Patents by Inventor Jakob Ley
Jakob Ley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130236472Abstract: The invention relates to certain compounds, salts of these compounds and mixtures containing or consisting of two or more such compounds, two or more such salts or one or more such compounds and one or more such salts, each for use in a method for the prophylaxis and/or treatment of inflammation, in particular of inflammation of the skin.Type: ApplicationFiled: February 27, 2013Publication date: September 12, 2013Applicant: Symrise AGInventors: Katharina Reichelt, Jakob Ley, Marcus Götz, Maria Blings
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Patent number: 8420151Abstract: The present invention relates to a mixture comprising or consisting of: (a) one or more inorganic salts which are suitable for nutrition and are not sodium chloride, (b) one or more mono- or polyvalent salts of polybasic food acids, (c) one or more amino acids, or salts thereof, which are suitable for nutrition.Type: GrantFiled: October 6, 2006Date of Patent: April 16, 2013Assignee: Symrise AGInventors: Jakob Ley, Guenter Kindel, Sylvia Muche, Kathrin Freiherr, Stefan Brennecke, Gerhard Krammer
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Patent number: 8318711Abstract: The invention relates to the use of 2,5-diacetyl-3a,5,6,6a-tetrahydro-6a-hydroxy-2,3a,5-trimethylfuro[2,3-d]-1,3-dioxole (diacetyl trimer) of the formula in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two or more of the stereoisomers (i) as an odoriferous or aromatic substance, (ii) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (iii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor, and/or (iv) for masking a bitter flavor. The invention furthermore relates to corresponding aromatic compositions as well as compositions which serve for nutrition, oral hygiene, consumption for pleasure or for oral pharmaceutical use.Type: GrantFiled: November 30, 2005Date of Patent: November 27, 2012Assignee: Symrise AGInventors: Ian Gatfield, Jakob Ley, Ingo Reiss, Günter Kindel, Gerhard Krammer
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Patent number: 8287934Abstract: The invention relates to the use of 5-acetyl-2,5-dimethyl-2-hydroxy-tetrahydrofuran-3-one (diacetyl dimer of formula (I)) in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two, three or four of its stereoisomers (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor; and/or (iii) as an aromatic and/or flavoring substance.Type: GrantFiled: May 7, 2007Date of Patent: October 16, 2012Assignee: Symrise AGInventors: Jakob Ley, Berthold Weber, Gerhard Krammer, Ingo Reiss, Heinz-Jürgen Bertram, Ian Gatfield, Petra Hoffmann-Lücke
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Patent number: 7919133Abstract: The present invention relates to the use of a compound of formula (I) or a mixture of compounds of formula (I) wherein: R1, R2, and R3 are independently H or an alkyl group having 1 to 3 C-atom, wherein at least one of R1, R2, and R3 is not H; R4 is H, an alkyl group having 1 to 6 C-atom, or an alkenyl group having 2 to 6 C-atom; R5, R6, R7, and R8 are independently H or methyl; and R9 is H, an alkyl group having 5 to 12 C-atoms, or an alkenyl group having 5 to 12 C-atoms; as a flavoring substance or mixture of flavoring substances.Type: GrantFiled: May 8, 2008Date of Patent: April 5, 2011Assignee: SYMRISE GmbH & Co. KGInventors: Jan Looft, Tobias Vössing, Jakob Ley, Michael Backes, Maria Blings
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Publication number: 20100331349Abstract: The use of ?-aminobutyric acid or a physiologically acceptable salt of ?-aminobutyric acid to mask or reduce the unpleasant flavour impression of an unpleasantly tasting substance is described. The food, beverage or oral care preparations or oral pharmaceutical preparations comprising at least one unpleasantly tasting substance and ?-aminobutyric acid are also described.Type: ApplicationFiled: March 29, 2005Publication date: December 30, 2010Inventors: Jakob Ley, Gunter Kindel, Gerhard Krammer, Thomas Hofmann, Nina Rotzoll
