Patents by Inventor Jay F. Kunzler

Jay F. Kunzler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10543076
    Abstract: A laser system for modifying the index of refraction of an optical hydrogel material. The laser system comprises a computer program to determine the position and shape of refractive structures to be written into the optical hydrogel material to correct a patient's vision, and a focused laser that generates laser light having a wavelength of from 400 nm to 900 nm, and which operates with an average power of 10 mW to 1000 mW to produce a pulse energy from 0.05 nJ to 1000 nJ with a peak intensity at focus of greater than 1013 W/cm2. The refractive structures exhibit a change in the index of refraction of 0.01 to 0.06 in the optical hydrogel material.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: January 28, 2020
    Assignee: University of Rochester
    Inventors: Wayne H. Knox, Li Ding, Jay F. Kunzler, Dharmendra M. Jani
  • Publication number: 20190240002
    Abstract: An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.
    Type: Application
    Filed: April 19, 2019
    Publication date: August 8, 2019
    Inventors: Wayne H. Knox, Li Ding, Jay F. Kunzler, Dharmendra Jani
  • Patent number: 10299909
    Abstract: An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: May 28, 2019
    Assignee: University of Rochester
    Inventors: Wayne H. Knox, Li Ding, Jay F. Kunzler, Dharmendra Jani
  • Publication number: 20190046357
    Abstract: A laser system for changing the index of refraction of cornea tissue in a living eye. The laser system comprises a laser that provides laser pulses with a wavelength from 400 nm to 900 nm and a pulse energy from 0.01 nJ to 10 nJ, and a control device for setting the operating parameters of the laser below an optical breakdown threshold of the tissue to avoid photo-disruption and tissue destruction of the tissue, and to direct the laser pulses at the cornea tissue resulting in a change in the index of refraction of the tissue within regions irradiated by the laser pulses.
    Type: Application
    Filed: October 17, 2018
    Publication date: February 14, 2019
    Inventors: Wayne H. Knox, Krystel R. Huxlin, Jay F. Kunzler, Li Ding
  • Patent number: 10160854
    Abstract: A dual reactivity crosslinking agent of formula I having at least two different reactive sites, and hydrogel materials prepared from at least two monomers with different rates of free-radical polymerization reactivity. The crosslinking agent includes at least one free-radical reactive site for vinyl-containing monomer and at least one free-radical reactive site for meth(acrylic)-containing monomer. The hydrogel materials are useful in the manufacture of biocompatible medical devices, for example, hydrogel materials having desirable physical properties useful as contact lens materials.
    Type: Grant
    Filed: August 1, 2016
    Date of Patent: December 25, 2018
    Assignee: GL Chemtec Vision Inc.
    Inventors: Gamil Alhakimi, Lisa H. Studnicki, Jay F. Kunzler
  • Publication number: 20170181846
    Abstract: An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.
    Type: Application
    Filed: March 10, 2017
    Publication date: June 29, 2017
    Inventors: Wayne H. Knox, Li Ding, Jay F. Kunzler, Dharmendra Jani
  • Patent number: 9622912
    Abstract: An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: April 18, 2017
    Assignee: University of Rochester
    Inventors: Wayne H. Knox, Li Ding, Jay F. Kunzler, Dharmendra Jani
  • Patent number: 9309357
    Abstract: A new synthetic method of forming free radical polymerizable end terminal functionalized poloxamers and poloxamines in commercial scale batches which uses a binary system of inhibitors to eliminate the formation of high molecular weight impurities. It has also been surprisingly discovered that the inorganic impurities formed during the commercial scale synthetic process are removed by the use of resin materials.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: April 12, 2016
    Assignee: Bausch & Lomb Incorporated
    Inventors: Alok Kumar Awasthi, Jay F. Kunzler, Ganugapati Satyanarayana, Satheesha Rai Nooji
  • Patent number: 9285508
    Abstract: Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a multi-armed macromonomer comprising multiple side chains attached to a nucleus, wherein each side chain comprises a thio carbonyl thio fragment of the same or different reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: March 15, 2016
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ivan M. Nunez, Jay F. Kunzler, Jeffrey G. Linhardt, Jennifer Hunt
  • Patent number: 9039174
    Abstract: The present application relates to novel monomers comprising polycarbosiloxane monomers useful in certain specific embodiments in the manufacture of devices. More particularly, the present application relates to certain ethylenically unsaturated free radical polymerizable monomers comprising polycarbosiloxane monomers. Even more particularly, the present application pertains to monomers comprising polycarbosiloxane monomers which further comprise at least two ethylenically unsaturated free radical polymerizable groups.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 26, 2015
    Assignee: Bausch & Lomb Incorporated
    Inventors: Alok Kumar Awasthi, Jay F. Kunzler
  • Publication number: 20150126979
    Abstract: An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.
