Patents by Inventor Jakob Ley
Jakob Ley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150259319Abstract: What are proposed are primarily aromatic alkenoic acid derivatives of the formula I for use in a therapeutic method as (a) means for reducing appetite and/or (b) means for causing a feeling of satiation and/or as (c) means for reducing energy intake and/or as (d) mood enhancers, and the non-therapeutic use of the aromatic alkenoic acid derivatives of formula I as (a) means for reducing appetite and/or (b) means for causing a feeling of satiation and/or as (c) means for reducing energy intake and/or as (d) mood enhancers.Type: ApplicationFiled: March 11, 2015Publication date: September 17, 2015Inventors: Jakob Ley, Katja Obst, Katharina Reichelt, Veronika Somoza, Barbara Rohm
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Patent number: 8906958Abstract: The invention relates to certain compounds, salts of these compounds and mixtures containing or consisting of two or more such compounds, two or more such salts or one or more such compounds and one or more such salts, each for use in a method for the prophylaxis and/or treatment of inflammation, in particular of inflammation of the skin.Type: GrantFiled: February 27, 2013Date of Patent: December 9, 2014Assignee: Symrise AGInventors: Katharina Reichelt, Jakob Ley, Marcus Götz, Maria Blings
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Patent number: 8828469Abstract: An individual alkamide and/or a mixture having two or more different alkamides, is disclosed for changing, masking or reducing the unpleasant flavor impression of an unpleasant-tasting substance or mixture of substances. The alkamide can be trans-pellitorine; cis-pellitorine; 2Z,4Z- or 2Z,4E-decadienoic acid-N-isobutylamide; 2E,4E-decadienoic acid-N-([2S]-2-methylbutyl)amide; 2E,4E-decadienoic acid-N-([2R]-2-methylbutylamide); 2E,4Z-decadienoic acid-N-(2-methylbutyl)amide; achilleamide; sarmentine; 2E- or 3E-decenoic acid-N-isobutylamide; 3E-nonenoic acid-N-isobutylamide; spilanthol; homospilanthol; 2E,6Z,8E-decatrienoic acid-N-([2R]-2-methylbutyl)amide; 2E- or 2Z-decen-4-oic acid-N-isobutylamide; ?-sanshool; ?-hydroxysanshool; ?-hydroxysanshool; ?-hydroxysanshool; ?-hydroxyisosanshool; ?-dehydrosanshool; ?-sanshool; bungeanool; isobungeanool; dihydrobungeanool; or tetrahydrobungeanool, or combinations thereof.Type: GrantFiled: November 6, 2008Date of Patent: September 9, 2014Assignee: Symrise AGInventors: Kathrin Langer, Jakob Ley, Gerald Reinders, Günter Kindel, Gerhard Krammer
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Publication number: 20140234412Abstract: Suggested are new compositions for oral ingestion, comprising at least one active agent from the group of alkamides. The compositions which are orally ingested reduce the uptake of free fatty acids in the adipocytes and at the same time stimulate the release of serotonin and dopamine, which leads to a reduction of appetite, a feeling of satiety and a positive mood. In doing so, the new compositions are thus perfectly suitable to counteract any undesired gain of weight.Type: ApplicationFiled: February 12, 2014Publication date: August 21, 2014Applicant: Symrise AGInventors: Jakob Ley, Sabine Widder, Veronika Somoza, Barbara Rohm, Matthias Zaunschirm, Gerhard Krammer
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Patent number: 8778987Abstract: The use is described of the 4-hydroxychalcone derivatives of the formula (I) wherein A may represent a single or double bond, R1, R2 and R3, mutually independently, may in each case mean H, OH or (preferably C1-C4) alkoxy, providing that at least one of the residues R1 to R3 means OH, and R4 means H, OH or (preferably C1-C4) alkoxy, and/or (ii) the salts thereof and (iii) mixtures thereof to mask or reduce the unpleasant taste impression of an unpleasant tasting substance, as are corresponding methods and preparations.Type: GrantFiled: March 12, 2008Date of Patent: July 15, 2014Assignee: Symrise AGInventors: Jakob Ley, Susanne Paetz, Thomas Riess, Gerhard Krammer
