Patents by Inventor James L. Smith
James L. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11974916Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a prosthetic valve. The prosthetic valve may include a jacket configured to cover at least one of gaps, spaces, or interfaces in a frame or between one or more leaflets attached to the frame.Type: GrantFiled: September 16, 2021Date of Patent: May 7, 2024Assignee: Edwards Lifesciences CorporationInventors: David J. Arcaro, Kyle W. Colavito, Dustin V. Dienno, Cody L. Hartman, Roy Manygoats, Jr., Ryan S. Titone, Ryan D. Smith, Joshua A. Sprinkle, Benjamin A. Smith, James L. Goepfrich, Michael J. Shepard
-
Patent number: 11976036Abstract: Processes for producing n-heptane from a mixture of 1-hexene and 1-octene in the presence of a suitable isomerization-metathesis catalyst followed by a hydrogenation step are disclosed. Integrated manufacturing systems for producing n-heptane with minimal waste also are disclosed.Type: GrantFiled: June 21, 2023Date of Patent: May 7, 2024Assignee: Chevron Phillips Chemical Company LPInventors: Steven M. Bischof, Jeffery C Gee, James Hillier, Kamaljeet Kaur, Ronald C. Smith, Darin B. Tiedtke, Mark L. Hlavinka
-
Systems, methods, and graphical user interfaces for adding effects in augmented reality environments
Patent number: 11941764Abstract: A computer system displays a representation of a field of view of the one or more cameras, including a representation of a portion of a three-dimensional physical environment that is in the field of view of the one or more cameras. The computer system receives a request to add a first virtual effect to the displayed representation of the field of view of the one or more cameras. In response to receiving the request to add the first virtual effect to the displayed representation of the field of view of the one or more cameras and in accordance with a determination that the first virtual effect requires a scan of the physical environment, the computer system initiates a scan of the physical environment to detect one or more features of the physical environment and displays a user interface that indicates a progress of the scan of the physical environment.Type: GrantFiled: April 13, 2022Date of Patent: March 26, 2024Assignee: APPLE INC.Inventors: Andrew L. Harding, James A. Queen, Joseph-Alexander P. Weil, Joanna M. Newman, Ron A. Buencamino, Richard H. Salvador, Fernando Garcia, Austin T. Tamaddon, Omid Khalili, Scott W. Wilson, Thomas H. Smith, III -
Patent number: 11933285Abstract: A damped compressor used in mobile appliances. The appliances may comprise a compressor which is disposed within a housing and is in fluid communication with a refrigerant system. Within the housing there is an improved damping or stabilizer system which limits movement of electric or mechanical portions, or both, of the compressor within the housing. At startup and shutdown, when oscillations of the components within the housing are generally maximized, the components are limited from contacting the housing internal structure so as to inhibit damage to the compressor and reduce the noise associated with such contact. The components are also damped from movement associated with the mobile application of the compressor.Type: GrantFiled: April 19, 2019Date of Patent: March 19, 2024Assignee: Dometic Sweden ABInventors: James E. Allard, Mark L. Smith, Peng Wang
-
Patent number: 11934019Abstract: A light coupling unit includes a first major surface comprising one or more substantially parallel first grooves oriented along a first direction for receiving one or more optical waveguides. A second major surface for slidably contacting a mating light coupling unit comprises an optically transmitting window for propagating an optical signal therethrough, and a region of second grooves and lands configured to capture particulate contaminants in the second grooves.Type: GrantFiled: September 23, 2021Date of Patent: March 19, 2024Assignee: 3M INNOVATIVE PROPERTIES COMPANYInventors: James M. Nelson, Michael A. Haase, Terry L. Smith
-
Patent number: 11931312Abstract: A therapy system includes a patient support apparatus and a pneumatic therapy device that is coupleable to the patient support apparatus. The therapy device may receive power and air flow from the patient support apparatus.Type: GrantFiled: March 25, 2020Date of Patent: March 19, 2024Assignee: Hill-Rom Services, Inc.Inventors: Eric D. Benz, John G. Byers, Scott M. Corbin, Richard H. Heimbrock, Michael A. Knecht, Bradley T. Smith, Lori Ann Zapfe, Robert M. Zerhusen, Kenneth L. Lilly, Jonathan D. Turner, James L. Walke, Joseph T. Canter, Richard J. Schuman, Sr., John V. Harmeyer
