Patents by Inventor James Arnold
James Arnold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9029381Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.Type: GrantFiled: November 21, 2011Date of Patent: May 12, 2015Assignee: Astrazeneca ABInventors: James Arnold, Todd Andrew Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
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Publication number: 20140374342Abstract: The Environmental Waste Water Cultivation System is specifically designed without drainage or discharge facilities, to protect viable environments, including hydraulic systems. This system receives solid and aqueous waste and limits the amount of precipitation or condensation in an “on-demand” and variable fashion, to stabilize the system instantaneously and produces useable biomass. This system produces no discharge at any time and will function in any climate, every month.Type: ApplicationFiled: February 19, 2014Publication date: December 25, 2014Inventor: JAMES ARNOLD WILLIAMS, JR.
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Publication number: 20140350590Abstract: Assemblies, kits, and methods for occluding a vascular vessel, such as a varicose vein, are disclosed. An assembly can include a removable inner member, a removable outer member, and an elongated expandable member positioned in a compressed form between portions of the inner and outer members. To facilitate their removal, one or both of the inner and outer members can include a handle coupled to a proximal end. The elongated expandable member can include a gelatin material or a collagen material that is configured, when wetted, to expand from a compressed first diametrical size to a second larger diametrical size within a time period of 5 minutes or less. At the second larger diametrical size, the gelatin or collagen material can occlude a vascular vessel for a period of at least 20 days without degrading.Type: ApplicationFiled: June 6, 2014Publication date: November 27, 2014Inventors: Howard Root, James Arnold Murto, Stephen Anthony Penegor, Gregg Sutton
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Patent number: 8783627Abstract: A shield device for a switch point adjusting element used in combination with a railroad switch. The device includes first and second shells that mate with one another to form a cover having an inner chamber. The inner chamber is sized to loosely enclose the adjusting element. At least one boss having a recessed generally aligns with a guide having a passageway on the cover. A fastener extends at least partially through the passageway to the guide and engages the recess of the boss to hold the first and second shells together.Type: GrantFiled: January 4, 2013Date of Patent: July 22, 2014Inventors: James Arnold, Charles W. Bardsley
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Publication number: 20140125795Abstract: A trailer hitch alignment and coupling assistant is provided that is adapted to provide the driver of a towing vehicle with a clear indication of the relative positioning of the vehicle trailer hitch ball mount and the trailer coupler when maneuvering the towing vehicle. The system comprises a rear-mounted, downward facing imaging means and light source, which is adapted to capture the position of a first and second marker placed on the ball mount and trailer coupler, respectively. The image is communicated to a display unit within the vehicle cab for the operator to see the relative positioning of the two markers while reversing the vehicle. The markers are preferably reflective and visible in low light conditions. The rear-mounted image means comprises an operably mountable, wireless device, or alternately a hardwired device along the vehicle rear. Similarly, the display unit is a mountable fixture or hardwired into the vehicle cab.Type: ApplicationFiled: October 28, 2013Publication date: May 8, 2014Inventor: James Arnold Yerke
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Publication number: 20140096804Abstract: A leg supporting crutch apparatus includes a crutch having an underarm support structure, a support surface engagement structure, and a hand grip. A central portion of a torso engaging structure, which is between first and second end portion thereof, is attached to the central portion of the crutch at a location between the underarm support structure and the hand grip. A leg support assembly is attached to the central portion of the crutch at a location between the hand grip and the support surface engagement structure. The leg support structure includes a platform on which a lower leg portion of a person using the leg supporting crutch apparatus can be supported while the torso engaging structure is secured to a torso of the person and the underarm support structure is positioned under an armpit of the person.Type: ApplicationFiled: October 5, 2012Publication date: April 10, 2014Inventor: James Arnold Keck
