Abstract: An actuator component for a droplet ejection head; wherein said actuator component comprises a substrate and one or more strips of piezoelectric material fixedly attached to said substrate; wherein said one or more strips of piezoelectric material comprise one or more layers of piezoelectric material, and an array of fluid chambers defined within said one or more strips of piezoelectric material and extending in an array direction; wherein said actuator component further comprises one or more cover parts; wherein the or each cover part extends in said array direction and is fixedly attached to at least one of a side face of one of said strips of piezoelectric material and/or at least a portion of said substrate; and wherein said one or more cover parts comprise a plurality of openings so as to enable fluid to be supplied to selected ones of said fluid chambers through said openings. Associated methods of manufacturing an actuator component for a droplet ejection head are also provided.

Abstract: An actuator component for a droplet ejection head; wherein said actuator component comprises a substrate and one or more strips of piezoelectric material fixedly attached to said substrate; wherein said one or more strips of piezoelectric material comprise one or more layers of piezoelectric material, and an array of fluid chambers defined within said one or more strips of piezoelectric material and extending in an array direction; wherein said actuator component further comprises one or more cover parts; wherein the or each cover part extends in said array direction and is fixedly attached to at least one of a side face of one of said strips of piezoelectric material and/or at least a portion of said substrate; and wherein said one or more cover parts comprise a plurality of openings so as to enable fluid to be supplied to selected ones of said fluid chambers through said openings. Associated methods of manufacturing an actuator component for a droplet ejection head are also provided.

Abstract: A machine and method of reducing duplicate transmission data employs one more more digests to track field/value pairs that have previously been distributed. Each digest contains a record table and a segment table. The record table includes anonymous identifier records, each of which contain an anonymous identifier and one or more indexes into the segment table. The segment table comprises an array of every existing data field/value pair. Before distribution of update data, each record is matched to an anonymous identifier record in the record table. The segment values in the prospective distribution record are compared to the digest's anonymous identifier record, used to determine which data has already been distributed, and thus will be suppressed in the distribution.

Abstract: A machine and method of reducing duplicate transmission data employs one more more digests to track field/value pairs that have previously been distributed. Each digest contains a record table and a segment table. The record table includes anonymous identifier records, each of which contain an anonymous identifier and one or more indexes into the segment table. The segment table comprises an array of every existing data field/value pair. Before distribution of update data, each record is matched to an anonymous identifier record in the record table. The segment values in the prospective distribution record are compared to the digest's anonymous identifier record, used to determine which data has already been distributed, and thus will be suppressed in the distribution.

Abstract: A railroad switching apparatus utilizing a tie which is positioned under rails and points used in switching railroad cars. A support is interposed the tie and the rails and points and includes a passageway to guide the first and second indicator bars which are attached to the points. A slider is also employed at the attachment point of the indicator bars to the points to accommodate the thermal expansion and contraction of the rails and points. The indicator bars are formed into a coaxial unit in order to allow simple observation of the relative movement between the first and second indicator bars to determine proper movement of the points relative to the rails.

Abstract: A railroad switching apparatus utilizing a tie which is positioned under rails and points used in switching railroad cars. A support is interposed the tie and the rails and points and includes a passageway to guide the first and second indicator bars which are attached to the points. A slider is also employed at the attachment point of the indicator bars to the points to accommodate the thermal expansion and contraction of the rails and points. The indicator bars are formed into a coaxial unit in order to allow simple observation of the relative movement between the first and second indicator bars to determine proper movement of the points relative to the rails.

Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.

Abstract: A railroad switching apparatus utilizing a tie which is positioned under rails and points used in switching railroad cars. A support is interposed the tie and the rails and points and includes a passageway to guide the first and second indicator bars which are attached to the points. A slider is also employed at the attachment point of the indicator bars to the points to accommodate the thermal expansion and contraction of the rails and points. The indicator bars are formed into a coaxial unit in order to allow simple observation of the relative movement between the first and second indicator bars to determine proper movement of the points relative to the rails.

Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.

Abstract: A shield device for a switch point adjusting element used in combination with a railroad switch. The device includes first and second shells that mate with one another to form a cover having an inner chamber. The inner chamber is sized to loosely enclose the adjusting element. At least one boss having a recessed generally aligns with a guide having a passageway on the cover. A fastener extends at least partially through the passageway to the guide and engages the recess of the boss to hold the first and second shells together.

Abstract: A railroad switching apparatus utilizing a tie which is positioned under rails and points used in switching railroad cars. A support is interposed the tie and the rails and points and includes a passageway to guide the first and second indicator bars which are attached to the points. A slider is also employed at the attachment point of the indicator bars to the points to accommodate the thermal expansion and contraction of the rails and points. The indicator bars are formed into a coaxial unit in order to allow simple observation of the relative movement between the first and second indicator bars to determine proper movement of the points relative to the rails.

Abstract: Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile.

Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.

Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.

Abstract: The present invention provides novel biomarkers for use in the diagnosis and prognosis of cancerous and malignant conditions and further of diseases which are mediated by a proinflammatory immune response. The biomarkers are glycoproteins, the levels of expression of which have been correlated by the inventors to correspond to particular disease conditions. The invention further extends to methods for use in monitoring the response to therapy of a treatment for use in the treatment of a cancerous condition or proinflammatory disease.

Abstract: This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

Abstract: This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

Abstract: Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile.

Abstract: Systems and methods for automated analysis and targeting of digital media based upon spoken topic or criterion recognition of the digital media are provided. Pre-specified criteria are used as the starting point for a top-down topic or criterion recognition approach. Individual words used in the audio track of the digital media are recognized only in context of each candidate topic or criterion hypothesis, thus yielding greater accuracy than two-step approaches that first transcribe speech and then recognize topic based upon the transcription.

Abstract: This invention relates to novel compounds having the structural formula Ia or formula Ib: Ia Ib and their pharmaceutically acceptable salts, tautomers or in vivo hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of A? related pathologies such as cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.