Abstract: An improved elastomeric material is described comprising an essentially noncross-linkable amorphous copolymer of tetrafluoroethylene (TFE) and perfluoromethyl vinyl ether (PMVE) which is both a thermoplastic and exhibits exceptional mechanical properties. This material is particularly suitable for use in ultra-clean environments, and particularly for use in an implantable device, since it does not contain contaminants that previous thermoset TFE/PMVE copolymers have required. Among the improved properties of the present invention are excellent biocompatibility, high matrix tensile strength, high clarity, high abrasion resistance, high purity, adequate elasticity, and ease of processing due to the thermoplastic, and noncross-linkable structure of the copolymer. The material of the present invention is also a high strength bonding agent particularly suited for bonding porous PTFE to itself or to other porous substances at room or elevated temperatures.

Abstract: Systems and methods for dynamically limiting total colorant coverage in multi-colorant rendering. Two polyhedra are defined: one contains all the colors that exceed the total colorant limit, and another is within the colorant limit that contains the results of the colorant limitation process. Data is received to identify a specified contone color, which is processed to decide whether it is inside one of the polyhedra. If the specified contone color is not within either polyhedra, the specified contone color is used in the rendering process. Alternatively, if the specified contone color is within one of the polyhedra, the value representing the specified contone color is compressed into the second polyhedra volume to obtain a resultant contone color that is used in the rendering process.

Abstract: Ophthalmic compositions include an ophthalmically acceptable carrier component, for example, an aqueous-based carrier, and a plurality of polyanionic component portions having different molecular weights. In one embodiment, the polyanionic component includes a first polyanionic component portion having a first molecular weight; and a second polyanionic component portion having a different second molecular weight. Each of the first and second polyanionic component portions is present in an amount effective to provide lubrication to an eye when the composition is administered to an eye. Methods of making and using such compositions are also disclosed.

Abstract: A liquid comprising a therapeutically effective concentration of a cyclosporin and a vitamin E tocopherol polyethylene glycol succinate, wherein said liquid is an aqueous solution, and wherein no hydrophilic organic solvent is present at a concentration greater than half of that of the cyclosporin is also disclosed herein. A composition comprising a therapeutically effective concentration of cyclosporin A and an effective amount of a vitamin E tocopherol polyethylene glycol succinate, wherein said composition is an aqueous liquid solution which is intended for ophthalmic use, and wherein no hydrophilic organic solvent is present at a mass concentration greater than or equal to that of the cyclosporin, is disclosed herein.

Abstract: A composition comprising a cyclodextrin, a guanidine-based cationic compound, and sorbic acid is disclosed herein. Preservatives and methods related thereto, and experimental results suggesting certain advantages related to these compositions, preservatives, and methods are also presented herein.

Abstract: A composition comprising a cyclodextrin, a guanidine-based cationic compound, and sorbic acid is disclosed herein. Preservatives and methods related thereto, and experimental results suggesting certain advantages related to these compositions, preservatives, and methods are also presented herein.

Abstract: Pharmaceutical compositions suitable for administration into the interior of an eye of a person or animal are described. The present compositions include one or more components which are effective in providing a reduced toxicity relative to existing intraocular ophthalmic compositions. The present compositions include one or more therapeutic agents in amounts effective in providing a desired therapeutic effect when placed in an eye, and one or more retinal friendly excipients that have a reduced toxicity relative to benzyl alcohol or polysorbate 80. In certain compositions, the excipient component of the compositions comprises one or more cyclodextrins or cyclodextrin derivatives. Methods of using the compositions to treat ocular conditions are also described.

Abstract: Biocompatible intraocular implants include an anti-excitotoxic agent and a biodegradable polymer that is effective to facilitate release of the anti-excitotoxic agent into an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants may be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as retinal damage, including glaucoma and proliferative vitreoretinopathy.

Abstract: Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months. The steroid may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants may be placed in an eye to treat one or more ocular conditions. The steroid is released from the implant for more than about two months, and may be release for more than several years.

Abstract: A device for detecting an actuator assembly parking error when a disc drive is powered on includes a magnetic latch attached to the actuator assembly and a latch pin assembly electrically connected to a base plate in the disc drive, where the latch pin assembly is positioned to contact the magnetic latch only when the actuator's read/write head is positioned over a parking zone on the disc. A detection module is electrically connected to the magnetic latch and thus is able to detect whether or not the magnetic latch is contacting the latch pin assembly when the disc drive is powered on. A method for detecting an actuator assembly parking error includes powering on the disc drive, determining whether the magnetic latch has electrical contact with the latch pin assembly, and reporting a parking error if the magnetic latch does not have electrical contact with the latch pin assembly.

