Patents by Inventor Jay F. Kunzler

Jay F. Kunzler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COATING SOLUTIONS COMPRISING SURFACE ACTIVE SEGMENTED BLOCK COPOLYMERS
    Publication number: 20090169716
    Abstract: This invention is directed toward surface treatment of a device. The surface treatment comprises the placing of surface active segmented block copolymers to the surface of the substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
    Type: Application
    Filed: December 16, 2008
    Publication date: July 2, 2009
    Inventors: Jeffrey G. Linhardt, Devon A. Shipp, Jay F. Kunzler
  • Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains
    Publication number: 20090168013
    Abstract: A method for reducing the modulus of polymer siloxane hydrogel compositions by employing monomeric polysiloxanes endcapped with trimethylsilyl to reduce the crosslinking density of the hydrogel. The synthesis consists of a single vessel acid catalyzed ring opening polymerization and may be employed to produce copolymers useful as hydrogel contact lens materials.
    Type: Application
    Filed: November 12, 2008
    Publication date: July 2, 2009
    Inventors: Jay F. Kunzler, Richard M. Ozark, Joseph A. McGee, Joseph C. Salamone
  • Method for Providing Lens Blanks
    Publication number: 20090146328
    Abstract: A method provides a machineable silicon-containing lens blank by removal of diluent from the lens blank. The method involves casting a lens blank in a mold, wherein the lens blank is made of a polymerization product of a monomeric mixture comprising a silicone-containing monomer and an organic diluent; removing the lens blank from the mold; and removing organic diluent from the lens blank.
    Type: Application
    Filed: October 28, 2008
    Publication date: June 11, 2009
    Inventors: Ronald J. Koch, Jay F. Kunzler, James A. Bonafini, JR.
  • High Water Content Silicone Hydrogels
    Publication number: 20090141234
    Abstract: Silicone hydrogels formed from a hydrated polymerization product of a monomer mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; and (b) a minor amount of a silicone-containing monomer, wherein the hydrogel has a water content of greater than 50 weight percent are disclosed.
    Type: Application
    Filed: November 10, 2008
    Publication date: June 4, 2009
    Inventors: Richard I. Blackwell, Jay F. Kunzler, Amy Jasek
  • Method For The Mitigation of Symptoms of Dry Eye
    Publication number: 20090142292
    Abstract: A method for the mitigation of symptoms of dry eye is disclosed. The method involves at least (a) incorporating one or more non-functionalized polymers having one or more hydrophilic moieties into an ophthalmic device that is a polymerization product of a comonomer mixture comprising: (i) a major amount of a non-silicone-containing hydrophilic monomer; and (ii) an end terminal functionalized surfactant; and (b) inserting the ophthalmic device in the eye of a patient.
    Type: Application
    Filed: November 7, 2008
    Publication date: June 4, 2009
    Inventors: Richard I. Blackwell, Jay F. Kunzler, Daniel M. Ammon, JR., Joseph C. Salamone
  • OPTICAL MATERIAL AND METHOD FOR MODIFYING THE REFRACTIVE INDEX
    Publication number: 20090143858
    Abstract: A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR laser having a pulse energy from 0.05 nJ to 1000 nJ. The irradiation results in the formation of refractive optical structures, characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material. The method can be used to modify the refractive index of an intraocular lens following the surgical implantation of the intraocular lens in a human eye.
    Type: Application
    Filed: November 30, 2007
    Publication date: June 4, 2009
    Inventors: Wayne H. Knox, Li Ding, Jay F. Kunzler, Dharmendra Jani, Candido D. Pinto
  • Process for Making Biomedical Devices
    Publication number: 20090142485
    Abstract: A process for treating a silicone hydrogel biomedical device, especially an ophthalmic lens such as a contact lens, involves: immersing the silicone hydrogel biomedical device with a mixture of an organic solvent and a hydrophilic, polymeric material, for a sufficient time that the device is swollen in volume by at least 30%; and removing the organic solvent from the device while retaining at least a portion of the hydrophilic polymeric material therein.
    Type: Application
    Filed: November 18, 2008
    Publication date: June 4, 2009
    Inventors: Yu-Chin Lai, Edmond T. Quinn, Weihong Lang, Daniel M. Ammon, JR., Jay F. Kunzler
  • Siloxane prepolymer containing pendant and end-capping cationic and polymerizable groups
    Patent number: 7528208
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic random copolymers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymer compositions comprise siloxane prepolymer containing pendant and end-capping cationic and polymerizable groups.
    Type: Grant
    Filed: November 30, 2006
    Date of Patent: May 5, 2009
    Assignee: Bausch & Lomb Incorporated
    Inventors: Derek A. Schorzman, Joseph C. Salamone, Jay F. Kunzler
  • USE OF SILYLATED SULFONATE MONOMERS TO IMPROVE CONTACT LENS WETTABILITY
    Publication number: 20090093596
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain hydrophilic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. The polymeric compositions comprise polymerizable hydrophilic siloxanyl monomers.
    Type: Application
    Filed: September 3, 2008
    Publication date: April 9, 2009
    Inventors: Joseph C. Salamone, Jay F. Kunzler
  • High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers
    Publication number: 20090076187
    Abstract: An intraocular lens comprising a polymer that is prepared from a monomer mixture comprising a monomer of formula G-D-Ar??(I) wherein Ar is a C6-C24 aromatic group having a hydrophilic substituent, D is a divalent linking group, and G is a reactive functional group selected from the group consisting of acryloyl, acryloyloxy, methacryloyl, methacryloyloxy and mercapto. The polymer has an equilibrium water content of greater than 4.5 percent by weight.
