Abstract: Devices, systems and methods are disclosed for treating a variety of diseases and disorders. A device for treating a disorder in a patient comprises a housing having a contact surface for contacting an outer skin surface of the patient and an energy source within the housing. The energy source is configured to transmit electrical impulses through the outer skin surface of the patient to a selected nerve within the patient. The electrical impulses include bursts of pulses having a burst frequency between 1 Hz and 5000 Hz and a burst duration between 100 microseconds and 20,000 microseconds.

Abstract: Techniques are disclosed relating to generating and receiving radio frames with multiple portions that have different target geographic areas. A data frame may include a first partition that includes a physical layer encoding of first data to be transmitted in a first geographic area, where the first geographic area is defined by a first threshold distance from the one or more transmitters. The data frame may include a second that includes a physical layer encoding of second data to be transmitted in a second geographic area, where the second geographic area is defined by a second, greater threshold distance from the one or more transmitters.

Abstract: Cancer is treated using coordinated treatment regimens that uses various compounds and compositions that drive a tumor from the escape phase of cancer immunoediting to the elimination and equilibrium phase of cancer immunoediting.

Abstract: A pellet fueled apparatus having a continuous spark ignition system and swing-away warming rack is disclosed. The apparatus may include a power supply controller configured to cause a spark generator to create a continuous spark in a gap space between two electrodes for a duration greater than 2 seconds and up to 20 minutes uninterrupted. The apparatus, when embodied as a grill may include a warming rack that swings away from an underlying cooking surface when the grill lid is opened.

Abstract: Systems and methods are provided for treating blood clots associated with a replicating pathogen, such as a virus in the coronaviridae family. The methods include emitting an electrical impulse near a vagus nerve within the patient sufficient to inhibit or reduce an inflammatory or allergic response in the patient, provide relief for bronchoconstriction that results in the tightening of airways and the inability to breath without ventilator support and/or lessen the abnormal blot clotting that develops in some patients. The systems and methods are particularly useful for treating post-COVID conditions or post-acute sequelae of COVID-19 that develop in “long-haul” or COVID patients.

Abstract: Devices, systems and methods are disclosed for treating or preventing an autism spectrum disorder, a pervasive developmental disorder, or a disorder of psychological development. The methods comprise transmitting impulses of energy non-invasively to selected nerve fibers, particularly those in a vagus nerve. The nerve stimulation may be used as a behavior conditioning tool, by producing euphoria in an autistic individual. Vagus nerve stimulation is also used to modulate circulating serotonin levels in a pregnant woman so as to reduce the risk of having an autistic child; modulate the levels of growth factors within a child; promote balance of neuronal excitation/inhibition; modulate the activity of abnormal resting state neuronal networks; increase respiratory sinus arrhythmia; and avert episodes of motor stereotypies with the aid of forecasting methods.

Abstract: The invention relates to methods and reagents for analyzing samples for the presence of JC virus antibodies.

Abstract: Provided herein are compositions that include a single nucleic acid vector or two different nucleic acid vectors, and the use of these compositions to treat hearing loss in a subject.

Abstract: Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and/or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and/or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.

Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical non-invasive stimulation of a nerve, such as the trigeminal nerve. A nerve stimulator is configured for coupling to a mobile device configured to receive a wireless signal, such as a mobile phone. The stimulator is further configured to generate an electrical impulse and to transmit the electrical impulse through one or more electrodes and the outer skin surface of the forehead of the patient to modulate the nerve within the patient.

Abstract: A cooking utensil having a handle and a rigid metal scraper head connected to the handle is disclosed. The scraper head may include a squeegee blade holder formed thereon, or attached thereto. A squeegee blade may be securely disposed in the squeegee blade holder.

Abstract: Systems and methods for remote therapy and patient monitoring are provided. A method comprises contacting an outer skin surface of a patient with a contact surface of a stimulator and transmitting an electrical impulse from the stimulator transcutaneously through the outer skin surface to a nerve within the patient. Data related to parameters of the electrical impulse applied to the nerve is stored and transmitted to a remote source. The data may include duration of treatment, amplitude of the electrical impulse, compliance with a prescribed therapy regimen or other relevant data related to the therapy. The method may further include collecting patient status data, such as symptoms of a medical condition (e.g., severity of a headache) before, during and/or after stimulation. The patient status data is correlated with the treatment data to monitor compliance and/or the effectiveness of the therapy.

