Patents by Inventor Jakob Ley

Jakob Ley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090028804
    Abstract: The invention relates to a method for finding and assessing agonists [and] antagonists of the aryl hydrocarbon receptor (Ah receptor; AhR), to the agonists and antagonists themselves and to uses thereof.
    Type: Application
    Filed: November 28, 2006
    Publication date: January 29, 2009
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jean Krutmann, Martina Herrmann, Gabriele Vielhaber, Jakob Ley, Oskar Koch
  • Patent number: 7482479
    Abstract: The invention describes a process for the production of 2E,4Z-decadienoic acid-N-isobutylamide (cis-pellitorine) and its use as a pungent principle and aromatic substance having a heat-generating effect, preferably in preparations used for foodstuffs, oral hygiene or luxury foodstuffs.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: January 27, 2009
    Assignee: Symrise GmbH & Co., KG
    Inventors: Ian-Lucas Gatfield, Jakob Ley, Jan Foerstner, Gerhard Krammer, Arnold Machinek
  • Publication number: 20080317923
    Abstract: The invention relates to an aroma composition for reducing or suppressing a bitter, astringent impression in the oral cavity, comprising (i) one or more salivatory aroma substances and/or flavorings and (ii) one or more particular bitterness-masking aroma substances and/or flavorings and optionally (iii) one or more further aroma substances, wherein preferably at least one aroma substance is an aroma substance which suppresses malodors and optionally (iv) one or more auxiliary substances or carriers.
    Type: Application
    Filed: June 19, 2008
    Publication date: December 25, 2008
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jakob Ley, Kathrin Langer, Gerhard Krammer, Gerald Reinders, Gunter Kindel, Christian Nolte
  • Publication number: 20080305052
    Abstract: The use of hesperetin of formula (I) is described wherein the hesperetin of formula (I) is in the form of a (2S)-enantiomer, (2R)-enantiomer or any desired mixture of the two enantiomers, a salt of hesperetin of formula (I), —a mixture comprising or consisting of two or more salts of the hesperetin of formula (I), or a mixture comprising or consisting of hesperetin of formula (I) and one or more salts of hesperetin of formula (I) for enhancing the sweet taste of a sweet-tasting substance or sweet olfactory impression of a flavouring which gives a sweet olfactory impression.
    Type: Application
    Filed: July 25, 2006
    Publication date: December 11, 2008
    Applicant: SYMRISE GmbH & Co. KG.
    Inventors: Jakob Ley, Guenter Kindel, Susanne Paetz, Thomas Riess, Martin Haug, Ralph Schmidtmann, Gerhard Krammer
  • Publication number: 20080292763
    Abstract: The present invention relates to the use of a compound of formula (I) or a mixture of compounds of formula (I) wherein: R1, R2, and R3 are independently H or an alkyl group having 1 to 3 C-atom, wherein at least one of R1, R2, and R3 is not H; R4 is H, an alkyl group having 1 to 6 C-atom, or an alkenyl group having 2 to 6 C-atom; R5, R6, R7, and R8 are independently H or methyl; and R9 is H, an alkyl group having 5 to 12 C-atoms, or an alkenyl group having 5 to 12 C-atoms; as a flavoring substance or mixture of flavoring substances.
    Type: Application
    Filed: May 8, 2008
    Publication date: November 27, 2008
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jan Looft, Tobias Vossing, Jakob Ley, Michael Backes, Maria Blings
  • Publication number: 20080242740
    Abstract: The invention primarily relates to aroma compositions of (i) certain saliva-stimulating alkamides having a tingling, pungent and/or hot flavor (such as for example pellitorines, spilanthol) with (ii) hesperetin (5,7-dihydroxy-3-(3-hydroxy-4-methoxyphenyl)-chroman-4-one) or the enantiomers and/or salts thereof and/or (iii) 4-hydroxydihydrochalcones (3-(4-hydroxyphenyl)-1-phenylpropan-1-ones) and/or the salts thereof, the use thereof to enhance the sweet flavor of sweet-tasting substances or the sweet odor impression of aroma substances which give rise to a sweet odor impression, but in particular to enhance the sweet initial flavor or odor (initial sweetness). The invention thus relates to the use of said aroma compositions as general sweetness enhancers and enhancers of initial sweetness.