    Type: Application
    Filed: November 19, 2008
    Publication date: March 19, 2009
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark
  • High refractive-index, hydrophilic monomers and polymers, and ophthalmic devices comprising such polymers
    Patent number: 7495061
    Abstract: A hydrophilic, aromatic-based monomer has an aromatic group substituted with at least one hydrophilic substituent and a reactive functional group. Polymers comprising such a hydrophilic, aromatic-based monomers avoid or reduce the risk of forming vacuoles of absorbed water. Furthermore, such polymers have high refractive index, and, thus, are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.
    Type: Grant
    Filed: May 27, 2005
    Date of Patent: February 24, 2009
    Assignee: Bausch + Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark
  • Method for Modifying the Refractive Index of Ocular Tissues
    Publication number: 20090005764
    Abstract: A method for modifying the refractive index of ocular tissues. The method comprises irradiating select regions of ocular tissue with a visible or near-IR laser. The irradiation results in the formation of structures in the ocular tissue, characterized by a change in refractive index, and which exhibit little or no scattering loss.
    Type: Application
    Filed: June 26, 2008
    Publication date: January 1, 2009
    Inventors: Wayne H. Knox, Li Ding, Krystel R. Huxlin, Jay F. Kunzler
  • High refractive-index siloxy-containing monomers and polymers, and ophthalmic devices comprising such polymers
    Patent number: 7423108
    Abstract: Siloxy-containing monomers, macromonomers, or polymers have at least a siloxy-containing side group that comprises a refractive-index increasing substituent. Polymeric compositions comprising such siloxy-containing monomers, macromonomers, or polymers are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: September 9, 2008
    Assignee: Bausch & Lomb Incorporated
    Inventors: Jay F. Kunzler, Joseph C. Salamone, Richard M. Ozark
  • High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers
    Publication number: 20080183006
    Abstract: A hydrophilic, aromatic-based monomer has an aromatic group substituted with at least one hydrophilic substituent and a reactive functional group. Polymers comprising such a hydrophilic, aromatic-based monomers avoid or reduce the risk of forming vacuoles of absorbed water. Furthermore, such polymers have high refractive index, and, thus, are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.
    Type: Application
    Filed: April 1, 2008
    Publication date: July 31, 2008
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark
  • SYNTHESIS OF CATIONIC SILOXANE PREPOLYMERS
    Publication number: 20080182956
    Abstract: This application is directed toward an improved method of synthesizing cationic siloxane prepolymers as well as a specific cationic siloxane prepolymer having improved compatibility with monofunctional siloxanyl methacrylate monomers and medical devices containing the cationic siloxane prepolymer.
    Type: Application
    Filed: January 24, 2008
    Publication date: July 31, 2008
    Inventors: Jason K. Stanbro, Ivan M. Nunez, Jay F. Kunzler, Derek A. Schorzman
  • Vinylchloroformate-free synthesis of vinyl and allyl(thio) carbamates
    Patent number: 7402689
    Abstract: The invention generally relates to methods of forming vinyl(thio)carbamates and more particularly to a vinylchloroformate-free method of synthesizing (N-vinyloxycarbonyl)-3-aminopropyltris(trimethylsiloxysilane).
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: July 22, 2008
    Assignee: Bausch & Lomb Incorporated
    Inventors: David E. Seelye, Jay F. Kunzler, Joseph C. Salamone
  • PACKAGING SOLUTIONS
    Publication number: 20080152540
    Abstract: The present invention is directed to new and improved packaging systems for storing cationic ophthalmic devices such as cationic contact lenses and to methods for packaging such cationic ophthalmic devices with solutions to improve the comfort of the lenses during wear. In particular, the present invention is directed to a packaging system for storing a cationic ophthalmic device in a solution comprising an effective amount of an anionic polymer. Such solutions are retained on the surface of an unused lens for extended periods of time, resulting in surface modification that persists in the eye, which may provide significant improvement in the wetting properties of fresh lenses used for the first time and, moreover, even several hours after lens insertion, preventing dryness and improving lubricity.
    Type: Application
    Filed: December 22, 2006
    Publication date: June 26, 2008
    Applicant: BAUSCH & LOMB INCORPORATED
    Inventors: Derek A. Schorzman, Richard I. Blackwell, Jay F. Kunzler
  • Polymeric materials having enhanced ion and water transport property and medical devices comprising same
    Patent number: 7390863
    Abstract: A polymeric material having enhanced oxygen permeability and ion and water transport rates comprises units of a first monomer and a second monomer, which comprises linear poly(ethylene oxide), cyclic poly(ethylene oxide), or combinations thereof. Medical devices, such as ophthalmic devices, are made from such polymeric materials.
    Type: Grant
    Filed: August 30, 2005
    Date of Patent: June 24, 2008
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler
  • Surface Treatment of Biomedical Devices
    Publication number: 20080143957
    Abstract: A surface modified biomedical device is provided comprising a biomedical device having a coating on at least a portion thereof, the coating comprising a polymer or copolymer having one or more repeating units of the formula: wherein R independently is a C2-C20 hydrocarbon radical and n is an integer of 2 to 5000.
    Type: Application
    Filed: November 20, 2007
    Publication date: June 19, 2008
    Applicant: BAUSCH & LOMB INCORPORATED
    Inventors: Jeffrey G. Linhardt, Jay F. Kunzler
  • SILICONE CONTACT LENSES WITH WRINKLED SURFACE
    Publication number: 20080143956
    Abstract: At least one of the surfaces of a silicone contact lens is a wrinkled surface, providing the contact lens surface with a desired topography. The wrinkled surface may include random ridges, either over the entire surface of the lens, or in a desired pattern on the surface of the lens.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 19, 2008
    Applicant: BAUSCH & LOMB INCORPORATED
    Inventors: Ravi Sharma, Robert M. Braun, Daniel M. Ammon, Jay F. Kunzler, Yu-Chin Lai