Abstract: Compositions containing curable recombinant human collagen, and kits comprising same, which are usable in preparing modeling material formulations for additive manufacturing (e.g., 3D bioprinting) of 3D objects are provided. Methods utilizing such modeling material formulations in additive manufacturing of 3D objects having a collagen-based material in at least a portion thereof, are also provided. The formulations feature a desired viscosity at a temperature higher than 10° C. (e.g., room temperature or 37° C.) and allow performing the additive manufacturing without cooling the system or a part thereof.

Abstract: The invention relates to novel antibodies that bind to lymphotoxin beta receptor (LTBR) and to bispecific antigen binding molecules comprising these novel LTBR antibodies and an antigen binding domain that binds a tumor associated antigen, in particular to Fibroblast Activation Protein (FAP), to methods of producing these molecules and to methods of using the same.

Abstract: A package for a pharmaceutical product and method of assembly is described that includes a subassembly with a body including a main panel and legs depending downwardly from opposite edges of the main panel, and a sheet of plastic having opposite ends fixed to the body with the sheet of plastic at least partially extending over the main panel. The sheet of plastic is configured to be tensioned over and deformed around one or more primary containers to hold the one or more primary containers in place relative to the main panel of the body.

Abstract: Provided are systems and methods that rely on machine learning to recommend employment opportunities. In one example, a method may include identifying, via execution of a first machine learning model, income data and spending data of a user, identifying, via execution of a second machine learning model, skill attributes of the user, determining, via execution of a third machine learning model, a recommended job for the user, where the determining comprises inputting the outputs from the first and second machine learning models into the third machine learning model, and displaying, via a user interface, a description of the recommended job.

Abstract: A connector includes a shell, an insert that fits within the shell, and a socket that extends within the insert. The socket includes a hood, a body within the hood, an annular tine extending from the body within the hood, an annular lip extending around the tine adjacent an end of the tine, and a cavity formed within the tine.

Abstract: A hybrid multirotor propulsion system for an aircraft includes a plurality of propulsion units, each propulsion unit having a propeller, an electromotor and a peripheral differential gearbox; a plurality of driving elements, each of which is coupled to a respective one of the plurality of propulsion units; a mechanical power source; a main distributor gearbox; at least one electric machine; and a power management unit. The power management unit is configured according to a predetermined operating mode, which causes the mechanical power source to output first and second mechanical power components; and distributing the first mechanical power component to provide each driving element with a direct mechanical propeller power; and causes the electric machine to convert the second mechanical power component into electric power, part of which provides each electromotor with an electric propeller power.

Abstract: A tool for working a substrate, the tool having a stator and a working piston, which is intended to move relative to the stator along a working axis, also having a drive, which is intended to drive the working piston from a starting position along the working axis to the substrate, the drive comprising a piston coil arranged on the working piston and a first stator coil arranged on the stator, the piston coil having a piston coil axis, which is oriented transversely, to the working axis.

Abstract: The present teachings provide for a system comprising a gearbox including a gear assembly, the gearbox having an outer surface, the outer surface with a pair of apertures; and an actuator. The actuator including a support with a pair of lugs, with each lug having an opening; an drive system connected to the support; a shift fork including a pair of arms, the shift fork in communication with the drive system and configured to move a distance defining a stroke length between a disengaged position and an engaged position; and an actuation assembly operatively connected with the drive system to move the shift fork between a neutral position, and a shifted position, with a plurality of intermediate positions between the neutral and shifted positions. The actuator is mounted onto the outer surface of the gearbox, with the pair of lugs extending into the pair of apertures of the gearbox, and at least a portion of the shift fork extends extending through the lugs into and below the outer surface of the gearbox.

Abstract: The present-disclosure provides methods of treating cancer with certain co-activator of activator protein-1 and estrogen receptor (CAPER)-based polypeptides. In certain embodiments, the methods of the-disclosure target only cancerous cells without adversely affecting non-cancerous cells.

Abstract: The invention relates to new ethylene vinyl acetate-based polymer dispersions with increased stability compared to state-of-the-art and to a preparation process thereof. The invention also relates to a method for inhibiting wax deposition and reducing the pour point, viscosity and yield stress of crude oils by treating the crude oils with these stable ethylene vinyl acetate-based polymer dispersions.

Abstract: A cellularized nerve regeneration graft is disclosed that includes an electrospun biodegradable polymer conduit having an exterior surface and an interior luminal space, a plurality of fibroblasts seeded to the exterior surface of the conduit, and a system filling the interior luminal space of the conduit. The system may include a hydrogel matrix or augmented hydrogel matrix and Schwann cells. The cellularized nerve regeneration graft may be used in the repair of peripheral nerve injuries. Methods of making the cellularized nerve regeneration graft are also disclosed.

Abstract: Improved edge rings with flow conductance features are disclosed. The flow conductance features of the edge ring are features added to the edge ring that adjust the flow conductance of gas flowing in the local area of the edge ring. The flow conductance features can adjust the flow conductance to compensate for features on a semiconductor wafer, the edge ring, and in the chamber that may affect the flow of gas in the local areas. The flow conductance may be increased, reduced, or tuned depending on the desired effect.

Abstract: A method and to a device for processing a 3D point cloud representing surroundings, which is generated by a sensor. Initially, starting cells are identified based on ascertained starting ground points within the 3D point cloud which meet at least one predefined ground point criterion with respect to a reference plane divided into cells. Thereafter, cell planes are ascertained for the respective starting cells of the reference plane. Thereafter, estimated cell planes and ground points are ascertained for candidate cells deviating from the starting cells based on the cell planes of the starting cells, which are subsequently converted into final cell planes. As a result of such a cell growth originating from the starting cells, the cells of the reference plane are iteratively run through and processed so that the 3D point cloud is reliably classifiable into ground points and object points based on this method.

Abstract: The disclosure herein relates to photoinitiated dermal fillers, hyaluronic acid-rhCollagen double crosslinked dermal fillers and hyaluronic acid-rhCollagen semi interpenetrated network, each comprising plant-derived human collagen, as well as methods of using the same.

Abstract: A switchable polarizer includes a transparent layer and switchable material layer. The switchable material layer includes strips of a switchable material that are arranged to polarize incident light propagating through the transparent layer when the switchable material is heated to a threshold switching temperature. The incident light propagating through the transparent layer is unpolarized by the strips of the switchable material when the switchable material is below the threshold switching temperature.

Abstract: Dental retainer (1) configured to be applied on the lingual surface (L) of a predetermined number of teeth (T) of a dental arch (AD), comprising an adhesivation zone (2) anatomically configured to adhere to said lingual surface (L), and provided with an integrated positioner comprising positioning surfaces (22; 24) joined to the adhesivation zone (2) and spaced from the latter, said positioning surfaces (22; 24) being anatomically configured to come into contact with the respective teeth of the dental arch (AD) outside the adhesivation zone (2).

Abstract: Cyclic GMP-AMP synthase (cGAS) enzymes have been engineered to produce polypeptides having increased cGAS activity in the cyclization of modified nucleoside triphosphates, including thiolated or fluorinated nucleoside triphosphates, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing cGAS enzymes, compositions comprising the cGAS enzymes, and methods of using the engineered cGAS enzymes are useful for the production of pharmaceutical compounds.