Abstract: An approach for providing diagnostic information regarding one or more impacts sustained by one or more users while the one or more users are participating in a team activity is described. A diagnostic platform detects one or more impacts sustained by a user, wherein the user is part of a team with one or more other users engaged in a team activity. The diagnostic platform generates a recommendation for a level of participation of the user, the one or more other users, or a combination thereof in the team activity based on the one or more impacts, a severity level of the one or more impacts, or a combination thereof. The diagnostic platform further presents the recommendation, a representation of the severity level, a representation of the level of participation, or a combination thereof in a user interface.

Abstract: An approach for monitoring a sleeping subject includes receiving an input for specifying an attachment position of a monitoring device attached to a subject, calibrating a resting positioning of the subject based on the attachment position, analyzing sensor information collected from the monitoring device to determine a movement of the subject into a potentially dangerous position with respect to the calibrated resting position, wherein the monitoring device includes an array of sensors including an accelerometer, one or more biometric sensors, or a combination thereof.

Abstract: Devices and systems are disclosed for the non-invasive treatment of medical conditions through delivery of energy to target tissue, comprising a source of electrical power, a magnetically permeable toroidal core, and a coil that is wound around the core. The coil and core are embedded in a continuous electrically conducting medium, which is adapted to have a shape that conforms to the contour of an arbitrarily oriented target body surface of a patient. The conducting medium is applied to that surface by any of several disclosed methods, and the source of power supplies a pulse of electric charge to the coil, such that the coil induces an electric current and/or an electric field within the patient, thereby stimulating tissue and/or one or more nerve fibers within the patient. The invention shapes an elongated electric field of effect that can be oriented parallel to a long nerve. In one embodiment, the device comprises two toroidal cores that lie adjacent to one another.

Abstract: An approach for providing personalized information regarding one or more physiological conditions associated with a user is described. A personal health platform calculates a minimum value, a maximum value, or a combination thereof for a physiological condition of a user. The personal health platform senses a measured value for the physiological condition from the user. The personal health platform further presents a user interface depicting the measured value relative to the minimum value, the maximum value, a historical measured value for the user, or a combination thereof, wherein the user interface depicts the measured value, the minimum value, the maximum value, or a combination thereof on one or more ring-based graphical elements, and wherein the one or more ring-based graphical elements correspond to a measurement range for the physiological condition.

Abstract: The present invention includes methods and devices for treating hypotension, such as in cases of shock, including septic shock, anaphylactic shock and hypovolemia. The method includes the step of applying at least one electrical impulse to at least one selected region of a parasympathetic nervous system of the patient. The electrical impulse is sufficient to modulate one or more nerves of the parasympathetic nervous system to increase the ratio of blood pressure to heart rate and relieve the condition and/or extend the patient's life.

Abstract: Non-invasive electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including sinus symptoms that resemble an immune-mediated response (“sinus” headaches), irrespective of whether those symptoms arise from an allergy that is co-morbid with the headache. The disclosed methods may also be used to treat other disorders that may be co-morbid with migraine headaches, such as anxiety disorders. In preferred embodiments of the disclosed methods, one or both of the patient's vagus nerves are stimulated non-invasively. In other embodiments, parts of the sympathetic nervous system and/or the adrenal glands are stimulated.

Abstract: Devices, systems and methods are disclosed that are used to treat a medical condition, by electrical stimulation of a nerve or nerve ganglion, used in conjunction with biofeedback. The system comprises a stimulator that applies electrical impulses sufficient to modulate a nerve at a target site within the patient. A sensor measures a physiological output from the patient, such as heart rate variability, and a property of the stimulation signal is varied based on the physiological output.

Abstract: Monoclonal antibodies that specifically bind to M.96. Also included are methods of using these antibodies to treat mammals having or at risk of having 006-mediated diseases, or to diagnose % Q mediated diseases.

Abstract: Devices, systems and methods for treating bronchoconstriction associated with asthma, anaphylaxis or chronic obstructive pulmonary disease. The treatment comprises transmitting impulses of energy non-invasively to selected nerve fibers that are responsible for smooth muscle dilation, such as the vagus nerve.

Abstract: Devices, systems and methods for applying electrical impulse(s) to one or more selected nerves are described. An electrical stimulator is introduced through a to a target location within, adjacent to, or in close proximity with, the carotid sheath. The stimulator has an antenna that allows it to be powered solely by far-field or approximately plane wave electromagnetic radiation, having frequencies in the range of 0.3 to 10 GHz. Electrical impulses are applied through the stimulator to a vagus nerve to stimulate, block or otherwise modulate activity of the nerve and treat the patient's condition. The stimulator uses an adjustable number of fixed voltage (or fixed current) pulses with fixed duration to elicit desired changes in nerve response, the timing of which are controlled by an external power transmitter and controller.

