Abstract: Systems and method are provided for defining map data used in controlling a vehicle. In one embodiment, a method includes: receiving, by a processor, telemetry data; determining, by the processor, distribution data of a path based on the telemetry data; determining, by the processor, a plurality of sample data based on a trained machine learning model and the distribution data; generating, by the processor, at least one of lane line data and road edge data based on the sample data and a second machine learning model; and storing, by the processor, the map data including the lane line data and road edge data for use in controlling the vehicle.

Abstract: The present invention provides a composition comprising (i) a cellulose-based polymer, and (ii) a plasticizer; wherein a weight per weight (w/w) concentration of the plasticizer within the composition is from 0.1 to 20%; and wherein a glass transition temperature (Tg) of the composition is reduced by at least 20% compared to a Tg of the cellulose-based polymer. Furthermore, provided herein are articles comprising the composition of the invention, and methods for manufacturing thereof.

Abstract: The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.

Abstract: Several embodiments of NO releasing structures are disclosed. In some embodiments, the structures are covalently modified to store and release nitric oxide. Some embodiments pertain to methods of making and use of these structures. The covalently modified polymer structures may be tailored to release nitric oxide in a controlled manner and are useful for treatment of various medical conditions.

Abstract: A device for magnetically detecting microscopic biological objects includes a microfluidic channel having a fluid inlet and a fluid outlet; a plurality of magnetic sensors arranged against an inner wall of the microfluidic channel; and a permanent magnet arranged against an outer wall of the microfluidic channel, in such a way that the plurality of magnetic sensors is immersed in a magnetic field created by the permanent magnet; the plurality of magnetic sensors including a first magnetic sensor; a second magnetic sensor opposite the first magnetic sensor; a third magnetic sensor downstream of the first and second magnetic sensors.

Abstract: A foundation construction machine includes a self-moving assembly for moving the machine on the ground, an excavation tool, at least one actuator for moving the excavation tool, at least one electric motor for supplying power to at least one movement of the machine. At least one interchangeable electric storage system is configured to assume a working condition, in which the interchangeable electric storage system is mechanically and electrically connected to the machine, and a replacement condition, in which interchangeable electric storage system is at least mechanically disconnected from the machine. Handling equipment is for bringing the at least one interchangeable electric storage system from the working condition to the replacement condition.

Abstract: Methods, apparatus, and articles of manufacture for observer-based landing control of a vehicle are disclosed. An example apparatus includes at least one memory, and at least one processor to execute instructions to at least in response to determining an aircraft is in a flight plan flare regime, determine an estimate state of an aircraft parameter based on an execution of a transfer function of an observer model, the execution of the transfer function based on an altitude command corresponding to the flare regime, determine a gain value based on the aircraft parameter, determine an altitude control input based on the estimate state and the gain value, determine an altitude command output based on the altitude control input and longitudinal dynamics of the aircraft, the longitudinal dynamics generated in response to the aircraft executing the altitude command output, and control an elevator of the aircraft based on the altitude command output.

Abstract: Systems, methods, and collection devices are disclosed for rapid, local PCR testing. The system may include a PCR testing module, memory configured to store computer-executable instructions, and at least one computer processor configured to access the memory and execute the computer executable instructions to: (i) receive an order for a PCR diagnostic test; (ii) associate a sample collection device (SCD) received by the PCR testing module with the order for a PCR diagnostic test; (iii) instruct the PCR testing module to conduct the PCR diagnostic test on a biological specimen in the SCD received by the PCR testing module; and (iv) cause presentation of results of the PCR diagnostic test.

Abstract: An agent, such as a detergent or cleaning agent, may include a polyesterase. A method for cleaning textiles may include applying the agent to a textile for removing soiling. The polyesterase may also help to reduce pilling effects in the agent.