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Patent number: 8539566Abstract: A system, method, and computer program product for monitoring managed resources by subscribing to broadcast notifications relayed by a Java Management Extensions (JMX) message bridge between JMX managed beans (JMX MBeans) and a client application with user interface (UI) components. In an embodiment, ADOBE™ FLEX™ user UI components subscribe to JMX broadcast notifications. The method generates messages destined for UI components using a JMX broadcaster. JMX MBeans are created in a JMX server and are subscribed to JMX broadcasts. The JMX MBeans are created with filter values identifying destination UI components. A JMX managed object name is passed to the UI during the creation of the UI components. The UI components become consumers of a message topic. A JMX message adapter dedicated to the communication with the JMX MBeans receives JMX broadcast notifications. Messages generated by the JMX broadcaster are relayed to the destination UI components through the JMX MBeans.Type: GrantFiled: April 14, 2010Date of Patent: September 17, 2013Assignee: Sybase, Inc.Inventors: James Arnold Peterson, Ilya Kagansky, Christopher Allen Bergin
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Publication number: 20130068897Abstract: A railroad switching apparatus utilizing a tie which is positioned under rails and points used in switching railroad cars. A support is interposed the tie and the rails and points and includes a passageway to guide the first and second indicator bars which are attached to the points. A slider is also employed at the attachment point of the indicator bars to the points to accommodate the thermal expansion and contraction of the rails and points. The indicator bars are formed into a coaxial unit in order to allow simple observation of the relative movement between the first and second indicator bars to determine proper movement of the points relative to the rails.Type: ApplicationFiled: September 20, 2011Publication date: March 21, 2013Inventor: James Arnold
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Patent number: 8367828Abstract: Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile.Type: GrantFiled: April 28, 2010Date of Patent: February 5, 2013Assignee: Plexxikon Inc.Inventors: James Arnold, Dean R. Artis, Clarence R. Hurt, Prabha N. Ibrahim, Heike Krupka, Jack Lin, Michael V. Milburn, Weiru Wang, Chao Zhang
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Publication number: 20120116046Abstract: A process for the preparation of diaminodinitropyridine or diaminodinitrobenzene by contacting an aminopyridine or aminobenzene with oleum and nitric acid, wherein the improvement comprises adding at least about 1% molar excess of nitric acid, based upon the aminopyridine or aminobenzene, with stirring for at least two hours to form first the intermediate sulfonic acid, and then diaminodinitropyridine or diaminodinitrobenzene, and use of such products in the preparation of rigid rod polymers is disclosed.Type: ApplicationFiled: January 9, 2012Publication date: May 10, 2012Applicant: E. I. DU PONT DE NEMOURS AND COMPANYInventors: HASAN DINDI, James Arnold Schultz
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Publication number: 20120065193Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.Type: ApplicationFiled: November 21, 2011Publication date: March 15, 2012Inventors: James Arnold, Andrew Todd Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
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Patent number: 8115007Abstract: A process for the preparation of diaminodinitropyridine or diaminodinitrobenzene by contacting an aminopyridine or aminobenzene with oleum and nitric acid, wherein the improvement comprises adding at least about 1% molar excess of nitric acid, based upon the aminopyridine or aminobenzene with stirring for at least two hours to form first the intermediate sulfonic acid, and then diaminodinitropyridine or diaminodinitrobenzene, and use of such products in the preparation of rigid rod polymers is disclosed.Type: GrantFiled: November 27, 2007Date of Patent: February 14, 2012Assignee: E. I. du Pont de Nemours and CompanyInventors: Hasan Dindi, James Arnold Schultz
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Patent number: 8063215Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.Type: GrantFiled: August 21, 2008Date of Patent: November 22, 2011Assignee: AstraZeneca ABInventors: James Arnold, Todd Andrew Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
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Publication number: 20110258688Abstract: A system, method, and computer program product for monitoring managed resources by subscribing to broadcast notifications relayed by a Java Management Extensions (JMX) message bridge between JMX managed beans (JMX MBeans) and a client application with user interface (UI) components. In an embodiment, ADOBE™ FLEX™ user UI components subscribe to JMX broadcast notifications. The method generates messages destined for UI components using a JMX broadcaster. JMX MBeans are created in a JMX server and are subscribed to JMX broadcasts. The JMX MBeans are created with filter values identifying destination UI components. A JMX managed object name is passed to the UI during the creation of the UI components. The UI components become consumers of a message topic. A JMX message adapter dedicated to the communication with the JMX MBeans receives JMX broadcast notifications. Messages generated by the JMX broadcaster are relayed to the destination UI components through the JMX MBeans.Type: ApplicationFiled: April 14, 2010Publication date: October 20, 2011Applicant: Sybase, Inc.Inventors: James Arnold Peterson, Ilya Kagansky, Christopher Allen Bergin
