Abstract: Disclosed herein are an N-(pyrazolylmethyl)arylsulfonamide derivative useful as a calcium ion channel blocker, a pharmaceutically acceptable salt thereof, and the medicinal use thereof as a therapeutic agent using its calcium ion channel blocking effect.

Abstract: A thin film transistor substrate with an adhesive strength between a semiconductor layer and a source electrode, and between a semiconductor layer and a drain electrode; and an LCD device using the thin film transistor substrate. The thin film transistor substrate includes a substrate, a gate electrode on the substrate, a gate insulating film on the gate electrode, an active layer on the gate insulating film, an ohmic contact layer on the active layer, a barrier layer on the ohmic contact layer. The barrier layer is formed of a material layer containing Ge. A source electrode and a drain electrode are on the barrier layer. The source and drain electrodes are provided at a predetermined interval from each other.

Abstract: Disclosed herein are an N-(pyrazolylmethyl)arylsulfonamide derivative useful as a calcium ion channel blocker, a pharmaceutically acceptable salt thereof, and the medicinal use thereof as a therapeutic agent using its calcium ion channel blocking effect.

Abstract: A color filter substrate includes a substrate in which a plurality of pixel areas are defined; a black matrix formed on the substrate, and having a plurality of openings in correspondence to the pixel areas; a color filter layer formed on the substrate, and including a red color filter, a green color filter, and a blue color filter that are sequentially arranged in a first direction in correspondence to the pixel areas; and a plurality of first column spacers and a plurality of second column spacers formed over the black matrix, and having different heights, wherein a height of each of the first column spacers is higher than a height of each of the second column spacers, and an arrangement density of the first column spacers is lower than an arrangement density of the second column spacers.

Abstract: An array substrate includes a substrate; gate lines over the substrate along a first direction; data lines over the substrate along a second direction and crossing the gate lines to define pixel regions; a thin film transistor at each crossing portion of the gate and data lines; an insulating layer covering the thin film transistor and having a flat top surface; a common electrode on the insulating layer all over the substrate; a common line on the common electrode; a passivation layer on the common line; and a pixel electrode on the passivation layer in each pixel region and connected to the thin film transistor, the pixel electrode including electrode patterns, wherein the passivation layer has a step height at a top surface of the passivation layer due to the plurality of common lines.

Abstract: Novel benzoarylureido compounds and a use thereof for prevention and/or treatment of the neurodegenerative brain disease are provided. The neurodegenerative brain diseases may include Alzheimer's disease, dementia, Parkinson's disease, stroke, amyloidosis, Pick's disease, Lou Gehrig's disease, Huntington's disease, Creutzfeld-Jakob disease, and the like.

Abstract: The present invention relates to a method for preparing tetrabenazine (TBZ) and dihydrotetrabenazine (DTBZ), and more specifically to a method for preparing tetrabenazine (TBZ) and dihydrotetrabenazine (DTBZ) by using simple and short reaction processes of using 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 4-methyl-2-(3-(trimethylsilyl)prop-1-ene-2-yl)pentane as starting materials to sequentially perform an alkylation reaction, an Aza-Prins cyclization reaction in the presence of an oxidant and an oxidation reaction.

Abstract: Provided is a 2-(substituted ethynyl)quinoline derivative having an mGluR5 antagonistic activity and pharmaceutically acceptable salts thereof. The compound of the present invention can be useful as a medicament for treating and preventing mGluR5 receptor-mediated diseases such as Alzheimer's disease, senile dementia, Parkinson's disease, L-DOPA-induced dyskinesia, Huntington's chorea, amyotrophic lateral sclerosis, multiple sclerosis, schizophrenia, anxiety disorder, depression, neuropathic pain, drug dependence, fragile X syndrome, autism, migraine and gastroesophageal reflux disease (GERD).

Abstract: A liquid crystal display device includes an array substrate including: gate and data lines crossing each other on a first substrate to define a pixel region; a common line in parallel with the gate line; first and second common line patterns extending from the common line, wherein the data line is between the first and second common line patterns; a thin film transistor connected to the gate and data lines; a pixel electrode connected to the thin film transistor and in the pixel region; and an inorganic black matrix below the gate line, the common line, and the first and second common lines, wherein the inorganic black matrix below the first and second common lines shields the data line; an opposing substrate including a common electrode on a second substrate; and a liquid crystal layer between the array substrate and the opposing substrate.

Abstract: An array substrate for a liquid crystal display device includes a substrate, a gate line and a data line on the substrate and crossing each other to define a pixel region, a thin film transistor connected to the gate line and the data line, a first passivation layer on the thin film transistor and having a first unevenness structure at its top surface, an auxiliary unevenness layer on the first passivation layer and having a first roughness structure at its top surface, and a reflector on the auxiliary unevenness layer, the reflector having a second unevenness structure due to the first unevenness structure of the first passivation layer and a second roughness structure due to the first roughness structure of the auxiliary unevenness layer, the second roughness structure having smaller patterns than the second unevenness structure.

Abstract: An array substrate for a liquid crystal display device includes: a substrate; a gate line and a data line on the substrate; a common line parallel to and spaced apart from the gate line; a thin film transistor connected to the gate line and the data line; a plurality of pixel electrodes in the pixel region; a plurality of common electrodes alternating with the plurality of pixel electrodes; at least one outermost common electrode at an edge portion of the pixel region; a black matrix corresponding to the thin film transistor, the gate line and the data line, the black matrix including an inorganic material and having an open portion; and a color filter layer in the open portion.