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Publication number: 20140170083Abstract: The invention relates to triterpenes and triterpene glycosides of the formula (I) and/or physiologically acceptable salts thereof, preferably naturally occurring triterpenes and triterpene glycosides from Mycetia balansae and/or physiologically acceptable salts thereof and orally consumable formulations comprising one or a plurality of these triterpenes and triterpene glycosides and/or physiologically acceptable salts thereof. The invention further relates to the use of these triterpenes and triterpene glycosides and/or physiologically acceptable salts thereof, preferably an extract of Mycetia balansae, for generating a sweet impression in an orally consumable formulation or for reinforcing the sweet impression of an orally consumable formulation comprising at least one further, preferably naturally occurring, sweet-tasting substance.Type: ApplicationFiled: June 1, 2012Publication date: June 19, 2014Applicant: Symrise AGInventors: Jakob Ley, Katharina Reichelt, Katja Obst, Ludger wessjohann, Sabine Wessjohann, Tran Van Sung, The Anh Nguyen, Ngo Van Trai
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Publication number: 20140134114Abstract: Preparations for oral consumption are proposed, comprising (a) lactic acid 1-menthyl ester of the general formula (I) its stereoisomers or mixtures thereof, (b) at least one substance having a bitter, astringent and/or metallic taste impression, and optionally (c) further flavourings.Type: ApplicationFiled: November 7, 2013Publication date: May 15, 2014Applicant: Symrise AGInventors: Gerhard Krammer, Jakob Ley, Katja Obst, Katharina Reichelt
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Patent number: 8679461Abstract: The use of hesperetin of formula (I) is described wherein the hesperetin of formula (I) is in the form of a (2S)-enantiomer, (2R)-enantiomer or any desired mixture of the two enantiomers, a salt of hesperetin of formula (I), —a mixture comprising or consisting of two or more salts of the hesperetin of formula (I), or a mixture comprising or consisting of hesperetin of formula (I) and one or more salts of hesperetin of formula (I) for enhancing the sweet taste of a sweet-tasting substance or sweet olfactory impression of a flavoring which gives a sweet olfactory impression.Type: GrantFiled: July 25, 2006Date of Patent: March 25, 2014Assignee: Symrise AGInventors: Jakob Ley, Guenter Kindel, Susanne Paetz, Thomas Riess, Martin Haug, Ralph Schmidtmann, Gerhard Krammer
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Publication number: 20130251730Abstract: Suggested is a compound of the formula (X) or any salt of a compound of the formula (X) or any mixture containing or consisting of two or more different compounds of the formula (X), two or more different salts of compounds of the formula (X) or one or more different compounds of the formula (X) and one or more different salts of compounds of the formula (X), wherein for R1, R2 and R3 independently of one another in every compound of the formula (X) the following applies: R1 means hydrogen or methyl, R2 means an organic residue with 5 carbon atoms and one oxygen atom or none and R3 means an organic residue with 10 carbon atoms and one or more oxygen atoms, or R1 and R2 together with the carbon atoms in positions 4 and 5 and the oxygen atom bound to the carbon atom in position 4 form a ring and comprise 5 carbon atoms and one oxygen atom or none, and R3 means an organic residue with 10 carbon atoms and one or more oxygen atoms, for use in a method for the prophylaxis and/or treatment of inflammation.Type: ApplicationFiled: March 1, 2013Publication date: September 26, 2013Applicant: Symrise AGInventors: Jakob Ley, Katharina Reichelt, Marcus Götz, Maria Blings, Veronika Somoza, Jessica Walker, Joel Michael Walker
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Publication number: 20130236472Abstract: The invention relates to certain compounds, salts of these compounds and mixtures containing or consisting of two or more such compounds, two or more such salts or one or more such compounds and one or more such salts, each for use in a method for the prophylaxis and/or treatment of inflammation, in particular of inflammation of the skin.Type: ApplicationFiled: February 27, 2013Publication date: September 12, 2013Applicant: Symrise AGInventors: Katharina Reichelt, Jakob Ley, Marcus Götz, Maria Blings