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Publication number: 20100233102Abstract: The invention provides the use of a 4-hydroxydihydrochalcone of the formula (I) wherein R1, R2, R3 and R4 each, independently, represent H, OH or O-alkyl, with the proviso that at least one of the groups R1, R2 or R3 represents OH, a salt of such a 4-hydroxydihydrochalcone of the formula (I), a mixture containing or consisting of two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above, a mixture containing or consisting of salts of two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above or a mixture containing or consisting of a 4-hydroxydihydrochalcone of the formula (I) or two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above, and a salt of a 4-hydroxydihydrochalcone of the formula (I) or two or more salts of different 4-hydroxydihydrochalcones of the formulaType: ApplicationFiled: March 21, 2007Publication date: September 16, 2010Applicant: SYMRISE GmbH & Co. KGInventors: Gerhard Krammer, Jakob Ley, Thomas Riess, Martin Haug, Susanne Paetz, Günter Kindel, Ralph Schmidtmann
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Publication number: 20100062030Abstract: The invention relates to the use of 5-acetyl-2,5-dimethyl-2-hydroxy-tetrahydrofuran-3-one (diacetyl dimer of formula (I)) in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two, three or four of its stereoisomers (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavour; and/or (iii) as an aromatic and/or flavouring substance.Type: ApplicationFiled: May 7, 2007Publication date: March 11, 2010Applicant: SYMRISE GmbH & Co., KGInventors: Jakob Ley, Berthold Weber, Gerhard Krammer, Ingo Reiss, Heinz-Jürgen Bertram, Ian Galfield, Petra Hoffmann-Lücke
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Publication number: 20090214728Abstract: The present invention relates to a mixture comprising or consisting of: (a) one or more inorganic salts which are suitable for nutrition and are not sodium chloride, (b) one or more mono- or polyvalent salts of polybasic food acids, (c) one or more amino acids, or salts thereof, which are suitable for nutrition.Type: ApplicationFiled: October 6, 2006Publication date: August 27, 2009Applicant: SYMRISE GmbH & Co. KGInventors: Jakob Ley, Guenter Kindel, Sylvia Muche, Kathrin Freiherr, Stefan Brennecke, Gerhard Krammer
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Publication number: 20090208426Abstract: The invention relates to the use of 2,5-diacetyl-3a,5,6,6a-tetrahydro-6a-hydroxy-2,3a,5-trimethylfuro[2,3-d]-1,3-dioxole (diacetyl trimer) of the formula in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two or more of the stereoisomers (i) as an odoriferous or aromatic substance, (ii) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (iii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavour, and/or (iv) for masking a bitter flavour. The invention furthermore relates to corresponding aromatic compositions as well as compositions which serve for nutrition, oral hygiene, consumption for pleasure or for oral pharmaceutical use.Type: ApplicationFiled: November 30, 2005Publication date: August 20, 2009Applicant: SYMRISE GMBH & CO. KGInventors: Ian Gatfield, Jakob Ley, Ingo Reiss, Günter Kindel, Gerhard Krammer
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Publication number: 20090124701Abstract: An individual alkamide and/or a mixture having two or more different alkamides, is disclosed for changing, masking or reducing the unpleasant flavor impression of an unpleasant-tasting substance or mixture of substances. The alkamide can be trans-pellitorine; cis-pellitorine; 2Z,4Z- or 2Z,4E-decadienoic acid-N-isobutylamide; 2E,4E-decadienoic acid-N-([2S]-2-methylbutyl)amide; 2E,4E-decadienoic acid-N-([2R]-2-methylbutylamide); 2E,4Z-decadienoic acid-N-(2-methylbutyl)amide; achilleamide; sarmentine; 2E- or 3E-decenoic acid-N-isobutylamide; 3E-nonenoic acid-N-isobutylamide; spilanthol; homospilanthol; 2E,6Z,8E-decatrienoic acid-N-([2R]-2-methylbutyl)amide; 2E- or 2Z-decen-4-oic acid-N-isobutylamide; ?-sanshool; ?-hydroxysanshool; ?-hydroxysanshool; ?-hydroxysanshool; ?-hydroxyisosanshool; ?-dehydrosanshool; ?-sanshool; bungeanool; isobungeanool; dihydrobungeanool; or tetrahydrobungeanool, or combinations thereof.Type: ApplicationFiled: November 6, 2008Publication date: May 14, 2009Applicant: SYMRISE GmbH & Co. KGInventors: Kathrin Langer, Jakob Ley, Gerald Reinders, Gunter Kindel, Gerhard Krammer
