Patents by Inventor Jakob Ley

Jakob Ley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130236472
    Abstract: The invention relates to certain compounds, salts of these compounds and mixtures containing or consisting of two or more such compounds, two or more such salts or one or more such compounds and one or more such salts, each for use in a method for the prophylaxis and/or treatment of inflammation, in particular of inflammation of the skin.
    Type: Application
    Filed: February 27, 2013
    Publication date: September 12, 2013
    Applicant: Symrise AG
    Inventors: Katharina Reichelt, Jakob Ley, Marcus Götz, Maria Blings
  • Patent number: 8420151
    Abstract: The present invention relates to a mixture comprising or consisting of: (a) one or more inorganic salts which are suitable for nutrition and are not sodium chloride, (b) one or more mono- or polyvalent salts of polybasic food acids, (c) one or more amino acids, or salts thereof, which are suitable for nutrition.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: April 16, 2013
    Assignee: Symrise AG
    Inventors: Jakob Ley, Guenter Kindel, Sylvia Muche, Kathrin Freiherr, Stefan Brennecke, Gerhard Krammer
  • Patent number: 8318711
    Abstract: The invention relates to the use of 2,5-diacetyl-3a,5,6,6a-tetrahydro-6a-hydroxy-2,3a,5-trimethylfuro[2,3-d]-1,3-dioxole (diacetyl trimer) of the formula in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two or more of the stereoisomers (i) as an odoriferous or aromatic substance, (ii) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (iii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor, and/or (iv) for masking a bitter flavor. The invention furthermore relates to corresponding aromatic compositions as well as compositions which serve for nutrition, oral hygiene, consumption for pleasure or for oral pharmaceutical use.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: November 27, 2012
    Assignee: Symrise AG
    Inventors: Ian Gatfield, Jakob Ley, Ingo Reiss, Günter Kindel, Gerhard Krammer
  • Patent number: 8287934
    Abstract: The invention relates to the use of 5-acetyl-2,5-dimethyl-2-hydroxy-tetrahydrofuran-3-one (diacetyl dimer of formula (I)) in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two, three or four of its stereoisomers (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor; and/or (iii) as an aromatic and/or flavoring substance.
    Type: Grant
    Filed: May 7, 2007
    Date of Patent: October 16, 2012
    Assignee: Symrise AG
    Inventors: Jakob Ley, Berthold Weber, Gerhard Krammer, Ingo Reiss, Heinz-Jürgen Bertram, Ian Gatfield, Petra Hoffmann-Lücke
  • Patent number: 7919133
    Abstract: The present invention relates to the use of a compound of formula (I) or a mixture of compounds of formula (I) wherein: R1, R2, and R3 are independently H or an alkyl group having 1 to 3 C-atom, wherein at least one of R1, R2, and R3 is not H; R4 is H, an alkyl group having 1 to 6 C-atom, or an alkenyl group having 2 to 6 C-atom; R5, R6, R7, and R8 are independently H or methyl; and R9 is H, an alkyl group having 5 to 12 C-atoms, or an alkenyl group having 5 to 12 C-atoms; as a flavoring substance or mixture of flavoring substances.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: April 5, 2011
    Assignee: SYMRISE GmbH & Co. KG
    Inventors: Jan Looft, Tobias Vössing, Jakob Ley, Michael Backes, Maria Blings
  • Publication number: 20100331349
    Abstract: The use of ?-aminobutyric acid or a physiologically acceptable salt of ?-aminobutyric acid to mask or reduce the unpleasant flavour impression of an unpleasantly tasting substance is described. The food, beverage or oral care preparations or oral pharmaceutical preparations comprising at least one unpleasantly tasting substance and ?-aminobutyric acid are also described.