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Publication number: 20110143351Abstract: The present invention provides novel biomarkers for use in the diagnosis and prognosis of cancerous and malignant conditions and further of diseases which are mediated by a proinflammatory immune response. The biomarkers are glycoproteins, the levels of expression of which have been correlated by the inventors to correspond to particular disease conditions. The invention further extends to methods for use in monitoring the response to therapy of a treatment for use in the treatment of a cancerous condition or proinflammatory disease.Type: ApplicationFiled: July 21, 2008Publication date: June 16, 2011Inventors: Pauline Rudd, James Arnold, Radka Saldova, Louise Royle, Umi Marshida Abd Hamid, Raymond Dwek, Rosa Peracaula, Rafael De Llorens
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Publication number: 20110059992Abstract: This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.Type: ApplicationFiled: November 11, 2010Publication date: March 10, 2011Applicants: ASTRAZENECA AB, ASTEX THERAPEUTICS LTD.Inventors: James Arnold, Phil Edwards, Mark Sylvester, Stefan Berg, Jörg Holenz, Annika Kers, Karin Kolmodin, Laszlo Rakos, Liselotte Öhberg, Rotticci Didier, Gianni Chessari, Miles Congreve, Christopher Murray, Sahil Patel
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Patent number: 7903243Abstract: An improved refractometer for automatically determining the refractive index of a test subject by using principles embodied in Brewster's Angle, the refractometer comprising a light source, a light detector, a subject mount for securing the test subject to the device, a positioning device to orient the light source and light detector to the subject such that the angles of the light source and light detector to the subject are substantially identical, a data gathering device to automatically retrieve relevant data regarding the angles of the light source and light detector to the subject and the light intensity of the reflected light, and a computational device to process the data using algorithms taking into account the principles embodied in Brewster's Angle and/or Fresnel Equations in order to arrive at the refractive index of the test subject.Type: GrantFiled: November 19, 2009Date of Patent: March 8, 2011Inventors: James Arnold Vose, James Patrick McClymer, Thomas Woodrow Tripp, Jr.
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Patent number: 7872839Abstract: Methods, systems, and devices for controlling a serial arc fault in an electrical circuit are disclosed. In some embodiments, the methods include the following: a. measuring a current in the circuit; b. determining whether the current is below a predetermined value; c. if the current is below ten percent of the predetermined value, determining whether a countdown timer value indicated by a cell pointer value is equal to zero; d. if the countdown timer value is equal to zero, starting a countdown timer, advancing the cell pointer value by one, and restarting the method at step a.; e. if the countdown timer value is not equal to zero, determining whether the interruptions in the current are periodic; f. if the interruptions in the current are not periodic, checking whether an arc event countdown timer is running; and g. if the arc event countdown timer is running, tripping a circuit breaker.Type: GrantFiled: May 12, 2009Date of Patent: January 18, 2011Assignee: Astronics Advanced Electronic Systems Corp.Inventors: Frederick J. Potter, James Arnold Wright
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Patent number: 7855213Abstract: This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.Type: GrantFiled: June 13, 2007Date of Patent: December 21, 2010Assignees: AstraZeneca AB, Astex Therapeutics Ltd.Inventors: James Arnold, Phil Edwards, Mark Sylvester, Stefan Berg, Jörg Holenz, Annika Kers, Karin Kolmodin, Laszlo Rakos, Liselotte Öhberg, Rotticci Didier, Gianni Chessari, Miles Congreve, Christopher Murray, Sahil Patel
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Patent number: 7851584Abstract: Disclosed are processes for preparing monomer complexes that include contacting 2,3,5,6-tetraminopyridine free base in water with 2,5-dihydroxy terephthalic acid dipotassium salt to form an aqueous mixture, and adjusting the pH of the aqueous mixture to within the range of from about (3) to about (5) to precipitate the monomer complex. Processes of polymerizing the monomer complexes, polyareneazoles, filaments and yarns are also disclosed.Type: GrantFiled: March 27, 2006Date of Patent: December 14, 2010Assignees: E. I. du Pont de Nemours and Company, Magellan Systems International, LLCInventors: Doetze Jakob Sikkema, David J Rodini, Hasan Dindi, James Arnold Schultz, Georg Valentin Martin, Ralf Demuth, Michael Schelhaas