Abstract: A cleaning appliance of the cylinder type comprises a separating apparatus for separating dirt from a dirt-bearing fluid flow, and a floor-engaging rolling assembly. The separating apparatus comprises a first cyclonic separation unit having a low efficiency cyclone and a second cyclonic separation unit having a plurality of second cyclones. The rolling assembly comprises a main body having a recess in which the separating apparatus is received, and a plurality of floor-engaging wheels rotatably connected to the main body. The recess in the main body comprises a plurality of shaped recesses, each of which corresponds to the shape of at least a portion of a second cyclone. When the separating apparatus is received in the recess, a second cyclone is located at least partially in each shaped recess.

Abstract: A pen body assembly (100) for a drug delivery pen includes a pen body (101) and a dose setting body (111) movably connected to the pen body (101). A knob (109) is connected to the dose setting body (111) for moving the dose setting body (111) relative to the pen body (111). One of the pen body (101) and the dose setting body (111) has a thread groove (107) having a varied pitch disposed thereon and the other one has a protrusion (105) engaging the thread groove (107).

Abstract: An apparatus is disclosed for storing and changing needles for a medicament delivery device having a medicament container, including a fixed mount for connecting the apparatus with the medicament delivery device, a needle holder displaceable along a circuitous path and connecting a plurality of needles displaceably disposed thereon, and a guide member for guiding displacement of the needle holder, the guide member being disposed about the fixed mount. The apparatus also includes a user interface rotatably disposed about the fixed mount and having at least one internal engaging structure for displacing the needle holder along the circuitous path.

Abstract: A dual shield mechanism provides passive protection of a syringe cannula. The automatic shield system may be used with a re-fillable syringe, and may be adapted for filling the syringe from a vial using a novel vial adapter without triggering the passive shielding mechanism.

Abstract: A packaging tray for a patient interface system, the patient interface system adapted to provide respiratory therapy, the packaging tray comprising: at least one cushion assembly region, each shaped to conform to at least a portion of a cushion assembly; a tube region shaped to conform to at least a portion of a tube; and a positioning and stabilising structure region shaped to conform to at least a portion of a positioning and structure.

Abstract: A drug vial safety device, including a cover that is securable to a drug vial is disclosed. The cover at least partially encloses at least a neck and a lid of the drug vial. The cover includes a port having a shape that restricts syringe access to the vial through the port to a syringe shaped to be compatible with the port shape.

Abstract: A dual shield mechanism is provided for passive protection of a syringe cannula. The automatic shield system may be used with a re-fillable syringe, and may be adapted for filling the syringe from a vial using a novel vial adapter without triggering the passive shielding mechanism.

Abstract: Vial dosing systems and methods are disclosed. A vial dosing device includes a connecting body coupleable to a vial, a cannulated plunger having a proximal end coupled to the connecting body, a dose chamber adapted to slidably receive a distal end of the cannulated plunger and to expel medicament through a distal end of the dose chamber, and a plunger tip check valve coupled to the cannulated plunger and adapted for fluid flow from the cannulated plunger through the plunger tip check valve into the dose chamber.

Abstract: A high pressure delivery device for delivering a medicament includes a first chamber for storing a supply of the medicament and a second chamber in fluid communication with the first chamber. A fluid connection path is in fluid communication with the second chamber for administering the medicament. A valving system is in fluid communication with the first chamber, the second chamber and the fluid connection path. The valving system allows a dose of the medicament to be injected from the first chamber into the second chamber while substantially preventing backflow of the dose into the first chamber and substantially preventing leakage through the fluid connection path. The valving system also allows the dose in the second chamber to be administered through the fluid connection path while substantially preventing the dose from flowing back into the first chamber.