    Type: Application
    Filed: March 29, 2005
    Publication date: December 30, 2010
    Inventors: Jakob Ley, Gunter Kindel, Gerhard Krammer, Thomas Hofmann, Nina Rotzoll
  • Publication number: 20100233102
    Abstract: The invention provides the use of a 4-hydroxydihydrochalcone of the formula (I) wherein R1, R2, R3 and R4 each, independently, represent H, OH or O-alkyl, with the proviso that at least one of the groups R1, R2 or R3 represents OH, a salt of such a 4-hydroxydihydrochalcone of the formula (I), a mixture containing or consisting of two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above, a mixture containing or consisting of salts of two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above or a mixture containing or consisting of a 4-hydroxydihydrochalcone of the formula (I) or two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above, and a salt of a 4-hydroxydihydrochalcone of the formula (I) or two or more salts of different 4-hydroxydihydrochalcones of the formula
    Type: Application
    Filed: March 21, 2007
    Publication date: September 16, 2010
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Gerhard Krammer, Jakob Ley, Thomas Riess, Martin Haug, Susanne Paetz, Günter Kindel, Ralph Schmidtmann
  • Publication number: 20100062030
    Abstract: The invention relates to the use of 5-acetyl-2,5-dimethyl-2-hydroxy-tetrahydrofuran-3-one (diacetyl dimer of formula (I)) in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two, three or four of its stereoisomers (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavour; and/or (iii) as an aromatic and/or flavouring substance.
    Type: Application
    Filed: May 7, 2007
    Publication date: March 11, 2010
    Applicant: SYMRISE GmbH & Co., KG
    Inventors: Jakob Ley, Berthold Weber, Gerhard Krammer, Ingo Reiss, Heinz-Jürgen Bertram, Ian Galfield, Petra Hoffmann-Lücke
  • Publication number: 20090214728
    Abstract: The present invention relates to a mixture comprising or consisting of: (a) one or more inorganic salts which are suitable for nutrition and are not sodium chloride, (b) one or more mono- or polyvalent salts of polybasic food acids, (c) one or more amino acids, or salts thereof, which are suitable for nutrition.
    Type: Application
    Filed: October 6, 2006
    Publication date: August 27, 2009
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jakob Ley, Guenter Kindel, Sylvia Muche, Kathrin Freiherr, Stefan Brennecke, Gerhard Krammer
  • Publication number: 20090208426
    Abstract: The invention relates to the use of 2,5-diacetyl-3a,5,6,6a-tetrahydro-6a-hydroxy-2,3a,5-trimethylfuro[2,3-d]-1,3-dioxole (diacetyl trimer) of the formula in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two or more of the stereoisomers (i) as an odoriferous or aromatic substance, (ii) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (iii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavour, and/or (iv) for masking a bitter flavour. The invention furthermore relates to corresponding aromatic compositions as well as compositions which serve for nutrition, oral hygiene, consumption for pleasure or for oral pharmaceutical use.
    Type: Application
    Filed: November 30, 2005
    Publication date: August 20, 2009
    Applicant: SYMRISE GMBH & CO. KG
    Inventors: Ian Gatfield, Jakob Ley, Ingo Reiss, Günter Kindel, Gerhard Krammer
  • Publication number: 20090124701
    Abstract: An individual alkamide and/or a mixture having two or more different alkamides, is disclosed for changing, masking or reducing the unpleasant flavor impression of an unpleasant-tasting substance or mixture of substances. The alkamide can be trans-pellitorine; cis-pellitorine; 2Z,4Z- or 2Z,4E-decadienoic acid-N-isobutylamide; 2E,4E-decadienoic acid-N-([2S]-2-methylbutyl)amide; 2E,4E-decadienoic acid-N-([2R]-2-methylbutylamide); 2E,4Z-decadienoic acid-N-(2-methylbutyl)amide; achilleamide; sarmentine; 2E- or 3E-decenoic acid-N-isobutylamide; 3E-nonenoic acid-N-isobutylamide; spilanthol; homospilanthol; 2E,6Z,8E-decatrienoic acid-N-([2R]-2-methylbutyl)amide; 2E- or 2Z-decen-4-oic acid-N-isobutylamide; ?-sanshool; ?-hydroxysanshool; ?-hydroxysanshool; ?-hydroxysanshool; ?-hydroxyisosanshool; ?-dehydrosanshool; ?-sanshool; bungeanool; isobungeanool; dihydrobungeanool; or tetrahydrobungeanool, or combinations thereof.
