Patents by Inventor Jason Hills

Jason Hills has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treatment of cancer
    Patent number: 8754078
    Abstract: The present invention relates to pyrroloquinolinyl-pyrrolidine-2,5-dione compounds in combination with chemotherapeutic agents. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention and also administering a effective amount of a chemotherapeutic agent.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: June 17, 2014
    Assignee: ArQule, Inc.
    Inventors: Chiang J. Li, Mark A. Ashwell, Jason Hill, Magdi M. Moussa, Neru Munshi
  • Corkscrew annuloplasty device
    Patent number: 8747462
    Abstract: An annuloplasty device includes a plurality of corkscrew anchors. The annuloplasty device further includes a core wire extending along the length of the device and at least one corkscrew wire which is operably connected to the corkscrew anchors to screw the corkscrew anchors into heart tissue. One or more of the corkscrew wires can include a drive key; the corkscrew anchors are connected to a sleeve with a keyway that engages the drive key on the corkscrew wires.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: June 10, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Jason Hill, Mark L. Jenson
  • COVERED STENT FOR VASCULAR CLOSURE
    Publication number: 20140114396
    Abstract: A stent assembly includes a stent, a covering on at least a portion of the stent, and a string encircling at least a portion of the covering. The string is releasably engaged to the covering or stent or both the covering and the stent. The string can be adhered to the stent, or the stent assembly, to the covering of the stent assembly, or both the covering and the stent. The string can be wrapped around the stent or covering in an interwoven loop or knit pattern. The covering can be made to overlap a perforation in a body lumen such as an artery or blood vessel and prevent bleeding.
    Type: Application
    Filed: December 23, 2013
    Publication date: April 24, 2014
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: Roger Hastings, Jason Hill
  • FOLDABLE MOBILITY DEVICE
    Publication number: 20140090910
    Abstract: A foldable mobility device includes a chassis assembly, a steering assembly rotatably coupled to the chassis assembly, a seat assembly coupled to the chassis assembly through a first folding mechanism configured to convert the seat assembly between a first folded position and a first unfolded position, a front wheel assembly coupled to the steering assembly and configured to be rotated by the steering assembly for steering the foldable mobility device, and one or more rear wheel assemblies coupled to the chassis assembly through a second folding mechanism configured to convert the one or more rear wheel assemblies between a second folded position and a second unfolded position.
    Type: Application
    Filed: September 30, 2013
    Publication date: April 3, 2014
    Applicant: ACTON, INC.
    Inventors: Peter TREADWAY, Janelle WANG TREADWAY, Enoch MORISHIMA, Jason HILL
  • Tether equipped catheter
    Patent number: 8685053
    Abstract: A catheter assembly comprises a manifold positioned at a proximal end of the catheter assembly. A tether member has a proximal end region fixedly engaged to a portion of the manifold. A proximal tubular member has a first end region engaged to the manifold. The proximal tubular member is disposed about at least a portion of the tether member. At least a portion of the tether member distal of the manifold is fixedly engaged to at least a portion of the proximal tubular member.
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: April 1, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Brian Brown, Jason Hill, John R. Moberg
  • Substituted Imidazopyridinyl-Aminopyridine Compounds
    Publication number: 20140073635
    Abstract: The present invention relates to substituted imidazopyridinyl-aminopyridine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted imidazopyridinyl-aminopyridine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Application
    Filed: November 8, 2013
    Publication date: March 13, 2014
    Inventors: Mark A. Ashwell, Chris Brassard, Anton Filikov, Jason Hill, Steffi Koerner, Jean-Marc Lapierre, Yanbin Liu, Nivedita Namdev, Robert Nicewonger, Rocio Palma, Manish Tandon, David Vensel, Akihisa Matsuda, Shin Iimura, Kenichi Yoshida, Takanori Yamazaki, Takahiro Kitamura, Takeshi Isoyama
  • Substituted imidazopyridinyl-aminopyridine compounds
    Patent number: 8609688
    Abstract: The present invention relates to substituted imidazopyridinyl-aminopyridine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted imidazopyridinyl-aminopyridine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: December 17, 2013
    Assignee: ArQule, Inc.