Abstract: Non-invasive electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including sinus symptoms that resemble an immune-mediated response (“sinus” headaches), irrespective of whether those symptoms arise from an allergy that is co-morbid with the headache. The disclosed methods may also be used to treat other disorders that may be co-morbid with migraine headaches, such as anxiety disorders. In preferred embodiments of the disclosed methods, one or both of the patient's vagus nerves are stimulated non-invasively. In other embodiments, parts of the sympathetic nervous system and/or the adrenal glands are stimulated.

Abstract: Non-invasive electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including sinus symptoms that resemble an immune-mediated response (“sinus” headaches), irrespective of whether those symptoms arise from an allergy that is co-morbid with the headache. The disclosed methods may also be used to treat other disorders that may be co-morbid with migraine headaches, such as anxiety disorders. In preferred embodiments of the disclosed methods, one or both of the patient's vagus nerves are stimulated non-invasively. In other embodiments, parts of the sympathetic nervous system and/or the adrenal glands are stimulated.

Abstract: Disclosed is a system for servers to redirect client requests to other servers in order to distribute client traffic among the servers. A client is assigned to a server although the client may be unaware of that assignment. When the client accesses a server, a server possibly identified to the client by a name service, the server checks the client's assignment. If the client is not assigned to this server, then in some scenarios this server redirects the client to its assigned server. The client responds by sending its request to the assigned server. In other scenarios, the first server accessed by the client proxies the client's traffic to the assigned server. A database is kept of client-to-server assignments. If the present load distribution is less than ideal (e.g., clients are assigned to an unavailable server), then the assignment database is updated to reflect how the load should be distributed.

Abstract: A debris grinder interfaces directly with a typical roll-off container and a typical roll-off truck. By interfacing to the roll-off container, there is no need to feed waste by hand—an operation that is often dangerous to those operating the equipment. By interfacing with a typical roll-off truck, the debris grinder becomes mobile for spreading of the ground debris into the soil around the construction site. The debris grinder includes a skid portion for supporting and holding the roll-off container, a grinder portion for grinding debris from the roll-off container and depositing the ground-up debris onto the soil at the job site.

Abstract: The present invention is in the fields of cell biology, immunology and oncology. The invention provides humanized antibodies that recognize ?v?6 integrins, which antibodies comprise a variable region of nonhuman origin and at least a portion of an immunoglobulin of human origin. The invention also provides methods for preparation of such antibodies, pharmaceutical compositions comprising them, and methods of treating, diagnosing and/or preventing various diseases and disorders by administering the humanized anti-?v?6 antibodies of the invention. The invention also relates to the identification of differential expression of the integrin ?v?6 on the surfaces of tumor cells and tissues, the use of this differential expression in determining the metastatic potential of tumor cells, and methods of diagnosis and treatment/prevention of tumor metastasis and for elimination of residual metastatic tumor cells using ligands, particularly antibodies, that bind to integrin ?v?6.

Abstract: In a next generation broadcast architecture, a broadcast gateway may send segments of a data file to a broadcast transmission system and to a server. The broadcast transmission system wirelessly transmits the segments to a user equipment (UE) device. When the UE device fails to decode a segment, it sends a request for re-transmission of the segment to the server via an IP network. The server re-transmits the requested segment to the UE device via the IP network. Furthermore, the gateway may receive one or more IP data flows (e.g., video streams) having variable bit rate. The gateway may apply dynamically-variable coding to the IP data flows so that the resulting coded IP data flows have an aggregate bit rate that matches a constant physical transport rate of the broadcast transmission system.

Abstract: Binding agents able to disrupt bacterial biofilms of diverse origin are described, including monoclonal antibodies secreted by human B lymphocytes. Methods to prevent formation of or to dissolve biofilms with these binding agents are also described. Immunogens for eliciting antibodies to disrupt biofilms are also described.

Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical noninvasive stimulation of a vagus nerve. The system comprises a handheld stimulator that is applied to the surface of the patient's neck, wherein the stimulator comprises or is joined to a smartphone. A camera of the smartphone may be used to position and reposition the stimulator to a particular location on the patient's neck. The system may also comprise a base station that is used to meter the charging of a rechargeable battery within the stimulator. The base station and stimulator transmit data to one another regarding the status of a stimulation session.

Abstract: Devices and systems are disclosed for the non-invasive treatment of medical conditions through delivery of energy to target tissue, comprising a source of electrical power, a magnetically permeable toroidal core, and a coil that is wound around the core. The coil and core are embedded in a continuous electrically conducting medium, which is adapted to have a shape that conforms to the contour of an arbitrarily oriented target body surface of a patient. The conducting medium is applied to that surface by any of several disclosed methods, and the source of power supplies a pulse of electric charge to the coil, such that the coil induces an electric current and/or an electric field within the patient, thereby stimulating tissue and/or one or more nerve fibers within the patient. The invention shapes an elongated electric field of effect that can be oriented parallel to a long nerve. In one embodiment, the device comprises two toroidal cores that lie adjacent to one another.