Abstract: Various methods and systems for blood pressure monitoring are provided. A device for monitoring blood pressure may include a memory storing instructions for receiving one or more signals representative of one or more patient parameters, wherein at least one of the one or more signals comprises a plethysmography signal. The memory also stores instructions for determining a change in a pulse shape metric of the plethysmography signal and determining a change in a blood pressure signal over a period of time based on the one or more signals. The memory also stores instructions for determining a confidence level of the blood pressure signal based at least in part on a correlation between the change in the blood pressure signal and the change in the pulse shape metric over the period of time. The device also includes a processor configured to execute the instructions.

Abstract: A model predicts the geometry of both visible and occluded traversable surfaces from input images. The model may be trained from stereo video sequences, using camera poses, per-frame depth, and semantic segmentation to form training data, which is used to supervise an image to image network. In various embodiments, the model is applied to a single RGB image depicting a scene to produce information describing traversable space of the scene that includes occluded traversable. The information describing traversable space can include a segmentation mask of traversable space (both visible and occluded) and non-traversable space and a depth map indicating an estimated depth to traversable surfaces corresponding to each pixel determined to correspond to traversable space.

Abstract: Antibodies that bind to the circumsporozoite protein (CSP) of Plasmodium falciparum. Use of such antibodies as anti-malarial agents, to confer protection against infection by malarial parasites such as P. falciparum by insect vector transmission. Diagnosis of malaria using anti-CSP antibodies. Methods of determining efficacy of candidate vaccine compositions in development and testing of anti-malarial vaccines.

Abstract: A method for training a depth estimation model with depth hints is disclosed. For each image pair: for a first image, a depth prediction is determined by the depth estimation model and a depth hint is obtained; the second image is projected onto the first image once to generate a synthetic frame based on the depth prediction and again to generate a hinted synthetic frame based on the depth hint; a primary loss is calculated with the synthetic frame; a hinted loss is calculated with the hinted synthetic frame; and an overall loss is calculated for the image pair based on a per-pixel determination of whether the primary loss or the hinted loss is smaller, wherein if the hinted loss is smaller than the primary loss, then the overall loss includes the primary loss and a supervised depth loss between depth prediction and depth hint. The depth estimation model is trained by minimizing the overall losses for the image pairs.

Abstract: A method for training a depth estimation model with depth hints is disclosed. For each image pair: for a first image, a depth prediction is determined by the depth estimation model and a depth hint is obtained; the second image is projected onto the first image once to generate a synthetic frame based on the depth prediction and again to generate a hinted synthetic frame based on the depth hint; a primary loss is calculated with the synthetic frame; a hinted loss is calculated with the hinted synthetic frame; and an overall loss is calculated for the image pair based on a per-pixel determination of whether the primary loss or the hinted loss is smaller, wherein if the hinted loss is smaller than the primary loss, then the overall loss includes the primary loss and a supervised depth loss between depth prediction and depth hint. The depth estimation model is trained by minimizing the overall losses for the image pairs.

Abstract: An energy absorbing strut having, a first end coupled with an inner cylinder, and a second end connected with a hollow rod extending within the inner cylinder. A piston is carried by the rod having an outer surface sealing against an inside diameter of the inner cylinder and forming a compression chamber and a rebound chamber bounded by the piston, the rod having an internal passageway communicating between the compression chamber and the rebound chamber. An inertial mass carried by the rod movable axially on the rod between a closed position against and annular rod passageway and an open position opening the rod passageway and allowing the flow of a hydraulic fluid between the compression chamber and the rebound chamber. A spring acts on the inertial mass biasing the inertial mass toward the closed position. The energy absorbing strut may be used in a blast mitigation system for a military vehicle or other applications for providing shock isolation between two structures.

Abstract: A method for training a depth estimation model with depth hints is disclosed. For each image pair: for a first image, a depth prediction is determined by the depth estimation model and a depth hint is obtained; the second image is projected onto the first image once to generate a synthetic frame based on the depth prediction and again to generate a hinted synthetic frame based on the depth hint; a primary loss is calculated with the synthetic frame; a hinted loss is calculated with the hinted synthetic frame; and an overall loss is calculated for the image pair based on a per-pixel determination of whether the primary loss or the hinted loss is smaller, wherein if the hinted loss is smaller than the primary loss, then the overall loss includes the primary loss and a supervised depth loss between depth prediction and depth hint. The depth estimation model is trained by minimizing the overall losses for the image pairs.