    Type: Application
    Filed: March 28, 2008
    Publication date: October 2, 2008
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jakob Ley, Kathrin Freiherr, Gerhard Krammer, Gerald Reinders
  • Publication number: 20080242585
    Abstract: The use (i) of a compound of formula 2 wherein R3 and R4 independently of one another represent a C2-C4-alkyl or -alkenyl radical or (ii) of a mixture consisting of or comprising: at least one such compound of formula 2 as well as at least one compound of formula 1 and/or at least one compound of formula 3, wherein R1, R2, R3, R4, R5 and R6 independently of one another represent a C2-C4-alkyl or -alkenyl radical, as a fragrance or flavouring is described.
    Type: Application
    Filed: September 9, 2005
    Publication date: October 2, 2008
    Applicant: SYMRISE GMBH & CO. KG
    Inventors: Frank Ott, Gunter Kindel, Jakob Ley, Gehard Krammer, Claus-Oliver Schmidt, Peter Schieberle, Michael Granvogl
  • Publication number: 20080227866
    Abstract: The use of a hydroxyphenylalkadione derivative of the formula (I) wherein, for X, a and Y: X is a —CH2—, —NH— or —O— group, Y is a —CH2— group and a is a single bond or X and Y are in each case a —CH— group and a is a double bond in the Z or E configuration, wherein, for R1, R2 and R3 R1 denotes hydrogen, an aliphatic radical having 1 to 4 C atoms or a —O—R5, —S—R5 or —NR5R6 group and R2 and R3 independently of one another denote hydrogen or an alkyl having 1, 2, 3, 4 or 5 C atoms which is optionally substituted by one or more oxo groups or R7—O— groups or R1 and R2 together form an aliphatic ring which contains a total of 4 to 10 carbon atoms and 0 or 1 oxygen atom, wherein the ring constituent represented by R1 and R2 is optionally substituted by one or more oxo groups and/or R7—O— groups and/or aliphatic radicals having 1 to 4 C atoms and R3 denotes hydrogen or an alkyl having 1, 2, 3, 4 or 5 C atoms which is optionally substituted by one or more oxo groups or R7—O— groups or R2 and
    Type: Application
    Filed: June 27, 2006
    Publication date: September 18, 2008
    Applicant: SYMRISE GMBH & CO. KG
    Inventors: Jakob Ley, Heinz-Jurgen Bertram, Gerhard E. Krammer, Gunter Kindel
  • Publication number: 20080227867
    Abstract: The use is described of the 4-hydroxychalcone derivatives of the formula (I) wherein A may represent a single or double bond, R1, R2 and R3, mutually independently, may in each case mean H, OH or (preferably C1-C4) alkoxy, providing that at least one of the residues R1 to R3 means OH, and R4 means H, OH or (preferably C1-C4) alkoxy, and/or (ii) the salts thereof and (iii) mixtures thereof to mask or reduce the unpleasant taste impression of an unpleasant tasting substance, as are corresponding methods and preparations.
    Type: Application
    Filed: March 12, 2008
    Publication date: September 18, 2008
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jakob Ley, Susanne Paetz, Thomas Riess, Gerhard Krammer
  • Publication number: 20080220140
    Abstract: The invention relates to the use of a propenylphenyl glycoside of formula (I) wherein R is (1E)-prop-1-enyl, (1Z)-prop-1-enyl or prop-2-enyl; and Glc is an ?- or ?-glycosidically bonded mono- or oligo-saccharide, for enhancing the sweet taste of a sweet-tasting substance or the sweet odour impression of a flavouring that produces a sweet odour impression.
    Type: Application
    Filed: January 25, 2008
    Publication date: September 11, 2008
    Applicant: SYMRISE GmbH & Co. KG
    Inventors: Jakob Ley, Jan Looft, Susanne Paetz
  • Publication number: 20080214675
    Abstract: The use is described of hydroxybenzoic acid amides having formula (I) wherein R1 to R5 mutually independently denote hydrogen, hydroxy, methoxy or ethoxy, with the proviso that at least one of the radicals R1 to R5 denotes hydroxy. and R6 denotes hydrogen, methyl or ethyl and n denotes 1 or 2, their salts and mixtures thereof, to mask or reduce the unpleasant flavour impression of an unpleasantly tasting substance and/or to strengthen the sweet flavour impression of a sweet substance.
    Type: Application
    Filed: August 2, 2005
    Publication date: September 4, 2008
    Applicant: SYMRISE GMBH & CO. KG
    Inventors: Jakob Ley, Heinz-Jurgen Bertram, Gunter Kindel, Gerhard Krammer
  • Publication number: 20080113073
    Abstract: The use of hydroxydeoxybenzoins of formula (I) wherein R1 and R2 independently of one another represent hydrogen or lower alkyl and R3, R4, R5 and R6 independently of one another represent hydrogen, hydroxy or lower alkoxy, salts thereof and mixtures thereof to mask or reduce the unpleasant taste impression of a substance that tastes unpleasant and/or to enhance the sweet taste of a substance that tastes sweet.