    Type: Application
    Filed: December 9, 2014
    Publication date: May 7, 2015
    Inventors: Wayne H. Knox, Li Ding, Jay F. Kunzler, Dharmendra Jani
  • Patent number: 8932352
    Abstract: An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: January 13, 2015
    Assignee: University of Rochester
    Inventors: Wayne H. Knox, Li Ding, Jay F. Kunzler, Dharmendra Jani
  • Publication number: 20140371481
    Abstract: A new synthetic method of forming free radical polymerizable end terminal functionalized poloxamers and poloxamines in commercial scale batches which uses a binary system of inhibitors to eliminate the formation of high molecular weight impurities. It has also been surprisingly discovered that the inorganic impurities formed during the commercial scale synthetic process are removed by the use of resin materials.
    Type: Application
    Filed: June 18, 2014
    Publication date: December 18, 2014
    Inventors: Alok Kumar Awasthi, Jay F. Kunzler, Ganugapati Satyanarayana, Satheesha Rai Nooji
  • Patent number: 8828420
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic random copolymers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymer compositions comprise polymerized siloxane prepolymer containing pendant cationic and polymerizable groups.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: September 9, 2014
    Assignee: Bausch & Lomb Incorporated
    Inventors: Derek A. Schorzman, Joseph C. Salamone, Jay F. Kunzler
  • Patent number: 8827447
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polymerizable group containing polycarbosiloxane monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: September 9, 2014
    Assignee: Bausch & Lomb Incorporated
    Inventors: Alok Kumar Awasthi, Jason K. Stanbro, Jay F. Kunzler, Jeffrey G. Linhardt
  • Patent number: 8753389
    Abstract: A packaged, sterilized intraocular lens prepared by a process comprising providing a hydrophobic acrylic, or low water acrylic, intraocular lens and positioning the acrylic lens in a lens enclosure with an aqueous solution to provide a lens package. The lens package is then heated to a temperature sufficient for sterilization, however, the heating of the lens package must begin before the acrylic lens reaches an equilibrated, hydrated state following contact of the lens with the aqueous solution. The resulting sterilized acrylic intraocular lens will have less than sixty percent of total volume of disc-like features, or less than forty percent of total volume of water vacuoles, after 60 days following sterilization compared to an acrylic lens of the same composition, which was sterilized under the same conditions, but in an equilibrated, hydrated state.
    Type: Grant
    Filed: November 1, 2012
    Date of Patent: June 17, 2014
    Assignee: Bausch & Lomb Incorporated
    Inventor: Jay F. Kunzler
  • Publication number: 20130289294
    Abstract: The present application relates to novel monomers comprising polycarbosiloxane monomers useful in certain specific embodiments in the manufacture of devices. More particularly, the present application relates to certain ethylenically unsaturated free radical polymerizable monomers comprising polycarbosiloxane monomers. Even more particularly, the present application pertains to monomers comprising polycarbosiloxane monomers which further comprise at least two ethylenically unsaturated free radical polymerizable groups.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 31, 2013
    Inventors: Alok Kumar Awasthi, Jay F. Kunzler
  • Patent number: 8512320
    Abstract: The invention is directed to a method for correcting vision in a patient by modifying the refractive index of cornea tissue. The method comprises identifying and measuring the degree of vision correction of the patient; and determining the position and type of refractive structures to be written into the cornea tissue of the patient to correct the patient's vision. The refractive structures are written by irradiating select regions of the cornea tissue with focused laser pulses having a wavelength from 400 nm to 900 nm and a pulse energy from 0.01 nJ to 10 nJ. The refractive structures are characterized by a positive change in refractive index in relation to non-irradiated cornea tissue of the patient.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: August 20, 2013
    Assignees: Bausch & Lomb Incorporated, University of Rochester
    Inventors: Wayne H. Knox, Krystel R. Huxlin, Jay F. Kunzler, Li Ding
  • Patent number: 8486055
    Abstract: A method for modifying the refractive index of ocular tissues. The method comprises irradiating select regions of ocular tissue with a visible or near-IR laser. The irradiation results in the formation of structures in the ocular tissue, characterized by a change in refractive index, and which exhibit little or no scattering loss.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: July 16, 2013
    Assignees: Bausch & Lomb Incorporated, University of Rochester
    Inventors: Wayne H. Knox, Li Ding, Krystel R. Huxlin, Jay F. Kunzler
  • Publication number: 20130138093
    Abstract: An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.
    Type: Application
    Filed: November 28, 2012
    Publication date: May 30, 2013
    Applicants: University of Rochester, Bausch & Lomb Incorporated
    Inventors: Wayne H. Knox, Li Ding, Jay F. Kunzler, Dharmendra Jani, Candido D. Pinto