-
Publication number: 20230144468Abstract: The present disclosure describes a unique, two-part, water-soluble polymer matrix material and a method of application that immobilizes a wide variety of loose powder or crystalline hazardous materials and renders them “safe” or at least “safer” for handling and transport. The polymer matrix material is a two-part polymer material comprising a liquid cross-linking polymer and a cross-linking agent, initiator, or biocide contained in a solution. The cross-linking agent functions to cross-link the polymer and cause it to harden in place.Type: ApplicationFiled: November 18, 2022Publication date: May 11, 2023Applicant: University of Rhode Island Board of TrusteesInventors: Jimmie Oxley, James L. Smith, Robert Ichiyama, Gerald Kagan
-
Publication number: 20230128640Abstract: A vehicular camera assembly includes a printed circuit board, a metallic shield element at least partially enclosing the printed circuit board, and a housing at least partially enclosing the shield element. The housing includes a front housing portion accommodating a lens. An imager is disposed at the printed circuit board and is optically aligned with the lens. The camera assembly includes an electrical connector for electrically connecting an electrical connecting element of the printed circuit board to a wire harness of a vehicle. The shield element includes at least one seam, with one or more seams including a respective gap between opposing edge regions of the shield element and an overlapping tab that extends from one of the opposing edge regions that at least partially closes the respective seam. The housing and the shield element are in contact.Type: ApplicationFiled: October 24, 2022Publication date: April 27, 2023Inventors: Nazar F. Bally, James L. Smith, Jonathan D. Conger
-
Publication number: 20230080152Abstract: Examples are directed toward collecting, by a LC-MS device, a full scan of ion chromatograms of a sample. The LC-MS device determines observed ions contained in the full scan, based on mass-to-charge ratios (m/z), and determines, for a formation curve of an observed ion, a formation point at which fifty percent of the observed ion has formed. The LC-MS device determines a fragmentation curve of a precursor ion, based on a fragmentation point of the fragmentation curve equivalent to the formation point at which fifty percent of the precursor ion has fragmented, and identifies the precursor ion by referencing the LC-MS library to confirm that the observed ion is a product of the fragmentation of the precursor ion. The LC-MS device indicates a goodness of fit between the fragmentation curve, as observed, and a model fragmentation curve, as stored in the LC-MS library.Type: ApplicationFiled: July 29, 2022Publication date: March 16, 2023Applicant: The Government of the United States of America, as represented by the Secretary of Homeland SecurityInventors: Jimmie Oxley, James L. Smith, Alexander Yevdokimov, Kevin Colizza
-
Publication number: 20220229017Abstract: The present disclosure describes an improved sample preparation technique, swab, swab holder and solvent for the removal of trace chemical materials from swabs and delivery of the trace materials into a mass spectrometer (MS) or an ion mobility spectrometer (IMS). The devices and techniques aid the delivery of the analyte into the instrument inlet and concurrently serves as an ionization source. The technique includes the steps of positioning or shaping the swab so that a pointed analyte release area is directed toward the inlet of the MS or IMS, adding a solvent to the swab and charging the swab to create an ionized analyte spray (Taylor Cone spray) into the inlet of the detection instrument. Solvent may include a chemical for depressing the ionization of residual solvent or enhancing the ionization of the desired analyte and this chemical may serve as an internal standard or benchmark.Type: ApplicationFiled: April 7, 2022Publication date: July 21, 2022Applicant: University of Rhode Island Board of TrusteesInventors: Jimmie Oxley, James L. Smith, Alexander Yevdokimov
-