    Type: Application
    Filed: March 9, 2006
    Publication date: May 15, 2008
    Applicant: SYMRISE GMBH & CO. KG
    Inventors: Jakob Ley, Gunter Kindel, Susanne Paetz, Gerhard G.E. Krammer
  • Publication number: 20080096969
    Abstract: The present invention relates to specific N?-(menthanecarbonyl)amino acid amides of the formula (I): and mixtures thereof and to the use of the specific N?-(menthanecarbonyl)amino acid amides and mixtures thereof as physiological cooling active ingredients.
    Type: Application
    Filed: October 17, 2007
    Publication date: April 24, 2008
    Applicant: SYMRISE GMBH & CO. KG
    Inventor: Jakob LEY
  • Publication number: 20080076699
    Abstract: The use is described of (i) a fatty acid ester having formula (I) or (ii) a mixture of two or more different fatty acid esters having formula (I) wherein R1 is an alkyl radical having 1 to 10 C atoms, a cycloalkyl radical having 3 to 8 C atoms, an alkenyl radical having 2 to 10 C atoms or a cycloalkenyl radical having 3 to 8 C atoms, R2 is an alkyl radical having 1 to 10 C atoms, n denotes 1, 2, 3, 4 or 5, and the two double bonds in the fatty acid radical are mutually independently (E)- or (Z)-configured, as a fragrance and/or aroma substance.
    Type: Application
    Filed: September 20, 2007
    Publication date: March 27, 2008
    Applicant: SYMRISE GMBH & CO. KG
    Inventors: Jakob LEY, Thomas RIESS
  • Publication number: 20070202188
    Abstract: The use of an alkenecarboxylic acid N-alkylamide of the formula or of a mixture of two or more compounds of the formula (3a) and/or (3b), wherein, in each case R1 represents an alkyl radical and R2 represents a lower alkyl radical, as (i) a piquant substance and/or (ii) for generating a sensation of heat on consumption and/or (iii) for intensifying the flavour of ethanol and/or (iv) for imitating the flavour of ethanol, is described.
    Type: Application
    Filed: October 28, 2004
    Publication date: August 30, 2007
    Inventors: Jakob Ley, Gunter Kindel, Gerhard Krammer
  • Publication number: 20050234132
    Abstract: The invention describes a process for the production of 2E,4Z-decadienoic acid-N-isobutylamide (cis-pellitorine) and its use as a pungent principle and aromatic substance having a heat-generating effect, preferably in preparations used for foodstuffs, oral hygiene or luxury foodstuffs.
    Type: Application
    Filed: June 20, 2003
    Publication date: October 20, 2005
    Inventors: Ian-Lucas Gatfield, Jakob Ley, Jan Foerstner, Gerhard Krammer, Arnold Machinek
  • Publication number: 20050208084
    Abstract: The present invention describes various mandelic acid alkylamides and their use as pungent compounds and flavour compounds with a heat-generating effect, preferably in preparations for use in nutrition, oral hygiene or consumed for pleasure.
    Type: Application
    Filed: June 14, 2003
    Publication date: September 22, 2005
    Inventors: Jakob Ley, Gerhard Krammer, Arnold Machinek
  • Patent number: 6117365
    Abstract: The invention relates to specific phenolic acid amides of hydroxy-substituted benzylamines of the formula I ##STR1## to a process for their preparation and to their use as antioxidants or as free-radical scavengers, in particular in the cosmetic or dermatological field, in foods and cosmetic and dermatological compositions comprising these phenolic acid amides.
    Type: Grant
    Filed: August 27, 1998
    Date of Patent: September 12, 2000
    Assignee: Haarmann & Reimer GmbH
    Inventor: Jakob Ley
  • Patent number: 6039939
    Abstract: N-Acyl-hydroxyamino acid alkyl esters help to strengthen the natural barrier function of the skin against environmental influences and external irritation. They improve the suppleness and the elasticity of skin and hair, help to increase the moisture content and protect skin and hair from drying out.
    Type: Grant
    Filed: March 13, 1998
    Date of Patent: March 21, 2000
    Assignee: Haarmann & Reimer GmbH
    Inventors: Jakob Ley, Roland Langner