Abstract: The present disclosure relates to recombinant rhesus cytomegalovirus (RhCMV) and human cytomegalovirus (HCMV) vectors encoding heterologous antigens, such as pathogen-specific antigens or tumor antigens, which may be used, for example, for the treatment or prevention of infectious disease or cancer. The recombinant RhCMV or HCMV vectors elicit and maintain high level cellular immune responses specific for the heterologous antigen while including deletions in one or more genes essential or augmenting for CMV replication, dissemination or spread.

Abstract: An HVAC controller may be controlled in response to a natural language audio message that is not recognizable by the HVAC controller as a command, where the natural language audio message is translated into a command recognizable by the HVAC controller. The HVAC controller may be a thermostat including a housing that houses a temperature sensor, a microphone, and a controller. The controller may identify a trigger phrase in an audio stream provided by the microphone. In response to identifying the trigger phrase, the controller initiates processing of the audio stream to identify a command following the trigger phrase and to generate a command understandable by the thermostat that instructs the controller to perform the identified command. The controller then executes the generated command understandable by the thermostat. A user may communicate with the thermostat via the microphone of the thermostat and/or a remote device having a microphone.

Abstract: An HVAC controller may be controlled in response to a natural language audio message that is not recognizable by the HVAC controller as a command, where the natural language audio message is translated into a command recognizable by the HVAC controller. The HVAC controller may be a thermostat and may include a housing that at least partially houses a control module, a microphone, a speaker, a display, and a voice recognition module. The voice recognition module recognizes a predetermined audible trigger from a recorded voice message or streamed voice message, and in response, provide one or more audio clips via the speaker and/or video clips via the display to assist users in operating the thermostat. A user may communicate with the thermostat via the thermostat and/or a remote device.

Abstract: Human cytomegalovirus vectors comprising heterologous antigens are disclosed. The vectors derived from the TR strain, are ganciclovir-sensitive, include active US2, US3, US6, US7 and UL131A genes, and have a deleterious or inactivating mutation in the UL82 gene preventing the expression of pp71.

Abstract: An HVAC controller may be controlled in response to a natural language audio message that is not recognizable by the HVAC controller as a command, where the natural language audio message is translated into a command recognizable by the HVAC controller. The HVAC controller may be a thermostat including a housing that houses a temperature sensor, a microphone, and a controller. The controller may identify a trigger phrase in an audio stream provided by the microphone. In response to identifying the trigger phrase, the controller initiates processing of the audio stream to identify a command following the trigger phrase and to generate a command understandable by the thermostat that instructs the controller to perform the identified command. The controller then executes the generated command understandable by the thermostat. A user may communicate with the thermostat via the microphone of the thermostat and/or a remote device having a microphone.

Abstract: An HVAC controller may be controlled in response to a natural language audio message that is not recognizable by the HVAC controller as a command, where the natural language audio message is translated into a command recognizable by the HVAC controller. The HVAC controller may be a thermostat and may include a housing that at least partially houses a control module, a microphone, a speaker, a display, and a voice recognition module. The voice recognition module recognizes a predetermined audible trigger from a recorded voice message or streamed voice message, and in response, provide one or more audio clips via the speaker and/or video clips via the display to assist users in operating the thermostat. A user may communicate with the thermostat via the thermostat and/or a remote device.

Abstract: A mechanism for control and configuration of a lighting system from a user interface. For instance, a wall module designed as a user interface for a tenant to control the system may be implemented so as to be used not only to control the lighting system but also to configure it. The lighting system may involve a controller, circuits of lights, relays, motion and ambient detectors, scenes, schedules, and more. An additional user interface such as a wall module may be connected to the lighting system for control and configuration of the system.

Abstract: The recombinant rhesus cytomegalovirus (RhCMV) and human cytomegalovirus (HCMV) vectors of this invention encode heterologous antigens, such as pathogen-specific antigens or tumor antigens, which may be used, for example, for the treatment or prevention of infectious disease or cancer. The recombinant RhCMV or HCMV vectors elicit and maintain high level cellular immune responses specific for the heterologous antigen while including deletions in one or more genes essential or augmenting for CMV replication, dissemination or spread.

Abstract: Disclosed are CMV vectors that lack active UL128, UL130, UL146 and UL147 proteins that may also comprise one or more microRNA regulatory elements (MRE) that restrict expression of the CMV. Immunization with the disclosed CMV vectors allow selection of different CD8+ T cell responses—CD8+ T cells restricted by MHC-Ia, MHC-II, or by MHC-E.

Abstract: A local thermostat for controlling an HVAC unit may include a controller programmed to execute a remote access function for remotely accessing and communicating with at least one remote thermostat over a communication channel. The remote access application may be configured to display at least one thermostat setting of at least one of the remote thermostats on the display of the user interface of the local thermostat. In some cases, the remote access application may allow a user to change one or more thermostat settings of at least one remote thermostat using the user interface of the local thermostat.

