Abstract: Antibodies are provided which comprise at least one Fab portion that binds CD47 and at least one Fab portion that binds the tumor associated antigen (TAA) CD20; wherein the Fab portion that binds CD47 exhibits low affinity for CD47; and, wherein the Fab portion that binds CD20 exhibits high affinity for CD20; and, wherein the antibody selectively binds CD47 and blocks CD47 interaction with SIRP? in tumor cells while exhibiting no substantial binding to CD47 in normal cells.

Abstract: A method of maintaining a body of water in a usable condition where a sensor located in the body of water transmits information on water conditions to a server with the server including a database with the server generating a first maintenance recommendation if it is determined that the body of water contains a synergistic chemical combination and a different recommendation if it is determined that the body of water does not contain a synergistic chemical combination even though the transmitted information on the water conditions are the same.

Abstract: Structures for a varactor diode and methods of forming same. The structure comprises a first semiconductor layer including a section on a substrate, a second semiconductor layer on the section of the first semiconductor layer, a third semiconductor layer on the second semiconductor layer, and a doped region in the section of the first semiconductor layer. The section of the first semiconductor layer and the doped region have a first conductivity type, and the second semiconductor layer comprises silicon-germanium having a second conductivity type opposite to the first conductivity type, and the third semiconductor layer has the second conductivity type. The doped region contains a higher concentration of a dopant of the first conductivity type than the section of the first semiconductor layer. The second semiconductor layer abuts the first section of the first semiconductor layer along an interface, and the doped region is positioned adjacent to the interface.

Abstract: A snowmobile throttle control system comprises a throttle block with a throttle thumb lever pivotally connected thereto, the throttle block clamped to a snowmobile handlebar next to a right hand grip. The hand grip and/or thumb lever having electric heaters. The configuration of the throttle block and thumb lever reducing issues associated with snow and or ice buildup between the two during operation of the throttle control system by vertically and horizontally spacing respective confronting portions of each, effecting shear forces on any such ice or snow between the two, and by minimizing heat transfer between the handlebar and throttle block by reducing the contact between clamping surfaces of the throttle block engaging the handlebar thereby minimizing melting and freezing of the snow and ice at the throttle control system. The thumb lever and throttle block providing integrated securement structure for wires associated with the electric heaters.

Abstract: Antibodies are provided which comprise at least one Fab portion that binds CD47 and at least one Fab portion that binds the tumor associated antigen (TAA) CD20; wherein the Fab portion that binds CD47 exhibits low affinity for CD47; and, wherein the Fab portion that binds CD20 exhibits high affinity for CD20; and, wherein the antibody selectively binds CD47 and blocks CD47 interaction with SIRP? in tumor cells while exhibiting no substantial binding to CD47 in normal cells.

Abstract: The present invention provides cervical implant (30) comprising an upper surface (38), a lower surface (40), a posterior portion (34) and an anterior portion (36) and including a perimeter (42) and one or more apertures (44,46) within said anterior portion for receiving securing means, said apertures having respective longitudinal axes M1, M2, characterised in that said axes extend in a direction substantially through said anterior portion (36) and converge at a point in a plane outside of said perimeter (42).

Abstract: A snowmobile throttle control system comprises a throttle block with a throttle thumb lever pivotally connected thereto, the throttle block clamped to a snowmobile handlebar next to a right hand grip. The hand grip and/or thumb lever having electric heaters. The configuration of the throttle block and thumb lever reducing issues associated with snow and or ice buildup between the two during operation of the throttle control system by vertically and horizontally spacing respective confronting portions of each, effecting shear forces on any such ice or snow between the two, and by minimizing heat transfer between the handlebar and throttle block by reducing the contact between clamping surfaces of the throttle block engaging the handlebar thereby minimizing melting and freezing of the snow and ice at the throttle control system. The thumb lever and throttle block providing integrated securement structure for wires associated with the electric heaters.

Abstract: A method for conserving resources in a distributed system includes receiving an event-criteria list from a resource controller. The event-criteria list includes one or more events watched by the resource controller and the resource controller controls at least one target resource and is configured to respond to events from the event-criteria list that occur. The method also includes determining whether the resource controller is idle. When the resource controller is idle, the method includes terminating the resource controller, determining whether any event from the event-criteria list occurs after terminating the resource controller, and, when at least one event from the event-criteria list occurs after terminating the resource controller, recreating the resource controller.

Abstract: Structures for a heterojunction bipolar transistor and methods of forming a structure for a heterojunction bipolar transistor. The structure comprises an emitter, a collector including a first section, a second section, and a third section positioned in a first direction between the first section and the second section, and an intrinsic base disposed in a second direction between the emitter and the third section of the collector. The structure further comprises a stress layer including a section positioned to overlap with the emitter, the intrinsic base, and the collector. The section of the stress layer is surrounded by a perimeter, and the first and second sections of the collector are each positioned adjacent to the perimeter of the stress layer.