Abstract: An array substrate for a liquid crystal display device includes a substrate, a gate line and a data line on the substrate and crossing each other to define a pixel region, a thin film transistor connected to the gate line and the data line, a first passivation layer on the thin film transistor and having a first unevenness structure at its top surface, an auxiliary unevenness layer on the first passivation layer and having a first roughness structure at its top surface, and a reflector on the auxiliary unevenness layer, the reflector having a second unevenness structure due to the first unevenness structure of the first passivation layer and a second roughness structure due to the first roughness structure of the auxiliary unevenness layer, the second roughness structure having smaller patterns than the second unevenness structure.

Abstract: Provided is a 2-(substituted ethynyl)quinoline derivative having an mGluR5 antagonistic activity and pharmaceutically acceptable salts thereof. The compound of the present invention can be useful as a medicament for treating and preventing mGluR5 receptor-mediated diseases such as Alzheimer's disease, senile dementia, Parkinson's disease, L-DOPA-induced dyskinesia, Huntington's chorea, amyotrophic lateral sclerosis, multiple sclerosis, schizophrenia, anxiety disorder, depression, neuropathic pain, drug dependence, fragile X syndrome, autism, migraine and gastroesophageal reflux disease (GERD).

Abstract: An array substrate includes a substrate; gate lines over the substrate along a first direction; data lines over the substrate along a second direction and crossing the gate lines to define pixel regions; a thin film transistor at each crossing portion of the gate and data lines; an insulating layer covering the thin film transistor and having a flat top surface; a common electrode on the insulating layer all over the substrate; a common line on the common electrode; a passivation layer on the common line; and a pixel electrode on the passivation layer in each pixel region and connected to the thin film transistor, the pixel electrode including electrode patterns, wherein the passivation layer has a step height at a top surface of the passivation layer due to the plurality of common lines.

Abstract: An array substrate for a liquid crystal display device includes a substrate, a gate line and a data line on the substrate and crossing each other to define a pixel region, a thin film transistor connected to the gate line and the data line, a first passivation layer on the thin film transistor and having a first unevenness structure at its top surface, an auxiliary unevenness layer on the first passivation layer and having a first roughness structure at its top surface, and a reflector on the auxiliary unevenness layer, the reflector having a second unevenness structure due to the first unevenness structure of the first passivation layer and a second roughness structure due to the first roughness structure of the auxiliary unevenness layer, the second roughness structure having smaller patterns than the second unevenness structure.

Abstract: A liquid crystal display device includes an array substrate including: gate and data lines crossing each other on a first substrate to define a pixel region; a common line in parallel with the gate line; first and second common line patterns extending from the common line, wherein the data line is between the first and second common line patterns; a thin film transistor connected to the gate and data lines; a pixel electrode connected to the thin film transistor and in the pixel region; and an inorganic black matrix below the gate line, the common line, and the first and second common lines, wherein the inorganic black matrix below the first and second common lines shields the data line; an opposing substrate including a common electrode on a second substrate; and a liquid crystal layer between the array substrate and the opposing substrate.

Abstract: A color filter substrate includes a substrate in which a plurality of pixel areas are defined; a black matrix formed on the substrate, and having a plurality of openings in correspondence to the pixel areas; a color filter layer formed on the substrate, and including a red color filter, a green color filter, and a blue color filter that are sequentially arranged in a first direction in correspondence to the pixel areas; and a plurality of first column spacers and a plurality of second column spacers formed over the black matrix, and having different heights, wherein a height of each of the first column spacers is higher than a height of each of the second column spacers, and an arrangement density of the first column spacers is lower than an arrangement density of the second column spacers.

Abstract: An IPS mode LCD device is disclosed in which a common voltage drop and delay is decreased. The LCD includes gate and data lines crossing each other to define pixel regions. Thin film transistors are formed at crossing portions of the gate and data lines. Common lines are parallel with the gate lines and common electrodes project from the common lines parallel with the data lines. Pixel electrodes connected with drain electrodes of the thin film transistors are formed in the pixel regions between the parallel common electrodes. A first common voltage supplying line applies a first common voltage or a second common voltage to a closed circuit formed by grouping the adjacent odd numbered common lines. A second common voltage supplying line applies the second common voltage or the first common voltage to a closed circuit formed by grouping the adjacent even numbered common lines.

Abstract: A liquid crystal display device includes a display panel including a display area and a non-display area surrounding the display area, a plurality of gate lines and data lines arranged on the display area to intersect each other, so as to define a plurality of pixel regions, a plurality of thin-film transistors formed at respective intersections of the gate lines and the data lines, a plurality of pixel electrodes formed on the respective pixel regions and connected to the thin film transistors, and at least one first common line provided between the data lines and arranged parallel to the data lines.

Abstract: A liquid crystal display device includes an array substrate including: gate and data lines crossing each other on a first substrate to define a pixel region; a common line in parallel with the gate line; first and second common line patterns extending from the common line, wherein the data line is between the first and second common line patterns; a thin film transistor connected to the gate and data lines; a pixel electrode connected to the thin film transistor and in the pixel region; and an inorganic black matrix below the gate line, the common line, and the first and second common lines, wherein the inorganic black matrix below the first and second common lines shields the data line; an opposing substrate including a common electrode on a second substrate; and a liquid crystal layer between the array substrate and the opposing substrate.