Abstract: In one embodiment, a data processing method comprises, using a first computer, in response to detecting a change in a data source: automatically generating a dataset comprising a subset of data from the data source, generating a unique dataset identifier, and associating the dataset identifier with the dataset in digital data storage; generating a display description that comprises: the dataset identifier; and for each particular graphical data display widget among one or more graphical data display widgets, instructions that specify a widget type, an order and one or more widget configuration values for the particular graphical data display widget; transmitting the display description to a second computer.

Abstract: A method and apparatus for removing a volatile component from a mixture are disclosed. The method and apparatus employ a crosslinked elastomer with a glass transition temperature ?+25° C. as the sorbent.

Abstract: A control system for minimizing the flow rate and energy consumption of a water pump in a vehicle. The control system and method correlate a climate thermal load value with the temperature of the coolant in a climate control cooling circuit. A correlation is performed by mapping the inputs to a desired pump flow rate that is determined to be necessary at a minimum to provide adequate cooling for the engine and for air conditioning or heating the vehicle.

Abstract: A system for retrieving information about a position of a mobile computing device for use in an application, which includes a network of local positioning docks (PDs), each capable of docking a mobile computing device by restricting three dimensions of a physical position of the mobile computing device near one of the PDs; a database capable of storing information about the positions of the PDs within the network; a calculator capable of determining, based on a position of a positioning dock (PD), the position of the mobile computing device; and an application programming interface (API) connected to the database and capable of outputting the position of a PD to the mobile computing device.

Abstract: A vehicle includes a disconnect clutch selectively coupling an engine and an electric machine. The vehicle further includes a mechanical pump driven by the electric machine and operable to pressurize fluid for the clutch. The vehicle includes a controller programmed to, in response to the electric machine being inoperable, activate an auxiliary starter to start the engine, activate an electric pump operable to pressurize fluid to the clutch, and operate the engine to drive the mechanical pump.

Abstract: 2-ketoacid decarboxylase enzymes, compositions encoding for 2 ketoacid decarboxylase enzymes, and host cells comprising such enzymes or compositions are provided

Abstract: Techniques for propagation of deletion operations among a plurality of related datasets are described herein.

Abstract: Provided are chimeric receptors for engineering cells for adoptive therapy, including T cells, and the genetically engineered cells. In some embodiments, the chimeric receptors, such as chimeric antigen receptors (CARs) are modified in a junction region by one or more amino acid modifications such that peptide fragments of such region exhibit a lower binding affinity for a human leukocyte antigen (HLA) and/or the region exhibits reduced immunogenicity, including following administration to a subject. In some aspects, also provided are methods and compositions for engineering and producing cells expressing such chimeric receptors, compositions containing the cells, and method for their administration to subjects. In some embodiments, features of the chimeric receptors and engineered cells containing the chimeric receptors result in methods that provide for increased or improved activity, efficacy and/or persistence.

Abstract: The invention features a vital sign monitor that includes: 1) a hardware control component featuring a microprocessor that operates as interactive, icon-driven GUI on an LCD; and, 2) a sensor component that connects to the control component through a shielded coaxial cable. The sensor features: 1) an optical component that generates a first signal; 2) a plurality electrical components (e.g. electrodes) that generate a second signal; and, 3) an acoustic component that generates a third signal. The microprocessor runs compiled computer code that operates: 1) the touch panel LCD; 2) a graphical user interface that includes multiple icons corresponding to different software operations; 3) a file-management system for storing and retrieving vital sign information; and 4) USB and short-range wireless systems for transferring data to and from the device to a PC.

Abstract: A method of analyzing signal quality in order to determine the operational characteristics of a measuring device uses a sampling device to monitor and analyze signal data that is generates by a measuring device or encoder. The sampling device is used to calculate and transmit data that characterizes the signals being generated by the measuring device. The method enables a user to interact with the sampling device, and this user interaction is mediated by a remote server. The method employs the sampling device to constantly monitor the signal data and then generate alerts whenever the measuring device is exhibiting characteristics that do not meet predefined thresholds. The sampling device periodically publishes the calculated characteristic data. Thus, enabling the user to understand the operational characteristics of the measuring device and predict when maintenance should be performed. The method enables the user to execute specific signal analysis processes when performing diagnostic tests.