Abstract: An electronics system has a board with a thermal interface having an exposed surface. A thermoelectric device is placed against the thermal interface to heat the board. Heat transfers through the board from a first region where the thermal interface is located to a second region where an electronics device is mounted. The electronics device has a temperature sensor that detects the temperature of the electronics device. The temperature of the electronics device is used to calibrate an accelerometer and a gyroscope in the electronics device. Calibration data includes a temperature and a corresponding acceleration offset and a corresponding angle offset. A field computer simultaneously senses a temperature, an acceleration and an angle from the temperature sensor, accelerometer and gyroscope and adjusts the measured data with the offset data at the same temperature. The field computer provides corrected data to a controlled system.

Abstract: The present invention provides cervical implant (30) comprising an upper surface (38), a lower surface (40), a posterior portion (34) and an anterior portion (36) and including a perimeter (42) and one or more apertures (44,46) within said anterior portion for receiving securing means, said apertures having respective longitudinal axes M1, M2, characterised in that said axes extend in a direction substantially through said anterior portion (36) and converge at a point in a plane outside of said perimeter (42).

Abstract: An orthopedic plate is specifically configured for use in osteotomies, in which part of the plate extends into a portion of a first bone segment and part is external to the cortical surface of an adjacent bone segment to fix the segments to allow them to fuse. The plate has a first end and a second end where the end which is inserted into the bone has a chamfer and a through hole having a hole axis optionally at an oblique angle to the longitudinal axis of the plate, and which can receive a screw, peg or pin. The second end of the plate includes a locking screw hole and optionally including a compression slot extending in a direction toward a screw hole in the opposing end. Optionally, the non-locking hole has a shroud that forms an arc or portion of a cylinder over the hole. A plate driver having a recess that holds the plate is used to insert the plate into the bone.

Abstract: A method for conserving resources in a distributed system includes receiving an event-criteria list from a resource controller. The event-criteria list includes one or more events watched by the resource controller and the resource controller controls at least one target resource and is configured to respond to events from the event-criteria list that occur. The method also includes determining whether the resource controller is idle. When the resource controller is idle, the method includes terminating the resource controller, determining whether any event from the event-criteria list occurs after terminating the resource controller, and, when at least one event from the event-criteria list occurs after terminating the resource controller, recreating the resource controller.

Abstract: An electronics system has a board with a thermal interface having an exposed surface. A thermoelectric device is placed against the thermal interface to heat the board. Heat transfers through the board from a first region where the thermal interface is located to a second region where an electronics device is mounted. The electronics device has a temperature sensor that detects the temperature of the electronics device. The temperature of the electronics device is used to calibrate an accelerometer and a gyroscope in the electronics device. Calibration data includes a temperature and a corresponding acceleration offset and a corresponding angle offset. A field computer simultaneously senses a temperature, an acceleration and an angle from the temperature sensor, accelerometer and gyroscope and adjusts the measured data with the offset data at the same temperature. The field computer provides corrected data to a controlled system.

Abstract: A biocompatible material for bone repair is described. The bone repair composition includes a mixture of a type I collagen, a type I collagen-glycosaminoglycan coprecipitate, tricalcium phosphate; and bioactive glass. Methods of using the composition for bone repair, and a kit for the bone repair composition are also described.

Abstract: A biocompatible material for bone repair is described. The bone repair composition includes a mixture of a type I collagen, a type I collagen-glycosaminoglycan coprecipitate, tricalcium phosphate; and bioactive glass. Methods of using the composition for bone repair, and a kit for the bone repair composition are also described.

Abstract: A pen cap for a medication delivery pen includes a piston-style detector mechanism. The piston-style detector mechanism includes at least an inner shell having first open end through which the medication delivery pen can be inserted, a second end opposite the first end, a sidewall defined by an outer surface and an opposing inner surface, and a passageway extending from the outer surface to the inner surface. The sidewall extends between the first end and the second end thereby defining a pen-receiving cavity there between. The piston-style detector mechanism further includes at least one switch and a translatable shaft at least partially disposed in the passage. The translatable shaft includes a body that extends at least from a pen-interfacing portion in the pen-receiving cavity to a switch-interfacing portion thereof.

Abstract: An orthopedic plate has a first end including a locking screw hole that receives a locking screw and spaced from that hole is a closed compression housing that extends from the bone-facing side of the plate and which receives a compression screw that forms an angle of from about 10° to about 70° with a longitudinal axis of the plate. The compression housing is not located on the medial line of the plate, but is peripheral to the medial line, either in the longitudinal or the medial direction of the plate.

Abstract: Described herein is a weight or pressure measuring shovel. The shoveling apparatus has a broad blade assembly or scoop assembly including an elongate handle member. A coupler assembly is designed to couple the curved plate assembly to allow angular orientation or movement of the curved plate assembly to be adjusted relative to the handle member. A force transducer converts the weight or pressure of a material on the curved plate assembly into an electrical signal designed to communicate the weight or pressure of a material such as snow, sand, dirt, or ice. A control module in a housing mounted on the elongate handle is designed to receive electrical signals from the force transducer assembly or a load cell assembly. A display assembly is coupled to the electrical scale assembly and control module.