    Type: Application
    Filed: November 6, 2008
    Publication date: May 14, 2009
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Kathrin Langer, Jakob Ley, Gerald Reinders, Gunter Kindel, Gerhard Krammer
  • Publication number: 20090028804
    Abstract: The invention relates to a method for finding and assessing agonists [and] antagonists of the aryl hydrocarbon receptor (Ah receptor; AhR), to the agonists and antagonists themselves and to uses thereof.
    Type: Application
    Filed: November 28, 2006
    Publication date: January 29, 2009
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jean Krutmann, Martina Herrmann, Gabriele Vielhaber, Jakob Ley, Oskar Koch
  • Patent number: 7482479
    Abstract: The invention describes a process for the production of 2E,4Z-decadienoic acid-N-isobutylamide (cis-pellitorine) and its use as a pungent principle and aromatic substance having a heat-generating effect, preferably in preparations used for foodstuffs, oral hygiene or luxury foodstuffs.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: January 27, 2009
    Assignee: Symrise GmbH & Co., KG
    Inventors: Ian-Lucas Gatfield, Jakob Ley, Jan Foerstner, Gerhard Krammer, Arnold Machinek
  • Publication number: 20080317923
    Abstract: The invention relates to an aroma composition for reducing or suppressing a bitter, astringent impression in the oral cavity, comprising (i) one or more salivatory aroma substances and/or flavorings and (ii) one or more particular bitterness-masking aroma substances and/or flavorings and optionally (iii) one or more further aroma substances, wherein preferably at least one aroma substance is an aroma substance which suppresses malodors and optionally (iv) one or more auxiliary substances or carriers.
    Type: Application
    Filed: June 19, 2008
    Publication date: December 25, 2008
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jakob Ley, Kathrin Langer, Gerhard Krammer, Gerald Reinders, Gunter Kindel, Christian Nolte
  • Publication number: 20080305052
    Abstract: The use of hesperetin of formula (I) is described wherein the hesperetin of formula (I) is in the form of a (2S)-enantiomer, (2R)-enantiomer or any desired mixture of the two enantiomers, a salt of hesperetin of formula (I), —a mixture comprising or consisting of two or more salts of the hesperetin of formula (I), or a mixture comprising or consisting of hesperetin of formula (I) and one or more salts of hesperetin of formula (I) for enhancing the sweet taste of a sweet-tasting substance or sweet olfactory impression of a flavouring which gives a sweet olfactory impression.
    Type: Application
    Filed: July 25, 2006
    Publication date: December 11, 2008
    Applicant: SYMRISE GmbH & Co. KG.
    Inventors: Jakob Ley, Guenter Kindel, Susanne Paetz, Thomas Riess, Martin Haug, Ralph Schmidtmann, Gerhard Krammer
  • Publication number: 20080292763
    Abstract: The present invention relates to the use of a compound of formula (I) or a mixture of compounds of formula (I) wherein: R1, R2, and R3 are independently H or an alkyl group having 1 to 3 C-atom, wherein at least one of R1, R2, and R3 is not H; R4 is H, an alkyl group having 1 to 6 C-atom, or an alkenyl group having 2 to 6 C-atom; R5, R6, R7, and R8 are independently H or methyl; and R9 is H, an alkyl group having 5 to 12 C-atoms, or an alkenyl group having 5 to 12 C-atoms; as a flavoring substance or mixture of flavoring substances.