Abstract: Provided are chimeric receptors for engineering cells for adoptive therapy, including T cells, and the genetically engineered cells. In some aspects, also provided are methods and compositions for engineering and producing the cells, compositions containing the cells, and method for their administration to subjects. In some embodiments, the cells, such as T cells, contain genetically engineered antigen receptors that specifically bind to antigens, such as a chimeric antigen receptor (CAR), and which contain an intracellular signaling domain capable of inducing TRAF6-mediated signaling. In some embodiments, features of the cells and methods provide for increased or improved activity, efficacy and/or persistence.

Abstract: Provided are cells, e.g., engineered immune cells, expressing recombinant or engineered molecules involved in metabolic pathways, such as those that promote or inhibit one or more metabolic steps, reactions, or pathways, for example, in T cells. Such molecules include those that induce or repress a particular functional outcome or metabolic event, for example, one that promotes differentiation or reprogramming into a particular phenotypic state, such as memory, long-lived, activated or activatable, non-exhausted, phenotype or stem-like phenotype. The cells generally further express an immune receptor, such as an antigen receptor, which may be an engineered receptor, such as a CAR or recombinant TCR, or may be a natural immune receptor. Also provided are cells, such as T cells, expressing such molecules and combinations thereof, compositions comprising such cells, nucleic acids such as vectors encoding the same, and methods of administration to subjects in adoptive cell therapy.

Abstract: A seafood showcase having a plurality of vertical dividers disposed on a bottom from a front wall to a rear wall, forming a plurality of sections. A plurality of perforated horizontal dividers is medially disposed on the bottom, bisecting each of the plurality of sections into a front compartment and a rear compartment. The front compartment has a drain, a perforated drain separator wall, and a perforated false bottom. The perforated false bottom is removably disposed on the bottom of the showcase within the front compartment, and the perforated false bottom has an at least one handle and a plurality of removable legs. A water feed system has a main line and a plurality of compartment lines with a first valve and a perforated dispersion mechanism. A plurality of vertical drainpipes is attached to the drain of the front compartment of each section of the plurality of sections.

Abstract: Systems and methods for starting an engine of a hybrid powertrain or driveline that includes an engine and a driveline disconnect clutch are described. In one example, a motor/generator rotates one side of an open driveline disconnect clutch that is coupled to a transmission, and then closes the open driveline disconnect clutch in response to motor/generator acceleration being less than a threshold.

Abstract: A vehicle includes an engine having a crankshaft, a transmission, an electric machine, and at least one controller. The transmission includes a torque converter having a turbine fixed to a turbine shaft that is driveably connected to driven wheels of the vehicle. The torque converter includes an impeller and a bypass clutch configured to selectively lock the impeller and the turbine relative to each other. The electric machine includes a rotor selectively coupled to the crankshaft via a disconnect clutch and fixed to the impeller. The at least one controller is configured to generate a first torque command for the electric machine that defines a magnitude equal to driver-demanded torque while the bypass clutch is locked. The controller is further configured to, in response to a reduction in fluid pressure supplied to the bypass clutch, generate a second torque command for the electric machine that defines a magnitude equal to driver-demanded torque plus impeller inertia torque.

Abstract: Embodiments of the present disclosure relate to a data analysis system that may automatically generate memory-efficient clustered data structures, automatically analyze those clustered data structures, and provide results of the automated analysis in an optimized way to an analyst. The automated analysis of the clustered data structures (also referred to herein as data clusters) may include an automated application of various criteria or rules so as to generate a compact, human-readable analysis of the data clusters. The human-readable analyses (also referred to herein as “summaries” or “conclusions”) of the data clusters may be organized into an interactive user interface so as to enable an analyst to quickly navigate among information associated with various data clusters and efficiently evaluate those data clusters in the context of, for example, a fraud investigation. Embodiments of the present disclosure also relate to automated scoring of the clustered data structures.