    Inventors: Mark A. Ashwell, Chris Brassard, Anton Filikov, Jason Hill, Steffi Koerner, Jean-Marc Lapierre, Yanbin Liu, Nivedita Namdev, Robert Nicewonger, Rocio Palma, Manish Tandon, David Vensel, Akihisa Matsuda, Shin Iimura, Kenichi Yoshida, Takanori Yamazaki, Takahiro Kitamura, Takeshi Isoyama
  • Grid Optimization Resource Dispatch Scheduling
    Publication number: 20130289772
    Abstract: Data comprising a request specifying a desired change in electrical load for a defined period of time is received. The electrical load is associated with a plurality of resources under control of resource agents and on a utility grid. Available capacity of resources within the control of each resource agent over the defined period of time is determined. Each available capacity is determined at least using a resource load model. Using the determined available capacity of resources over the defined period of time, resource scheduling instructions are calculated for a subset of resources. The resource scheduling instructions satisfy the desired change in electrical load of the request. Data characterizing the resource scheduling instructions is provided. Related systems, apparatus, methods, and articles are also described.
    Type: Application
    Filed: March 14, 2013
    Publication date: October 31, 2013
    Applicant: INNOVARI, INC.
    Inventors: Loran Friedrich, Eric Pierce, Jason Hill, James Tillett, Dave Walden, Laura Raymond, Chris Hickman, Phong Do
  • Handheld Vacuum Cleaner Tool Comprising a Vacuum Driven Motorized Brush
    Publication number: 20130263404
    Abstract: A vacuum cleaner device comprises a main body, a brush device, and a vacuum driven motor. The main body has a primary vacuum inlet, a secondary vacuum inlet, and a vacuum outlet. The secondary vacuum inlet is operatively connected to the vacuum outlet. The brush device is configured and adapted to reciprocate relative to the main body. The vacuum driven motor is adapted and configured to be rotationally driven by air passing through the secondary vacuum inlet to the vacuum outlet. The vacuum driven motor is operatively connected to the brush device in a manner such that rotation of vacuum driven motor causes the brush device to reciprocate relative to the main body.
    Type: Application
    Filed: April 6, 2012
    Publication date: October 10, 2013
    Applicant: RUG DOCTOR, INC.
    Inventors: Jason Hill, Charles Ostendorf, Vincent Lau
  • Compositions and methods for the treatment of cancer
    Patent number: 8513292
    Abstract: The present invention relates to pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound or pyrrolidine-2,5-dione compound of the present invention.
    Type: Grant
    Filed: June 19, 2008
    Date of Patent: August 20, 2013
    Assignee: ArQule, Inc.
    Inventors: Neil Westlund, Jason Hill, Mark A. Ashwell, Nivedita Namdev, Jianqiang Wang, Syed Ali
  • Substituted imidazopyridinyl-aminopyridine compounds
    Patent number: 8501770
    Abstract: The present invention relates to substituted imidazopyridinyl-aminopyridine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted imidazopyridinyl-aminopyridine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: August 6, 2013
    Assignee: ArQule, Inc.
    Inventors: Mark A. Ashwell, Chris Brassard, Anton Filikov, Jason Hill, Steffi Koerner, Jean-Marc Lapierre, Yanbin Liu, Nivedita Namdev, Robert Nicewonger, Rocio Palma, Manish Tandon, David Vensel, Akihisa Matsuda, Shin Iimura, Yuko Yamamoto
  • Compositions and methods for treatment of cancer
    Patent number: 8377927
    Abstract: The present invention relates to pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: February 19, 2013
    Assignee: ArQule, Inc.
    Inventors: Chiang J. Li, Mark A. Ashwell, Jason Hill, Magdi M. Moussa, Neru Munshi
  • Substituted Imidazopyridinyl-Aminopyridine Compounds
    Publication number: 20120329791
    Abstract: The present invention relates to substituted imidazopyridinyl-aminopyridine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted imidazopyridinyl-aminopyridine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Application
    Filed: June 21, 2012
    Publication date: December 27, 2012
    Applicant: ArQuele, Inc.
    Inventors: Mark A. Ashwell, Chris Brassard, Anton Filikov, Jason Hill, Steffi Koerner, Jean-Marc Lapierre, Yanbin Liu, Nivedita Namdev, Robert Nicewonger, Rocio Palma, Manish Tandon, David Vensel, Akihisa Matsuda, Shin Iimura, Kenichi Yoshida, Takanori Yamazaki, Takahiro Kitamura, Takeshi Isoyama
  • Substituted Imidazopyridinyl Compounds
    Publication number: 20120329793
    Abstract: The present invention relates to substituted imidazopyridinyl compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted imidazopyridinyl compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Application
    Filed: June 21, 2012
    Publication date: December 27, 2012
    Applicant: ArQule, Inc.