Abstract: Disclosed herein are methods of delivering drugs or therapeutically active agents to the back of the eye via topical administration of compositions comprising cyclodextrin derivatives. Compositions related thereto are also disclosed herein.

Abstract: A crime scene fence post having a post base and an elongated post. The top end of the post has a lead-in notch, a slit, and a slot concatenated along the longitudinal axis of the post for easy installation and hold of a crime scene fence tape. The bottom end of the post has a tenon and the center of the post base has a mortise so that the post and the post base can be joined together to form a self-supported crime scene post.

Abstract: An integrated receiver with channel selection and image rejection substantially implemented on a single CMOS integrated circuit is described. A receiver front end provides programable attenuation and a programable gain low noise amplifier. Frequency conversion circuitry advantageously uses LC filters integrated onto the substrate in conjunction with image reject mixers to provide sufficient image frequency rejection. Filter tuning and inductor Q compensation over temperature are performed on chip. The filters utilize multi track spiral inductors with shields to increase circuit Q. The filters are tuned using local oscillators to tune a substitute filter, and frequency scaling during filter component values to those of the filter being tuned. In conjunction with filtering, frequency planning provides additional image rejection. The advantageous choice of local oscillator signal generation methods on chip is by PLL out of band local oscillation and by direct synthesis for in band local oscillator.

Abstract: Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include corticosteroid component-containing particles present in a therapeutically effective amount, a viscosity inducing component, and an aqueous carrier component. The compositions have viscosities of at least about 10 cps or about 100 cps at a shear rate of 0.1/second. In a preferred embodiment, the viscosity is in the range of from about 140,000 cps to about 300,000 cps. The compositions advantageously suspend the particles for prolonged periods of time.

Abstract: A method for recycling metals from swarf includes steps of removing oil in swarf by means of surfactant having a feature of strong hydrophilicity. The steps involves repeated stirring and washing, separating solid from liquid, and separating oil from water so as to force oil separate from the surface of solid, finishing all the steps in 10-30 minutes. Metals after finished the treatment may have only 1% of oil remained thereon, possible to be reused in metalworking. Oil and washing solution are also reusable after treated, so the method is effective both for treating waste and for recycling resources.

Abstract: A device for detecting an actuator assembly parking error when a disc drive is powered on includes a magnetic latch attached to the actuator assembly and a latch pin assembly electrically connected to a base plate in the disc drive, where the latch pin assembly is positioned to contact the magnetic latch only when the actuator's read/write head is positioned over a parking zone on the disc. A detection module is electrically connected to the magnetic latch and thus is able to detect whether or not the magnetic latch is contacting the latch pin assembly when the disc drive is powered on. A method for detecting an actuator assembly parking error includes powering on the disc drive, determining whether the magnetic latch has electrical contact with the latch pin assembly, and reporting a parking error if the magnetic latch does not have electrical contact with the latch pin assembly.

Abstract: Anaerobic hydrogen-producing process includes steps of producing hydrogen from organic waste under anaerobic condition, utilizing microorganisms, and of purifying hydrogen directly useable as fuel, and then transformed to become electric energy by a fuel cell.

Abstract: A method and system for monitoring and compensating the performance of an operational circuit is provided. The system includes one or more integrated circuit chips and a controller. Each integrated circuit chip includes one or more operational circuits, each operational circuit having at least one controllable circuit parameter. Each integrated circuit chip also includes a process monitor module at least partially constructed thereon. The controller is coupled to each process monitor module and to each operational circuit. The controller includes logic for evaluating the performance of an operational circuit based on data obtained from process monitor module and operational circuit related data stored in a memory. Based on the evaluation, the controller determines whether any deviations from desired or optimal performance of the circuit exist. If deviations exist, the controller generates a control signal to initiate adjustments to the operational circuit to compensate for the deviations.

Abstract: Methods of treating an eye of a human or animal include administering to an eye of a human or animal a composition in the form of an emulsion including water, a hydrophobic component and a cyclosporin component in a therapeutically effective amount of less than 0.1% by weight of the composition. The weight ratio of the cyclosporin component to the hydrophobic component is less than 0.8.

Abstract: The present invention provides for compositions for administering a therapeutically effective amount of a therapeutic component. The compositions may include an ophthalmically acceptable carrier component; a therapeutically effective amount of a therapeutic component; and a retention component which may be effective to reduce wettability, induce viscosity, increase muco-adhesion, increase meniscus height on a cornea of an eye and/or increase physical apposition to a cornea of an eye of a composition.