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Publication number: 20090028804Abstract: The invention relates to a method for finding and assessing agonists [and] antagonists of the aryl hydrocarbon receptor (Ah receptor; AhR), to the agonists and antagonists themselves and to uses thereof.Type: ApplicationFiled: November 28, 2006Publication date: January 29, 2009Applicant: SYMRISE GmbH & Co. KGInventors: Jean Krutmann, Martina Herrmann, Gabriele Vielhaber, Jakob Ley, Oskar Koch
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Patent number: 7482479Abstract: The invention describes a process for the production of 2E,4Z-decadienoic acid-N-isobutylamide (cis-pellitorine) and its use as a pungent principle and aromatic substance having a heat-generating effect, preferably in preparations used for foodstuffs, oral hygiene or luxury foodstuffs.Type: GrantFiled: June 20, 2003Date of Patent: January 27, 2009Assignee: Symrise GmbH & Co., KGInventors: Ian-Lucas Gatfield, Jakob Ley, Jan Foerstner, Gerhard Krammer, Arnold Machinek
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Publication number: 20080317923Abstract: The invention relates to an aroma composition for reducing or suppressing a bitter, astringent impression in the oral cavity, comprising (i) one or more salivatory aroma substances and/or flavorings and (ii) one or more particular bitterness-masking aroma substances and/or flavorings and optionally (iii) one or more further aroma substances, wherein preferably at least one aroma substance is an aroma substance which suppresses malodors and optionally (iv) one or more auxiliary substances or carriers.Type: ApplicationFiled: June 19, 2008Publication date: December 25, 2008Applicant: SYMRISE GmbH & Co. KGInventors: Jakob Ley, Kathrin Langer, Gerhard Krammer, Gerald Reinders, Gunter Kindel, Christian Nolte
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Publication number: 20080305052Abstract: The use of hesperetin of formula (I) is described wherein the hesperetin of formula (I) is in the form of a (2S)-enantiomer, (2R)-enantiomer or any desired mixture of the two enantiomers, a salt of hesperetin of formula (I), —a mixture comprising or consisting of two or more salts of the hesperetin of formula (I), or a mixture comprising or consisting of hesperetin of formula (I) and one or more salts of hesperetin of formula (I) for enhancing the sweet taste of a sweet-tasting substance or sweet olfactory impression of a flavouring which gives a sweet olfactory impression.Type: ApplicationFiled: July 25, 2006Publication date: December 11, 2008Applicant: SYMRISE GmbH & Co. KG.Inventors: Jakob Ley, Guenter Kindel, Susanne Paetz, Thomas Riess, Martin Haug, Ralph Schmidtmann, Gerhard Krammer
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Publication number: 20080292763Abstract: The present invention relates to the use of a compound of formula (I) or a mixture of compounds of formula (I) wherein: R1, R2, and R3 are independently H or an alkyl group having 1 to 3 C-atom, wherein at least one of R1, R2, and R3 is not H; R4 is H, an alkyl group having 1 to 6 C-atom, or an alkenyl group having 2 to 6 C-atom; R5, R6, R7, and R8 are independently H or methyl; and R9 is H, an alkyl group having 5 to 12 C-atoms, or an alkenyl group having 5 to 12 C-atoms; as a flavoring substance or mixture of flavoring substances.Type: ApplicationFiled: May 8, 2008Publication date: November 27, 2008Applicant: SYMRISE GmbH & Co. KGInventors: Jan Looft, Tobias Vossing, Jakob Ley, Michael Backes, Maria Blings
