Abstract: Provided are a polymer medicament for treating hyperkalemia, and a preparation method thereof. Specifically, a polymer is provided, and the polymer includes repeating units obtained by polymerizing a monomer and a crosslinking agent. A molar ratio of the monomer to the crosslinking reagent ranges from 1:0.02 to 1:0.20. The monomer includes an acidic group and a pKa-reducing group next to the acidic group. The acidic group is selected from the group consisting of sulfonic acid group (—SO3—), sulfuric acid group (—OSO3—), carboxylic group (—CO2—), phosphonic acid group (—OPO32—), phosphate group (—OPO32—), and sulfamic acid group (—NHSO3—). The pKa-reducing group is selected from the group consisting of nitro, cyano, carbonyl, trifluoromethyl, and halogen atoms. The crosslinking agent has three or four reaction sites. The polymer can be used to treat hyperkalemia.

Abstract: The disclosure provides small molecule compounds, polymers, and compositions thereof, as well as methods for preparing such polymers and compositions. Also provided is a method of using the polymers or compositions thereof for binding uric acid or precursor thereof, and/or for treating hyperuricemia, gout, and/or diseases caused by hyperuricemia.

Abstract: The disclosure provides polymers and compositions thereof, as well as methods for preparing such polymers and compositions. Also provided is a method of using the polymers or compositions thereof for binding uric acid or precursor thereof, and/or for treating hyperuricemia, gout, and/or diseases caused by hyperuricemia.

Abstract: A method for facilitating a Parkinson's Disease (“PD”) assessment of a patient includes capturing first video of a patient performing first test movements while holding the mobile device; capturing second video of the patient performing second test movements while maintaining the mobile device on their person; capturing third video of the patient performing third test movements including standing and walking; capturing one or more IMU readings using an IMU of the mobile device; processing the first video, the second video, and the third video according to (i) a hand landmark model to generate one or more hand biomarkers, (ii) a face landmark model to generate one or more face biomarkers, and (iii) a body landmark model to generate one or more body biomarkers; and determining an assessment score based on a standardized PD assessment by processing the biomarkers.

Abstract: A self-organizing mesh network system is disclosed, comprising: at least one master node generating a timing reference signal; a plurality of regular nodes deriving time synchronization from the timing reference signal; and a wireless medium for communicating location and timestamp information among the plurality of regular nodes, The plurality of regular nodes may be configured to each use communicated location and timestamp information of nearby nodes to independently generate a location map of the nearby nodes. The plurality of regular nodes may be configured to accept an additional regular node. The plurality of regular nodes may be configured to allow a node of the plurality of regular nodes to exit the plurality of regular nodes. The plurality of regular nodes may each use communicated location and timestamp information of the plurality of regular nodes to independently generate a location map of each of the plurality of regular nodes.

Abstract: A rapid construction method for a secondary lining of a small-section tunnel includes steps of: transporting and store secondary lining steel bars to a designated position in the tunnel with a steel bar transport vehicle and a wheel type dump truck; after the tunnel is cleaned, simultaneously constructing the secondary lining from two ends to a middle of the tunnel; constructing a lower inverted arch with a customized inverted arch formwork and then constructing an upper arch wall with a plurality of portal arch wall formwork trolleys; wherein the portal arch wall formwork trolleys form a set, and are connected by hinges, so as to construct in a curve tunnel. The rapid construction method has a long single construction section, and procedure connection is compact, thereby realizing rapid and efficient construction of the secondary lining.

Abstract: A method of treating or preventing a Coronaviridae infection in a subject comprising administrating a therapeutically effective amount of a compound of Formula I or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the Coronaviridae comprises at least one selected from 2019-nCov virus, HCov 229E virus, SARS virus, MERS virus,

Abstract: A method of positioning using a shortest path based on a synthesized wideband channel estimate is described. In some embodiments, a method is disclosed, comprising: distributing an uplink schedule to a plurality of synchronized nodes; continuously capturing a reference signal across a plurality of carrier frequencies until frequency coverage for the synthetic wide band is achieved; removing frequency offset; calculating a plurality of channel estimates for the captured reference signal; aligning the plurality of channel estimates; combining the plurality of channel estimates to construct a single channel estimate of the synthetic wide band; deriving a shortest delay for the received reference signal; and using the derived shortest delay to estimate a time of arrival and thereby determine an estimated location.

Abstract: A tile or plate, includes: an upper plate (3) and a lower plate (4); wherein a plurality of heat conducting cavities (6) are uniformly provided between the upper plate (3) and the lower plate (4) via connecting ribs (5). A solar collection layer is provided on an upper surface of the tile or the plate. Two ends of the tile or the plate are connected with each of the plurality of the heat conducting cavities (6) via transverse connecting pipes (23, 37, 42). The transverse connecting pipes (23, 37, 42) of two neighboring tiles are connected by a ferrule (17) or a hose (36) to form an integrated circulation system. The tile or plate has a large day-lighting area and a high energy conversion rate.

Abstract: The present invention relates to a method of treating, preventing, or lessening postoperative cognitive dysfunction (POCD) in a subject in need thereof, the method comprising the step of administering to the subject a therapeutically effective amount of a compound of Formula I or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof,

Abstract: The present invention relates to a salt of a compound of formula (I) and uses thereof in medicine. Specifically, it relates to maleate of compound of formula (I) and pharmaceutically compositions thereof. Furthermore, the invention relates to the uses of maleate herein and pharmaceutically compositions thereof disclosed herein in the manufacture of a medicament, especially in the manufacture of a medicament for preventing, managing, treating or lessening hepatitis C virus (HCV) infection.