Patent number: 11300542Abstract: The present disclosure describes an improved sample preparation technique and adapter device for the removal of trace materials from swabs and delivery of the trace materials into a mass spectrometer (MS) or an ion mobility spectrometer (IMS). The adapter device and technique aids the delivery of the analyte into the instrument inlet and concurrently serves as an ionization source. The technique includes the steps of positioning or shaping the swab so that a pointed analyte release corner or tip is directed toward the inlet of the MS or IMS, adding a solvent to the swab and charging the swab to create an ionized analyte spray pointed at or positioned within the inlet of the detection instrument.Type: GrantFiled: February 28, 2020Date of Patent: April 12, 2022Assignee: University of Rhode Island Board of TrusteesInventors: Jimmie Oxley, James L. Smith, Alexander Yevdokimov, Gerald Kagan
-
Publication number: 20220017431Abstract: The present disclosure describes a unique plasticized pyrotechnic material which can be easily portioned and formed or molded into a desired shape and which burns at a high temperature (>2000° C.) but does not detonate. The plasticized pyrotechnic material may preferably include a combination of about 70-99% by weight of a pyrotechnic composition and about 1-30% by weight of a plasticizer composition comprising various low to mid molecular weight polyisobutylenes. The pyrotechnic material comprises inorganic oxidizers (e.g. metal oxides, oxohalide salts, nitrates, nitrites, chlorates/perchlorates) and metal or metal oxides powders mixed intimately. The plasticizer may include a small amount of a fluoropolymer, such as polytetrafluoroethylene (PTFE) and may also include up to 1-2% by weight of a processed oil, such as a mineral oil or motor oil. Some embodiments may also include a biocide precursor molecule.Type: ApplicationFiled: March 16, 2021Publication date: January 20, 2022Applicant: University of Rhode Island Board of TrusteesInventors: Jimmie Oxley, James L. Smith, Taylor Busby, Athina Kominia
-
Patent number: 11225510Abstract: The subject invention pertains to a modified lantibiotic containing an intact cysteine at the C-terminus, particularly, a cysteine that is not decarboxylated and that contains a free carboxyl group. Derivatives of the modified lantibiotic comprising a moiety conjugated to the carboxyl group of the terminal cysteine are also provided. A bacterium that produces a modified lantibiotic having an intact cysteine at the C-terminus are also provided, wherein the bacterium is genetically modified to inactivate a gene that encodes a decarboxylase enzyme that decarboxylates the cysteine at the C-terminus of a precursor lantibiotic. Methods of producing a modified lantibiotic having an intact cysteine at the C-terminus by culturing a bacterium that synthesizes the modified lantibiotic and purifying the lantibiotic are also provided. Mutants of lantibiotics, particularly, mutacin 1140 having higher anti-bacterial activity or higher bacterial expression compared to mutacin 1140 are also provided.Type: GrantFiled: March 2, 2020Date of Patent: January 18, 2022Assignee: THE TEXAS A&M UNIVERSITY SYSTEMInventors: James L. Smith, Jerome Escano
-
Publication number: 20210169846Abstract: The subject invention pertains to methods for producing novel occidiofungin analogues lacking xylose (OF-?xyl analogue). OF-?xyl analogues can contain aldehyde, amine, triazole, or hydrazones. The aldehyde, amine, triazole or hydrazone containing analogues of OF-?xyl can be further modified by substitution with additional functional groups. Various OF-?xyl analogues described herein have reduced inflammation and toxicity and superior pharmacological properties compared to the natural occidiofungins. Accordingly, certain embodiments of the invention provide methods of treating or preventing fungal infections by administering to the subjects in need thereof the OF-?xyl analogues described herein.Type: ApplicationFiled: April 5, 2019Publication date: June 10, 2021Inventors: JAMES L. SMITH, MENGXIN GENG, AKSHAYA RAVICHANDRAN, RAVI ORUGUNTY
-
Publication number: 20200338377Abstract: The present disclosure describes a unique, two-part, water-soluble polymer matrix material and a method of application that immobilizes a wide variety of loose powder or crystalline hazardous materials and renders them “safe” or at least “safer” for handling and transport. The polymer matrix material is a two-part polymer material comprising a liquid cross-linking polymer and a cross-linking agent, initiator, or biocide contained in a solution. The cross-linking agent functions to cross-link the polymer and cause it to harden in place.Type: ApplicationFiled: March 13, 2020Publication date: October 29, 2020Applicant: University of Rhode Island Board of TrusteesInventors: Jimmie Oxley, James L. Smith, Robert Ichiyama, Gerald Kagan