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Patent number: 8420151Abstract: The present invention relates to a mixture comprising or consisting of: (a) one or more inorganic salts which are suitable for nutrition and are not sodium chloride, (b) one or more mono- or polyvalent salts of polybasic food acids, (c) one or more amino acids, or salts thereof, which are suitable for nutrition.Type: GrantFiled: October 6, 2006Date of Patent: April 16, 2013Assignee: Symrise AGInventors: Jakob Ley, Guenter Kindel, Sylvia Muche, Kathrin Freiherr, Stefan Brennecke, Gerhard Krammer
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Patent number: 8318711Abstract: The invention relates to the use of 2,5-diacetyl-3a,5,6,6a-tetrahydro-6a-hydroxy-2,3a,5-trimethylfuro[2,3-d]-1,3-dioxole (diacetyl trimer) of the formula in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two or more of the stereoisomers (i) as an odoriferous or aromatic substance, (ii) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (iii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor, and/or (iv) for masking a bitter flavor. The invention furthermore relates to corresponding aromatic compositions as well as compositions which serve for nutrition, oral hygiene, consumption for pleasure or for oral pharmaceutical use.Type: GrantFiled: November 30, 2005Date of Patent: November 27, 2012Assignee: Symrise AGInventors: Ian Gatfield, Jakob Ley, Ingo Reiss, Günter Kindel, Gerhard Krammer
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Patent number: 8287934Abstract: The invention relates to the use of 5-acetyl-2,5-dimethyl-2-hydroxy-tetrahydrofuran-3-one (diacetyl dimer of formula (I)) in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two, three or four of its stereoisomers (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor; and/or (iii) as an aromatic and/or flavoring substance.Type: GrantFiled: May 7, 2007Date of Patent: October 16, 2012Assignee: Symrise AGInventors: Jakob Ley, Berthold Weber, Gerhard Krammer, Ingo Reiss, Heinz-Jürgen Bertram, Ian Gatfield, Petra Hoffmann-Lücke
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Patent number: 7919133Abstract: The present invention relates to the use of a compound of formula (I) or a mixture of compounds of formula (I) wherein: R1, R2, and R3 are independently H or an alkyl group having 1 to 3 C-atom, wherein at least one of R1, R2, and R3 is not H; R4 is H, an alkyl group having 1 to 6 C-atom, or an alkenyl group having 2 to 6 C-atom; R5, R6, R7, and R8 are independently H or methyl; and R9 is H, an alkyl group having 5 to 12 C-atoms, or an alkenyl group having 5 to 12 C-atoms; as a flavoring substance or mixture of flavoring substances.Type: GrantFiled: May 8, 2008Date of Patent: April 5, 2011Assignee: SYMRISE GmbH & Co. KGInventors: Jan Looft, Tobias Vössing, Jakob Ley, Michael Backes, Maria Blings
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Publication number: 20100331349Abstract: The use of ?-aminobutyric acid or a physiologically acceptable salt of ?-aminobutyric acid to mask or reduce the unpleasant flavour impression of an unpleasantly tasting substance is described. The food, beverage or oral care preparations or oral pharmaceutical preparations comprising at least one unpleasantly tasting substance and ?-aminobutyric acid are also described.Type: ApplicationFiled: March 29, 2005Publication date: December 30, 2010Inventors: Jakob Ley, Gunter Kindel, Gerhard Krammer, Thomas Hofmann, Nina Rotzoll