Abstract: A needle access assembly and method for obtaining percutaneous needle access with little or no fluoroscopy is disclosed. The method includes selecting a target for percutaneous access, directing a laser guide at a desired needle-insertion angle and in line with the selected target, aligning the needle access assembly with the laser, and inserting the needle into the target.

Abstract: Provided herein are methods for aligning raw genetic sequence data generated by a sequencing device. Also provided herein are methods and systems for quantifying the probability that possible alignments for one or more read pairs are correct, for calling known variants, and for detecting novel structural variants.

Abstract: The present invention relates to one-piece fasteners having a strap and a locking head utilized to secure elongate objects such as cables in a bundle, and in particular, to hybrid fasteners having both raised detents and locking teeth as part of the fastener strap.

Abstract: A method for validating data changes made to a database is disclosed. The changes are made in the context of a transaction, and validation is performed using a rules database storing a plurality of rules. The method includes identifying a set of data entities affected by one or more data changes made in the context of the transaction. In response to an instruction to commit the transaction, data entities in the set of affected data entities are validated using rules from the rules database. The transaction is committed in dependence on the outcome of the validation.

Abstract: Various methods and systems for blood pressure monitoring are provided. A device for monitoring blood pressure may include a memory storing instructions for receiving one or more signals representative of one or more patient parameters, wherein at least one of the one or more signals comprises a plethysmography signal. The memory also stores instructions for determining a change in a pulse shape metric of the plethysmography signal and determining a change in a blood pressure signal over a period of time based on the one or more signals. The memory also stores instructions for determining a confidence level of the blood pressure signal based at least in part on a correlation between the change in the blood pressure signal and the change in the pulse shape metric over the period of time. The device also includes a processor configured to execute the instructions.

Abstract: A high frequency high power converter system comprises: a plurality of resonant tank circuits arranged in parallel, a plurality of transformers, each transformer having a single primary winding and a plurality of secondary windings, and a vacuum electronic device, the output of each resonant tank circuit being applied to a respective different transformer and the outputs of the transformers being arranged to drive the vacuum electronic device.

Abstract: Various methods and systems for blood pressure monitoring are provided. A device for monitoring blood pressure may include a memory storing instructions for receiving one or more signals representative of one or more patient parameters, wherein at least one of the one or more signals comprises a plethysmography signal. The memory also stores instructions for determining a change in a pulse shape metric of the plethysmography signal and determining a change in a blood pressure signal over a period of time based on the one or more signals. The memory also stores instructions for determining a confidence level of the blood pressure signal based at least in part on a correlation between the change in the blood pressure signal and the change in the pulse shape metric over the period of time. The device also includes a processor configured to execute the instructions.

Abstract: Embodiments are directed to obtaining data based on samples of a vibration signal, processing, by at least one processor, the data to obtain a qualitative and quantitative assessment of a health of the one or more components based on an application of the data to at least one model, and outputting the assessment. Embodiments of the disclosure may be applied to one or more components of a drive shaft of an aircraft.

Abstract: Antibodies that bind to the circumsporozoite protein (CSP) of Plasmodium falciparum. Use of such antibodies as anti-malarial agents, to confer protection against infection by malarial parasites such as P. falciparum by insect vector transmission. Diagnosis of malaria using anti-CSP antibodies. Methods of determining efficacy of candidate vaccine compositions in development and testing of anti-malarial vaccines.

Abstract: The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.

Abstract: The present invention relates to one-piece fasteners having a strap and a locking head utilized to secure elongate objects such as cables in a bundle, and in particular, to hybrid fasteners having both raised detents and locking teeth as part of the fastener strap.

Abstract: The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.

Abstract: A wafer container utilizes a rigid polymer tubular tower with slots and a “getter” therein for absorbing and filtering moisture and vapors within the wafer container. The tower preferably utilizes a purge grommet at the base of the container and may have a check valve therein to control the flow direction of gas (including air) into and out of the container and with respect to the tower. The tower is sealingly connected with the grommet. The tower may have a getter media piece rolled in an elongate circular fashion forming or shaped as a tube and disposed within the tower and may have axially extending. The media can provide active and/or passive filtration as well as having capabilities to be recharged. Front opening wafer containers for 300 mm sized wafers generally have a pair of recesses on each of the left and right side in the inside rear of the container portions.