Abstract: Disclosed herein are recombinant CMV vectors comprising heterologous antigens and microRNA recognition elements to silence expression of CMV genes in the presence of microRNA derived from myeloid cells, an active UL128 protein and an active UL130 protein. Also disclosed are recombinant CMV vectors comprising heterologous antigens and microRNA recognition elements to silence expression of CMV genes in the presence of microRNA derived from myeloid cells, an inactive UL128 protein and an inactive UL130 protein. Also disclosed are methods of generating an unconventional immune response using these vectors. Such an immune response is characterized by generation of a CD8+ T cell response that is predominantly restricted by MHC-II.

Abstract: Particular aspects provide for use of the ?-herpesvirus Cytomegalovirus (CMV: e.g., RhCMV and HCMV) as a uniquely evolved “vector” for safely initiating and indefinitely maintaining high level cellular and humoral immune responses (against, e.g., HIV, SIV, TB, etc.). Particular aspects provide a method for treatment or prevention of, e.g., HIV, SIV or TB, comprising infection of a subject in need thereof with at least one recombinant CMV-based vector (e.g., HCMV or RhCMV) comprising an expressible HIV/SIV/TB antigen or a variant or fusion protein thereof. In particular embodiments of the method, infection is of an immunocompetent, HCMV or RhCMV seropositive subject. Additional aspects provide for RhCMV- and HCMV-based vaccine vectors, and versions thereof with suicide or safety means. Further aspects provide pharmaceutical compositions comprising the inventive CMV-based vaccine vectors.

Abstract: A mechanism for control and configuration of a lighting system from a user interface. For instance, a wall module designed as a user interface for a tenant to control the system may be implemented so as to be used not only to control the lighting system but also to configure it. The lighting system may involve a controller, circuits of lights, relays, motion and ambient detectors, scenes, schedules, and more. An additional user interface such as a wall module may be connected to the lighting system for control and configuration of the system.

Abstract: A mechanism for control and configuration of a lighting system from a user interface. For instance, a wall module designed as a user interface for a tenant to control the system may be implemented so as to be used not only to control the lighting system but also to configure it. The lighting system may involve a controller, circuits of lights, relays, motion and ambient detectors, scenes, schedules, and more. An additional user interface such as a wall module may be connected to the lighting system for control and configuration of the system.

Abstract: The present disclosure relates to recombinant rhesus cytomegalovirus (RhCMV) and human cytomegalovirus (HCMV) vectors encoding heterologous antigens, such as pathogen-specific antigens or tumor antigens, which may be used, for example, for the treatment or prevention of infectious disease or cancer. The recombinant RhCMV or HCMV vectors elicit and maintain high level cellular immune responses specific for the heterologous antigen while including deletions in one or more genes essential or augmenting for CMV replication, dissemination or spread.

Abstract: The present invention relates to recombinant rhesus cytomegalovirus (RhCMV) and human cytomegalovirus (HCMV) vectors encoding heterologous antigens, such as pathogen-specific antigens or tumor antigens, which may be used, for example, for the treatment or prevention of infectious disease or cancer. The recombinant RhCMV or HCMV vectors elicit and maintain high level cellular immune responses specific for the heterologous antigen while including deletions in one or more genes essential or augmenting for CMV replication, dissemination or spread.

Abstract: Retail use bags and food service napkins are separate commodity products today. My invention brings the two together into one combined product during the manufacturing process. The two machines used to make both products today with this invention come together as one machine to incorporate the napkins into the bags.

Abstract: An HVAC controller may be controlled in response to a natural language audio message that is not recognizable by the HVAC controller as a command, where the natural language audio message is translated into a command recognizable by the HVAC controller. Voice recognition software identifies a trigger phrase included in the natural language audio message and in response the HVAC controller performs an action. The voice recognition software may be used to create a natural language text based message from a recorded voice message or streamed voice message, where the natural language text based message is translated into the command recognizable by the HVAC controller. In response to the command, the HVAC controller may perform an action and/or respond with a natural language text based or audio message. A user may communicate with the thermostat via the thermostat and/or a remote device.

Abstract: An HVAC controller may be controlled in response to a natural language audio message that is not recognizable by the HVAC controller as a command, where the natural language audio message is translated into a command recognizable by the HVAC controller. The HVAC controller may be a thermostat including a housing that houses a temperature sensor, a microphone, and a controller. The controller may identify a trigger phrase in an audio stream provided by the microphone. In response to identifying the trigger phrase, the controller initiates processing of the audio stream to identify a command following the trigger phrase and to generate a command understandable by the thermostat that instructs the controller to perform the identified command. The controller then executes the generated command understandable by the thermostat. A user may communicate with the thermostat via the microphone of the thermostat and/or a remote device having a microphone.

Abstract: An HVAC controller may be controlled in response to a natural language audio message that is not recognizable by the HVAC controller as a command, where the natural language audio message is translated into a command recognizable by the HVAC controller. The HVAC controller may be a thermostat and may include a housing that at least partially houses a control module, a microphone, a speaker, a display, and a voice recognition module. The voice recognition module recognizes a predetermined audible trigger from a recorded voice message or streamed voice message, and in response, provide one or more audio clips via the speaker and/or video clips via the display to assist users in operating the thermostat. A user may communicate with the thermostat via the thermostat and/or a remote device.