Abstract: A solid pellet fueled apparatus for imparting a smoke flavor to food items is disclosed. The apparatus may include an enclosed housing having an upper food chamber and a lower drawer. The lower drawer may include a pan for receiving water ice and a pellet burning system. Cool smokey air generated by the contents of the lower drawer rises through the food chamber to impart a smoke flavor to food.

Abstract: Devices, systems and methods are disclosed for treating or preventing gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders. The methods comprise transmitting impulses of energy non-invasively to selected nerve fibers, particularly those in a vagus nerve. The methods provide damaged interstitial cells of Cajal (ICC) with trophic factors via vagal afferent nerve fibers, thereby reversing ICC damage, and as a consequence improving gastric motility. The methods also increase levels of inhibitory neurotransmitters in the brain so as to decrease neural activity within the area postrema, or they deactivate a resting state neural network containing parts of the anterior insula and anterior cingulate cortex, which will thereby reduce abnormal interoception and visceral hypersensitivity.

Abstract: A solid pellet fueled heater having a base unit with forced air blowers and a dual tube chimney structure is disclosed. The dual tube chimney structure may be used to warm incoming air for distribution around the heater. The pellet heater may also include a dual auger system and multi/high speed auger motor. The dual auger may include first and second auger blades mounted on a single auger shaft having blade pitches configured to convey solid fuel in opposite directions.

Abstract: Systems and methods are provided for modulating one or more nerves within patients. A method comprises generating a signal comprising an electrical impulse and contacting an interface with an outer skin surface of a patient. The electrical impulse is delivered from one or more electrode(s) through the interface and the outer skin surface of the patient to a vagus nerve, thereby modulating the vagus nerve sufficiently to treat a medical condition. The one or more electrode(s) are spaced from the interface by a distance of about 0.25 to about 4 times an outer dimension of the interface.

Abstract: Some aspects of this disclosure are direct to a system that includes a first scheduler configured to receive an input packet and generate a first packet to be transmitted using a first radio unit (RU). The system further includes a second scheduler configured to receive the first packet from the first scheduler and generate a second packet. The second packet is to be transmitted using a second RU. The system further includes a first fronthaul operated using evolved Common Public Radio Interface (eCPRI) protocol and configured to direct the first packet to the first RU to be transmitted on a first channel having a first frequency. The system further includes a second fronthaul operated using the eCPRI protocol and configured to direct the second packet to the second RU to be transmitted on a second channel having a second frequency different from the first frequency.

Abstract: A battery-operated wireless control system for outdoor cooking and heating appliances is disclosed. The system may include an electronic controller paired to a wireless temperature probe and a wireless monitor device capable of storing and recharging the wireless temperature probe. The electronic controller may control the operation of a fuel supply assembly, a fan assembly, and a spark generating assembly included in the appliance.

Abstract: Systems, devices and methods are provided for delivering electrical impulses to the vagus nerve to inhibit the reduction of telomere lengths in cellular DNA, thereby potentially increasing an individual's longevity and/or healthspan. A method comprises positioning a contact surface of a device in contact with an outer skin surface of a patient. An electrical impulse is applied transcutaneously from the device through the outer skin surface of the patient to a vagus nerve in the patient according to a stimulation protocol. The stimulation protocol includes at least two doses administered each day for a plurality of day. The doses each have a duration of about 60 seconds to about 5 minutes, preferably about 90 seconds to 3 minutes. The electrical impulse and the stimulation protocol are sufficient to modulate the vagus nerve such that such that the rate of telomere shortening in the patient's cellular DNA is reduced.

Abstract: An example method of mapping a plurality of modulation symbols of a plurality of physical layer pipes present in a frame to a resource grid of data cells for the frame is described. The modulation symbols of the plurality of physical layer pipes are represented by a two-dimensional array comprising the modulation symbol values for the plurality of physical layer pipes and the resource grid of data cells is represented by a one-dimensional sequentially indexed array.