Abstract: A crystalline form A of the compound having formula (I) and uses thereof in medicine are described. Specifically, it relates to crystalline form A and pharmaceutically compositions thereof. Furthermore, it relates to the uses of crystalline form A disclosed herein and pharmaceutically compositions thereof disclosed herein in the manufacture of a medicament, especially in the manufacture of a medicament for preventing, managing, treating or lessening hepatitis C vims (HCV) infection.

Abstract: A full-circle secondary lining inverted arch construction formwork system for a long-distance tunnel and a formwork transporting method adopt a customized steel formwork, a steel pipe support, and a turn buckle. The steel pipe support is arranged on the longitudinal main edge, and is provided between the longitudinal rails and a primary lining for supporting vertical buoyancy. The turn buckle is arranged between two sides of the formwork and a reserved steel bar for resisting horizontal load generated during asymmetric pouring. A cantilever gantry crane and a transportation flat car are used for formwork transporting, wherein travel rails of the cantilever gantry crane and the transportation flat car are integrated on the customized steel formwork, and there is no other rail. According to the present, the formwork has high strength and rigidity, the formwork system is simple.

Abstract: A rapid construction method for a secondary lining of a small-section tunnel includes steps of: transporting and store secondary lining steel bars to a designated position in the tunnel with a steel bar transport vehicle and a wheel type dump truck; after the tunnel is cleaned, simultaneously constructing the secondary lining from two ends to a middle of the tunnel; constructing a lower inverted arch with a customized inverted arch formwork and then constructing an upper arch wall with a plurality of portal arch wall formwork trolleys; wherein the portal arch wall formwork trolleys form a set, and are connected by hinges, so as to construct in a curve tunnel. The rapid construction method has a long single construction section, and procedure connection is compact, thereby realizing rapid and efficient construction of the secondary lining.

Abstract: A coal measures fault formation simulation experimental device and a normal and reverse fault simulation experiment method relate to the field of similar material simulation experiment technology. The device includes a hydraulic lifting apparatus, a lower angle adjusting apparatus, a push rod apparatus, an upper loading apparatus, an upper angle adjusting apparatus, a lateral loading apparatus and a transparent side plate. The hydraulic lifting apparatus and the lower angle adjusting apparatus are below the experimental body, the upper loading apparatus and the upper angle adjusting apparatus are above the experimental body, the transparent side plate is disposed at a rear side surface of the experimental body, and the lateral loading apparatus is disposed at an end face of the experimental body.

Abstract: Provided are a normal fault simulation experiment device with an adjustable angle and an adjustable fracture initiation position and a method of using the same, which relate to the technical field of normal fault simulation experiments. The device includes a base, a column, a baffle plate, a hydraulic lifting apparatus, a lower angle adjusting apparatus, a push rod apparatus, an upper loading apparatus, an upper angle adjusting apparatus, a front baffle plate and a transparent side plate. The hydraulic lifting apparatus and the lower angle adjusting apparatus are disposed below an experimental body, the upper loading apparatus and the upper angle adjusting apparatus are disposed above the experimental body, the transparent side plate is disposed on a rear side surface of the experimental body, and a plurality of strip-shaped front baffle plates are disposed on a front side surface of the experimental body.

Abstract: Systems and methods for canceling carrier frequency offset (CFO) and sampling frequency offset (SFO) in a radio receive chain are disclosed. In one embodiment, a method is disclosed, comprising: receiving a sub-frame via a radio receive chain in a time domain; performing per-user filtering on the sub-frame to obtain a signal for a particular user; obtaining a CFO correction signal; adding the CFO correction signal in the time domain to perform a CFO correction step on the signal for the particular user; performing an FFT on the output of the CFO correction step to obtain samples in a frequency domain; adding an SFO correction signal in the frequency domain to perform an SFO correction to the output of FFT step; and demodulating the output of SFO correction step, thereby performing CFO and SFO correction while reducing inter-carrier interference (ICI).

Abstract: Provided are a normal fault simulation experiment device with an adjustable angle and an adjustable fracture initiation position and a method of using the same, which relate to the technical field of normal fault simulation experiments. The device includes a base, a column, a baffle plate, a hydraulic lifting apparatus, a lower angle adjusting apparatus, a push rod apparatus, an upper loading apparatus, an upper angle adjusting apparatus, a front baffle plate and a transparent side plate. The hydraulic lifting apparatus and the lower angle adjusting apparatus are disposed below an experimental body, the upper loading apparatus and the upper angle adjusting apparatus are disposed above the experimental body, the transparent side plate is disposed on a rear side surface of the experimental body, and a plurality of strip-shaped front baffle plates are disposed on a front side surface of the experimental body.

Abstract: A coal measures fault formation simulation experimental device and a normal and reverse fault simulation experiment method relate to the field of similar material simulation experiment technology. The device includes a hydraulic lifting apparatus, a lower angle adjusting apparatus, a push rod apparatus, an upper loading apparatus, an upper angle adjusting apparatus, a lateral loading apparatus and a transparent side plate. The hydraulic lifting apparatus and the lower angle adjusting apparatus are below the experimental body, the upper loading apparatus and the upper angle adjusting apparatus are above the experimental body, the transparent side plate is disposed at a rear side surface of the experimental body, and the lateral loading apparatus is disposed at an end face of the experimental body.

Abstract: Systems and methods are disclosed herein for blind frequency synchronization.