Abstract: Syringe positioning apparatus and methods are disclosed that provide for automated positioning of a syringe at an axially aligned position on a predetermined axis. The apparatus and methods employ first and second members having opposing surfaces that include first and second ramps, respectively, wherein the first ramp angles upward and away from the second member, and the second ramp angles upward and away from the first member. At least one of the first and second members may be advanceable toward the other by an actuator, wherein the first and second ramps may slidably engage a syringe and thereby elevate the syringe to the axially aligned position on the predetermined axis.

Abstract: Provided herein are antibodies that specifically bind a protein comprising an H1.0K180me2 antigen or a peptide thereof, methods of making such antibodies, and methods of using such antibodies for therapeutics and diagnostics.

Abstract: An Artificial Intelligence (AI) based document processing system receives a request including one or more of a message and documents related to a process to be automatically executed. A process identifier is extracted and used for retrieving guidelines for the automatic execution of the document processing task. Machine Learning (ML) models, each corresponding to a guideline, are used to extract data responsive to the guidelines. Based on the responsive data meeting the approval threshold and the automatic document processing task executed, one or more of a recommendation to accept or reject the request, and a corresponding letter can be automatically generated.

Abstract: Methods and systems of operating a gas turbine engine in a low-power condition are provided. In one embodiment, the method includes supplying fuel to a combustor by supplying fuel to a first fuel manifold and a second fuel manifold of the gas turbine engine. The method also includes, while supplying fuel to the combustor by supplying fuel to the first fuel manifold: stopping supplying fuel to the second fuel manifold; and supplying pressurized air to the second fuel manifold to flush fuel in the second fuel manifold into the combustor and hinder coking in the second fuel manifold and associated fuel nozzles.

Abstract: Various systems and methods are provided for identifying cylinder knock. In one example, cylinder knock may be identified based on a knock monitor that identifies knock based on output from a crankshaft speed sensor.

Abstract: A first plurality of block identifiers is sorted based, at least in part, on a measure of spatial locality. A second plurality of block identifiers is sorted based, at least in part, on the measure of spatial locality. At least the first plurality of block identifiers and the second plurality of block identifiers are incrementally merged into a third plurality of block identifiers based, at least in part, on the measure of spatial locality. A block of data corresponding to metadata associated with a plurality of block identifiers of the third plurality of block identifiers is updated.

Abstract: A concentrated solar thermal receiver is mounted on a tower to receive concentrated solar thermal energy from a concentrating array of solar reflectors. The receiver comprises a single layered array of tubes configured to carry a heat transfer fluid such as sodium and defining in combination an exposed concentrated solar thermal energy receiving surface. The array of tubes have a lower fluid inlet header communicating with an inlet conduit, and an upper fluid outlet communicating with an outlet conduit. The tubes are arranged in a serpentine configuration and define a fluid flow path which is predominantly transverse and upward. The receiver includes a thermally insulating cover movable between an open position and a closed position in which the solar thermal energy receiving surface is covered to block or reduce the incidence of solar flux on the tubes or to reduce heat loss from the array of tubes when they are not operational.

Abstract: The present disclosure is directed to methods for manufacturing wind turbine rotor blades and components thereof, e.g. using 3D printing. In one embodiment, the method includes forming a rotor blade structure having a first surface and an opposing, second surface, the first and second surfaces being substantially flat. Another step includes printing a leading edge segment of the rotor blade onto the first surface, wherein heat from the printing bonds the leading edge segment to the first surface. The method also includes rotating the rotor blade structure having the leading edge segment attached thereto. A further step includes printing a trailing edge segment of the rotor blade onto the second surface, wherein heat from the printing bonds the trailing edge segment to the second surface. Another step includes securing one or more fiber-reinforced outer skins to the leading and trailing edge segments so as to complete the rotor blade.

Abstract: There is described herein methods and system for correcting steady state errors in propeller speed by calculating a leakage flow rate as a function of engine and propeller parameters.

Abstract: The present disclosure is directed to a modular rotor blade constructed of thermoset and/or thermoplastic materials for a wind turbine and methods of assembling same. The rotor blade includes a pre-formed main blade structure constructed, at least in part, from a thermoset material. The rotor blade also includes at least one blade segment configured with the main blade structure. The blade segment(s) is constructed, at least in part, of a thermoplastic material reinforced with at least one fiber material.