    Type: Application
    Filed: May 8, 2008
    Publication date: November 27, 2008
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jan Looft, Tobias Vossing, Jakob Ley, Michael Backes, Maria Blings
  • Publication number: 20080242585
    Abstract: The use (i) of a compound of formula 2 wherein R3 and R4 independently of one another represent a C2-C4-alkyl or -alkenyl radical or (ii) of a mixture consisting of or comprising: at least one such compound of formula 2 as well as at least one compound of formula 1 and/or at least one compound of formula 3, wherein R1, R2, R3, R4, R5 and R6 independently of one another represent a C2-C4-alkyl or -alkenyl radical, as a fragrance or flavouring is described.
    Type: Application
    Filed: September 9, 2005
    Publication date: October 2, 2008
    Applicant: SYMRISE GMBH & CO. KG
    Inventors: Frank Ott, Gunter Kindel, Jakob Ley, Gehard Krammer, Claus-Oliver Schmidt, Peter Schieberle, Michael Granvogl
  • Publication number: 20080242740
    Abstract: The invention primarily relates to aroma compositions of (i) certain saliva-stimulating alkamides having a tingling, pungent and/or hot flavor (such as for example pellitorines, spilanthol) with (ii) hesperetin (5,7-dihydroxy-3-(3-hydroxy-4-methoxyphenyl)-chroman-4-one) or the enantiomers and/or salts thereof and/or (iii) 4-hydroxydihydrochalcones (3-(4-hydroxyphenyl)-1-phenylpropan-1-ones) and/or the salts thereof, the use thereof to enhance the sweet flavor of sweet-tasting substances or the sweet odor impression of aroma substances which give rise to a sweet odor impression, but in particular to enhance the sweet initial flavor or odor (initial sweetness). The invention thus relates to the use of said aroma compositions as general sweetness enhancers and enhancers of initial sweetness.
    Type: Application
    Filed: March 28, 2008
    Publication date: October 2, 2008
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jakob Ley, Kathrin Freiherr, Gerhard Krammer, Gerald Reinders
  • Publication number: 20080227867
    Abstract: The use is described of the 4-hydroxychalcone derivatives of the formula (I) wherein A may represent a single or double bond, R1, R2 and R3, mutually independently, may in each case mean H, OH or (preferably C1-C4) alkoxy, providing that at least one of the residues R1 to R3 means OH, and R4 means H, OH or (preferably C1-C4) alkoxy, and/or (ii) the salts thereof and (iii) mixtures thereof to mask or reduce the unpleasant taste impression of an unpleasant tasting substance, as are corresponding methods and preparations.
    Type: Application
    Filed: March 12, 2008
    Publication date: September 18, 2008
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jakob Ley, Susanne Paetz, Thomas Riess, Gerhard Krammer
  • Publication number: 20080227866
    Abstract: The use of a hydroxyphenylalkadione derivative of the formula (I) wherein, for X, a and Y: X is a —CH2—, —NH— or —O— group, Y is a —CH2— group and a is a single bond or X and Y are in each case a —CH— group and a is a double bond in the Z or E configuration, wherein, for R1, R2 and R3 R1 denotes hydrogen, an aliphatic radical having 1 to 4 C atoms or a —O—R5, —S—R5 or —NR5R6 group and R2 and R3 independently of one another denote hydrogen or an alkyl having 1, 2, 3, 4 or 5 C atoms which is optionally substituted by one or more oxo groups or R7—O— groups or R1 and R2 together form an aliphatic ring which contains a total of 4 to 10 carbon atoms and 0 or 1 oxygen atom, wherein the ring constituent represented by R1 and R2 is optionally substituted by one or more oxo groups and/or R7—O— groups and/or aliphatic radicals having 1 to 4 C atoms and R3 denotes hydrogen or an alkyl having 1, 2, 3, 4 or 5 C atoms which is optionally substituted by one or more oxo groups or R7—O— groups or R2 and
    Type: Application
    Filed: June 27, 2006
    Publication date: September 18, 2008
    Applicant: SYMRISE GMBH & CO. KG
    Inventors: Jakob Ley, Heinz-Jurgen Bertram, Gerhard E. Krammer, Gunter Kindel