-
Publication number: 20200292495Abstract: The present disclosure describes an improved sample preparation technique and adapter device for the removal of trace materials from swabs and delivery of the trace materials into a mass spectrometer (MS) or an ion mobility spectrometer (IMS). The adapter device and technique aids the delivery of the analyte into the instrument inlet and concurrently serves as an ionization source. The technique includes the steps of positioning or shaping the swab so that a pointed analyte release corner or tip is directed toward the inlet of the MS or IMS, adding a solvent to the swab and charging the swab to create an ionized analyte spray pointed at or positioned within the inlet of the detection instrument.Type: ApplicationFiled: February 28, 2020Publication date: September 17, 2020Applicant: University of Rhode Island Board of TrusteesInventors: Jimmie Oxley, James L. Smith, Alexander Yevdokimov, Gerald Kagan
-
Publication number: 20200199182Abstract: The subject invention pertains to a modified lantibiotic containing an intact cysteine at the C-terminus, particularly, a cysteine that is not decarboxylated and that contains a free carboxyl group. Derivatives of the modified lantibiotic comprising a moiety conjugated to the carboxyl group of the terminal cysteine are also provided. A bacterium that produces a modified lantibiotic having an intact cysteine at the C-terminus are also provided, wherein the bacterium is genetically modified to inactivate a gene that encodes a decarboxylase enzyme that decarboxylates the cysteine at the C-terminus of a precursor lantibiotic. Methods of producing a modified lantibiotic having an intact cysteine at the C-terminus by culturing a bacterium that synthesizes the modified lantibiotic and purifying the lantibiotic are also provided. Mutants of lantibiotics, particularly, mutacin 1140 having higher anti-bacterial activity or higher bacterial expression compared to mutacin 1140 are also provided.Type: ApplicationFiled: March 2, 2020Publication date: June 25, 2020Inventors: JAMES L. SMITH, JEROME ESCANO
-
Patent number: 10577399Abstract: The subject invention pertains to a modified lantibiotic containing an intact cysteine at the C-terminus, particularly, a cysteine that is not decarboxylated and that contains a free carboxyl group. Derivatives of the modified lantibiotic comprising a moiety conjugated to the carboxyl group of the terminal cysteine are also provided. A bacterium that produces a modified lantibiotic having an intact cysteine at the C-terminus are also provided, wherein the bacterium is genetically modified to inactivate a gene that encodes a decarboxylase enzyme that decarboxylates the cysteine at the C-terminus of a precursor lantibiotic. Methods of producing a modified lantibiotic having an intact cysteine at the C-terminus by culturing a bacterium that synthesizes the modified lantibiotic and purifying the lantibiotic are also provided. Mutants of lantibiotics, particularly, mutacin 1140 having higher anti-bacterial activity or higher bacterial expression compared to mutacin 1140 are also provided.Type: GrantFiled: October 30, 2017Date of Patent: March 3, 2020Assignee: THE TEXAS A&M UNIVERSITY SYSTEMInventors: James L. Smith, Jerome Escano
-
Patent number: 10265374Abstract: Disclosed are occidiofungin formulations and uses thereof for the treatment of proliferative disorders, such as cancer. Methods of producing the disclosed occidiofungin formulations are also provided. Further, methods of treating a subject with the formulations are provided. In some embodiments, the formulations include occidiofungin and one or more cyclodextrins. The formulations may optionally further comprise an additional chemotherapeutic agent for treating the proliferative disease, lipid vesicles, and/or aqueous solvents (including pharmaceutically acceptable buffers and/or exceipients).Type: GrantFiled: September 14, 2015Date of Patent: April 23, 2019Assignees: MISSISSIPPI STATE UNIVERSITY, THE TEXAS A&M UNIVERSITY SYSTEMInventors: James L. Smith, Stephen Pruett, Frank Austin, Shien Lu, Ravichandran Akshaya, Steven Laihing
-
Patent number: D845191Type: GrantFiled: December 18, 2017Date of Patent: April 9, 2019Assignee: International Truck Intellectual Property Company, LLCInventors: Chris Isamu Ito, Glen Joel Durmisevich, William D. Miller, David James Olsen, James L. Smith, Jr., James C. Box, Curtis L. Wilson