Abstract: A drive train (T) for a wind-up injection device (1) for injecting a liquid drug comprises a torsional energy storage (9) adapted to be loaded or unloaded by a rotatable element (6), a rotatable user handle (8), a rotationally driveable expelling mechanism (5) adapted to expel the liquid drug and a clutch element (12) coupled with the torsional energy storage (9) via the rotatable element (6) and comprising a ratchet (12.4) for maintaining the rotatable element (6) at one of a number of discrete angular positions against the torque of the torsional energy storage (9). The clutch element (12) is adapted to transmit a torque from the user handle (8) via the rotatable element (6) to the torsional energy storage (9) or alternatively from the torsional energy storage (9) via the rotatable element (6) to the expelling mechanism (5), wherein the ratchet (12.4) is switchable from one position to an adjacent position by a torque transmitted from the user handle (8) to the torsional energy storage (9).

Abstract: The present invention relates to new pyrrolopyridine compounds having the structures of Formula (I)-(IV), wherein the R groups, A, B, C, D and n are as defined in the detailed description, and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.

Abstract: The present disclosure is directed to a mold assembly for vacuum forming a component. The mold assembly includes plurality of support plates and a plurality of mold plates removably coupled to the plurality of support plates. The plurality of mold plates is stacked and removably coupled together to form a mold configured for forming the component. Each mold plate including a first surface partially defining a top surface of the mold, a second surface spaced apart from the first surface, a third surface extending from the first surface to the second surface, and a fourth surface spaced apart from the third surface and extending from the first surface to the second surface.

Abstract: Methods for manufacturing a wind turbine rotor blade having a flatback airfoil configuration along at least a portion of a span of the rotor blade include providing a shell mold of the rotor blade. The method also includes laying up an outer skin layer of the rotor blade into the shell mold. Further, the method includes placing at least one pre-fabricated corner of the flatback airfoil configuration into the shell mold. The pre-fabricated corner(s) has a pointed edge. The method also includes infusing the outer skin layer with the pre-fabricated corner(s) to form the flatback airfoil configuration.

Abstract: Techniques for drone device control are provided. In one example, a computer-implemented method comprises establishing, by a plurality of drone devices respectively operatively coupled to processors and coordinating with one other, a defined region of a defined coordinate space of a geographic area, wherein the defined region is associated with an animal. The computer-implemented method also comprises monitoring, by the plurality of drone devices, a physical relationship between the animal and the defined region. The computer-implemented method can also comprise, in response to identifying that the physical relationship between the animal and the defined region fails to meet a criterion, performing, by the plurality of drone devices, a pattern of operations selected to alter the physical relationship between the animal and the defined region to satisfy the criterion.

Abstract: An apparatus and method for gripping a syringe utilizes four gripping members advanceable in different corresponding directions toward a predetermined axis to supportably engage a barrel of a syringe at corresponding circumferentially offset locations. A first motor may be utilized for co-driven advancement of the gripping members in tandem in the different corresponding directions toward the predetermined axis, and for retraction of the gripping members. The gripping members may include corresponding rollers, wherein a single one of the rollers may be rotated in an automated manner during supportive engagement of a syringe by the gripping members. A second motor may be utilized for driven rotation of the single roller. The disclosed embodiments may be utilized for supportive engagement of syringes having a range of syringe diameters.

Abstract: A LIDAR sensor is mountable to a vehicle exterior with a field of view including a vehicle interior view first portion and a vehicle exterior view first portion. Data can be received from the LIDAR sensor. A state of a vehicle occupant can be determined based at least in part on data from the LIDAR sensor.

Abstract: A Lidar system includes a casing, a light emitter stationary relative to the casing, and a photodetector pivotally supported by the casing. The system includes a reflector assembly and the light emitter is aimed at the reflector assembly. The reflector assembly includes a rotational shaft and a reflector is fixed to the rotational shaft. A rotational motor is engaged with the rotational shaft. The aim of the photodetector may be adjusted, and the rotational motor may independently adjust the reflector assembly to correspondingly aim the reflector assembly.