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Publication number: 20100233102Abstract: The invention provides the use of a 4-hydroxydihydrochalcone of the formula (I) wherein R1, R2, R3 and R4 each, independently, represent H, OH or O-alkyl, with the proviso that at least one of the groups R1, R2 or R3 represents OH, a salt of such a 4-hydroxydihydrochalcone of the formula (I), a mixture containing or consisting of two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above, a mixture containing or consisting of salts of two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above or a mixture containing or consisting of a 4-hydroxydihydrochalcone of the formula (I) or two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above, and a salt of a 4-hydroxydihydrochalcone of the formula (I) or two or more salts of different 4-hydroxydihydrochalcones of the formulaType: ApplicationFiled: March 21, 2007Publication date: September 16, 2010Applicant: SYMRISE GmbH & Co. KGInventors: Gerhard Krammer, Jakob Ley, Thomas Riess, Martin Haug, Susanne Paetz, Günter Kindel, Ralph Schmidtmann
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Publication number: 20100062030Abstract: The invention relates to the use of 5-acetyl-2,5-dimethyl-2-hydroxy-tetrahydrofuran-3-one (diacetyl dimer of formula (I)) in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two, three or four of its stereoisomers (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavour; and/or (iii) as an aromatic and/or flavouring substance.Type: ApplicationFiled: May 7, 2007Publication date: March 11, 2010Applicant: SYMRISE GmbH & Co., KGInventors: Jakob Ley, Berthold Weber, Gerhard Krammer, Ingo Reiss, Heinz-Jürgen Bertram, Ian Galfield, Petra Hoffmann-Lücke
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Publication number: 20090214728Abstract: The present invention relates to a mixture comprising or consisting of: (a) one or more inorganic salts which are suitable for nutrition and are not sodium chloride, (b) one or more mono- or polyvalent salts of polybasic food acids, (c) one or more amino acids, or salts thereof, which are suitable for nutrition.Type: ApplicationFiled: October 6, 2006Publication date: August 27, 2009Applicant: SYMRISE GmbH & Co. KGInventors: Jakob Ley, Guenter Kindel, Sylvia Muche, Kathrin Freiherr, Stefan Brennecke, Gerhard Krammer
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Publication number: 20090208426Abstract: The invention relates to the use of 2,5-diacetyl-3a,5,6,6a-tetrahydro-6a-hydroxy-2,3a,5-trimethylfuro[2,3-d]-1,3-dioxole (diacetyl trimer) of the formula in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two or more of the stereoisomers (i) as an odoriferous or aromatic substance, (ii) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (iii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavour, and/or (iv) for masking a bitter flavour. The invention furthermore relates to corresponding aromatic compositions as well as compositions which serve for nutrition, oral hygiene, consumption for pleasure or for oral pharmaceutical use.Type: ApplicationFiled: November 30, 2005Publication date: August 20, 2009Applicant: SYMRISE GMBH & CO. KGInventors: Ian Gatfield, Jakob Ley, Ingo Reiss, Günter Kindel, Gerhard Krammer
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Publication number: 20090124701Abstract: An individual alkamide and/or a mixture having two or more different alkamides, is disclosed for changing, masking or reducing the unpleasant flavor impression of an unpleasant-tasting substance or mixture of substances. The alkamide can be trans-pellitorine; cis-pellitorine; 2Z,4Z- or 2Z,4E-decadienoic acid-N-isobutylamide; 2E,4E-decadienoic acid-N-([2S]-2-methylbutyl)amide; 2E,4E-decadienoic acid-N-([2R]-2-methylbutylamide); 2E,4Z-decadienoic acid-N-(2-methylbutyl)amide; achilleamide; sarmentine; 2E- or 3E-decenoic acid-N-isobutylamide; 3E-nonenoic acid-N-isobutylamide; spilanthol; homospilanthol; 2E,6Z,8E-decatrienoic acid-N-([2R]-2-methylbutyl)amide; 2E- or 2Z-decen-4-oic acid-N-isobutylamide; ?-sanshool; ?-hydroxysanshool; ?-hydroxysanshool; ?-hydroxysanshool; ?-hydroxyisosanshool; ?-dehydrosanshool; ?-sanshool; bungeanool; isobungeanool; dihydrobungeanool; or tetrahydrobungeanool, or combinations thereof.Type: ApplicationFiled: November 6, 2008Publication date: May 14, 2009Applicant: SYMRISE GmbH & Co. KGInventors: Kathrin Langer, Jakob Ley, Gerald Reinders, Gunter Kindel, Gerhard Krammer