Abstract: The present invention generally relates to bacterial polypeptide display systems, libraries using these bacterial display systems, and methods of making and using these systems, including methods for improved display of polypeptides on the extracellular surface of bacteria using circularly permuted transmembrane bacterial polypeptides that have been modified to increase resistance to protease degradation and to enhance polypeptide display characteristics.

Abstract: The present invention generally relates to bacterial polypeptide display systems, libraries using these bacterial display systems, and methods of making and using these systems, including methods for improved display of polypeptides on the extracellular surface of bacteria using circularly permuted transmembrane bacterial polypeptides that have been modified to increase resistance to protease degradation and to enhance polypeptide display characteristics.

Abstract: A method of operating a liquid crystal display (LCD) device is disclosed. The device comprises an LCD screen held by a housing, a camera positioned within the housing, and a backlight arranged to illuminate the LCD screen. The method comprises displaying a first image on the LCD screen by setting a first set of elements of the LCD screen to transmit light and illuminating the LCD screen with the backlight. After switching off the backlight, a second set of elements is set to transmit light with colour filters off, and an image is captured with the camera. After capturing the image, a second image is displayed on the LCD screen by setting a third set of elements to transmit light and illuminating the LCD screen with the backlight.

Abstract: An appliance hub for use in an upper portion of an enclosure can include a substrate configured to be positioned in an upper portion of an enclosure. The appliance hub can include a climate control apparatus mounted on the substrate and the climate control apparatus can be configured to regulate a temperature within the enclosure. The appliance hub can include one or more lighting elements configured to provide light within the enclosure, a plurality of fluid lines connected to the substrate and configured to provide fluid service and return to the climate control apparatus, and/or a plurality of electrical connections connected to the substrate and configured to provide electrical power and/or data to at least one of the climate control apparatus and the one or more lighting elements.

Abstract: A utility cart has a lower platform comprising a lower recessed storage area, an upper platform comprising an upper recessed storage area, a plurality of legs extending upwardly from the lower platform and supporting the upper platform in spaced relationship from the lower platform, a handle extending from the raised platform, a plurality of wheels connected to the lower platform and rollably supporting the cart, a configurable divider for selective location in the upper recessed storage area for dividing the upper recessed storage area into a plurality of compartments, and one or more tool holders.

Abstract: A fluid cooled mold plate is disclosed. The fluid cooled mold plate has a front side, a rear side, and a perimeter that extends between its front and rear sides. A cooling chamber is formed within the mold plate. The cooling chamber has a front wall, a rear wall, and a perimeter wall that extends between the front and rear walls. An inlet fluid duct extends from a first side of the mold plate perimeter to a first end of the cooling chamber and an outlet fluid duct extends from a second side of the mold plate perimeter to a second end of the cooling chamber. The cooling chamber is occupied by a turbulence generating dispersion mesh that is secured between the front and rear walls the cooling chamber.

Abstract: The invention relates generally to polypeptides that include a cleavable moiety that is a substrate for at least one protease selected from matriptase and u-plasminogen activator (uPA), to activatable antibodies and other larger molecules that include the cleavable moiety that is a substrate for at least one protease selected from matriptase and u-plasminogen activator, and to methods of making and using these polypeptides that include a cleavable moiety that is a substrate for at least one protease selected from matriptase and u-plasminogen activator in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: An appliance hub for use in an upper portion of an enclosure can include a substrate configured to be positioned in an upper portion of an enclosure. The appliance hub can include a climate control apparatus mounted on the substrate and the climate control apparatus can be configured to regulate a temperature within the enclosure. The appliance hub can include one or more lighting elements configured to provide light within the enclosure, a plurality of fluid lines connected to the substrate and configured to provide fluid service and return to the climate control apparatus, and/or a plurality of electrical connections connected to the substrate and configured to provide electrical power and/or data to at least one of the climate control apparatus and the one or more lighting elements.

Abstract: A utility cart comprises a frame supported by first and second front wheels mounted for rotation about a front wheel axis and spaced apart by a first distance and first and second rear wheels mounted for rotation about a rear wheel axis and spaced apart by a second distance, and a bed mounted to the frame and configured for rotational movement between a transport position and a dumping position about a pivot axis, the pivot axis being located between the front wheel axis and the rear wheel axis, wherein the second distance is greater than the first distance and a width of the bed, whereby when the bed is moved to the dumping position the bed is located between the rear wheels.

Abstract: The invention relates generally to polypeptides that include a cleavable moiety that is a substrate for at least one matrix metalloprotease (MMP), to activatable antibodies and other larger molecules that include the cleavable moiety that is a substrate for at least one MMP protease, and to methods of making and using these polypeptides that include a cleavable moiety that is a substrate for at least one MMP protease in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: A striking tool is provided. The striking tool includes a head, a handle coupled to or extending from the head, and an insert. The head defines a striking surface and has an opening therein. The insert is removably insertable into the opening of the head. The insert includes a cartridge having an interior space, a damping member located in the interior space, and a body located in the interior space. The body is movable with respect to the cartridge in order to allow the damping member to dampen vibration in the head.

Abstract: Disclosed herein are embodiments of an oxygen torch cutting system. In one embodiment, the oxygen torch cutting system comprises a cutting torch supplied with an oxygen gas source, a fuel gas source, and a third gas source. The third gas source can be a mixture of hydrogen and oxygen gasses (HHO) or hydrogen gas (H2) and can be added to the fuel gas source. The oxygen torch cutting system can include one or more gas lines, gas control valves, and flashback arrestors. The addition of HHO or H2 gas to the fuel gas source can be facilitated by a tee connector. The inclusion of HHO or H2 gas into the fuel gas source increases the efficiency of the oxygen cutting torch system by replacing a significant amount of the fuel with less expensive HHO or H2 gas and increases the oxidation rate of metal and creates a cleaner flame.

Abstract: A method of analyzing images is performed at a computer system that is in communication with an image acquisition device having an image sensor. The method includes receiving a reference template that includes a sync region and an inspection region that is located at an offset from the sync region. The method also includes acquiring a continuous sequence of image frames from the image sensor and storing each of the image frames in a buffer within the computer system's memory. The method further includes, for each image frame in the buffer, determining whether the image frame includes a sub-region matching the sync region. The method also includes, in accordance with a determination that the image frame includes a sub-region matching the sync region, capturing an inspection region within the image frame at the offset from the sub-region, and storing the captured inspection region to a non-volatile portion of the memory.

Abstract: The invention relates generally to polypeptides that include at least a first cleavable moiety (CM1) that is a substrate for at least one matrix metalloprotease (MMP) and at least a second cleavable moiety (CM2) that is a substrate for at least one serine protease (SP), to activatable antibodies and other larger molecules that include these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease, and to methods of making and using these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: The invention relates generally to polypeptides that include at least a first cleavable moiety (CM1) that is a substrate for at least one matrix metalloprotease (MMP) and at least a second cleavable moiety (CM2) that is a substrate for at least one serine protease (SP), to activatable antibodies and other larger molecules that include these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease, and to methods of making and using these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: A new and distinct nectarine tree named ‘A-662CN’ which originated from a hand-pollinated cross of ‘A-421CN’ nectarine (female parent; unreleased breeding selection) x ‘A-334CN’ nectarine (male parent; unreleased breeding selection) made in 1993 is described. This new nectarine tree cultivar can be distinguished by its yellow, standard-acid, firm flesh, early-season ripening, high soluble solids content, outstanding flavor, good postharvest performance, and moderate tolerance to bacterial spot.