting device generating a frequency domain Constant Amplitude Zero Auto-Correlation sequence based on the selected root index value. The method further includes the step of the transmitting device modulating the Constant Amplitude Zero Auto-Correlation sequence by a pseudo-noise sequence. The method further includes the step of the transmitting device generating an Orthogonal Frequency Division Multiplexing symbol, wherein the frequency domain Constant Amplitude Zero Auto-Correlation sequence modulated by the pseudo-noise sequence defines subcarrier values for the Orthogonal Frequency Division Multiplexing symbol.Type: ApplicationFiled: November 25, 2024Publication date: May 1, 2025Applicant: ONE MEDIA, LLCInventors: Kevin A. SHELBY, Michael J. SIMON, Mark EARNSHAW, Zahir Jaffer RAZA
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Publication number: 20250117545Abstract: Devices and methods are described to produce therapeutic effects in a patient by utilizing an energy source that transmits energy non-invasively to nervous tissue. A device for modulating a nerve within a body of a patient comprises a housing comprising a power supply and a signal generator for generating an electrical impulse. The electrical impulse comprises bursts of 2 to 20 pulses, wherein each of the bursts has a frequency of 15 to 50 Hz. The device further comprises first and second electrodes coupled to the housing and having a contact surface configured for contacting an outer skin surface of a neck of a user. The energy source is configured to transmit the electrical impulse from the first and second electrodes through the outer skin surface of the user to a vagus nerve.Type: ApplicationFiled: December 17, 2024Publication date: April 10, 2025Applicant: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
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Publication number: 20250082924Abstract: Devices and methods for the non-invasive stimulation of nerves, such as the vagus nerve, include a housing and an electrode coupled to the housing. The electrode is configured to be positioned adjacent to, or in contact with, an outer skin surface of a patient. A source of energy is coupled to the housing and operably coupled to the electrode. The source of energy emits an electrical impulse to the electrode such that the electrical impulse passes through the outer skin surface of the patient to a nerve at a target region in the patient sufficient to modulate the nerve.Type: ApplicationFiled: November 26, 2024Publication date: March 13, 2025Applicant: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
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Publication number: 20250081980Abstract: This disclosure relates to methods, systems and compositions for food coloring. Embodiments disclosed herein may include methods and systems for combining tea leaves and water to form a feed slurry; processing a feed slurry to at least partially remove a tea essence from the feed slurry, thereby obtaining a tea extract with a predetermined amount of one or more of an aroma or a flavor; and adjusting a color of the tea extract, thereby obtaining a coloring agent with a predetermined color-related feature, wherein the coloring agent is added in a predetermined amount to a food product to adjust a color of the food product. Embodiments may also including coloring compositions, which may include a dry tea extract, wherein an essence has been removed from the dry tea extract to a predetermined amount, and a color of the dry tea extract has been adjusted to have a predetermined color-related feature.Type: ApplicationFiled: September 12, 2024Publication date: March 13, 2025Applicant: Florida Food Products, LLCInventors: Kenneth J. Simone, D. Scott Lineback, Rajesh R. Jetti, Danish Yazdani, Gregg Lance Lehmberg
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Patent number: 12239256Abstract: A battery-operated wireless control system for outdoor cooking and heating appliances is disclosed. The system may include an electronic controller paired to a wireless temperature probe and a wireless monitor device capable of storing and recharging the wireless temperature probe. The electronic controller may control the operation of a fuel supply assembly, a fan assembly, and a spark generating assembly included in the appliance.Type: GrantFiled: April 7, 2022Date of Patent: March 4, 2025Assignee: WH PRODUCTS, LLCInventors: Paul J. Simon, Michael R. Giebel
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Patent number: 12234991Abstract: A solid pellet fueled apparatus having a duel auger system and multi/high speed auger motor is disclosed. The duel auger may include first and second auger blades mounted on a single auger shaft having blade pitches configured to convey solid fuel in opposite directions towards a central burn pot. Each auger blade may service a separate solid fuel compartment provided in a single hopper. The auger motor may have a high-speed setting that may be selected for solid fuel clean out.Type: GrantFiled: July 17, 2023Date of Patent: February 25, 2025Assignee: WH PRODUCTS, LLCInventors: Paul J. Simon, Michael R. Giebel, Xianjia Fan
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Publication number: 20250062869Abstract: A base station may generate and transmit a transport stream including a sequence of frames. A frame may include a plurality of partitions, where each partition includes a corresponding set of OFDM symbols. For each partition, the OFDM symbols in that partition may have a corresponding cyclic prefix size and a corresponding FFT size, allowing different partitions to be targeted for different collections of user devices, e.g., user devices having different expected values of maximum delay spread and/or different ranges of mobility. The base station may also dynamically re-configure the sample rate of each frame, allowing further resolution in control of subcarrier spacing. By allowing the cyclic prefixes of different OFDM symbols to have different lengths, it is feasible to construct a frame that confirms to a set payload duration and has arbitrary values of cyclic prefix size per partition and FFT size per partition. The partitions may be multiplexed in time and/or frequency.Type: ApplicationFiled: August 26, 2024Publication date: February 20, 2025Applicant: One Media, LLCInventors: Michael J. SIMON, Kevin A. SHELBY, Mark EARNSHAW
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Publication number: 20250058106Abstract: Methods and devices are provided for the non-invasive treatment of diseases or disorders, such as Alzheimer's disease, Parkinson's disease, rheumatoid arthritis (RA), multiple sclerosis, postoperative cognitive dysfunction, or postoperative delirium. A device comprises a stimulator having an electrode configured for contacting an outer skin surface of a neck of the patient and an energy source configured to transmit, via the electrode, an electric current transcutaneously and non-invasively through the outer skin surface of the neck of the patient to generate an electrical impulse at or near a vagus nerve within the patient. The electrical impulse comprises bursts of 2 to 20 pulses with each of the bursts comprising a frequency from about 15 Hz to about 50 Hz and with each of the pulses comprising a duration from about 20 microseconds to about 1000 microseconds.Type: ApplicationFiled: November 7, 2024Publication date: February 20, 2025Applicant: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
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Patent number: 12225555Abstract: A method disclosed includes receiving data from a plurality of data sources in a broadcast core network for transmission over a radio access network (RAN). The method includes assigning radio spectrum resources for transmitting the data over the RAN according to a policy guidance set by a plurality of network operators for sharing the radio spectrum resources and generating a baseband packet corresponding to the data at a distributed unit (DU) in the RAN. The method includes collecting transmission data from a plurality of user equipments (UEs) in the RAN for training a machine learning algorithm and scheduling transmission of the generated baseband packet to a remote unit (RU) over a fronthaul in a radio topology of a plurality of radio topologies under control of the machine learning algorithm according to the policy guidance. The generated baseband packet is compatible for transmission in the plurality of radio technologies.Type: GrantFiled: February 11, 2022Date of Patent: February 11, 2025Assignee: SINCLAIR BROADCAST GROUP, INC.Inventors: Michael J. Simon, Mark A. Aitken, Ebenezer K. Kofi, Louis Herbert Libin