    Inventors: Mark A. Ashwell, Chris Brassard, Anton Filikov, Jason Hill, Steffi Koerner, Jean-Marc Lapierre, Yanbin Liu, Nivedita Namdev, Robert Nicewonger, Rocio Palma, Manish Tandon, David Vensel, Akihisa Matsuda, Shin Iimura, Yuko Yamamoto, Takeshi Isoyama
  • Corkscrew Annuloplasty Device
    Publication number: 20120296417
    Abstract: An annuloplasty device having a plurality of corkscrew anchors is herein disclosed. In some embodiments, the annuloplasty device includes a core wire extending along the length of the device, and at least one corkscrew wire which is operably connected to the corkscrews to screw the corkscrews into heart tissue. In certain embodiments, one or more of the corkscrew wires includes a drive key and the corkscrew anchors are connected to a sleeve with a keyway that engages the drive key on the corkscrew wires. In addition, in some embodiments, the device includes a retractable sheath, which is disposed over the corkscrews to protect them during insertion of the device.
    Type: Application
    Filed: September 23, 2011
    Publication date: November 22, 2012
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Jason Hill, Mark L. Jenson
  • Positioning Cage
    Publication number: 20120296160
    Abstract: A positioning device and method of using are provided herein. The positioning device includes an expandable cage through which blood can flow. The expandable cage is insertable into a bodily organ, for example a heart, and expanded to temporarily secure the positioning device within the organ. Then, the cage can be used to steady the implantation of an annuloplasty device, for example. Alternatively, the expanded cage can be used to locate a desired area or feature of the body organ in which it is inserted by way of fluoroscopy.
    Type: Application
    Filed: September 23, 2011
    Publication date: November 22, 2012
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Jason Hill, Scott R. Smith
  • Pyrrolidinone, pyrrolidine-2,5-dione, pyrrolidine and thiosuccinimide derivatives, compositions and methods for treatment of cancer
    Patent number: 8304425
    Abstract: The present invention relates to pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosucciniroide compounds of formulae (I)-(IV), and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound of pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compound of the present invention.
    Type: Grant
    Filed: June 19, 2008
    Date of Patent: November 6, 2012
    Assignee: ArQule, Inc.
    Inventors: Jianqiang Wang, Syed M. Ali, Eugene Kelleher, Yanbin Liu, Jason Hill, Mark A. Ashwell
  • Method of uniaxially expanding a fluoropolymer product
    Patent number: 8298462
    Abstract: This invention relates to a method of uniaxially expanding a fluoropolymer product including the steps of expanding a green fluoropolymer product in a first direction to create a first-expanded fluoropolymer product, and expanding the first-expanded fluoropolymer product in the same first direction. As a result with the subject invention, it has been found that ultra-high expansion and a variety of different porous/fibril structures can be achieved by using subsequent expansion steps in the same direction. Various considerations exist with such methodology, including the selection of rates of expansion of both steps, the amount of expansion of both steps, pre-heating and cutting the product between expansion steps. Although the present invention can be used with various fluoropolymer products, it is particularly well-suited for use with PTFE.
    Type: Grant
    Filed: December 30, 2004
    Date of Patent: October 30, 2012
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Michael Luk, Jeff Sewell, Jason Hill
  • Broad Spectrum ErbB Ligand Binding Molecules and Methods for Preparing and Using Them
    Publication number: 20120263707
    Abstract: Chimeric ErbB ligand binding molecules having detectable binding activity for more ErbB ligands than any one of native ErbB 1, ErbB3 or ErbB4 are disclosed. Preferably, the binding molecules bind a broad spectrum and, more preferably, the full spectrum of ErbB ligands. The chimeric ErbB ligand binding molecules generally have a subunit LI derived from one of ErbB1, 3, or 4 and a subunit LII derived from another distinct ErbB receptor type. The sub-domain, SI, which joins LI and LII can be from either one of the receptor types or can have portions from both. Pharmaceutical compositions that contain the molecules and methods for the treatment of ErbB sensitive diseases are also disclosed.
    Type: Application
    Filed: January 27, 2012
    Publication date: October 18, 2012
    Applicant: Ligacept, LLC
    Inventor: Jason Hill
  • Vehicle sunroof
    Patent number: D693759
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: November 19, 2013
    Assignee: Edison2 LLC
    Inventor: Jason Hill