Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange and/or surface heat exchange.

Abstract: Preparing a metrologically-relevant entangled state includes: providing a plurality of atoms in a regular lattice, wherein each atom is in an initial quantum state of a first state in a ground state manifold; initializing a central atom in the regular lattice to a (|0+|1)/?2 state while all other atoms remain in the first state |0 as remaining atoms; and proceeding, starting with the central atom, to propagate preparation of Greenberger-Horne-Zeilinger (GHZ) states in a nonlinear progression by increasing a number of GHZ states in each iteration through the remaining atoms in a recursive manner, to produce an intermediate GHZ state, such that the intermediate GHZ state acts as an initial GHZ state for a next iteration, until a final GHZ state is formed to prepare the metrologically-relevant entangled state of the atoms.

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.

Abstract: A tool which is relatively simple in design, is easy to manufacture and assemble, and which is capable of dispensing precise amounts of the fluid contents of a deformable tube until the contents have been substantially completely dispensed is provided. The tool includes interlocking casing halves and a rigid actuator jaw which is adapted to be pressed against the tube to dispense the contents of the tube.

Abstract: Devices and methods for cooling all or part of the body of a human or animal subject by inserting a heat exchange catheter into the subject's body and infusing into or through the catheter a heat exchange medium that contains liquid phase matter and frozen solid phase matter, wherein at least some of the solid phase matter melts while in the catheter.

Abstract: The present disclosure includes devices, systems and related methods useable for controlling a patient's body temperature by endovascular heat exchange as well as body surface heat exchange.

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.

Abstract: Examples for a traction system are provided. In one example, the traction system includes a nozzle coupled to an air source and configured to be selectively aimed toward a determined portion of a rail surface of a rail, and a conduit configured to supply pressurized air from the air source to the nozzle, the nozzle flexibly coupled thereto. The nozzle is configured for the aim of the nozzle to be controlled to change its aiming direction in response to a change in curvature of the rail, whereby a stream of air from the nozzle impacts the determined portion during movement of the vehicle through the curvature of the rail.

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.

Abstract: A working fluid cassette for an intravascular heat exchange catheter includes a frame holding two closely spaced, square polymeric membranes in tension. Working fluid from the catheter is directed between the membranes. The cassette is closely received between two refrigerant cold plates to exchange heat with the working fluid, which is circulated back to the catheter.

Abstract: Compounds that inhibit HIF-2?, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by HIF-2?.

Abstract: A propulsion circuit for a vehicle includes an engine, a generator, a power rectifier, a direct current (DC) bus, a propulsion battery system, and at least one converter. The generator is coupled to the engine and configured to receive an input from the engine, and to provide an alternating current (AC) output. The power rectifier is configured to receive the AC output from the generator and provide a DC output responsive to receiving the AC output. The DC bus is coupled to the rectifier. The propulsion battery system is coupled to the DC bus. The at least one converter is configured to convert a direct current to an alternating current, and is coupled to the DC bus. Further, the propulsion circuit includes at least one charging component that is configured to selectably provide a charge to the battery system via at least one of the at least one converter.

Abstract: The present disclosure includes devices, systems and related methods useable for controlling a patient's body temperature by endovascular heat exchange as well as body surface heat exchange.

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.

Abstract: A closed loop catheter useable for heat exchange is manufactured by forming a plurality of generally transverse bore holes though a flexible, multilumen catheter body, lacing a tube trough the bore holes so that loops of the tube protrude from the catheter body, connecting one end of the tube to an inflow lumen of the catheter and connecting the other end of the tube to an outflow lumen of the catheter. A heated or cooled heat exchange medium may then be circulated through the tube while the catheter is inserted in the vasculature of a subject, thereby resulting in heat exchange between the subject's flowing blood and the heat exchange medium being circulated through the tube.

Abstract: A working fluid cassette for an intravascular heat exchange catheter includes a frame holding two closely spaced, square polymeric membranes in tension. Working fluid from the catheter is directed between the membranes. The cassette is closely received between two refrigerant cold plates to exchange heat with the working fluid, which is circulated back to the catheter.

Abstract: A device for dispensing a material having: a first surface with an orifice; a second surface opposite the first surface; a first endface comprising an annular opening; a second endface opposite the first endface; a cavity defined by the above. An actuator is anchored to the second surface and has at least a portion of a pressing pad extending through the orifice in the first surface. An inner side of the second surface comprises a contoured portion within the cavity, the contoured portion having a first end positioned toward the second endface and a second end positioned toward the first endface, wherein the contoured portion has a maximum height at or near the first end, and a minimum height at a position between the first end and the second end.