Abstract: In a first aspect, the present invention relates to a method of determining assembly, homogeneity and/or thermodynamic stability of biological macromolecular complexes. In particular, the method allows determining maximum stability of said complexes based on fluorescence changes at an appropriate wavelength as a function of temperature whereby said fluorescence changes reflect the status of assembly, homogeneity and/or thermodynamic stability of the biological macromolecular complexes. Said method is based on identifying two state and multistate unfolding fluorescence curves as a function of temperature by fitting said curves according to a multistate unfolding model. In addition, a computer program and a computer program storage medium as well as an apparatus and a system is provided for determining the assembly, homogeneity and/or thermodynamic stability of biological macromolecular complexes.

Abstract: A method of determining a degree of yaw error of a wind turbine is provided. The method includes obtaining wind pressure measurement values from in front of the rotor plane, which wind pressure measurement values exhibit a periodic nature related to a rotation of a spinner of the wind turbine, performing a signal processing step to process the wind pressure measurement values to determine a phase offset of the wind pressure measurement values relative to an angular reference, and deriving a yaw error angle from the phase offset. A method of establishing a relationship between a phase offset of wind pressure measurement values and a degree of yaw error of a wind turbine, a yaw error determination unit, and a wind turbine are also provided.

Abstract: A process for preparing nitric acid by: catalytically oxidizing ammonia, to obtain a gas mixture containing NO and O2; cooling and condensing the gas mixture, thereby further oxidizing NO with O2, to obtain a gas stream containing NO2/N2O4 and an aqueous solution containing nitric acid; and countercurrently absorbing the NO2/N2O4 from the gas stream in an absorber with process water (H2O), to obtain nitric acid and an NOx-containing absorber offgas, wherein the water content of the nitric acid is regulated to a concentration in the range from 50 to 77.8% by weight and the NOx content of the absorber offgas to a concentration in the range from 20 to 500 ppm, by continuously measuring the water content of the process air supplied to the catalytic gas phase oxidation and, as a function of this, adjusting the amount of process water (Q-H2O) fed to the absorber.

Abstract: The present invention relates to system for measuring pressure and temperature based on change in the characteristic properties of a medium for ultrasound under the effect of pressure and temperature. The invention is based on two waveguides where geometry is adapted to the medium's characteristic properties for ultrasound such that only planar pressure waves are generated in the waveguides. The first of the waveguides is arranged for measuring temperature due to thermal expansion of the medium, where the medium is pressure-compensated by means of an internal compensator to prevent thermal pressure accumulation, and where measuring temperature is based on the medium's specific known characteristic data for ultrasound under the effect of temperature under constant pressure.

Abstract: The present invention provides immediate release pharmaceutical compositions for oral administration that are resistant to abuse.

Abstract: The present disclosure relates to pharmaceutical compositions that are abuse resistant and may also provide controlled release. The present disclosure also relates to the use of pharmaceutical compositions in the treatment of pain.

Abstract: The present invention provides immediate release pharmaceutical compositions for Oral administration that are resistant to abuse.

Abstract: Controlled release formulations and methods for preparing controlled release formulations for delivery of active drug substances are described herein. The formulations described herein may be employed to produce pharmaceutical compositions, such as controlled release dosage forms, adjusted to a specific administration scheme.

Abstract: Controlled release formulations and methods for preparing controlled release formulations for delivery of active drug substances are described herein. The formulations described herein may be employed to produce pharmaceutical compositions, such as controlled release dosage forms, adjusted to a specific administration scheme.

Abstract: Controlled release formulations and methods for preparing controlled release formulations for delivery of active drug substances are described herein. The formulations described herein may be employed to produce pharmaceutical compositions, such as controlled release dosage forms, adjusted to a specific administration scheme.

Abstract: A measurement system is provided for a wind turbine having a plurality of rotor blades mounted to a spinner at the front of a nacelle and arranged to rotate in a rotor plane. The measurement system includes a measuring device for determining a pressure at a number of pressure measurement points. The pressure measurement points are arranged in front of the rotor plane, an analysis module for generating a control signal on the basis of the pressure measurements, and output means for issuing the control signal to a controller of the wind turbine.

Abstract: A device for a guide rail (1) for a scaffold (2), in which the guide rail (1) is connected to a building (4), and wherein the guide rail (1) is movable between an inactive, stowed away position and an active position.

Abstract: Driving arrangement (11) for a pump, compressor or similar, adapted to provide alternating pressure in at least two chambers (27a, 27b, 27?, 27?), such as chambers of a pump or compressor, as result of a reciprocating movement of a bar element (23). The bar element is connected to two movable pressure chamber faces being pistons (21a, 21 b) or plungers having fluid connection to said chambers, which bar element (23) is reciprocally supported in a housing (19). The driving arrangement further comprises an electric motor (31) which is adapted to provide the reciprocating movement of the bar element (23). The bar element extends through the rotor (31b) of the electric motor (31). The electric motor is an electric rotary motor. The invention also relates to a pump assembly with a plurality of such driving arrangements.

Abstract: The present invention relates to a method for determining drug resistance mutations in any of the non-structural protein regions NS3 to NS5B of Hepatitis C Virus (HCV) for genotypes 1 to 6, more in particular for subtype specific genotypes 1a, 1b, 2a, 2b, 3a, 4a and 4d.

Abstract: Process for purifying and cooling a gas stream comprising a dialkyl ester A) of an aromatic dicarboxylic acid, which comprises treating the gas stream with an aliphatic dihydroxy compound B) at a temperature less than/equal to the melting point of the dialkyl ester A) in a 1st stage and treating the gas stream with an aliphatic dihydroxy compound B) at above the melting point of the dihydroxy compound B) in at least one 2nd stage.

Abstract: A new class of polymeric additives for papermaking is disclosed as well as a process for their manufacture, a method for their use and a paper sheet containing the addition. The additives can be used in paper manufacture as agents for improving retention, paper machine operation and the strength properties of the product. The additives are manufactured from a microbial biomass. The biomass that contains acetyl amino groups or other amides is chemically modified by hydrolysis of the amides to form primary amino groups. Under neutral or acidic conditions these primary amines become cationic, which assures a good absorption of the additive onto fibres and fines of pulp that is generally of anionic nature.

Abstract: The present invention relates to a process for separating off carbon dioxide from gas mixtures by absorption using aqueous alkaline solutions, which comprises carrying out the absorption in a countercurrent flow apparatus in which the gas mixture which is to be worked up and the aqueous alkaline solution used are passed in countercurrent flow and wherein a discontinuous liquid phase forms in the interior of the countercurrent flow apparatus and the separation is carried out in the interior of the countercurrent flow apparatus in the presence of activated carbon, wherein the activated carbon is present in the interior of the countercurrent flow apparatus in an amount of 1 g to 2 kg of activated carbon per m3 of volume of the countercurrent flow apparatus.

Abstract: The present invention provides immediate release pharmaceutical compositions for oral administration that are resistant to abuse by intake of alcohol.

Abstract: The present invention provides immediate release pharmaceutical compositions for Oral administration that are resistant to abuse.

Abstract: The present invention relates to pharmaceutical compositions, which provide controlled release of a drug. The compositions are suitable for continuous administration as they remain effective throughout the treatment regimen. The present invention also relates to the use of the compositions for preparation of a medicament for continuous treatment of an individual.