Abstract: An integrated circuit die stack and method thereof are described herein that is capable of detecting a physical tampering event. The integrated circuit die stack includes a first integrated circuit die including a sensor network that extends substantially across an entire top surface of the first integrated circuit die, and a second integrated circuit die stacked below the first integrated circuit die. The second integrated circuit die is configured to receive sensing signals generated by the sensor network via a plurality of through-silicon-vias coupled with the first integrated circuit die and the second integrated circuit die.

Abstract: Systems and methods are provided for integrated healthcare management. The systems and methods include establishing a medical record data, accessing information about a treatment related to the medical record data, obtaining biometric data related to the treatment, processing the biometric data, determining whether the treatment is appropriate with respect to the biometric data, in response to the treatment being appropriate with respect to the biometric data, administering medication, and in response the treatment not being appropriate with respect to the biometric data, determining a new treatment, and administering new medication based on the new treatment.

Abstract: A method of using a sterilization wrap system including a permeable material having barrier properties and having a first surface and a second opposing surface, the exterior panel being substantially opaque or having a first level of translucence, and an interior panel including a permeable material having barrier properties and having a first surface and a second opposing surface, the interior panel having a level of translucence that is higher than the translucence of the exterior panel, the panels being joined together over at least a portion of their surfaces. Also disclosed is inspection of the sterilization wrap system for exterior panel breaches by looking for light passing through a panel facing the viewer.

Abstract: An improvement to a system for identity verification is provided in which data records are continuously updates to provide the validation, verification and trusted confidence values of an entity (an individual person or organization) for each type and level of identification needed. In addition to the iterative updating of conventional data, the historical change in recorded data is compared with newly received entity identification verification parameters, with changes and an analysis of the changes also iteratively tracked and stored as part of the data record with continuous updating. The data record may also include emotional, mood or feelings responses to emotional, mood or feeling prompts. Similarly, the historical change in emotional, mood or feeling responses is compared with newly received responses to similar or different prompts, with changes and an analysis of the changes also iteratively tracked and stored as part of the data record with continuous updating.

Abstract: An inclination guide for use with an implant insertion tool during a surgical procedure includes a unitary body having a clip configured to be coupled to a mounting surface of the implant insertion tool, an elongated riser extending from the clip, and an elongated indicator extending from the elongated riser to a distal end. Such a design allows for an inexpensive and lightweight inclination guide that may be easily and quickly adjusted after assembly.

Abstract: A surgical rotational tool driver and method. The driver includes a driveline extending within a hollow shaft and a head part including connection features for connecting to a connection member of a surgical rotational tool. The connection features of the head part include a housing and a pair of jaw member each including jaws for receiving the connection member. Each jaw member is pivotally mounted for rotation between: a first position for receipt of the connection member and a second position for retaining the connection member. The connection features of the head part further include a locking mechanism including a pair of catches for engaging with a respective catch of each jaw member to lock the jaw members in the second position. The locking mechanism also includes a release member slideably moveable within the housing to release the catches of the locking mechanism from the catches of the jaw members.

Abstract: This disclosure is directed to techniques for detecting and mitigating inaccurate sensing in a medical system. In some examples, one or more sensors of the medical system may include at least one electrode configured to sense an impedance of a portion of a patient's body proximate to the electrode and processing circuitry of the medical system may detect an inaccuracy in the data corresponding to the one or more patient physiological parameters based upon data including at least the sensed impedance of the portion of the patient body; correct at least a portion of the inaccuracy in the data corresponding to the one or more patient physiological parameters; and generate, for display on a display device, output data indicating the inaccuracy in the data corresponding to the one or more patient physiological parameters.

Abstract: In a method of controlling a hydraulic actuator of a test station, a differential signal is generated based on a difference between a reference signal and a feedback signal using an actuator controller. A flow rate control circuit is set in one of a first state and a second state based on a flow rate attenuation signal. The differential signal is delivered to the control valve as an actuator command signal when the flow rate control circuit is in the first state. An attenuated differential signal is delivered to the control valve as the actuator command signal when the flow rate control circuit is in the second state. A flow rate and a direction of the hydraulic fluid flow is controlled based on the actuator command signal. The flow rate corresponding to the attenuated differential signal is less than the flow rate corresponding to the differential signal.

Abstract: A coupler for securing an attachment to an earth working machine. The coupler comprises a coupler body that presents a receptacle having a capture region. A pin of an attachment can move into and out of the capture region. A retainer can capture the pin in the capture region but the retainer can be moved by a hydraulically driven driver to a position to allow release the pin from the capture region. A trigger that the pin will strike when the pin moves into or out of the capture region, decouples the driver from the retainer and the retainer is then allowed to be biased back to its retaining position by a spring.

Abstract: Described herein are methods of treating cancer in a subject in need thereof comprising administering to the subject a pharmaceutical composition comprising 1-(4-(benzylamino)-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide, or a pharmaceutically acceptable salt thereof, whereby the subject experiences a therapeutic response.

Abstract: The present application is directed to immunomodulatory compositions comprising invariant NKT cell (iNKT cell) agonist compounds that induce expansion of tissue resident memory T-cells (Trm Cells) in combination with an immune stimulator agent that enhances an immune response to a target antigen or a polynucleotide encoding the immune stimulator. The iNKT agonists are ?-GalCer analogue compounds modified at the 6 position of the galactose ring. The immune stimulator is an antigen or an mRNA encoding an antigen to create a vaccine formulation. These combinations are used in the treatment of infection or cancer in a subject, or to enrich the number of Trm cells in the liver of a subject.

Abstract: A tire inflation valve having anti-rotation features has an external valve seat, and includes a valve body, a valve stem extending through the length of the valve body, and anti-rotation features disposed interior to the valve body. The valve stem is configured to move relative to the valve body, such that a resilient seating surface disposed at a proximal end of the valve stem is displaced relative to a valve seat formed by an exterior surface of a proximal end of the valve body. The anti-rotation features may include a complementary slot and protrusion, a keyway and complementary protruding ridge, and/or complementary channels and lateral protrusions.