Abstract: The current document is directed to an infrastructure-as-code (“IaC”) cloud-infrastructure-management service that allows users and upstream management systems to define and deploy infrastructure, such as virtual networks, virtual machines, load balancers, and connection topologies, within cloud-computing systems. The IaC cloud-infrastructure-management service includes a service frontend, a task manager, an event-processing component, and multiple Idem-service workers. The task manager manages execution of commands and requests received from the service frontend, using multiple queues, provides for prioritization of command-and-request execution by the multiple Idem-service workers, and provides for preemption of long-running executing commands and requests. The IaC cloud-infrastructure-management service can be scaled to efficiently handle dynamic workloads.

Abstract: An extruder assembly comprising a barrel, through which a conductor can travel; a first subassembly for extruding a first sleeve on the conductor; and a second subassembly for extruding a second sleeve onto the first sleeve, the second sleeve comprising a first portion, a second portion, and a cross-section comprising a first annulus sector and a second annulus sector, the first portion comprising the first annulus sector, the second portion comprising the second annulus sector, the first and second portions are in contact with the first sleeve.

Abstract: The present invention generally relates to antibodies that bind to HLA-A2/MAGE-A4, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.

Abstract: The present invention relates to hemi (L)-tartrate forms of the RSV fusion inhibitor 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (also known under its INN as rilematovir), and to processes for preparing said forms and the use of these forms in a pharmaceutical composition.

Abstract: Devices, systems, and methods for attaching solar modules to roofs. The devices may include a module hook clamp with a clamp body with clamp body arms extending upward from a clamp body base. The clamp body arms may include downward-facing hooks that engage a portion of the solar module's return flange and the outward-facing surface of the solar module. A spacer may optionally be positioned between the clamp body arms. The spacer may seat the solar module. A hook arm with a generally curve-shaped seating surface may extend below the clamp body base. The devices may further include a module attachment bracket that secures a second solar module in a similar manner as the module hook clamp. The module attachment bracket may include a platform that seats the hook arm of the module hook clamp, and a hook arm receiver that receives and secures the open end of the hook arm.

Abstract: An optical device includes a first set of electrodes; a second set of electrodes distinct and separate from the first set of electrodes; and a medium located between the first set of electrodes and the second set of electrodes. The medium includes a mixture of: liquid crystals and magnetic microstructures. The optical device is coupled with one or more magnetic field generators for switchably providing a magnetic field for orienting the magnetic microrods in the medium independently from the orientations of the liquid crystals. An optical device that includes a switchable optical cell and carbon nanotubes located within the switchable optical cell is also described.

Abstract: An optical device includes an optically dimmable filter that includes: a first set of electrodes; a second set of electrodes distinct and separate from the first set of electrodes; and a medium including electrochromic materials and liquid crystals between the first set of electrodes and the second set of electrodes. An optical device includes an optically dimmable filter that includes: a first spacer and a second spacer having distinct thicknesses; a first set of electrodes; a second set of electrodes separated from the first set of electrodes by the first spacer and the second spacer; and a medium including one or more electro-optic materials between the first set of electrodes and the second set of electrodes. A wearable display device that includes a display device and the optical device is also described.

Abstract: Antimicrobial compositions comprising at least an amine-based antimicrobial and an alkanolamine are disclosed. The disclosed compositions may be free of quaternary ammonium compounds. The disclosed compositions have antimicrobial properties and rapid efficacy against yeast and bacteria.

Abstract: An optical device includes an optically dimmable filter for providing a first set of scattering properties while the optically dimmable filter is in a first state and providing a second set of scattering properties while the first optically dimmable filter is in a second state. The optically dimmable filter also includes (i) a substrate with a plurality of surface features characterized by a first refractive index; (ii) a first set of one or more electrodes; (iii) a second set of one or more electrodes; and (iv) a medium having a second refractive index while the first optically dimmable filter is in a first state and a third refractive index distinct from the second refractive index while the first optically dimmable filter is in the second state. The first refractive index is closer to the second refractive index than the third refractive index.