Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure is related to improving image quality in a scanning camera system via scan angle selection to obtain images having overlap for performing image stitching, dynamically tuning an aperture of a camera in the scanning camera system, updating pixel values of an image using vignetting data, or a combination thereof.

Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: This disclosure is related to positioning one or more glass plates between an image sensor and lens of a camera in a scanning camera system; determining plate rotation rates and plate rotation angles based on one of characteristics of the camera, characteristics and positioning of the one or more glass plates, and relative dynamics of the camera and the object area; and rotating the one or more glass plates about one or more predetermined axes based on corresponding plate rotation rates and plate rotation angles.

Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: A high frequency data network access system leverages commodity WiFi chipsets and specifically multi spatial stream (e.g., 802.11 ac) chipsets in combination with electrically steered patch array antenna systems at the subscriber nodes. In addition, for thermal control, the high frequency components are mounted to a main body that includes a heat sink and a chimney. These components are also separated from components operating at baseband to avoid interference.

Abstract: An actuator component for a droplet ejection head; wherein said actuator component comprises a substrate and one or more strips of piezoelectric material fixedly attached to said substrate; wherein said one or more strips of piezoelectric material comprise one or more layers of piezoelectric material, and an array of fluid chambers defined within said one or more strips of piezoelectric material and extending in an array direction; wherein said actuator component further comprises one or more cover parts; wherein the or each cover part extends in said array direction and is fixedly attached to at least one of a side face of one of said strips of piezoelectric material and/or at least a portion of said substrate; and wherein said one or more cover parts comprise a plurality of openings so as to enable fluid to be supplied to selected ones of said fluid chambers through said openings. Associated methods of manufacturing an actuator component for a droplet ejection head are also provided.

Abstract: A high frequency data network access system leverages commodity WiFi chipsets and specifically multi spatial stream (e.g., 802.11 ac) chipsets in combination with electrically steered patch array antenna systems at the subscriber nodes. In addition, for thermal control, the high frequency components are mounted to a main body that includes a heat sink and a chimney. These components are also separated from components operating at baseband to avoid interference.

Abstract: Embodiments include an interface processing system for displaying interrelated hierarchical building system models. The interface processing system can include memory and a processor allocation to load an executable asset from a data store to instantiate an instance of a building management service that can receive from a client application executing an operator interface on a client device, a request to display a visual representation of an asset located in a building. The service can query an asset database including structured data associated with the asset. Location data can be used to generate a digital model of a building system location associated with the asset. The building management service can retrieve structured model data for the asset and system level components and extract, from a set of asset schemas, a hierarchical relationship between the asset, locations and the system level components to generate an interactive visual representation of the building system location.

Abstract: In one embodiment, a high speed induction machine includes: a stator formed of a first plurality of laminations having a thickness of less than approximately 0.01 inch and a winding comprising a coil formed of Litz wire adapted about the stator; and a rotor adapted within the stator. The rotor may include: a rotor core formed of a second plurality of laminations having a second thickness of greater than approximately 0.10 inch and formed of high strength steel and sandwiched between a first end region including at least one first peripheral second lamination and a second end region including at least one second peripheral second lamination, the first end region having a first end ring retained by a first retaining ring adapted there around, the second end region having a second end ring retained by a second retaining ring adapted there around.

Abstract: A high frequency data network access system leverages commodity WiFi chipsets and specifically multi spatial stream (e.g., 802.11 ac) chipsets in combination with electrically steered patch array antenna systems at the subscriber nodes. In addition, for thermal control, the high frequency components are mounted to a main body that includes a heat sink and a chimney. These components are also separated from components operating at baseband to avoid interference.

Abstract: A machine and method of reducing duplicate transmission data employs one more more digests to track field/value pairs that have previously been distributed. Each digest contains a record table and a segment table. The record table includes anonymous identifier records, each of which contain an anonymous identifier and one or more indexes into the segment table. The segment table comprises an array of every existing data field/value pair. Before distribution of update data, each record is matched to an anonymous identifier record in the record table. The segment values in the prospective distribution record are compared to the digest's anonymous identifier record, used to determine which data has already been distributed, and thus will be suppressed in the distribution.

Abstract: A system and method for protecting biological or other material from contamination through the steps of filling, freeze-drying, packaging, storing and use are disclosed. A system can include a flexible container, a membrane configured to transmit air or solvent vapor out of the flexible container, and a membrane frame supporting the membrane and engaged with at least one column member. The at least one column member can be configured to maintain the membrane and the membrane frame a spaced distance from one or more contents received within the flexible container. Upon application of a downward force, the at least one column member can assume a collapsed configuration. A method can include inserting a biological material, for example, into a flexible container, freeze-drying the biological material, moving the freeze-dried biological material to a portion of the flexible container that includes at least one port, and sealing the biological material within the portion.

Abstract: A machine and method of reducing duplicate transmission data employs one more more digests to track field/value pairs that have previously been distributed. Each digest contains a record table and a segment table. The record table includes anonymous identifier records, each of which contain an anonymous identifier and one or more indexes into the segment table. The segment table comprises an array of every existing data field/value pair. Before distribution of update data, each record is matched to an anonymous identifier record in the record table. The segment values in the prospective distribution record are compared to the digest's anonymous identifier record, used to determine which data has already been distributed, and thus will be suppressed in the distribution.

Abstract: In one embodiment, a high speed induction machine includes: a stator formed of a first plurality of laminations having a thickness of less than approximately 0.01 inch and a winding comprising a coil formed of Litz wire adapted about the stator; and a rotor adapted within the stator. The rotor may include: a rotor core formed of a second plurality of laminations having a second thickness of greater than approximately 0.10 inch and formed of high strength steel and sandwiched between a first end region including at least one first peripheral second lamination and a second end region including at least one second peripheral second lamination, the first end region having a first end ring retained by a first retaining ring adapted there around, the second end region having a second end ring retained by a second retaining ring adapted there around.

Abstract: A system and method for protecting biological or other material from contamination through the steps of filling, freeze-drying, packaging, storing and use are disclosed. A system can include a flexible container, a membrane configured to transmit air or solvent vapor out of the flexible container, and a membrane frame supporting the membrane and engaged with at least one column member. The at least one column member can be configured to maintain the membrane and the membrane frame a spaced distance from one or more contents received within the flexible container. Upon application of a downward force, the at least one column member can assume a collapsed configuration. A method can include inserting a biological material, for example, into a flexible container, freeze-drying the biological material, moving the freeze-dried biological material to a portion of the flexible container that includes at least one port, and sealing the biological material within the portion.

Abstract: A system and method for protecting biological or other material from contamination through the steps of filling, freeze-drying, packaging, storing and use are disclosed. A system can include a flexible container, a membrane configured to transmit air or solvent vapor out of the flexible container, and a membrane frame supporting the membrane and engaged with at least one column member. The at least one column member can be configured to maintain the membrane and the membrane frame a spaced distance from one or more contents received within the flexible container. Upon application of a downward force, the at least one column member can assume a collapsed configuration. A method can include inserting a biological material, for example, into a flexible container, freeze-drying the biological material, moving the freeze-dried biological material to a portion of the flexible container that includes at least one port, and sealing the biological material within the portion.

Abstract: Disclosed aspects relate to managing a database management system (DBMS). A central database to include a set of central data may be structured with respect to the DBMS. A blockchain database which is linked with the central database may be constructed with respect to the DBMS. A set of blockchain data may be established in the blockchain database corresponding to the set of central data of the central database. An access request may be received with respect to the DBMS. In response to receiving the access request, both the central database and the blockchain database may be maintained.