Abstract: Generation of multiple clocks having a synchronized phase relationship may reduce the size, complexity, power consumption, jitter and cost of circuitry while improving its functionality, performance, reliability and fault coverage. A multiple frequency clock generator may comprise an independent digital control oscillator (DCO) for generating a first clock and dependent DCOs for generating additional clocks that align at a common multiple frequency with the first clock with or without adjustment thereof. The independent and dependent DCOs may generate the first and additional clocks from a delay lock loop (DLL) by selecting a sequence of tap select signals. Tap select signals may be adjusted to maintain a desired phase and/or frequency of the first and additional clocks. Dependent DCOs may generate sequences of tap select signals based on the sequence of tap select signals generated by the independent DCO to incorporate adjustments, e.g., PLL error corrections.

Abstract: A clock generator includes a clock circuit and a voltage-controlled oscillator in a phase-locked loop. The clock circuit monitors input clock signals and selects one of the input clock signals based on characteristics of the input clock signals. The voltage-controlled oscillator generates a reference clock signal based on the selected clock signal. The clock circuit also includes synthesizers for generating clock signals, each of which has a frequency being a non-integer multiple of a frequency of the reference clock signal. Additionally, the clock circuit individually offsets the clock signals generated by the synthesizers relative to the reference clock signal. The clock generator is capable of switching the input clock signal during operation of the clock generator while maintaining the reference clock signal. Further, the clock generator is programmable to control operation of the clock circuit.

Abstract: The present invention describes the identification and isolation of chromones and novel chromone compositions from plant sources that exhibit up-regulation of adiponectin production by adipocytes and the normalization of virtually hundreds of genes related to glucose and fatty acid metabolic and signaling pathways. The chromone compositions are effective in enhancing adiponectin production by adipocytes and regulating genes involved in fatty acid biosynthesis, mitochondrial ?-oxidation of fatty acids, steroid biosynthesis, gluconeogenesis, fat transport, PPAR?/RXR? liver signaling and xenobiotic metabolism. The chromone compositions can be used to increase insulin sensitivity, improve glucose tolerance, lower triglyceride levels and balance glucose levels in mammals.

Abstract: The present invention implements a strategy that combines an enzyme inhibition assay with a chemical dereplication process to identify active plant extracts and the particular compounds—diarylalkanes and/or diarylalkanols within those extracts that specifically inhibit binuclear enzyme function. Included in the present invention are compositions of matter comprised of one or more of diarylalkanes and/or diarylalkanols, which inhibit the activity of binuclear enzymes, particularly tyrosinase and which prevent melanin overproduction. The present invention also provides a method for inhibiting the activity of a binuclear enzyme, particularly tyrosinase and a method for preventing and treating diseases and conditions related to binuclear enzyme function. The present invention further includes a method for preventing and treating melanin overproduction and diseases and conditions of the skin related thereto.

Abstract: A method for controlling lattice defects at a junction is described, which is used in accompany with an ion implantation step for forming a junction in a substrate and a subsequent annealing step. In the method, an extra implantation step is performed to increase the stress in the substrate apart from the junction, such that enhanced recrystallization is induced in the annealing step to lower the stress at the junction. The extra implantation step can be performed before or after the ion implantation step for forming the junction. A method for forming LDD or S/D regions of a CMOS device is also described, wherein at least one extra implantation step as mentioned above is performed before, between or after the ion implantation steps for forming the LDD or S/D regions of NMOS and PMOS transistors.

Abstract: A method for controlling lattice defects at a junction is described, which is used in accompany with an ion implantation step for forming a junction in a substrate and a subsequent annealing step. In the method, an extra implantation step is performed to increase the stress in the substrate apart from the junction, such that enhanced recrystallization is induced in the annealing step to lower the stress at the junction. The extra implantation step can be performed before or after the ion implantation step for forming the junction. A method for forming LDD or S/D regions of a CMOS device is also described, wherein at least one extra implantation step as mentioned above is performed before, between or after the ion implantation steps for forming the LDD or S/D regions of NMOS and PMOS transistors.

Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

Abstract: The present invention implements a strategy that combines an enzyme inhibition assay with a chemical dereplication process to identify active plant extracts and the particular compounds—diarylalkanes and/or diarylalkanols within those extracts that specifically inhibit binuclear enzyme function. Included in the present invention are compositions of matter comprised of one or more of diarylalkanes and/or diarylalkanols, which inhibit the activity of binuclear enzymes, particularly tyrosinase and which prevent melanin overproduction. The present invention also provides a method for inhibiting the activity of a binuclear enzyme, particularly tyrosinase and a method for preventing and treating diseases and conditions related to binuclear enzyme function. The present invention further includes a method for preventing and treating melanin overproduction and diseases and conditions of the skin related thereto.

Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

Abstract: In an SRAM for SNM measurement, the original word line of the SRAM cell for SNM measurement is divided into two segments for SNM measurement, wherein one segment is connected to the first node of the SRAM cell for SNM measurement, another segment is connected to the second node of the SRAM cell for SNM measurement. In addition, an adjacent word line adjacent to the SRAM cell for SNM measurement is connected to the SRAM cell for SNM measurement to form the word line of the SRAM cell. Therefore, the process of the SRAM for SNM measurement can be improved only by modifying the mask for the layout of the polysilicon layers in conventional ones.

Abstract: A method of testing for SRAM pull-down transistor sub-threshold leakage is disclosed. The method according to the present invention can detect the problem of changes in store state resulting form sub-threshold leakage current flow through the parasitic resistor in SRAM, and therefore provides an advantageous way for the manufacturer to eliminate the defective products and thereby improve the reliability of SRAM.