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Publication number: 20080242585Abstract: The use (i) of a compound of formula 2 wherein R3 and R4 independently of one another represent a C2-C4-alkyl or -alkenyl radical or (ii) of a mixture consisting of or comprising: at least one such compound of formula 2 as well as at least one compound of formula 1 and/or at least one compound of formula 3, wherein R1, R2, R3, R4, R5 and R6 independently of one another represent a C2-C4-alkyl or -alkenyl radical, as a fragrance or flavouring is described.Type: ApplicationFiled: September 9, 2005Publication date: October 2, 2008Applicant: SYMRISE GMBH & CO. KGInventors: Frank Ott, Gunter Kindel, Jakob Ley, Gehard Krammer, Claus-Oliver Schmidt, Peter Schieberle, Michael Granvogl
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Publication number: 20080242740Abstract: The invention primarily relates to aroma compositions of (i) certain saliva-stimulating alkamides having a tingling, pungent and/or hot flavor (such as for example pellitorines, spilanthol) with (ii) hesperetin (5,7-dihydroxy-3-(3-hydroxy-4-methoxyphenyl)-chroman-4-one) or the enantiomers and/or salts thereof and/or (iii) 4-hydroxydihydrochalcones (3-(4-hydroxyphenyl)-1-phenylpropan-1-ones) and/or the salts thereof, the use thereof to enhance the sweet flavor of sweet-tasting substances or the sweet odor impression of aroma substances which give rise to a sweet odor impression, but in particular to enhance the sweet initial flavor or odor (initial sweetness). The invention thus relates to the use of said aroma compositions as general sweetness enhancers and enhancers of initial sweetness.Type: ApplicationFiled: March 28, 2008Publication date: October 2, 2008Applicant: SYMRISE GmbH & Co. KGInventors: Jakob Ley, Kathrin Freiherr, Gerhard Krammer, Gerald Reinders
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Publication number: 20080227867Abstract: The use is described of the 4-hydroxychalcone derivatives of the formula (I) wherein A may represent a single or double bond, R1, R2 and R3, mutually independently, may in each case mean H, OH or (preferably C1-C4) alkoxy, providing that at least one of the residues R1 to R3 means OH, and R4 means H, OH or (preferably C1-C4) alkoxy, and/or (ii) the salts thereof and (iii) mixtures thereof to mask or reduce the unpleasant taste impression of an unpleasant tasting substance, as are corresponding methods and preparations.Type: ApplicationFiled: March 12, 2008Publication date: September 18, 2008Applicant: SYMRISE GmbH & Co. KGInventors: Jakob Ley, Susanne Paetz, Thomas Riess, Gerhard Krammer
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Publication number: 20080227866Abstract: The use of a hydroxyphenylalkadione derivative of the formula (I) wherein, for X, a and Y: X is a —CH2—, —NH— or —O— group, Y is a —CH2— group and a is a single bond or X and Y are in each case a —CH— group and a is a double bond in the Z or E configuration, wherein, for R1, R2 and R3 R1 denotes hydrogen, an aliphatic radical having 1 to 4 C atoms or a —O—R5, —S—R5 or —NR5R6 group and R2 and R3 independently of one another denote hydrogen or an alkyl having 1, 2, 3, 4 or 5 C atoms which is optionally substituted by one or more oxo groups or R7—O— groups or R1 and R2 together form an aliphatic ring which contains a total of 4 to 10 carbon atoms and 0 or 1 oxygen atom, wherein the ring constituent represented by R1 and R2 is optionally substituted by one or more oxo groups and/or R7—O— groups and/or aliphatic radicals having 1 to 4 C atoms and R3 denotes hydrogen or an alkyl having 1, 2, 3, 4 or 5 C atoms which is optionally substituted by one or more oxo groups or R7—O— groups or R2 andType: ApplicationFiled: June 27, 2006Publication date: September 18, 2008Applicant: SYMRISE GMBH & CO. KGInventors: Jakob Ley, Heinz-Jurgen Bertram, Gerhard E. Krammer, Gunter Kindel